-
1
-
-
0030448814
-
Blood vessels formation: What is his molecular basis?
-
Folkman J, D'Amore P. Blood vessels formation: what is his molecular basis? Cell 1996; 87: 1153-5.
-
(1996)
Cell
, vol.87
, pp. 1153-1155
-
-
Folkman, J.1
D'Amore, P.2
-
2
-
-
0030952289
-
Mechanism of angiogenesis
-
Risau W. Mechanism of angiogenesis. Nature 1997; 386: 671-4.
-
(1997)
Nature
, vol.386
, pp. 671-674
-
-
Risau, W.1
-
4
-
-
0026725537
-
Cytokine regulation of endothelial cell function
-
Mantovani A, Bussolino F, Dejana E. Cytokine regulation of endothelial cell function. FASEB J 1992; 6: 2591-9.
-
(1992)
FASEB J
, vol.6
, pp. 2591-2599
-
-
Mantovani, A.1
Bussolino, F.2
Dejana, E.3
-
5
-
-
0034092011
-
Tumor angiogenesis: Past, present and the near future
-
Kerbel RS. Tumor angiogenesis: past, present and the near future. Carcinogenesis 2000; 21: 505-15.
-
(2000)
Carcinogenesis
, vol.21
, pp. 505-515
-
-
Kerbel, R.S.1
-
7
-
-
8944248812
-
Flk-1 as a target for tumor growth inhibition
-
Strawn LM, McMahon G, App H, Schreck R, Kuchler WR, Longhi MP, et al. Flk-1 as a target for tumor growth inhibition. Cancer Res 1996; 56: 3540-5.
-
(1996)
Cancer Res
, vol.56
, pp. 3540-3545
-
-
Strawn, L.M.1
McMahon, G.2
App, H.3
Schreck, R.4
Kuchler, W.R.5
Longhi, M.P.6
-
8
-
-
0034672373
-
Vascular endothelial growth factor-stimulated endothelial cells promote adhesion and activation of platelets
-
Verheul HM, Jorna AS, Hoeckman K, Broxterman HJ, Gebbink MF, Pinedo HM. Vascular endothelial growth factor-stimulated endothelial cells promote adhesion and activation of platelets. Blood 2000; 96: 4216-21.
-
(2000)
Blood
, vol.96
, pp. 4216-4221
-
-
Verheul, H.M.1
Jorna, A.S.2
Hoeckman, K.3
Broxterman, H.J.4
Gebbink, M.F.5
Pinedo, H.M.6
-
9
-
-
0030911308
-
The regulation of neovascularization by matrix metalloproteinases and their inhibitors
-
Moses MA. The regulation of neovascularization by matrix metalloproteinases and their inhibitors. Stem Cells 1997; 15: 180-9.
-
(1997)
Stem Cells
, vol.15
, pp. 180-189
-
-
Moses, M.A.1
-
11
-
-
0035938195
-
Release of pro and anti-angiogenic factors by human cardiac fibroblasts: Effects on DNA synthesis and protection under hypoxia in human endothelial cells
-
Zhao L, Eghbali-Webb M. Release of pro and anti-angiogenic factors by human cardiac fibroblasts: effects on DNA synthesis and protection under hypoxia in human endothelial cells. Bioch Biophys Acta 2002; 1538: 273-82.
-
(2002)
Bioch Biophys Acta
, vol.1538
, pp. 273-282
-
-
Zhao, L.1
Eghbali-Webb, M.2
-
12
-
-
0033057962
-
Mammalian heparanase: Gene cloning, expression and function in tumor progression and metastasis
-
Vlodavsky I, Friedmann I, Elkin M, Aingorn H, Atzmon R, Ishai-Michaeli R, et al. Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis. Nat Med 1999; 5: 793-802.
-
(1999)
Nat Med
, vol.5
, pp. 793-802
-
-
Vlodavsky, I.1
Friedmann, I.2
Elkin, M.3
Aingorn, H.4
Atzmon, R.5
Ishai-Michaeli, R.6
-
13
-
-
0031834239
-
A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF
-
Benjamin LE, Herno I, Keshet E. A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development 1998; 125: 1591-8.
