메뉴 건너뛰기




Volumn 16, Issue 10, 2007, Pages 1157-1163

PTEN regulates phospholipase D and phospholipase C

Author keywords

[No Author keywords available]

Indexed keywords

GLYCEROPHOSPHOLIPID; PHOSPHATIDIC ACID; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLINOSITOL 3,4,5 BISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHOLIPASE C; PHOSPHOLIPASE D; PROTEIN KINASE B; UNCLASSIFIED DRUG;

EID: 34447321313     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddm063     Document Type: Article
Times cited : (18)

References (41)
  • 4
    • 6844252284 scopus 로고    scopus 로고
    • Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation
    • Marsh, D.J., Coulon, V., Lunetta, K.L., Rocca-Serra, P., Dahia, P.L., Zheng, Z., Liaw, D., Caron, S., Duboue, B., Lin, A.Y. et al. (1998) Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation. Hum. Mol. Genet., 7, 507-515.
    • (1998) Hum. Mol. Genet , vol.7 , pp. 507-515
    • Marsh, D.J.1    Coulon, V.2    Lunetta, K.L.3    Rocca-Serra, P.4    Dahia, P.L.5    Zheng, Z.6    Liaw, D.7    Caron, S.8    Duboue, B.9    Lin, A.Y.10
  • 5
    • 0035928416 scopus 로고    scopus 로고
    • Association of germline mutation in the PTEN tumour suppressor gene and Proteus and Proteus-like syndromes
    • Zhou, X., Hampel, H., Thiele, H., Gorlin, R.J., Hennekam, R.C., Parisi, M., Winter, R.M. and Eng, C. (2001) Association of germline mutation in the PTEN tumour suppressor gene and Proteus and Proteus-like syndromes. Lancet, 358, 210-211.
    • (2001) Lancet , vol.358 , pp. 210-211
    • Zhou, X.1    Hampel, H.2    Thiele, H.3    Gorlin, R.J.4    Hennekam, R.C.5    Parisi, M.6    Winter, R.M.7    Eng, C.8
  • 6
    • 0041742215 scopus 로고    scopus 로고
    • Germline PTEN promoter mutations and deletions in Cowden/ Bannayan-Riley-Ruvalcaba syndrome result in aberrant PTEN protein and dysregulation of the phosphoinositol-3-kinase/Akt pathway
    • Zhou, X.P., Waite, K.A., Pilarski, R., Hampel, H., Fernandez, M.J., Bos, C., Dasouki, M.J., Feldman, G.L., Greenberg, L.A., Ivanovich, J.L. et al. (2003) Germline PTEN promoter mutations and deletions in Cowden/ Bannayan-Riley-Ruvalcaba syndrome result in aberrant PTEN protein and dysregulation of the phosphoinositol-3-kinase/Akt pathway. Am. J. Hum. Genet., 73, 404-411.
    • (2003) Am. J. Hum. Genet , vol.73 , pp. 404-411
    • Zhou, X.P.1    Waite, K.A.2    Pilarski, R.3    Hampel, H.4    Fernandez, M.J.5    Bos, C.6    Dasouki, M.J.7    Feldman, G.L.8    Greenberg, L.A.9    Ivanovich, J.L.10
  • 7
    • 16944362877 scopus 로고    scopus 로고
    • The role of MMAC1 mutations in early-onset breast cancer: Causative in association with Cowden syndrome and excluded in BRCA1-negative cases
    • Tsou, H.C., Teng, D.H., Ping, X.L., Brancolini, V., Davis, T., Hu, R., Xie, X.X., Gruener, A.C., Schrager, C.A., Christiano, A.M. et al. (1997) The role of MMAC1 mutations in early-onset breast cancer: causative in association with Cowden syndrome and excluded in BRCA1-negative cases. Am. J. Hum. Genet., 61, 1036-1043.
    • (1997) Am. J. Hum. Genet , vol.61 , pp. 1036-1043
    • Tsou, H.C.1    Teng, D.H.2    Ping, X.L.3    Brancolini, V.4    Davis, T.5    Hu, R.6    Xie, X.X.7    Gruener, A.C.8    Schrager, C.A.9    Christiano, A.M.10
  • 9
    • 0032853452 scopus 로고    scopus 로고
    • PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome
    • Marsh, D.J., Kum, J.B., Lunetta, K.L., Bennett, M.J., Gorlin, R.J., Ahmed, S.F., Bodurtha, J., Crowe, C., Curtis, M.A., Dasouki, M. et al. (1999) PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome. Hum Mol. Genet., 8, 1461-1472.
