A significant correlation between clonogenic radiosensitivity and the simultaneous assessment of micronucleus and apoptotic cell frequencies

International Journal of Radiation Biology

Volumn 75, Issue 7, 1999, Pages 857-864

  Guo, G Z ^a   Sasai, K ^b   Oya, N ^c   Shibata, T ^c   Shibuya, K ^c   Hiraoka, M ^c  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b KYOTO UNIVERSITY   (Japan)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL SURVIVAL; CHO CELL; CLONOGENESIS; HUMAN; HUMAN CELL; IRRADIATION; MICRONUCLEUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIOSENSITIVITY; REGRESSION ANALYSIS; X RAY;

ANIMALS; APOPTOSIS; CELL ADHESION; CELL SURVIVAL; CHO CELLS; CRICETINAE; HUMANS; MICE; MICRONUCLEUS TESTS; MULTIVARIATE ANALYSIS; RADIATION TOLERANCE; REGRESSION ANALYSIS; TUMOR CELLS, CULTURED; TUMOR STEM CELL ASSAY;

ANIMALIA; MAMMALIA;

EID: 0032770644     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/095530099139917     Document Type: Article

References (29)

1. ABEND, M., RHEIN, A., GILBERTZ, K.-P., BLAKELY, W. F. and VAN BEUNINGEN, D., 1995, Correlation of micronucleus and apoptosis assays with reproductive cell death. International Journal of Radiation Biology, 67, 315-326.
2. BUSH, C. and MCMILLAN, T. J., 1993, Micronucleus formation in human tumor cells: lack of correlation with radiosensitivity. British Journal of Cancer, 67, 102-106.
3. DARZYNKIEWICZ, Z., JCAN, G., LI, X., GORCZYCA, W., MURAKAMI, T. and TRAGANOS, F., 1997, Cytometry in cell necrobiology: analysis of apoptosis and accidental cell death (necrosis). Cytometry, 27, 1-20.
4. DEWEY, W. C., LING, C. C. and MEYN, R. E., 1995, Radiation-induced apoptosis: relevance to radiotherapy. International Journal of Radiation Oncology, Biology, Physics, 33, 781-796.
5. GUO, M., CHEN, C., VIDAIR, C., MARINO, S., DEWEY, W. C. and LING, C. C., 1997, Characterization of radiation-induced apoptosis in rodent cell lines. Radiation Research, 147, 295-303.
6. GUO, G. Z., SASAI, K., OYA, N., TAKAGI, T., SHIBUYA, K. and HIRAOKA, M., 1998, Simultaneous evaluation of radiation-induced apoptosis and micronuclei in five cell lines. International Journal of Radiation Biology, 73, 297-302.
7. HARMS-RINGDAHL, M., NICOTERA, P. and RADFORD, I. R., 1996, Radiation induced apoptosis. Mutation Research, 366, 171-179.
8. HENDRY, J. H., POTTEN, C. S. and MERRITT, A., 1995, Apoptosis induced by high- and low-LET radiations. Radiation and Environment Biophysics, 34, 59-62.
9. HENDRY, J. H. and WEST, C. M. L., 1997, Apoptosis und mitotic cell death: their relative contributions to normal-tissue and tumour radiation response. International Journal of Radiation Biology, 71, 709-719.
10. HOEL, P. G., 1984, Empirical methods for correlation and regression. Multiple linear regression. In Introduction to Mathematical Statistics by P. G. Hoel, 5th edition (New York: John Wiley & Sons), pp. 203-206.
11. JAMALI, M. and TROTT, K.-R., 1996, Increased micronucleus frequency in the progeny of irradiated Chinese hamster cells. International Journal of Radiation Biology, 69, 301-307.
12. KlRSCH-VOLDERS, M., ELHAJOUJI, A., CUNDARI, E. and VAN HUMMELEN, P., 1997, The in vitro micronucleus test: a multi-endpoint assay to detect simultaneously mitotic delay, apoptosis, chromosome breakage, chromosome loss and non-disjunction. Mutation Research, 392, 19-30.
13. LEVINE, E. L., RENEHAN, A., GOSSIEL, R., DAVIDSON, S. E., ROBERTS, S. A., CHADWICK, C., WILKS, D. P., POTTEN, C. S., HENDRY, J. H., HUNTER, R. D. and WEST, C. M. L., 1995, Apoptosis, intrinsic radiosensitivity and prediction of radiotherapy response in cervical carcinoma. Radiotherapy and Oncology, 37, 1-9.