-
(1998)
Development
, vol.125
, pp. 1591-1598
-
-
Benjamin, L.E.1
Herno, I.2
Keshet, E.3
-
14
-
-
0029171892
-
Angiogenesis inhibitors generated by tumors
-
Folkman J. Angiogenesis inhibitors generated by tumors. Mol Med 1995; 1: 120-2.
-
(1995)
Mol Med
, vol.1
, pp. 120-122
-
-
Folkman, J.1
-
15
-
-
0028929803
-
Angiogenesis in cancer, vascular, rheumatoid and other diseases
-
Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other diseases. Nat Med 1995; 1: 27-31.
-
(1995)
Nat Med
, vol.1
, pp. 27-31
-
-
Folkman, J.1
-
16
-
-
0035352721
-
Angiogenesis: Pathological, prognostic, and growth-factor pathways and their link to trial design and anticancer drugs
-
Fox SB, Gasparini G, Harris AL. Angiogenesis: pathological, prognostic, and growth-factor pathways and their link to trial design and anticancer drugs. Lancet Oncol 2001; 2: 278-89.
-
(2001)
Lancet Oncol
, vol.2
, pp. 278-289
-
-
Fox, S.B.1
Gasparini, G.2
Harris, A.L.3
-
17
-
-
0035167615
-
Vascular endothelial growth factor signaling pathways as an emerging target in haematological malignancies
-
List AF. Vascular endothelial growth factor signaling pathways as an emerging target in haematological malignancies. Oncologist 2001; 6: 24-31.
-
(2001)
Oncologist
, vol.6
, pp. 24-31
-
-
List, A.F.1
-
18
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971; 285:1182-6.
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
19
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996; 86: 353-64.
-
(1996)
Cell
, vol.86
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
20
-
-
0034256094
-
Inhibition of tumor angiogenesis by synthetic receptors tyrosine kinase inhibitors
-
Sun L, McMahon G. Inhibition of tumor angiogenesis by synthetic receptors tyrosine kinase inhibitors. Drug Discov Today 2000; 5: 344-53.
-
(2000)
Drug Discov Today
, vol.5
, pp. 344-353
-
-
Sun, L.1
McMahon, G.2
-
21
-
-
22144431918
-
In silico analysis of angiogenesis associated genes expression identifies angiogenic stage related profiles
-
van Beijnum JR, Griffioen AW. In silico analysis of angiogenesis associated genes expression identifies angiogenic stage related profiles. Bioch Biophys Acta 2005; 1755: 121-34.
-
(2005)
Bioch Biophys Acta
, vol.1755
, pp. 121-134
-
-
van Beijnum, J.R.1
Griffioen, A.W.2
-
22
-
-
0032792360
-
The rationale and future potential of angiogenesis inhibitors in neoplasia
-
Gasparrini G. The rationale and future potential of angiogenesis inhibitors in neoplasia. Drugs 1999; 58: 17-38.
-
(1999)
Drugs
, vol.58
, pp. 17-38
-
-
Gasparrini, G.1
-
23
-
-
0034090097
-
Angiogenesis: Potential for pharmacological intervenction in the treatment of cancer, cardiovascular diseases, and chronic inflammation
-
Griffioen AW, Molema G. Angiogenesis: potential for pharmacological intervenction in the treatment of cancer, cardiovascular diseases, and chronic inflammation. Pharmacol Rev 2000; 52: 237-68.
-
(2000)
Pharmacol Rev
, vol.52
, pp. 237-268
-
-
Griffioen, A.W.1
Molema, G.2
-
24
-
-
0036488496
-
Specialization of tumour vasculature
-
Ruoslathi E. Specialization of tumour vasculature. Nat Rev Cancer 2002; 2: 83-90.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 83-90
-
-
Ruoslathi, E.1
-
25
-
-
0001433455
-
Transmission of a malignant new growth by means of a cell-free filtrate
-
Rous PA. Transmission of a malignant new growth by means of a cell-free filtrate. JAMA 1911; 56: 198.
-
(1911)
JAMA
, vol.56
, pp. 198
-
-
Rous, P.A.1
-
26
-
-
0017745268
-
Identification of a transformation-specific antigen induced by an avian sarcoma virus
-
Brugge JS, Erikson RL. Identification of a transformation-specific antigen induced by an avian sarcoma virus. Nature 1977; 269: 346-8.
