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Volumn 153, Issue 6, 1998, Pages 1749-1765

Alterations of the p16-pRb pathway and the chromosome locus 9p21-22 in non-small-cell lung carcinomas: Relationship with p53 and MDM2 protein expression

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE; MICROSATELLITE DNA; PROTEIN P53; RETINOBLASTOMA PROTEIN;

EID: 0031740916     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)65690-8     Document Type: Article
Times cited : (104)

References (90)
  • 1
    • 0002500759 scopus 로고
    • Pathology of lung cancer: An exercise in classification
    • Edited by Johnson BE, Johnson DH. New York, Wiley-Liss
    • Linnoila RI, Aisner SC: Pathology of lung cancer: an exercise in classification. Lung Cancer. Edited by Johnson BE, Johnson DH. New York, Wiley-Liss, 1995, pp 73-95
    • (1995) Lung Cancer , pp. 73-95
    • Linnoila, R.I.1    Aisner, S.C.2
  • 2
    • 0028991396 scopus 로고
    • Mutations of cell cycle regulators
    • Cordon-Cardo C: Mutations of cell cycle regulators. Am J Pathol 1995, 147:545-560
    • (1995) Am J Pathol , vol.147 , pp. 545-560
    • Cordon-Cardo, C.1
  • 3
    • 0030778842 scopus 로고    scopus 로고
    • ARF
    • ARF. Cell 1997, 91:551-558
    • (1997) Cell , vol.91 , pp. 551-558
    • Haber, D.A.1
  • 4
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M, Hannon G, Beach D: A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature 1993, 366:704-707
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.2    Beach, D.3
  • 6
    • 0027504088 scopus 로고
    • Antioncogenes and human cancer
    • Knudson AG: Antioncogenes and human cancer. Proc Natl Acad Sci USA 1993, 90:10914-10921
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10914-10921
    • Knudson, A.G.1
  • 7
    • 0028275733 scopus 로고
    • Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
    • Nobori T, Miura K, Wu DJ, Lois A, Takabayashi K, Carson DA: Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature 1994, 368:753-756
    • (1994) Nature , vol.368 , pp. 753-756
    • Nobori, T.1    Miura, K.2    Wu, D.J.3    Lois, A.4    Takabayashi, K.5    Carson, D.A.6
  • 8
    • 0028033422 scopus 로고
    • Rates of the p16 (MTS1) mutations in primary tumours with 9p loss
    • Cairns P, Mao L, Merlo A: Rates of the p16 (MTS1) mutations in primary tumours with 9p loss. Science 1994, 265:415-416
    • (1994) Science , vol.265 , pp. 415-416
    • Cairns, P.1    Mao, L.2    Merlo, A.3
  • 15
    • 0028879664 scopus 로고
    • Loss of heterozygosity at 9p21 loci and mutations of the MTS1 and MTS2 genes in human lung cancers
    • Shimizu T, Sekiya T: Loss of heterozygosity at 9p21 loci and mutations of the MTS1 and MTS2 genes in human lung cancers. Int J Cancer 1995, 63:616-620
    • (1995) Int J Cancer , vol.63 , pp. 616-620
    • Shimizu, T.1    Sekiya, T.2
  • 16
    • 0029032228 scopus 로고
    • Codeletion of p15 and p16 genes in primary non-small cell lung carcinoma
    • Xiao S, Joseph DL, Vijg J, Fletcher JA: Codeletion of p15 and p16 genes in primary non-small cell lung carcinoma. Cancer Res 1995, 55:2968-2971
    • (1995) Cancer Res , vol.55 , pp. 2968-2971
    • Xiao, S.1    Joseph, D.L.2    Vijg, J.3    Fletcher, J.A.4
  • 17
    • 0028955673 scopus 로고