14. MARASCUILO, L. A. and SERLIN, R. C., 1988a, The two-sample Wilcoxon Test and the Mann Whitney U test. In Statistical Methods for the Social and Behavioral Sciences by L. A. Marascuilo and R. C. Serlin (New York: W. H. Freeman and Company), pp. 228-244.
15. MARASCUILO, L. A. and SERLIN, R. C., 1988b, Procedures for multiple independent variables. In Statistical Methods for the Social and Behavioral Sciences by L. A. Marascuilo and R. C. Serlin (New York: W. H. Freeman and Company), pp. 637-736.
16. MARIYA, Y., STREFFER, C., FUHRMANN, C. and WOJCIK, A., 1997, Correlation of radiation-induced micronucleus frequency with clonogenic survival in cells of one diploid and two tetraploid murine tumor cell lines of the same origin. Radiation Research, 147, 29-37.
17. MCKENNA, W. G., BERNHARD, E. J., MARKIEWICZ, D. A., RUDOLTZ, M. S., MAITY, A. and MUSCHEL, R. J., 1996, Regulation of radiation-induced apoptosis in oncogene-transfected fibroblasts: influence of H-ras on the G2 delay. Oncogene, 12, 237-245.
18. OLIVE, P. L., BANATH, J. P. and DURAND, R. E., 1996, Development of apoptosis and polyploidy in human lymphoblast cells as a function of position in the cell cycle at the time of irradiation. Radiation Research, 146, 595-602.
19. OLIVE, P. L. and DURAND, R. E., 1997, Apoptosis: an indicator of radiosensitivity in vitro? International Journal of Radiation Biology, 71, 695-707.
20. RADFORD, I. R. and MURPHY, T. K., 1994, Radiation response of mouse lymphoid and myeloid cell lines. Part III. Different signals can lead to apoptosis and may influence sensitivity to killing by DNA double-strand breakage. International Journal of Radiation Biology, 65, 229-239.
21. RADFORD, I. R., MURPHY, T. K., RADLEY, J. M. and ELLIS, S. L., 1994, Radiation response of mouse lymphoid and myeloid cell lines. Part II. Apoptotic death is shown by all lines examined. International Journal of Radiation Biology, 65, 217-227.
22. SASAI, K., EVANS, J. W., KOVACS, M. S. and BROWN, J. M., 1994, Prediction of human cell radiosensitivity: comparison of clonogenic assay with chromosome aberrations scored using premature chromosome condensation with fluorescence in situ hybridization. International Journal Radiation Oncology, Biology, Physics, 30, 1127-1132.
23. SLAVOTINEK, A., MCMILLAN, T. J. and STEEL, C. M., 1993, A comparison of micronucleus frequency and radiation survival in lymphoblastoid cell lines. Mutagenesis, 8, 569-575.
24. TAKAGI, H., 1993, Multiregression analysis. In Multivariate Analysis Handbook (in Japanese), edited by H. Yanai and H. Takagi (Kyoto, Japan: Gendaisuugakusha).
25. VILLA, R., ZAFFARONI, N., GORNATT, D., COSTA, A. and SILVESTRINI, R., 1994, Lack of a correlation between micronucleus formation and radiosensitivity in established and primary cultures of human tumours. British Journal of Cancer, 70, 1112-1117.
26. WANDL, E. O., ONO, K., KAIN, R., HERBSTHOFER, T., HIENERT, G. and HOEBERTH, K., 1989, Linear correlation between surviving fraction and the micronucleus frequency. International Journal of Radiation Biology, 56, 771-775.
27. WEST, C. M. L., 1995, Intrinsic radiosensitivity as a predictor of patient response to radiotherapy. British Journal of Radiology, 68, 827-837.
28. WILKS, D. P., BARRY, J., HUGHES, M. F. and WEST, C. M. L., 1996, Assessment of light scatter by nucleosides as a rapid predictive assay of radiosensitivity. Radiation Research, 146, 628-635.
29. YANAGIHARA, K., NII, M., NUMOTO, M., KAMIYA, K., TAUCHI, H., SAWADA, S. and SEITO, T., 1995, Radiation-induced apoptotic cell death in human gastric epithelial tumour cells; correlation between mitotic death and apoptosis. International Journal of Radiation Biology, 67, 677-685.