-
(1977)
Nature
, vol.269
, pp. 346-348
-
-
Brugge, J.S.1
Erikson, R.L.2
-
27
-
-
0017250977
-
DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA
-
Stehelin D, Varmus HE, Bishop JM, Vogt PK. DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA. Nature 1976; 260: 170-3.
-
(1976)
Nature
, vol.260
, pp. 170-173
-
-
Stehelin, D.1
Varmus, H.E.2
Bishop, J.M.3
Vogt, P.K.4
-
28
-
-
0030072570
-
Vertebrate non-receptor protein-tyrosine kinases families
-
Neet K, Hunter T. Vertebrate non-receptor protein-tyrosine kinases families. Genes cells 1996; 1: 147-69.
-
(1996)
Genes cells
, vol.1
, pp. 147-169
-
-
Neet, K.1
Hunter, T.2
-
29
-
-
0027716791
-
The Src family of tyrosine protein kinases in hemopoietic signal transduction
-
Tsygankov AY, Bolen JB. The Src family of tyrosine protein kinases in hemopoietic signal transduction. Stem Cells 1993; 11: 371-80.
-
(1993)
Stem Cells
, vol.11
, pp. 371-380
-
-
Tsygankov, A.Y.1
Bolen, J.B.2
-
30
-
-
17444374230
-
Src kinase regulation by phosphorylation and dephosphorylation
-
Roskosky RJ. Src kinase regulation by phosphorylation and dephosphorylation. Biochem Biophys Res Commun 2005; 331: 1-14.
-
(2005)
Biochem Biophys Res Commun
, vol.331
, pp. 1-14
-
-
Roskosky, R.J.1
-
31
-
-
15544389207
-
Novel insights into c-Src
-
Alper Ö, Bowden ET. Novel insights into c-Src. Curr Pharm Des 2005; 11: 1119-30.
-
(2005)
Curr Pharm Des
, vol.11
, pp. 1119-1130
-
-
Alper, O.1
Bowden, E.T.2
-
32
-
-
0023885305
-
The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains
-
Hanks SK, Quinn AM, Hunter T. The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science 1988; 241: 42-52.
-
(1988)
Science
, vol.241
, pp. 42-52
-
-
Hanks, S.K.1
Quinn, A.M.2
Hunter, T.3
-
33
-
-
0033001789
-
Crystal structures of c-Src reveal features of its autoinhibitory mechanism
-
Xu W, Doshi A, Lei M, Eck MJ, Harrison SC. Crystal structures of c-Src reveal features of its autoinhibitory mechanism. Mol Cell 1999; 3: 629-38.
-
(1999)
Mol Cell
, vol.3
, pp. 629-638
-
-
Xu, W.1
Doshi, A.2
Lei, M.3
Eck, M.J.4
Harrison, S.C.5
-
34
-
-
0033063429
-
Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor
-
Schindler T, Sicheri F, Pico A, Gazit A, Levitzki A, Kuriyan J. Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor. Mol Cell 1999; 3: 639-48.
-
(1999)
Mol Cell
, vol.3
, pp. 639-648
-
-
Schindler, T.1
Sicheri, F.2
Pico, A.3
Gazit, A.4
Levitzki, A.5
Kuriyan, J.6
-
35
-
-
0026341507
-
Phosphorylation of c-Src on tyrosine 527 by another protein tyrosine kinase
-
Thomas JE, Soriano P, Brugge JS. Phosphorylation of c-Src on tyrosine 527 by another protein tyrosine kinase. Science 1991; 254: 568-71.
-
(1991)
Science
, vol.254
, pp. 568-571
-
-
Thomas, J.E.1
Soriano, P.2
Brugge, J.S.3
-
36
-
-
20444399897
-
The crystal structure of a c-Src complex in an active conformation suggests possible steps in c-Src activation
-
Cowan-Jacob SW, Fendrich G, Manley PW, Jahnke W, Fabbro D, Liebetanz J, et al. The crystal structure of a c-Src complex in an active conformation suggests possible steps in c-Src activation. Structures 2005; 13: 861-71.
