-
1
-
-
0345872083
-
Multidisciplinary management of lung cancer
-
Spira A and Ettinger DS: Multidisciplinary management of lung cancer. N Engl J Med 350: 379-392, 2004.
-
(2004)
N Engl J Med
, vol.350
, pp. 379-392
-
-
Spira, A.1
Ettinger, D.S.2
-
2
-
-
1242273870
-
Improvement Strategies for Molecular Targeting: Cyclooxygenase-2 Inhibitors as Radiosensitizers for Non-Small Cell Lung Cancer
-
DOI 10.1053/j.seminoncol.2003.11.002
-
Komaki R, Liao Z and Milas L: Improvement strategies for molecular targeting: cyclooxygenase-2 inhibitors as radiosensitizers for non-small cell lung cancer. Semin Oncol 31: 47-53, 2004. (Pubitemid 38241020)
-
(2004)
Seminars in Oncology
, vol.31
, Issue.1 SUPPL. 1
, pp. 47-53
-
-
Komaki, R.1
Liao, Z.2
Milas, L.3
-
3
-
-
0037096812
-
Novel targets for lung cancer therapy: Part I
-
DOI 10.1200/JCO.2002.11.145
-
Dy GK and Adjei AA: Novel targets for lung cancer therapy: part I. J Clin Oncol 20: 2881-2894, 2002. (Pubitemid 34651518)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.12
, pp. 2881-2894
-
-
Dy, G.K.1
Adjei, A.A.2
-
5
-
-
0344121661
-
Gene expression changes in mouse brain after exposure to low-dose ionizing radiation
-
DOI 10.1080/09553000310001610961
-
Yin E, Nelson DO, Coleman MA, Peterson LE and Wyrobek AJ: Gene expression changes in mouse brain after exposure to low-dose ionizing radiation. Int J Radiat Biol 79: 759-775, 2003. (Pubitemid 37468143)
-
(2003)
International Journal of Radiation Biology
, vol.79
, Issue.10
, pp. 759-775
-
-
Yin, E.1
Nelson, D.O.2
Coleman, M.A.3
Peterson, L.E.4
Wyrobek, A.J.5
-
6
-
-
0033865240
-
Prediction of tumor response to therapy: Molecular markers and the microenvironment. Apoptosis and chips: An overview of the proceedings
-
Lehnert S: Prediction of tumor response to therapy: molecular markers and the microenvironment. Apoptosis and chips: an overview of the proceedings. Radiat Res 154: 121-124, 2000.
-
(2000)
Radiat Res
, vol.154
, pp. 121-124
-
-
Lehnert, S.1
-
7
-
-
0037379216
-
Manganese superoxide dismutase-mediated gene expression in radiation-induced adaptive responses
-
Guo G, Yan-Sanders Y, Lyn-Cook BD, Wang T, Tamae D, Ogi J, Khaletskiy A, Li Z, Weydert C, Longmate JA, Huang TT, Spitz DR, Oberley LW and Li JJ: Manganese superoxide dismutase-mediated gene expression in radiation-induced adaptive responses. Mol Cell Biol 23: 2362-2378, 2003.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 2362-2378
-
-
Guo, G.1
Yan-Sanders, Y.2
Lyn-Cook, B.D.3
Wang, T.4
Tamae, D.5
Ogi, J.6
Khaletskiy, A.7
Li, Z.8
Weydert, C.9
Longmate, J.A.10
Huang, T.T.11
Spitz, D.R.12
Oberley, L.W.13
Li, J.J.14
-
8
-
-
1642453823
-
p53 activation in chronic radiation-treated breast cancer cells: Regulation of MDM2/p14ARF
-
Xia L, Paik A and Li JJ: p53 activation in chronic radiation-treated breast cancer cells: regulation of MDM2/p14ARF. Cancer Res 64: 221-228, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 221-228
-
-
Xia, L.1
Paik, A.2
Li, J.J.3
-
9
-
-
21244460339
-
Identification of differentially expressed genes contributing to radioresistance in lung cancer cells using microarray analysis
-
DOI 10.1667/RR3401
-
Guo WF, Lin RX, Huang J, Zhou Z, Yang J, Guo GZ and Wang SQ: Identification of differentially expressed genes contributing to radioresistance in lung cancer cells using microarray analysis. Radiat Res 164: 27-35, 2005. (Pubitemid 40885227)
-
(2005)
Radiation Research
, vol.164
, Issue.1
, pp. 27-35
-
-
Guo, W.-F.1
Lin, R.-X.2
Huang, J.3
Zhou, Z.4
Yang, J.5
Guo, G.-Z.6
Wang, S.-Q.7
-
10
-
-
0842304150
-
Mdm2 in the response to radiation
-
Perry ME: Mdm2 in the response to radiation. Mol Cancer Res 2: 9-19, 2004.