    • In vivo occurrence of p16 (MTS1) and p15 (MTS2) alterations preferentially in non-small cell lung cancers
    • Washimi O, Nagatake M, Osada H, Ueda R, Koshikawa T, Seki T, Takahashi T: In vivo occurrence of p16 (MTS1) and p15 (MTS2) alterations preferentially in non-small cell lung cancers. Cancer Res 1995, 55:514-517
    • (1995) Cancer Res , vol.55 , pp. 514-517
    • Washimi, O.1    Nagatake, M.2    Osada, H.3    Ueda, R.4    Koshikawa, T.5    Seki, T.6    Takahashi, T.7
  • 26
    • 0029011539 scopus 로고
    • 5′ CpG island methylation is associated with transcriptional silencing of the tumor suppressor p16/CDKN2/MTS1 in human cancers
    • Merlo A, Herman JG, Mao L, Lee DJ, Gabrielson E, Burger PC, Baylin SB, Sydranski D: 5′ CpG island methylation is associated with transcriptional silencing of the tumor suppressor p16/CDKN2/MTS1 in human cancers. Nature Med 1995, 1:686-692
    • (1995) Nature Med , vol.1 , pp. 686-692
    • Merlo, A.1    Herman, J.G.2    Mao, L.3    Lee, D.J.4    Gabrielson, E.5    Burger, P.C.6    Baylin, S.B.7    Sydranski, D.8
  • 27
    • 0028124690 scopus 로고
    • Aberrant Rb gene expression in routinely processed, archival tumor tissues determined by three different anti-Rb antibodies
    • Geradts J, Hu S-X, Lincoln CE, Benedict WF, Xu H-J: Aberrant Rb gene expression in routinely processed, archival tumor tissues determined by three different anti-Rb antibodies. Int J Cancer 1994, 58:161-167
    • (1994) Int J Cancer , vol.58 , pp. 161-167
    • Geradts, J.1    Hu, S.-X.2    Lincoln, C.E.3    Benedict, W.F.4    Xu, H.-J.5
  • 28
    • 0027987001 scopus 로고
    • Retinoblastoma protein expression in lung cancer: An immunohistochemical analysis
    • Higashiyama M, Doi O, Kodama K, Yochouchi H, Tateishi R: Retinoblastoma protein expression in lung cancer: an immunohistochemical analysis. Oncology 1994, 51:544-551
    • (1994) Oncology , vol.51 , pp. 544-551
    • Higashiyama, M.1    Doi, O.2    Kodama, K.3    Yochouchi, H.4    Tateishi, R.5
  • 30
    • 0025899109 scopus 로고
    • Absence of retinoblastoma protein expression in primary non-small cell lung carcinomas
    • Xu H-L, Hu S-X, Cagle PT, Moore GE, Benedict WF: Absence of retinoblastoma protein expression in primary non-small cell lung carcinomas. Cancer Res 1991, 51:2735-2739
    • (1991) Cancer Res , vol.51 , pp. 2735-2739
    • Xu, H.-L.1    Hu, S.-X.2    Cagle, P.T.3    Moore, G.E.4    Benedict, W.F.5
  • 31
    • 0026752654 scopus 로고
    • Negative regulation of Rb expression by the p53 gene product
    • Shiio Y, Yamamoto T, Yamaguchi N: Negative regulation of Rb expression by the p53 gene product. Proc Natl Acad Sci USA 1992, 89:5206-5210
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5206-5210
    • Shiio, Y.1    Yamamoto, T.2    Yamaguchi, N.3
  • 33
    • 0030800922 scopus 로고    scopus 로고
    • Mdm2: Keeping p53 under control
    • Piette J, Neel H, Marechal V. Mdm2: keeping p53 under control. Oncogene 1997, 15:1001-1010
    • (1997) Oncogene , vol.15 , pp. 1001-1010
    • Piette, J.1    Neel, H.2    Marechal, V.3
  • 34
    • 0030777230 scopus 로고    scopus 로고
    • The mdm2 proto-oncogene
    • Haines DS. The mdm2 proto-oncogene. Leuk Lymphoma 1996, 26: 227-238
    • (1996) Leuk Lymphoma , vol.26 , pp. 227-238