-
(2005)
Structures
, vol.13
, pp. 861-871
-
-
Cowan-Jacob, S.W.1
Fendrich, G.2
Manley, P.W.3
Jahnke, W.4
Fabbro, D.5
Liebetanz, J.6
-
37
-
-
25144523329
-
Crystal structures of active SRC kinase domain complexes
-
Breitenlechner CB, Kairies NA, Honold K, Scheiblich S, Koll H, Greiter E, et al. Crystal structures of active SRC kinase domain complexes. J Mol Biol 2005; 353: 222-31.
-
(2005)
J Mol Biol
, vol.353
, pp. 222-231
-
-
Breitenlechner, C.B.1
Kairies, N.A.2
Honold, K.3
Scheiblich, S.4
Koll, H.5
Greiter, E.6
-
38
-
-
0029896163
-
Regulation, substrates and functions of src
-
Brown MT, Cooper JA. Regulation, substrates and functions of src. Biochim Biophys Acta 1996; 1287: 121-49.
-
(1996)
Biochim Biophys Acta
, vol.1287
, pp. 121-149
-
-
Brown, M.T.1
Cooper, J.A.2
-
39
-
-
13544256790
-
Src protein-tyrosine kinase structure and regulation
-
Roskoski RJ. Src protein-tyrosine kinase structure and regulation. Biochem Biophys Res Commun 2004; 324: 1155-64.
-
(2004)
Biochem Biophys Res Commun
, vol.324
, pp. 1155-1164
-
-
Roskoski, R.J.1
-
40
-
-
2442623056
-
SRC: Regulation, role in human carcinogenesis and pharmacological inhibitors
-
Tsygankov AY, Shore SK. SRC: regulation, role in human carcinogenesis and pharmacological inhibitors. Curr Pharm Des 2004; 10: 1745-56.
-
(2004)
Curr Pharm Des
, vol.10
, pp. 1745-1756
-
-
Tsygankov, A.Y.1
Shore, S.K.2
-
41
-
-
0026023289
-
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
-
Soriano P, Montgomery C, Geske R, Bradley A. Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell 1991; 64: 693-702.
-
(1991)
Cell
, vol.64
, pp. 693-702
-
-
Soriano, P.1
Montgomery, C.2
Geske, R.3
Bradley, A.4
-
42
-
-
2942662100
-
Basis and importance of Src as a target in cancer
-
Levin VA. Basis and importance of Src as a target in cancer. Cancer Treat Res 2004; 119: 89-119.
-
(2004)
Cancer Treat Res
, vol.119
, pp. 89-119
-
-
Levin, V.A.1
-
43
-
-
0842281489
-
Multiple connections link FAK to cell motility and invasion
-
Schlaepfer DD, Mitra SK. Multiple connections link FAK to cell motility and invasion. Curr Opin Genet Dev 2004; 14: 92-101.
-
(2004)
Curr Opin Genet Dev
, vol.14
, pp. 92-101
-
-
Schlaepfer, D.D.1
Mitra, S.K.2
-
44
-
-
0031438076
-
G protein-coupled receptors mediate two functionally distinct pathways of tyrosine phosphorylation in rat 1a fibroblasts. Shc phosphorylation and receptor endocytosis correlate with activation of Erk kinases
-
Luttrell LM, Daaka Y, Della Rocca GJ, Lefkowitz RJ. G protein-coupled receptors mediate two functionally distinct pathways of tyrosine phosphorylation in rat 1a fibroblasts. Shc phosphorylation and receptor endocytosis correlate with activation of Erk kinases. J Biol Chem 1997; 272: 31648-56.
-
(1997)
J Biol Chem
, vol.272
, pp. 31648-31656
-
-
Luttrell, L.M.1
Daaka, Y.2
Della Rocca, G.J.3
Lefkowitz, R.J.4
-
45
-
-
0033555946
-
Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling
-
Ahn S, Maudsley S, Luttrell MN, Lefkowitz RJ, Daaka Y. Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling. J Biol Chem 1999; 247: 1185-8.
-
(1999)
J Biol Chem
, vol.247
, pp. 1185-1188
-
-
Ahn, S.1
Maudsley, S.2
Luttrell, M.N.3
Lefkowitz, R.J.4
Daaka, Y.5
-
46
-
-
0030473947
-
Association of Src tyrosine kinase with a human potassium channel mediated by SH3 domain
-
Holmes TC, Fadool DA, Ren R, Levitan IB. Association of Src tyrosine kinase with a human potassium channel mediated by SH3 domain. Science 1996; 274: 2089-91.