-
(2004)
Mol Cancer Res
, vol.2
, pp. 9-19
-
-
Perry, M.E.1
-
12
-
-
0345824731
-
P53-independent functions of MDM2
-
Ganguli G and Wasylyk B: p53-independent functions of MDM2. Mol Cancer Res 1: 1027-1035, 2003.
-
(2003)
Mol Cancer Res
, vol.1
, pp. 1027-1035
-
-
Ganguli, G.1
Wasylyk, B.2
-
13
-
-
0026740449
-
Amplification of a gene encoding a p53-associated protein in human sarcomas
-
Oliner JD, Kinzler KW, Meltzer PS, George DL and Vogelstein B: Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature 358: 80-83, 1992.
-
(1992)
Nature
, vol.358
, pp. 80-83
-
-
Oliner, J.D.1
Kinzler, K.W.2
Meltzer, P.S.3
George, D.L.4
Vogelstein, B.5
-
14
-
-
0028098165
-
Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas
-
Cordon-Cardo C, Latres E, Drobnjak M, Oliva MR, Pollack D, Woodruff JM, Marechal V, Chen J, Brennan MF and Levine AJ: Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas. Cancer Res 54: 794-799, 1994. (Pubitemid 24068339)
-
(1994)
Cancer Research
, vol.54
, Issue.3
, pp. 794-799
-
-
Cordon-Cardo, C.1
Latres, E.2
Drobnjak, M.3
Oliva, M.R.4
Pollack, D.5
Woodruff, J.M.6
Marechal, V.7
Chen, J.8
Brennan, M.F.9
Levine, A.J.10
-
15
-
-
0031740916
-
Alterations of the p16-pRb pathway and the chromosome locus 9p21-22 in non-small-cell lung carcinomas: Relationship with p53 and MDM2 protein expression
-
Gorgoulis VG, Zacharatos P, Kotsinas A, Liloglou T, Kyroudi A, Veslemes M, Rassidakis A, Halazonetis TD, Field JK and Kittas C: Alterations of the p16-pRb pathway and the chromosome locus 9p21-22 in non-small-cell lung carcinomas: relationship with p53 and MDM2 protein expression. Am J Pathol 153: 1749-1765, 1998.
-
(1998)
Am J Pathol
, vol.153
, pp. 1749-1765
-
-
Gorgoulis, V.G.1
Zacharatos, P.2
Kotsinas, A.3
Liloglou, T.4
Kyroudi, A.5
Veslemes, M.6
Rassidakis, A.7
Halazonetis, T.D.8
Field, J.K.9
Kittas, C.10
-
16
-
-
0030877712
-
Immunohistochemical expression of p53, bcl-2, mdm2 and waf1/p21 proteins in colorectal adenocarcinomas
-
Valassiadou KE, Stefanaki K, Tzardi M, Datseris G, Georgoulias V, Melissas J, Tsiftsis DD, Delides G and Kanavaros P: Immunohistochemical expression of p53, bcl-2, mdm2 and waf1/p21 proteins in colorectal adenocarcinomas. Anticancer Res 17: 2571-2576, 1997.