    • (1999) Hum Mol. Genet , vol.8 , pp. 1461-1472
    • Marsh, D.J.1    Kum, J.B.2    Lunetta, K.L.3    Bennett, M.J.4    Gorlin, R.J.5    Ahmed, S.F.6    Bodurtha, J.7    Crowe, C.8    Curtis, M.A.9    Dasouki, M.10
  • 10
    • 0030801275 scopus 로고    scopus 로고
    • Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas
    • Rhei, E., Kang, L., Bogomolniy, F., Federici, M.G., Borgen, P.I. and Boyd, J. (1997) Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas. Cancer Res., 57, 3657-3659.
    • (1997) Cancer Res , vol.57 , pp. 3657-3659
    • Rhei, E.1    Kang, L.2    Bogomolniy, F.3    Federici, M.G.4    Borgen, P.I.5    Boyd, J.6
  • 11
    • 0031916211 scopus 로고    scopus 로고
    • Sporadic breast cancers exhibit loss of heterozygosity on chromosome segment 10q23 close to the Cowden disease locus
    • Singh, B., Ittmann, M.M. and Krolewski, J.J. (1998) Sporadic breast cancers exhibit loss of heterozygosity on chromosome segment 10q23 close to the Cowden disease locus. Genes Chromosomes Cancer, 21, 166-171.
    • (1998) Genes Chromosomes Cancer , vol.21 , pp. 166-171
    • Singh, B.1    Ittmann, M.M.2    Krolewski, J.J.3
  • 13
    • 0042316755 scopus 로고    scopus 로고
    • PTEN: One gene, many syndromes
    • Eng, C. (2003) PTEN: One gene, many syndromes. Hum. Mutat., 22 183-198.
    • (2003) Hum. Mutat , vol.22 , pp. 183-198
    • Eng, C.1
  • 14
    • 0035869212 scopus 로고    scopus 로고
    • PTEN coordinates G1 arrest by down regulating cyclin D1 via its protein phosphatase activity and up regulating p27 via its lipid phosphatase activity
    • Weng, L.P., Brown, J.L. and Eng, C. (2001) PTEN coordinates G1 arrest by down regulating cyclin D1 via its protein phosphatase activity and up regulating p27 via its lipid phosphatase activity. Hum. Mol. Genet. 10, 599-604.
    • (2001) Hum. Mol. Genet , vol.10 , pp. 599-604
    • Weng, L.P.1    Brown, J.L.2    Eng, C.3
  • 15
    • 0035869175 scopus 로고    scopus 로고
    • PTEN inhibits insulin-stimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1./Grb-2/Sos complex formation in a breast cancer model
    • Weng, L.P., Smith, W.M., Brown, J.L. and Eng, C. (2001) PTEN inhibits insulin-stimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1./Grb-2/Sos complex formation in a breast cancer model. Hum. Mol. Genet., 10, 605-616.
    • (2001) Hum. Mol. Genet , vol.10 , pp. 605-616
    • Weng, L.P.1    Smith, W.M.2    Brown, J.L.3    Eng, C.4
  • 16
    • 0035253607 scopus 로고    scopus 로고
    • PTEN induces apoptosis and cell cycle arrest through phosphoinositol-3-kinase/Akt-dependent and -independent pathways
    • Weng, L., Brown, J. and Eng, C. (2001) PTEN induces apoptosis and cell cycle arrest through phosphoinositol-3-kinase/Akt-dependent and -independent pathways. Hum. Mol. Genet., 10, 237-242.
    • (2001) Hum. Mol. Genet , vol.10 , pp. 237-242
    • Weng, L.1    Brown, J.2    Eng, C.3
  • 17
    • 0032577699 scopus 로고    scopus 로고
    • The tumor suppressor, PTEN/MMACI, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
    • Maehama, T. and Dixon, J.E. (1998) The tumor suppressor, PTEN/MMACI, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem., 273, 13375-13378.