-
(1996)
Science
, vol.274
, pp. 2089-2091
-
-
Holmes, T.C.1
Fadool, D.A.2
Ren, R.3
Levitan, I.B.4
-
47
-
-
0033575279
-
Phosphorylation and cytoskeletal anchoring of the acetylcholine receptor by Src class protein-tyrosine kinases. Activation by rapsyn
-
Mohamed AS, Swope SL. Phosphorylation and cytoskeletal anchoring of the acetylcholine receptor by Src class protein-tyrosine kinases. Activation by rapsyn. J Biol Chem 1999; 274: 20529-39.
-
(1999)
J Biol Chem
, vol.274
, pp. 20529-20539
-
-
Mohamed, A.S.1
Swope, S.L.2
-
48
-
-
0141538143
-
SRC family kinases: Potential targets for the treatment of human cancer and leukemia
-
Warmuth M, Damoiseaux R, Liu Y, Fabbro D, Gray N. SRC family kinases: potential targets for the treatment of human cancer and leukemia. Curr Pharm Des 2003; 9: 2043-59.
-
(2003)
Curr Pharm Des
, vol.9
, pp. 2043-2059
-
-
Warmuth, M.1
Damoiseaux, R.2
Liu, Y.3
Fabbro, D.4
Gray, N.5
-
49
-
-
0038386613
-
Src family kinases in tumor progression and metastasis
-
Summy JM, Gallick GE. Src family kinases in tumor progression and metastasis. Cancer Metastasis Rev 2003; 22: 337-58.
-
(2003)
Cancer Metastasis Rev
, vol.22
, pp. 337-358
-
-
Summy, J.M.1
Gallick, G.E.2
-
50
-
-
0032932248
-
Activating SRC mutation in a subset of advanced human colon cancers
-
Irby RB, Mao W, Coppola D, Kang J, Loubeau JM, Trudeau W, et al. Activating SRC mutation in a subset of advanced human colon cancers. Nat Genet 1999; 21: 187-90.
-
(1999)
Nat Genet
, vol.21
, pp. 187-190
-
-
Irby, R.B.1
Mao, W.2
Coppola, D.3
Kang, J.4
Loubeau, J.M.5
Trudeau, W.6
-
51
-
-
0037799518
-
Tumor bone diseases: Molecular mechanisms and opportunities for novel treatments
-
Susa M, Glatt M, Teti A. Tumor bone diseases: molecular mechanisms and opportunities for novel treatments. Curr Med Chem Anticancer Agents 2001; 1: 313-29.
-
(2001)
Curr Med Chem Anticancer Agents
, vol.1
, pp. 313-329
-
-
Susa, M.1
Glatt, M.2
Teti, A.3
-
52
-
-
23044500874
-
Tyrosine phosphorylation of paxillin affects the metastatic potential of human osteosarcoma
-
Azuma K, Tanaka M, Uekita T, Inoue S, Yokota J, Ouchi Y, et al. Tyrosine phosphorylation of paxillin affects the metastatic potential of human osteosarcoma. Oncogene 2005; 24: 4754-64.
-
(2005)
Oncogene
, vol.24
, pp. 4754-4764
-
-
Azuma, K.1
Tanaka, M.2
Uekita, T.3
Inoue, S.4
Yokota, J.5
Ouchi, Y.6
-
53
-
-
13244255633
-
Prion-associated increases in Src-family kinases
-
Nixon R.R. Prion-associated increases in Src-family kinases. J Biol Chem 2005; 280: 2455-62.
-
(2005)
J Biol Chem
, vol.280
, pp. 2455-2462
-
-
Nixon, R.R.1
-
54
-
-
0033568033
-
Src kinases involved in hepatitis B virus replication
-
Klein NP, Bouchard MJ, Wang LH, Kobarg C, Schneider RJ. Src kinases involved in hepatitis B virus replication. EMBO J 1999; 18: 5019-27.
-
(1999)
EMBO J
, vol.18
, pp. 5019-5027
-
-
Klein, N.P.1
Bouchard, M.J.2
Wang, L.H.3
Kobarg, C.4
Schneider, R.J.5
-
55
-
-
11144320637
-
Tyrosine kinase inhibitors attenuate Japanese encephalitis virus-induced neurotoxicity
-
Raung S, Chen S, Liao S, Chen J, Chen C. Tyrosine kinase inhibitors attenuate Japanese encephalitis virus-induced neurotoxicity. Biochem Bhiophys Res Comm 2005; 327: 399-406.