-
(1997)
Anticancer Res
, vol.17
, pp. 2571-2576
-
-
Valassiadou, K.E.1
Stefanaki, K.2
Tzardi, M.3
Datseris, G.4
Georgoulias, V.5
Melissas, J.6
Tsiftsis, D.D.7
Delides, G.8
Kanavaros, P.9
-
17
-
-
0343517136
-
Predictive value of p53, mdm-2, p21, and mib-1 for chemotherapy response in advanced breast cancer
-
Sjostrom J, Blomqvist C, Heikkila P, Boguslawski KV, Raisanen-Sokolowski A, Bengtsson NO, Mjaaland I, Malmstrom P, Ostenstadt B, Bergh J, Wist E, Valvere V and Saksela E: Predictive value of p53, mdm-2, p21, and mib-1 for chemotherapy response in advanced breast cancer. Clin Cancer Res 6: 3103-3110, 2000.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 3103-3110
-
-
Sjostrom, J.1
Blomqvist, C.2
Heikkila, P.3
Boguslawski, K.V.4
Raisanen-Sokolowski, A.5
Bengtsson, N.O.6
Mjaaland, I.7
Malmstrom, P.8
Ostenstadt, B.9
Bergh, J.10
Wist, E.11
Valvere, V.12
Saksela, E.13
-
18
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
DOI 10.1038/35078107
-
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K and Tuschl T: Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411: 494-498, 2001. (Pubitemid 32494397)
-
(2001)
Nature
, vol.411
, Issue.6836
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
19
-
-
0036727416
-
Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
-
Lewis DL, Hagstrom JE, Loomis AG, Wolff JA and Herweijer H: Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat Genet 32: 107-108, 2002.
-
(2002)
Nat Genet
, vol.32
, pp. 107-108
-
-
Lewis, D.L.1
Hagstrom, J.E.2
Loomis, A.G.3
Wolff, J.A.4
Herweijer, H.5
-
20
-
-
0142240170
-
Anti-erbB receptor strategy as a gene therapeutic intervention to improve radiotherapy in malignant human tumours
-
DOI 10.1080/0955300031000102632
-
Lammering G, Hewit TH, Valerie K, Lin PS, Contessa JN and Schmidt-Ullrich RK: Anti-erbB receptor strategy as a gene therapeutic intervention to improve radiotherapy in malignant human tumours. Int J Radiat Biol 79: 561-568, 2003. (Pubitemid 37311061)
-
(2003)
International Journal of Radiation Biology
, vol.79
, Issue.7
, pp. 561-568
-
-
Lammering, G.1
Hewit, T.H.2
Valerie, K.3
Lin, P.S.4
Contessa, J.N.5
Schmidt-Ullrich, R.K.6
-
21
-
-
0026768458
-
Gene therapy for cancer
-
Rosenberg SA: Gene therapy for cancer. JAMA 268: 2416-2419, 1992.
-
(1992)
JAMA
, vol.268
, pp. 2416-2419
-
-
Rosenberg, S.A.1
-
23
-
-
14744278462
-
Small molecule antagonists of the MDM2 oncoprotein as anticancer agents
-
DOI 10.2174/1568009053332672
-
Buolamwini JK, Addo J, Kamath S, Patil S, Mason D and Ores M: Small molecule antagonists of the MDM2 oncoprotein as anticancer agents. Curr Cancer Drug Targets 5: 57-68, 2005. (Pubitemid 40326247)
-
(2005)
Current Cancer Drug Targets
, vol.5
, Issue.1
, pp. 57-68
-
-
Buolamwini, J.K.1
Addo, J.2
Kamath, S.3
Patil, S.4
Mason, D.5
Ores, M.6
-
25
-
-
25444433114
-
MDM2 as a critical effector of the MYCN oncogene in tumorigenesis
-
Slack A and Shohet JM: MDM2 as a critical effector of the MYCN oncogene in tumorigenesis. Cell Cycle 4: 857-860, 2005. (Pubitemid 41359744)
-
(2005)
Cell Cycle
, vol.4
, Issue.7
, pp. 857-860
-
-
Slack, A.1
Shohet, J.M.2
-
26
-
-
0029020147
-
Amplification of the MDM2 gene in human breast cancer and its association with MDM2 and p53 protein status
-
McCann AH, Kirley A, Carney DN, Corbally N, Magee HM, Keating G and Dervan PA: Amplification of the MDM2 gene in human breast cancer and its association with MDM2 and p53 protein status. Br J Cancer 71: 981-985, 1995.
-
(1995)
Br J Cancer
, vol.71
, pp. 981-985
-
-
McCann, A.H.1
Kirley, A.2
Carney, D.N.3
Corbally, N.4
Magee, H.M.5
Keating, G.6
Dervan, P.A.7
-
27
-
-
0028983308
-
Mdm2 gene alterations and mdm2 protein expression in breast carcinomas
-
Marchetti A, Buttitta F, Girlando S, Dalla Palma P, Pellegrini S, Fina P, Doglioni C, Bevilacqua G and Barbareschi M: mdm2 gene alterations and mdm2 protein expression in breast carcinomas. J Pathol 175: 31-38, 1995.
