Genes that may modulate longevity in C. elegans in both dauer larvae and long-lived daf-2 adults

Experimental Gerontology

Volumn 42, Issue 8, 2007, Pages 825-839

  Ruzanov, Peter ^a   Riddle, Donald L ^b   Marra, Marco A ^a   McKay, Sheldon J ^a   Jones, Steven M ^a  

^a BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Aging; C. elegans; Gene expression; Longevity; Reactive oxygen species

Indexed keywords

GLYOXYLIC ACID;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CAENORHABDITIS ELEGANS; CITRIC ACID CYCLE; CONTROLLED STUDY; DNA LIBRARY; ELECTRON TRANSPORT; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; LARVA; LONGEVITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SERIAL ANALYSIS OF GENE EXPRESSION;

AGING; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CITRIC ACID CYCLE; ELECTRON TRANSPORT COMPLEX III; ELECTRON TRANSPORT COMPLEX IV; GENE EXPRESSION PROFILING; GENES, HELMINTH; LARVA; LONGEVITY; MODELS, BIOLOGICAL; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REACTIVE OXYGEN SPECIES; RECEPTOR, INSULIN; RNA INTERFERENCE; RNA, HELMINTH; RNA, MESSENGER;

CAENORHABDITIS ELEGANS; NEMATODA;

EID: 34447341453     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2007.04.002     Document Type: Article

References (69)