-
(2005)
Biochem Bhiophys Res Comm
, vol.327
, pp. 399-406
-
-
Raung, S.1
Chen, S.2
Liao, S.3
Chen, J.4
Chen, C.5
-
56
-
-
0037150728
-
-
Frame M. Src in cancer: deregulation and consequences for cell behaviour. Biochim Biophys Acta 2002; 1602: 114-30.
-
Frame M. Src in cancer: deregulation and consequences for cell behaviour. Biochim Biophys Acta 2002; 1602: 114-30.
-
-
-
-
57
-
-
33644661269
-
Src family kinases as regulators of angiogenesis: Therapeutic implications
-
Lesslie DP III, Gallick GE. Src family kinases as regulators of angiogenesis: therapeutic implications. Curr Cancer Ther Rev 2005; 1: 45-50.
-
(2005)
Curr Cancer Ther Rev
, vol.1
, pp. 45-50
-
-
Lesslie III, D.P.1
Gallick, G.E.2
-
58
-
-
0025336260
-
The embryonic environment strongly attenuates v-Src oncogenesis in mesenchymal and epithelial tissues, but not in endothelia
-
Stoker AW, Hatier C, Bissel MJ. The embryonic environment strongly attenuates v-Src oncogenesis in mesenchymal and epithelial tissues, but not in endothelia. J Cell Biol 1990; 111: 217-28.
-
(1990)
J Cell Biol
, vol.111
, pp. 217-228
-
-
Stoker, A.W.1
Hatier, C.2
Bissel, M.J.3
-
59
-
-
0034603197
-
New roles in Src kinases in control of cell survival and angiogenesis
-
Schlessinger J. New roles in Src kinases in control of cell survival and angiogenesis. Cell 2000; 100: 293-6.
-
(2000)
Cell
, vol.100
, pp. 293-296
-
-
Schlessinger, J.1
-
60
-
-
0027466849
-
High affinity VEGF binding and developmental expression suggest Flk-I as a major regulator of vasculogenesis and angiogenesis
-
Millauer B, Wizigmann-Voos S, Schnurch H, Martinez R, Moller NP, Risau W, et al. High affinity VEGF binding and developmental expression suggest Flk-I as a major regulator of vasculogenesis and angiogenesis. Cell 1993; 72: 835-46.
-
(1993)
Cell
, vol.72
, pp. 835-846
-
-
Millauer, B.1
Wizigmann-Voos, S.2
Schnurch, H.3
Martinez, R.4
Moller, N.P.5
Risau, W.6
-
61
-
-
85044705433
-
Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-I, following VEGF stimulation of vascular endothelial cells
-
Chou MT, Wang J, Fujita DJ. Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-I, following VEGF stimulation of vascular endothelial cells. BMC Biochem 2002; 3: 32.
-
(2002)
BMC Biochem
, vol.3
, pp. 32
-
-
Chou, M.T.1
Wang, J.2
Fujita, D.J.3
-
62
-
-
0030659531
-
V-SRC induces expression of hypoxia-inducible factor 1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1: Involvement of HIF-1 in tumor progression
-
Jiang BH, Agani F, Passaniti A, Semenza GL. V-SRC induces expression of hypoxia-inducible factor 1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1: involvement of HIF-1 in tumor progression. Cancer Res 1997; 57: 5328-35.
-
(1997)
Cancer Res
, vol.57
, pp. 5328-5335
-
-
Jiang, B.H.1
Agani, F.2
Passaniti, A.3
Semenza, G.L.4
-
63
-
-
1942502894
-
Transcription factor having impact on vascular endothelial growth factor (VEGF) gene expression in angiogenesis
-
Jośko J, Mazurek M. Transcription factor having impact on vascular endothelial growth factor (VEGF) gene expression in angiogenesis. Med Sci Monit 2004; 10: RA89-98.