    • Haines, D.S.1
  • 36
  • 39
    • 0020070666 scopus 로고
    • The World Health Organization histologic typing of lung tumours
    • World Health Organization: The World Health Organization histologic typing of lung tumours. Am J Clin Pathol 1982, 77:123-136
    • (1982) Am J Clin Pathol , vol.77 , pp. 123-136
  • 40
    • 0029901708 scopus 로고    scopus 로고
    • High frequency of aberrant p16ink4A expression in human breast cancer
    • Geradts J, Wilson PA: High frequency of aberrant p16ink4A expression in human breast cancer. Am J Pathol 1996, 149:15-20
    • (1996) Am J Pathol , vol.149 , pp. 15-20
    • Geradts, J.1    Wilson, P.A.2
  • 41
    • 0013512365 scopus 로고
    • Polymerase chain reaction microanalysis of tumors from stained histological slides
    • Whetsell L, Maw G, Nadon N, Ringer D, Schaefer F: Polymerase chain reaction microanalysis of tumors from stained histological slides. Oncogene 1995, 7:581-585
    • (1995) Oncogene , vol.7 , pp. 581-585
    • Whetsell, L.1    Maw, G.2    Nadon, N.3    Ringer, D.4    Schaefer, F.5
  • 43
    • 0028909163 scopus 로고
    • Microsatellite instability and other molecular abnormalities in non-small cell lung cancer
    • Fong KM, Zimmermann PV, Smith PJ: Microsatellite instability and other molecular abnormalities in non-small cell lung cancer. Cancer Res 1995, 55:28-30
    • (1995) Cancer Res , vol.55 , pp. 28-30
    • Fong, K.M.1    Zimmermann, P.V.2    Smith, P.J.3
  • 45
    • 0029046163 scopus 로고
    • Molecular analysis of p53 gene in laryngeal pre-malignant and malignant lesions: p53 protein immunohistochemical expression is positively related to proliferating cell nuclear antigen labelling index
    • Gorgoulis V, Zoumpourlis V, Rassidakis G, Karameris A, Barbatis C, Spandidos DA, Kittas C: Molecular analysis of p53 gene in laryngeal pre-malignant and malignant lesions: p53 protein immunohistochemical expression is positively related to proliferating cell nuclear antigen labelling index. Virchows Arch 1995, 426:339-344
    • (1995) Virchows Arch , vol.426 , pp. 339-344
    • Gorgoulis, V.1    Zoumpourlis, V.2    Rassidakis, G.3    Karameris, A.4    Barbatis, C.5    Spandidos, D.A.6    Kittas, C.7
  • 46
    • 0028071555 scopus 로고
    • Mutations in the p53 tumour suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt MS, Bennett WP, Hollstein M, Harris CC: Mutations in the p53 tumour suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 1995, 54:4855-4878
    • (1995) Cancer Res , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 49
    • 0032549711 scopus 로고    scopus 로고
    • ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
    • Zhang Y, Xiong Y, Yarbrourgh WG: ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell 1998, 92:725-734
    • (1998) Cell , vol.92 , pp. 725-734
    • Zhang, Y.1    Xiong, Y.2    Yarbrourgh, W.G.3
  • 50
    • 0028787221 scopus 로고
    • CDKN2 gene silencing in lung cancer by DNA hypermethylation, and kinetics of p16INK4 protein induction by 5-aza 2′ deoxycytidine
    • Otterson GA, Kleif SN, Chen W, Coxon AB, Kaye FJ: CDKN2 gene silencing in lung cancer by DNA hypermethylation, and kinetics of p16INK4 protein induction by 5-aza 2′ deoxycytidine. Oncogene 1995, 11:1211-1216
    • (1995) Oncogene , vol.11 , pp. 1211-1216