    • (1998) J. Biol. Chem , vol.273 , pp. 13375-13378
    • Maehama, T.1    Dixon, J.E.2
  • 18
    • 0030948743 scopus 로고    scopus 로고
    • New developments in phospholipase D
    • Exton, J.H. (1997) New developments in phospholipase D. J. Biol. Chem., 272, 15579-15582.
    • (1997) J. Biol. Chem , vol.272 , pp. 15579-15582
    • Exton, J.H.1
  • 19
    • 0028625762 scopus 로고
    • Participation of diacylglycerol kinase in mitogenic signal transduction. induced by platelet-derived growth factor in vascular smooth muscle cells
    • Inui, H., Kondo, T., Konishi, F., Kitami, Y. and Inagami, T. (1994) Participation of diacylglycerol kinase in mitogenic signal transduction. induced by platelet-derived growth factor in vascular smooth muscle cells. Biochem. Biophys. Res. Commun., 205, 1338-1344.
    • (1994) Biochem. Biophys. Res. Commun , vol.205 , pp. 1338-1344
    • Inui, H.1    Kondo, T.2    Konishi, F.3    Kitami, Y.4    Inagami, T.5
  • 20
    • 0023229006 scopus 로고
    • Phosphatidylethanol formation via transphosphatidylation by rat brain synaptosomal phospholipase D
    • Kobayashi, M. and Kanfer, J.N. (1987) Phosphatidylethanol formation via transphosphatidylation by rat brain synaptosomal phospholipase D. J. Neurochem., 48, 1597-1603.
    • (1987) J. Neurochem , vol.48 , pp. 1597-1603
    • Kobayashi, M.1    Kanfer, J.N.2
  • 21
    • 0242288646 scopus 로고    scopus 로고
    • Regulation of PTEN (phosphatase and tensin homolog deleted on chromosome 10) expression by estradiol and progesterone in human endometrium
    • Guzeloglu-Kayisli, O., Kayisli, U.A., Al-Rejjal, R., Zheng, W., Luleci, G. and Arici, A. (2003) Regulation of PTEN (phosphatase and tensin homolog deleted on chromosome 10) expression by estradiol and progesterone in human endometrium. J. Clin. Endocrinol. Metab., 88, 5017-5026.
    • (2003) J. Clin. Endocrinol. Metab , vol.88 , pp. 5017-5026
    • Guzeloglu-Kayisli, O.1    Kayisli, U.A.2    Al-Rejjal, R.3    Zheng, W.4    Luleci, G.5    Arici, A.6
  • 22
    • 12144262323 scopus 로고    scopus 로고
    • The molecular pharmacology of estrogen receptor modulators: Implications for the treatment of breast cancer
    • s
    • McDonnell, D.P. (2005) The molecular pharmacology of estrogen receptor modulators: Implications for the treatment of breast cancer. Clin. Cancer Res., 11, 871s-877s.
    • (2005) Clin. Cancer Res , vol.11
    • McDonnell, D.P.1
  • 23
    • 0025800131 scopus 로고
    • PLC-alpha: A common mediator of the action of estrogen and other hormones?
    • Mobbs, C.V., Kaplitt, M., Kow, L.M. and Pfaff, D.W. (1991) PLC-alpha: A common mediator of the action of estrogen and other hormones? Mol. Cell. Endocrinol., 80, C187-C191.
    • (1991) Mol. Cell. Endocrinol , vol.80
    • Mobbs, C.V.1    Kaplitt, M.2    Kow, L.M.3    Pfaff, D.W.4
  • 24
    • 0027460649 scopus 로고
    • Rapid and long-term effects of 17 beta-estradiol on PIP2-phospholipase C-specific activity of MCF-7 cells
    • Graber, R., Sumida, C., Vallette, G. and Nunez, E.A. (1993) Rapid and long-term effects of 17 beta-estradiol on PIP2-phospholipase C-specific activity of MCF-7 cells. Cell. Signal., 5, 181-186.