1. Ashrafi K., Chang F.Y., Watts J.L., Fraser A.G., Kamath R.S., Ahringer J., and Ruvkun G. Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature 421 (2003) 268-272
2. Audic S., and Claverie J.-M. The significance of digital gene expression profiles. Genome Res. 7 (1997) 986-995
3. Balaban R.S., Nemoto S., and Finkel T. Mitochondria oxidants, and aging. Cell 120 (2005) 483-495
4. Barja G. Free radicals and aging. Trends Neurosci. 27 (2004) 595-600
5. Barros M.H., Bandy B., Tahara E.B., and Kowaltowski A.J. Higher respiratory activity decreases mitochondrial reactive oxygen release and increases lifespan in Saccharomyces cerevisiae. J. Biol. Chem. 279 (2004) 49883-49888
6. Braeckman B.P., Houthoofd K., Brys K., Lenaerts I., De Vreese A., Van Eygen S., Raes H., and Vanfleteren J.R. No reduction of energy metabolism in Clk mutants. Mech. Ageing Dev. 123 (2002) 1447-1456
7. Brand M.D. Uncoupling to survive? The role of mitochondrial inefficiency in aging. Exp. Gerontol. 35 (2000) 811-820
8. Dillin A., Hsu A.L., Arantes-Oliveira N., Lehrer-Graiwer J., Hsin H., Fraser A.G., Kamath R.S., Ahringer J., and Kenyon C. Rates of behavior and aging specified by mitochondrial function during development. Science 298 (2002) 2398-2401
9. Djavan B., Waldert M., Seitz C., and Marberger M. Insulin-like growth factors and prostate cancer. World J. Urol. 19 (2001) 225-233
10. Ewing B., and Green P. Base-calling of automated sequencer traces using phred. II Error probabilities. Genome Res. 8 (1998) 186-194
11. Ewing B., Hillier L., Wendl M.C., and Green P. Base-calling of automated sequencer traces using phred. I Accuracy assessment. Genome Res. 8 (1998) 175-185
12. Finch C.E., and Ruvkun G. The genetics of aging. Annu. Rev. Genomics Hum. Genet. 2 (2001) 435-462
13. Freedman J.H., Slice L.W., Dixon D., Fire A., and Rubin C.S. The novel metallothionein genes of Caenorhabditis elegans. Structural organization and inducible, cell-specific expression. J. Biol. Chem. 268 (1993) 2554-2564
14. Friedman D.B., and Johnson T.E. A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility. Genetics 118 (1988) 75-86
15. Gems D., Sutton A.J., Sundermeyer M.L., Albert P.S., King K.V., Edgley M.L., Larsen P.L., and Riddle D.L. Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans. Genetics 150 (1998) 129-155
16. Golden J.W., and Riddle D.L. The Caenorhabditis elegans dauer larva: developmental effects of pheromone, food, and temperature. Dev. Biol. 102 (1984) 368-378
17. Griffith O.L., Pleasance E.D., Fulton D.L., Oveisi M., Ester M., Siddiqui A.S., and Jones S.J. Assessment and integration of publicly available SAGE, cDNA microarray, and oligonucleotide microarray expression data for global coexpression analyses. Genomics 86 (2005) 476-488
18. Halaschek-Wiener J., Khattra J.S., McKay S., Pouzyrev A., Stott J.M., Yang G.S., Holt R.A., Jones S.J., Marra M.A., Brooks-Wilson A.R., and Riddle D.L. Analysis of long-lived C. elegans daf-2 mutants using serial analysis of gene expression. Genome Res. 15 (2005) 603-615
19. Hamilton B., Dong Y., Shindo M., Liu W., Odell I., Ruvkun G., and Lee S.S. A systematic RNAi screen for longevity genes in C. elegans. Genes Dev. 19 (2005) 1544-1555
20. Hansen M., Hsu A.L., Dillin A., and Kenyon C. New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic. RNAi screen. PLoS Genetics 1 (2005) 119-128
21. Harman D. The biologic clock: the mitochondria?. J. Am. Geriatr. Soc. 20 (1972) 145-147
22. Herrmann P.C., Gillespie J.W., Charboneau L., Bichsel V.E., Paweletz C.P., Calvert V.S., Kohn E.C., Emmert-Buck M.R., Liotta L.A., and Petricoin E.F.r. Mitochondrial proteome: altered cytochrome c oxidase subunit levels in prostate cancer. Proteomics 3 (2003) 1801-1810
23. Holt S.J., and Riddle D.L. SAGE surveys C. elegans carbohydrate metabolism: evidence for an anaerobic shift in the long-lived dauer larva. Mech. Ageing Dev. 124 (2003) 779-800
24. Houthoofd K., Fidalgo M.A., Hoogewijs D., Braeckman B.P., Lenaerts I., Brys K., Matthijssens F., De Vreese A., Van Eygen S., Munoz M.J., and Vanfleteren J.R. Metabolism, physiology and stress defense in three aging Ins/IGF-1 mutants of the nematode Caenorhabditis elegans. Aging Cell 4 (2005) 87-95