-
(1995)
J Pathol
, vol.175
, pp. 31-38
-
-
Marchetti, A.1
Buttitta, F.2
Girlando, S.3
Dalla Palma, P.4
Pellegrini, S.5
Fina, P.6
Doglioni, C.7
Bevilacqua, G.8
Barbareschi, M.9
-
28
-
-
10744230829
-
MDM2 gene amplification: A new independent factor of adverse prognosis in non-small cell lung cancer (NSCLC)
-
Dworakowska D, Jassem E, Jassem J, Peters B, Dziadziuszko R, Zylicz M, Jakobkiewicz-Banecka J, Kobierska-Gulida G, Szymanowska A, Skokowski J, Roessner A and Schneider-Stock R: MDM2 gene amplification: a new independent factor of adverse prognosis in non-small cell lung cancer (NSCLC). Lung Cancer 43: 285-295, 2004.
-
(2004)
Lung Cancer
, vol.43
, pp. 285-295
-
-
Dworakowska, D.1
Jassem, E.2
Jassem, J.3
Peters, B.4
Dziadziuszko, R.5
Zylicz, M.6
Jakobkiewicz-Banecka, J.7
Kobierska-Gulida, G.8
Szymanowska, A.9
Skokowski, J.10
Roessner, A.11
Schneider-Stock, R.12
-
29
-
-
1042266626
-
An alternative splice form of Mdm2 induces p53-independent cell growth and tumorigenesis
-
Steinman HA, Burstein E, Lengner C, Gosselin J, Pihan G, Duckett CS and Jones SN: An alternative splice form of Mdm2 induces p53-independent cell growth and tumorigenesis. J Biol Chem 279: 4877-4886, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 4877-4886
-
-
Steinman, H.A.1
Burstein, E.2
Lengner, C.3
Gosselin, J.4
Pihan, G.5
Duckett, C.S.6
Jones, S.N.7
-
31
-
-
0037317840
-
Inhibiting the p53-MDM2 interaction: An important target for cancer therapy
-
Chene P: Inhibiting the p53-MDM2 interaction: an important target for cancer therapy. Nat Rev Cancer 3: 102-109, 2003.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 102-109
-
-
Chene, P.1
-
32
-
-
0942268147
-
Antisense MDM2 sensitizes prostate cancer cells to androgen deprivation, radiation, and the combination
-
DOI 10.1016/j.ijrobp.2003.09.029
-
Mu Z, Hachem P, Agrawal S and Pollack A: Antisense MDM2 sensitizes prostate cancer cells to androgen deprivation, radiation, and the combination. Int J Radiat Oncol Biol Phys 58: 336-343, 2004. (Pubitemid 38142457)
-
(2004)
International Journal of Radiation Oncology Biology Physics
, vol.58
, Issue.2
, pp. 336-343
-
-
Mu, Z.1
Hachem, P.2
Agrawal, S.3
Pollack, A.4
-
33
-
-
0034097572
-
Enhancement of drug-induced apoptosis by antisense oligodeoxynucleotides targeted against Mdm2 and p21WAF1/CIP1
-
Sato N, Mizumoto K, Maehara N, Kusumoto M, Nishio S, Urashima T, Ogawa T and Tanaka M: Enhancement of drug-induced apoptosis by antisense oligodeoxynucleotides targeted against Mdm2 and p21WAF1/CIP1. Anticancer Res 20: 837-842, 2000.
-
(2000)
Anticancer Res
, vol.20
, pp. 837-842
-
-
Sato, N.1
Mizumoto, K.2
Maehara, N.3
Kusumoto, M.4
Nishio, S.5
Urashima, T.6
Ogawa, T.7
Tanaka, M.8
-
34
-
-
0037213559
-
Mammalian RNAi for the masses
-
Shi Y: Mammalian RNAi for the masses. Trends Genet 19: 9-12, 2003.