    • Otterson, G.A.1    Kleif, S.N.2    Chen, W.3    Coxon, A.B.4    Kaye, F.J.5
  • 51
    • 0030778842 scopus 로고    scopus 로고
    • ARF
    • ARF. Cell 1997, 91:555-558
    • (1997) Cell , vol.91 , pp. 555-558
    • Haber, D.A.1
  • 53
    • 0028865984 scopus 로고
    • Immunohistochemical detection of the cyclin dependent kinase inhibitor 2/multiple suppressor gene 1 (CDKN2/MTS1) product p16ink4A in archival human solid tumors: Correlation with retinoblastoma protein expression
    • Geradts J, Kratzke RA, Niehans GA, Lincoln CE: Immunohistochemical detection of the cyclin dependent kinase inhibitor 2/multiple suppressor gene 1 (CDKN2/MTS1) product p16ink4A in archival human solid tumors: correlation with retinoblastoma protein expression. Cancer Res 1995, 55:6006-6011
    • (1995) Cancer Res , vol.55 , pp. 6006-6011
    • Geradts, J.1    Kratzke, R.A.2    Niehans, G.A.3    Lincoln, C.E.4
  • 55
    • 0025883860 scopus 로고
    • Lack of nuclear RB protein staining in GO/middle G1 cells: Correlation to changes in total RB protein level
    • Xu H-J, Hu S-X, Benedict WF: Lack of nuclear RB protein staining in GO/middle G1 cells: correlation to changes in total RB protein level. Oncogene 1991, 6:1139-1146
    • (1991) Oncogene , vol.6 , pp. 1139-1146
    • Xu, H.-J.1    Hu, S.-X.2    Benedict, W.F.3
  • 58
    • 0027234492 scopus 로고
    • A comparison of the biological activities of wild type and mutant p53
    • Zambetti GP, Levine AJ: A comparison of the biological activities of wild type and mutant p53. FASEB J 1993, 7:855-865
    • (1993) FASEB J , vol.7 , pp. 855-865
    • Zambetti, G.P.1    Levine, A.J.2
  • 60
    • 0028270326 scopus 로고
    • Homozygous deletion on chromosome 9p and loss of heterozygosity on 9p, 6p, and 6q in primary human small cell lung cancer
    • Merlo A, Gabrielson E, Mabry M, Vollmer R, Baylin SB, Sydranski D: Homozygous deletion on chromosome 9p and loss of heterozygosity on 9p, 6p, and 6q in primary human small cell lung cancer. Cancer Res 1994, 54:2322-2326
    • (1994) Cancer Res , vol.54 , pp. 2322-2326
    • Merlo, A.1    Gabrielson, E.2    Mabry, M.3    Vollmer, R.4    Baylin, S.B.5    Sydranski, D.6
  • 61
    • 0029007901 scopus 로고
    • Homozygous deletions at chromosome 9p21 and mutation analysis of p16 and p15 in microdissected primary non-small cell lung cancers
    • Packenham JP, Taylor JA, White CM, Anna CH, Barrett JC, Devereux TR: Homozygous deletions at chromosome 9p21 and mutation analysis of p16 and p15 in microdissected primary non-small cell lung cancers. Clin Cancer Res 1995, 1:687-690
    • (1995) Clin Cancer Res , vol.1 , pp. 687-690
    • Packenham, J.P.1    Taylor, J.A.2    White, C.M.3    Anna, C.H.4    Barrett, J.C.5    Devereux, T.R.6
  • 62
    • 0028879664 scopus 로고
    • Loss of heterozygosity at 9p21 loci and mutations of the MTS1 and MTS2 genes in human lung cancers
    • Shimizu T, Sekiya T: Loss of heterozygosity at 9p21 loci and mutations of the MTS1 and MTS2 genes in human lung cancers. Int J Cancer 1995, 63:616-620
    • (1995) Int J Cancer , vol.63 , pp. 616-620
    • Shimizu, T.1    Sekiya, T.2
  • 63
    • 0030941866 scopus 로고    scopus 로고
    • Frequent loss of heterozygosity in early non-small cell lung cancers at chromosome 9p21 proximal to the CDKN2a gene