25. Jazwinski S.M. Aging and longevity genes. Acta Biochim. Pol. 47 (2000) 269-279
26. Jerome L., Shiry L., and Leyland-Jones B. Deregulation of the IGF axis in cancer: epidemiological evidence and potential therapeutic interventions. Endocr. Relat. Cancer 10 (2003) 561-578
27. Jia K., Chen D., and Riddle D.L. The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development 131 (2004) 3897-3906
28. Johnson T.E. Advantages and disadvantages of Caenorhabditis elegans for aging research. Exp. Gerontol. 38 (2003) 1329-1332
29. Jones S.J., Riddle D.L., Pouzyrev A.T., Velculescu V.E., Hillier L., Eddy S.R., Stricklin S.L., Baillie D.L., Waterston R., and Marra M.A. Changes in gene expression associated with developmental arrest and longevity in Caenorhabditis elegans. Genome Res. 11 (2001) 1346-1352
30. Jung D.J., Sung H.S., Goo Y.W., Lee H.M., Park O.K., Jung S.Y., Lim J., Kim H.J., Lee S.K., Kim T.S., Lee J.W., and Lee Y.C. Novel transcription coactivator complex containing activating signal cointegrator 1. Mol. Cell Biol. 22 (2002) 5203-5211
31. Kamath R.S., Fraser A.G., Dong Y., Poulin G., Durbin R., Gotta M., Kanapin A., Le Bot N., Moreno S., Sohrmann M., Welchman D.P., Ziperlen P., and Ahringer J. Systemic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421 (2003) 231-237
32. Kenyon C., Chang J., Gensch E., Rudner A., and Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature 366 (1993) 461-464
33. Kimura K.D., Tissenbaum H.A., Liu Y., and Ruvkun G. daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277 (1997) 942-946
34. Klass M., and Hirsh D. Non-ageing developmental variant of Caenorhabditis elegans. Nature 260 (1976) 523-525
35. Kroll J. The molecular chaperones and the phenomena of cellular immortalization and apoptosis in vitro. Ann. N. Y. Acad. Sci. 1019 (2004) 568-571
36. Kuzmin E.V., Karpova O.V., Elthon T.E., and Newton K.J. Mitochondrial respiratory deficiencies signal up-regulation of genes for heat shock proteins. J. Biol. Chem. 279 (2004) 20672-20677
37. Lehr H.A., Mankoff D.A., Corwin D., Santeusanio G., and Gown A.M. Application of photoshop-based image analysis to quantification of hormone receptor expression in breast cancer. J. Histochem. Cytochem. 45 (1997) 1559-1565
38. Lin K., Dorman J.B., Rodan A., and Kenyon C. daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 278 (1997) 1319-1322
39. Lin S.J., Ford E., Haigis M., Liszt G., and Guarente L. Calorie restriction extends yeast life span by lowering the level of NADH. Genes Dev. 18 (2004) 12-16
40. Linnane A.W., Kovalenko S., and Gingold E.B. The Universality of Bioenergetic desease. Age-associated cellular bioenergetic degradation and amelioration therapy. Ann. N. Y. Acad. Sci. 854 (1998) 202-213
41. Lund J., Tedesco P., Duke K., Wang J., Kim S., and Johnson T. Transcriptional Profile of Aging in C. elegans. Curr. Biol. 12 (2002) 1566-1573
42. Luo Y. Long-lived worms and aging. Redox Rep. 9 (2004) 65-69
43. McElwee J., Bubb K., and Thomas J.H. Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16. Aging Cell 2 (2003) 111-121
44. McElwee J.J., Schuster E., Blanc E., Thomas J.H., and Gems D. Shared transcriptional signature in Caenorhabditis elegans dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance. J. Biol. Chem. 279 (2004) 44533-44543
45. McElwee J.J., Schuster E., Blanc E., Thornton J., and Gems D. Diapause-associated metabolic traits reiterated in long-lived daf-2 mutants in the nematode Caenorhabditis elegans. Mech. Ageing Dev. 127 (2006) 458-472
46. McKay S.J., Johnsen R., Khattra J., Asano J., Baillie D.L., Chan S., Dube N., Fang L., Goszczynski B., Ha E., Halfnight E., Hollebakken R., Huang P., Hung K., Jensen V., Jones S.J., Kai H., Li D., Mah A., Marra M., McGhee J., Newbury R., Pouzyrev A., Riddle D.L., Sonnhammer E., Tian H., Tu D., Tyson J.R., Vatcher G., Warner A., Wong K., Zhao Z., and Moerman D.G. Gene expression profiling of cells, tissues, and developmental stages of the nematode C. elegans. Cold Spring Harb. Symp. Quant. Biol. 68 (2003) 159-169