    • (1993) Cell. Signal , vol.5 , pp. 181-186
    • Graber, R.1    Sumida, C.2    Vallette, G.3    Nunez, E.A.4
  • 25
    • 0030037396 scopus 로고    scopus 로고
    • Activation of phospholipase D and phosphatidylinositol 4-phosphate 5-kinase in HL60 membranes is mediated by endogenous Arf but not Rho
    • Martin, A., Brown, F.D., Hodgkin, M.N., Bradwell, A.J., Cook, S.J., Hart, M. and Wakelam, M.J. (1996) Activation of phospholipase D and phosphatidylinositol 4-phosphate 5-kinase in HL60 membranes is mediated by endogenous Arf but not Rho. J. Biol. Chem., 271, 17397-17403.
    • (1996) J. Biol. Chem , vol.271 , pp. 17397-17403
    • Martin, A.1    Brown, F.D.2    Hodgkin, M.N.3    Bradwell, A.J.4    Cook, S.J.5    Hart, M.6    Wakelam, M.J.7
  • 26
    • 31544466778 scopus 로고    scopus 로고
    • Phospholipase D prevents etoposide-induced apoptosis by inhibiting the expression of early growth response-1 and phosphatase and tensin homologue deleted on chromosome 10
    • Kim, J., Lee, Y.H., Kwon, T.K., Chang, J.S., Chung, K.C. and Min, D.S. (2006) Phospholipase D prevents etoposide-induced apoptosis by inhibiting the expression of early growth response-1 and phosphatase and tensin homologue deleted on chromosome 10. Cancer Res., 66, 784-793.
    • (2006) Cancer Res , vol.66 , pp. 784-793
    • Kim, J.1    Lee, Y.H.2    Kwon, T.K.3    Chang, J.S.4    Chung, K.C.5    Min, D.S.6
  • 27
    • 0027049381 scopus 로고
    • Calcium-activated phosphatidylcholine-specific phospholipase C and D in MDCK epithelial cells
    • Peterson, M.W. and Walter, M.E. (1992) Calcium-activated phosphatidylcholine-specific phospholipase C and D in MDCK epithelial cells. Am J. Physiol., 263, C1216-C1224.
    • (1992) Am J. Physiol , vol.263
    • Peterson, M.W.1    Walter, M.E.2
  • 28
    • 0344653108 scopus 로고    scopus 로고
    • Activation of phospholipase C-gamma by phosphatidylinositol 3,4,5-trisphosphate
    • Bae, Y.S., Cantley, L.G., Chen, C.S., Kim, S.R., Kwon, K.S. and Rhee, S.G. (1998) Activation of phospholipase C-gamma by phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem., 273, 4465-4469.
    • (1998) J. Biol. Chem , vol.273 , pp. 4465-4469
    • Bae, Y.S.1    Cantley, L.G.2    Chen, C.S.3    Kim, S.R.4    Kwon, K.S.5    Rhee, S.G.6
  • 29
    • 0032518666 scopus 로고    scopus 로고
    • Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting
    • Falasca, M., Logan, S.K., Lehto, V.P., Baccante, G., Lemmon, M.A. and Schlessinger, J. (1998) Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting. EMBO J., 17, 414-422.
    • (1998) EMBO J , vol.17 , pp. 414-422
    • Falasca, M.1    Logan, S.K.2    Lehto, V.P.3    Baccante, G.4    Lemmon, M.A.5    Schlessinger, J.6
  • 30
    • 0033534687 scopus 로고    scopus 로고
    • Phospholipase D and its product, phosphatidic acid, mediate agonist-dependent raf-1 translocation to the plasma membrane and the activation of the mitogen-activated protein kinase pathway
    • Rizzo, M.A., Shome, K., Vasudevan, C., Stolz, D.B., Sung, T.C., Frohman, M.A., Watkins, S.C. and Romero, G. (1999) Phospholipase D and its product, phosphatidic acid, mediate agonist-dependent raf-1 translocation to the plasma membrane and the activation of the mitogen-activated protein kinase pathway. J. Biol. Chem., 274 1131-1139.
    • (1999) J. Biol. Chem , vol.274 , pp. 1131-1139
    • Rizzo, M.A.1    Shome, K.2    Vasudevan, C.3    Stolz, D.B.4    Sung, T.C.5    Frohman, M.A.6    Watkins, S.C.7    Romero, G.8
  • 31
    • 0035159121 scopus 로고    scopus 로고
    • Role for phospholipase D in receptor-mediated endocytosis
    • Shen, Y., Xu, L. and Foster, D.A. (2001) Role for phospholipase D in receptor-mediated endocytosis. Mol. Cell. Biol., 21, 595-602.