-
(2003)
Trends Genet
, vol.19
, pp. 9-12
-
-
Shi, Y.1
-
35
-
-
17244367104
-
RNAi, a new therapeutic strategy against viral infection
-
DOI 10.1038/sj.cr.7290248, PII 7290248
-
Tan FL and Yin JQ: RNAi, a new therapeutic strategy against viral infection. Cell Res 14: 460-466, 2004. (Pubitemid 43231790)
-
(2004)
Cell Research
, vol.14
, Issue.6
, pp. 460-466
-
-
Tan, F.L.1
Yin, J.Q.2
-
36
-
-
0037382008
-
Enhanced radiation and chemotherapy-mediated cell killing of human cancer cells by small inhibitory RNA silencing of DNA repair factors
-
Collis SJ, Swartz MJ, Nelson WG and De Weese TL: Enhanced radiation and chemotherapy-mediated cell killing of human cancer cells by small inhibitory RNA silencing of DNA repair factors. Cancer Res 63: 1550-1554, 2003.
-
(2003)
Cancer Res
, vol.63
, pp. 1550-1554
-
-
Collis, S.J.1
Swartz, M.J.2
Nelson, W.G.3
De Weese, T.L.4
-
37
-
-
0037380839
-
Small interfering RNA-induced suppression of MDR1 (P-glycoprotein) restores sensitivity to multidrug-resistant cancer cells
-
Wu H, Hait WN and Yang JM: Small interfering RNA-induced suppression of MDR1 (P-glycoprotein) restores sensitivity to multidrug-resistant cancer cells. Cancer Res 63: 1515-1519, 2003. (Pubitemid 36373637)
-
(2003)
Cancer Research
, vol.63
, Issue.7
, pp. 1515-1519
-
-
Wu, H.1
Hait, W.N.2
Yang, J.-M.3
-
38
-
-
0031954535
-
Simultaneous evaluation of radiation-induced apoptosis and micronuclei in five cell lines
-
DOI 10.1080/095530098142392
-
Guo GZ, Sasai K, Oya N, Takagi T, Shibuya K and Hiraoka M: Simultaneous evaluation of radiation-induced apoptosis and micronuclei in five cell lines. Int J Radiat Biol 73: 297-302, 1998. (Pubitemid 28160916)
-
(1998)
International Journal of Radiation Biology
, vol.73
, Issue.3
, pp. 297-302
-
-
Guo, G.Z.1
Sasai, K.2
Oya, N.3
Takagi, T.4
Shibuya, K.5
Hiraoka, M.6
-
39
-
-
0032770644
-
A significant correlation between clonogenic radiosensitivity and the simultaneous assessment of micronucleus and apoptotic cell frequencies
-
DOI 10.1080/095530099139917
-
Guo GZ, Sasai K, Oya N, Shibata T, Shibuya K and Hiraoka MA: Significant correlation between clonogenic radiosensitivity and the simultaneous assessment of micronucleus and apoptotic cell frequencies. Int J Radiat Biol 75: 857-864, 1999. (Pubitemid 29336562)
-
(1999)
International Journal of Radiation Biology
, vol.75
, Issue.7
, pp. 857-864
-
-
Guo, G.Z.1
Sasai, K.2
Oya, N.3
Shibata, T.4
Shibuya, K.5
Hiraoka, M.6
-
40
-
-
28144451956
-
Downregulation of MDM2 expression by RNAi inhibits LoVo human colorectal adenocarcinoma cells growth and the treatment of LoVo cells with mdm2siRNA3 enhances the sensitivity to cisplatin
-
Yu Y, Sun P, Sun LC, Liu GY, Chen GH, Shang LH, Wu HB, Hu J, Li Y, Mao YL, Sui GJ and Sun XW: Downregulation of MDM2 expression by RNAi inhibits LoVo human colorectal adenocarcinoma cells growth and the treatment of LoVo cells with mdm2siRNA3 enhances the sensitivity to cisplatin. Biochem Biophys Res Commun 339: 71-78, 2006.
-
(2006)
Biochem Biophys Res Commun
, vol.339
, pp. 71-78
-
-
Yu, Y.1
Sun, P.2
Sun, L.C.3
Liu, G.Y.4
Chen, G.H.5
Shang, L.H.6
Wu, H.B.7
Hu, J.8
Li, Y.9
Mao, Y.L.10
Sui, G.J.11
Sun, X.W.12
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