47. Melendez A., Talloczy Z., Seaman M., Eskelinen E.L., Hall D.H., and Levine B. Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science 301 (2003) 1387-1391
48. Morrow G., and Tanguay R. Heat shock proteins and aging in Drosophila melanogaster. Semin. Cell Dev. Biol. 14 (2003) 291-299
49. Murphy C.T., McCarroll S.A., Bargmann C.I., Fraser A., Kamath R.S., Ahringer J., Li H., and Kenyon C. Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424 (2003) 277-283
50. O'Riordan V.B., and Burnell A.M. Intermediary metabolism in the dauer larva of the nematode Caenorhabditis elegans. II. The glyoxalate cycle and fatty-acid oxidation. Comp. Biochem. Physiol. 95B (1990) 233-238
51. Ogg S., Paradis S., Gottlieb S., Patterson G.I., Lee L., Tissenbaum H.A., and Ruvkun G. The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 389 (1997) 994-999
52. Pleasance E.D., Marra M.A., and Jones S.J. Assessment of SAGE in transcript identification. Genome Res. 13 (2003) 1203-1215
53. Rea S., and Johnson T.E. A metabolic model for life span determination in Caenorhabditis elegans. Dev. Cell 5 (2003) 197-203
54. Roberts T.M., and Ward S. Centripetal flow of pseudopodial surface components could propel the amoeboid movement of Caenorhabditis elegans spermatozoa. J. Cell Biol. 92 1 (1982) 132-138
55. Saha S., Sparks A.B., Rago C., Akmaev V., Wang C.J., Vogelstein B., Kinzler K.W., and Velculescu V.E. Using the transcriptome to annotate the genome. Nat. Biotechnol. 20 (2002) 508-512
56. Sambrook J., and Russel D.W. Molecular Cloning: A Laboratory Manual (2001), Cold Spring Harbor, New York
57. Singh K.K. Mitochondrial dysfunction is a common phenotype in aging and cancer. Ann. N. Y. Acad. Sci. 1019 (2004) 2660-2664
58. Sonnichsen B., Koski L.B., Walsh A., Marschall P., Neumann B., Brehm M., Alleaume A.M., Artelt J., Bettencourt P., Cassin E., Hewitson M., Holz C., Khan M., Lazik S., Martin C., Nitzsche B., Ruer M., Stamford J., Winzi M., Heinkel R., Roder M., Finell J., Hantsch H., Jones S.J., Jones M., Piano F., Gunsalus K.C., Oegema K., Gonczy P., Coulson A., Hyman A.A., and Echeverri C.J. Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. Nature 434 (2005) 462-469
59. Soti C., and Csermely P. Aging and molecular chaperones. Exp. Gerontol. 38 (2003) 1037-1040
60. Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N., Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P., Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W., Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A., Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E., Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K., Durbin R., and Waterston R.H. The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics. PLoS Biol. 1 (2003) E45
61. Tatar M., Bartke A., and Antebi A. The endocrine regulation of aging by insulin-like signals. Science 299 (2003) 1346-1351
62. The Gene Ontology Consortium, 2000. Gene Ontology: tool for the unification of biology. Nat. Genet. 25, 25-29.
63. Tissenbaum H.A., and Ruvkun G. An insulin-like signaling pathway affects both longevity and reproduction in Caenorhabditis elegans. Genetics 148 (1998) 703-717
64. van Ruissen F., Ruijter J.M., Schaaf G.J., Asgharnegad L., Zwijnenburg D.A., Kool M., and Baas F. Evaluation of the similarity of gene expression data estimated with SAGE and Affymetrix GeneChips. BMC Genomics 6 (2005) 91
65. Vanfleteren J.R., and De Vreese A. The gerontogenes age-1 and daf-2 determine metabolic rate potential in aging Caenorhabditis elegans. FASEB J. 9 (1995) 1355-1361
66. Velculescu V.E., Zhang L., Vogelstein B., and Kinzler K.W. Serial analysis of gene expression. Science 270 (1995) 484-487
67. Wadsworth W.G., and Riddle D.L. Developmental regulation of energy metabolism in Caenorhabditis elegans. Dev. Biol. 132 (1989) 167-173
68. Walker G.A., and Lithgow G.J. Lifespan extension in C. elegans by a molecular chaperone dependent upon insulin-like signals. Aging Cell 2 (2003) 131-139
69. Weinert B.T., and Timiras P.S. Invited review: theories of aging. J. Appl. Physiol. 95 (2003) 1706-1716