Ester prodrugs of morphine improve transdermal drug delivery: A mechanistic study

Journal of Pharmacy and Pharmacology

Volumn 59, Issue 7, 2007, Pages 917-925

  Wang, Jhi Joung ^a   Sung, K C ^b   Huang, Jeng Fen ^b   Yeh, Chih Hui ^c   Fang, Jia You ^c  

^a CHI MEI MEDICAL CENTER   (Taiwan)

^b CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

^c CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ESTER; MORPHINE; MORPHINE ENANTHATE; MORPHINE PROPIONATE; OLEIC ACID; SESAME SEED OIL; TERPINEOL; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROLYSIS; LIPID BILAYER; LIPOPHILICITY; MOUSE; NONHUMAN; PARTITION COEFFICIENT; PH; SKIN PENETRATION; STRATUM CORNEUM;

ADMINISTRATION, CUTANEOUS; ANALGESICS, OPIOID; ANIMALS; CYCLOHEXENES; DRUG DELIVERY SYSTEMS; DRUG STABILITY; ESTERS; HEPTANOATES; HYDROLYSIS; MICE; MICE, NUDE; MONOTERPENES; MORPHINE DERIVATIVES; OLEIC ACID; PERMEABILITY; PRODRUGS; PROPIONATES; SKIN; SKIN ABSORPTION;

EID: 34447295359     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.59.7.0002     Document Type: Article

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