    • (2001) Mol. Cell. Biol , vol.21 , pp. 595-602
    • Shen, Y.1    Xu, L.2    Foster, D.A.3
  • 32
    • 0141542631 scopus 로고    scopus 로고
    • Phospholipase D in cell proliferation and cancer
    • Foster, D.A. and Xu, L. (2003) Phospholipase D in cell proliferation and cancer. Mol. Cancer Res., 1, 789-800.
    • (2003) Mol. Cancer Res , vol.1 , pp. 789-800
    • Foster, D.A.1    Xu, L.2
  • 33
    • 0037118585 scopus 로고    scopus 로고
    • Phospholipase D overcomes cell cycle arrest induced by high-intensity Raf signaling
    • Joseph, T., Bryant, A., Frankel, P., Wooden, R., Kerkhoff, E., Rapp, U.R. and Foster, D.A. (2002) Phospholipase D overcomes cell cycle arrest induced by high-intensity Raf signaling. Oncogene, 21, 3651-3658.
    • (2002) Oncogene , vol.21 , pp. 3651-3658
    • Joseph, T.1    Bryant, A.2    Frankel, P.3    Wooden, R.4    Kerkhoff, E.5    Rapp, U.R.6    Foster, D.A.7
  • 34
    • 0037436828 scopus 로고    scopus 로고
    • Phospholipase D prevents apoptosis in v-Src-transformed rat fibroblasts and MDA-MB-231 breast cancer cells
    • Zhong, M., Shen, Y., Zheng, Y., Joseph, T., Jackson, D. and Foster, D.A. (2003) Phospholipase D prevents apoptosis in v-Src-transformed rat fibroblasts and MDA-MB-231 breast cancer cells. Biochem. Biophys. Res. Commun., 302, 615-619.
    • (2003) Biochem. Biophys. Res. Commun , vol.302 , pp. 615-619
    • Zhong, M.1    Shen, Y.2    Zheng, Y.3    Joseph, T.4    Jackson, D.5    Foster, D.A.6
  • 35
    • 0033571477 scopus 로고    scopus 로고
    • PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death
    • Weng, L.P., Smith, W.M., Dahia, P.L., Ziebold, U., Gil, E., Lees, J.A. and Eng, C. (1999) PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death. Cancer Res., 59, 5808-5814.
    • (1999) Cancer Res , vol.59 , pp. 5808-5814
    • Weng, L.P.1    Smith, W.M.2    Dahia, P.L.3    Ziebold, U.4    Gil, E.5    Lees, J.A.6    Eng, C.7
  • 36
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipids from animal tissues
    • Folch, J., Lees, M. and Soane, G.H. (1957) A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem., 226, 497-509.
    • (1957) J. Biol. Chem , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Soane, G.H.3
  • 37
    • 0037119432 scopus 로고    scopus 로고
    • Phospholipase D activation by sphingosine 1-phosphate regulates interleukin-8 secretion in human bronchial epithelial cells
    • Cummings, R.J., Parinandi, N.L., Zaiman, A., Wang, L., Usatyuk, P.V., Garcia, J.G. and Natarajan, V. (2002) Phospholipase D activation by sphingosine 1-phosphate regulates interleukin-8 secretion in human bronchial epithelial cells. J. Biol. Chem., 277, 30227-30235.
    • (2002) J. Biol. Chem , vol.277 , pp. 30227-30235
    • Cummings, R.J.1    Parinandi, N.L.2    Zaiman, A.3    Wang, L.4    Usatyuk, P.V.5    Garcia, J.G.6    Natarajan, V.7
  • 38
    • 0014779155 scopus 로고
    • Two dimensional thin layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots
    • Rouser, G., Fleischer, S. and Yamamoto, A. (1969) Two dimensional thin layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots. Lipids, 5, 494-496.
    • (1969) Lipids , vol.5 , pp. 494-496
    • Rouser, G.1    Fleischer, S.2    Yamamoto, A.3
  • 40
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during assembly of the head of bacteriophage T4
    • Laemmli, U.K. (1970) Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature, 227, 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 41
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin, H., Staehelin, T. and Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Natl. Acad. Sci. USA, 76, 4350-4354.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.