    • Mead LJ, Gillespie MT, Hung JY, Rane US, Rayeroux KC, Irving LB, Campbell LJ: Frequent loss of heterozygosity in early non-small cell lung cancers at chromosome 9p21 proximal to the CDKN2a gene. Int J Cancer 1997, 71:213-217
    • (1997) Int J Cancer , vol.71 , pp. 213-217
    • Mead, L.J.1    Gillespie, M.T.2    Hung, J.Y.3    Rane, U.S.4    Rayeroux, K.C.5    Irving, L.B.6    Campbell, L.J.7
  • 65
    • 0029088549 scopus 로고
    • Loss of heterozygosity at 9p23 defines a novel locus in non-small cell cancer
    • Neville EM, Stewart M, Myskow M, Donnelly RJ, Field JK: Loss of heterozygosity at 9p23 defines a novel locus in non-small cell cancer. Oncogene 1995, 11:581-585
    • (1995) Oncogene , vol.11 , pp. 581-585
    • Neville, E.M.1    Stewart, M.2    Myskow, M.3    Donnelly, R.J.4    Field, J.K.5
  • 66
    • 0029052428 scopus 로고
    • Localisation of the human gene encoding the cytoskeletal protein talin to chromosome 9p
    • Gilmore AP, Ohanian V, Spurr NK, Critchley DR: Localisation of the human gene encoding the cytoskeletal protein talin to chromosome 9p. Hum Genet 1995, 96:221-224
    • (1995) Hum Genet , vol.96 , pp. 221-224
    • Gilmore, A.P.1    Ohanian, V.2    Spurr, N.K.3    Critchley, D.R.4
  • 67
    • 0029086272 scopus 로고
    • Down regulation of talin alters cell adhesion and the processing of the α5β1 integrin
    • Albiges-Rizo C, Frachet P, Block MR: Down regulation of talin alters cell adhesion and the processing of the α5β1 integrin. J Cell Sci 1995, 108:3317-3329
    • (1995) J Cell Sci , vol.108 , pp. 3317-3329
    • Albiges-Rizo, C.1    Frachet, P.2    Block, M.R.3
  • 68
    • 0028328372 scopus 로고
    • Colon cancer and DNA repair: Have mismatches met their match?
    • Jiricny J: Colon cancer and DNA repair: have mismatches met their match? Trends Genet 1994, 10:164-168
    • (1994) Trends Genet , vol.10 , pp. 164-168
    • Jiricny, J.1
  • 70
    • 0028284887 scopus 로고
    • Genetic instability of microsatellite sequences in many non-small cell lung carcinomas
    • Shridhar V, Siegfried J, Hunt J, del Mar Alonso M, Smith DI: Genetic instability of microsatellite sequences in many non-small cell lung carcinomas. Cancer Res 1994, 54:2084-2087
    • (1994) Cancer Res , vol.54 , pp. 2084-2087
    • Shridhar, V.1    Siegfried, J.2    Hunt, J.3    Del Mar Alonso, M.4    Smith, D.I.5
  • 71
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • Kinzler KW, Vogelstein B: Lessons from hereditary colorectal cancer. Cell 1996, 87:159-170
    • (1996) Cell , vol.87 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 76
    • 0031561477 scopus 로고    scopus 로고
    • E2F: A nodal point in cell cycle regulation
    • Bernards R: E2F: a nodal point in cell cycle regulation. Biochem Biophys Acta 1997, 1333:M33-M40
    • (1997) Biochem Biophys Acta , vol.1333
    • Bernards, R.1
  • 80
    • 85030340735 scopus 로고    scopus 로고
    • Modulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE): A comparative study between the p53REs of the MDM2, WAF1/Cip1 and Bax genes in lung cancer environment
    • Crete, May 9 to 14
    • Zacharatos P, Gorgoulis V, Kotsinas A, Kanavaros P, Zoumpourlis V, Veslemes M, Halazonetis T, Kittas C: Modulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE): a comparative study between the p53REs of the MDM2, WAF1/Cip1 and Bax genes in lung cancer environment. Abstract presented at the 9th p53 Workshop, Crete, May 9 to 14, 1998
    • (1998) 9th P53 Workshop
    • Zacharatos, P.1    Gorgoulis, V.2    Kotsinas, A.3    Kanavaros, P.4    Zoumpourlis, V.5    Veslemes, M.6    Halazonetis, T.7    Kittas, C.8
  • 81
    • 0029054396 scopus 로고
    • mdm2 gene amplification and overexpression in non-small cell lung carcinoma with accumulation of the p53 protein in the absence of p53 gene mutation
    • Marchetti A, Buttitta F, Pellegrini S, Merlo G, Chella A, Angeletti CA, Bevilacqua G: mdm2 gene amplification and overexpression in non-small cell lung carcinoma with accumulation of the p53 protein in the absence of p53 gene mutation. Diagn Mol Pathol 1995, 4:93-97
    • (1995) Diagn Mol Pathol , vol.4 , pp. 93-97
    • Marchetti, A.1    Buttitta, F.2    Pellegrini, S.3    Merlo, G.4    Chella, A.5    Angeletti, C.A.6    Bevilacqua, G.7
  • 82
    • 0029984820 scopus 로고    scopus 로고
    • Analysis of the proportion of p53 bound to mdm-2 in cells with defined growth characteristics
    • Momand J, Zambetti GP: Analysis of the proportion of p53 bound to mdm-2 in cells with defined growth characteristics. Oncogene 1996, 12:2279-2289
    • (1996) Oncogene , vol.12 , pp. 2279-2289
    • Momand, J.1    Zambetti, G.P.2
  • 83
    • 0030667702 scopus 로고    scopus 로고
    • DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
    • Shieh S-Y, Ikeda M, Taya Y, Prives C: DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 1997, 91:325-334
    • (1997) Cell , vol.91 , pp. 325-334
    • Shieh, S.-Y.1    Ikeda, M.2    Taya, Y.3    Prives, C.4
  • 84
    • 0030905284 scopus 로고    scopus 로고
    • Mdm2 promotes the rapid degradation of p53
    • Haupt Y, Maya R, Kazaz A, Oren M: Mdm2 promotes the rapid degradation of p53. Nature 1997, 387:296-299
    • (1997) Nature , vol.387 , pp. 296-299
    • Haupt, Y.1    Maya, R.2    Kazaz, A.3    Oren, M.4
  • 85
    • 0028087776 scopus 로고
    • p53, guardian of Rb
    • White E: p53, guardian of Rb. Nature 1994, 371:21-22
    • (1994) Nature , vol.371 , pp. 21-22
    • White, E.1
  • 86
    • 0026041836 scopus 로고
    • Aberrations of the tumor suppressor p53 and the retinoblastoma genes in human hepatocellular carcinomas
    • Murakami Y, Hirayashi K, Hirohashi S, Sekiya T: Aberrations of the tumor suppressor p53 and the retinoblastoma genes in human hepatocellular carcinomas. Cancer Res 1991, 51:5520-5525
    • (1991) Cancer Res , vol.51 , pp. 5520-5525
    • Murakami, Y.1    Hirayashi, K.2    Hirohashi, S.3    Sekiya, T.4
  • 87
    • 0025076728 scopus 로고
    • Frequent mutations in the p53 tumor suppressor gene in human leukemia T-cell lines
    • Cheng J, Mass M: Frequent mutations in the p53 tumor suppressor gene in human leukemia T-cell lines. Mol Cell Biol 1990, 10:5502-5509
    • (1990) Mol Cell Biol , vol.10 , pp. 5502-5509
    • Cheng, J.1    Mass, M.2
  • 89
    • 0028288313 scopus 로고
    • Biology of lung cancer
    • Kalemkerian GP: Biology of lung cancer. Curr Opin Oncol 1994, 6:147-155
    • (1994) Curr Opin Oncol , vol.6 , pp. 147-155
    • Kalemkerian, G.P.1


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