-
(2004)
Med Sci Monit
, vol.10
-
-
Jośko, J.1
Mazurek, M.2
-
64
-
-
22744438100
-
Mitochondrial reactive oxygen species and c-Src play a critical role in hypoxic response in vascular smooth muscle cells
-
Sato H, Sato M, Kanai H, Uchiyama T, Iso T, Ohyama Y, et al. Mitochondrial reactive oxygen species and c-Src play a critical role in hypoxic response in vascular smooth muscle cells. Cardiovascular Res 2005; 67: 714-22.
-
(2005)
Cardiovascular Res
, vol.67
, pp. 714-722
-
-
Sato, H.1
Sato, M.2
Kanai, H.3
Uchiyama, T.4
Iso, T.5
Ohyama, Y.6
-
65
-
-
0029068339
-
Hypoxic induction of human vascular endothelial growth factor expression trough c-Src activation
-
Mukhopadhyay D, Tsiokas L, Zhou XM, Foster D, Brugge JY, Sukhatme VP. Hypoxic induction of human vascular endothelial growth factor expression trough c-Src activation. Nature 1995; 375: 577-81.
-
(1995)
Nature
, vol.375
, pp. 577-581
-
-
Mukhopadhyay, D.1
Tsiokas, L.2
Zhou, X.M.3
Foster, D.4
Brugge, J.Y.5
Sukhatme, V.P.6
-
66
-
-
0001191028
-
Regulation of vascular endothelial growth factor expression in human colon carcinoma cells by activity of Src kinase
-
Fleming RY, Ellis LM, Parikh NU, Liu W, Staley CA, Gallick GE. Regulation of vascular endothelial growth factor expression in human colon carcinoma cells by activity of Src kinase. Surgery 1997; 122: 501-7.
-
(1997)
Surgery
, vol.122
, pp. 501-507
-
-
Fleming, R.Y.1
Ellis, L.M.2
Parikh, N.U.3
Liu, W.4
Staley, C.A.5
Gallick, G.E.6
-
67
-
-
0031985127
-
Down-regulation of vascular endothelial growth factor in a human colon carcinoma cell line transfcted with an antisense vector specific for c-Src
-
Ellis LM, Staley CA, Liu W, Fleming RYD, Parikh NU, Bucana CD, et al. Down-regulation of vascular endothelial growth factor in a human colon carcinoma cell line transfcted with an antisense vector specific for c-Src. J Biol Chem 1998; 273: 1052-7.
-
(1998)
J Biol Chem
, vol.273
, pp. 1052-1057
-
-
Ellis, L.M.1
Staley, C.A.2
Liu, W.3
Fleming, R.Y.D.4
Parikh, N.U.5
Bucana, C.D.6
-
68
-
-
0035884402
-
Central role of p53 on regulation of vascular permeability factor/vascular endothelial growth factor (VPF/ VEGF) expression in mammary carcinoma
-
Pal S, Datta K, Mukhopadhyay D. Central role of p53 on regulation of vascular permeability factor/vascular endothelial growth factor (VPF/ VEGF) expression in mammary carcinoma. Cancer Res 2001; 61: 6952-7.
-
(2001)
Cancer Res
, vol.61
, pp. 6952-6957
-
-
Pal, S.1
Datta, K.2
Mukhopadhyay, D.3
-
69
-
-
0033393771
-
Selective requirements for Src kinases during VEGF-induced angiogenesis and vascular permeability
-
Eliceiri BP, Paul R, Schwartzberg PL, Hod JD, Leng J, Cheresh DA. Selective requirements for Src kinases during VEGF-induced angiogenesis and vascular permeability. Mol Cell 1999; 4: 915-24.
-
(1999)
Mol Cell
, vol.4
, pp. 915-924
-
-
Eliceiri, B.P.1
Paul, R.2
Schwartzberg, P.L.3
Hod, J.D.4
Leng, J.5
Cheresh, D.A.6
-
70
-
-
0035129504
-
Src deficiency or blockade of Src activity in mice provides cerebral protection following stroke
-
Paul R, Zhang ZG, Eliceiri BP, Jiang Q, Boccia AD, Zhang RL, et al. Src deficiency or blockade of Src activity in mice provides cerebral protection following stroke. Nat Med 2001; 7: 222-7.
-
(2001)
Nat Med
, vol.7
, pp. 222-227
-
-
Paul, R.1
Zhang, Z.G.2
Eliceiri, B.P.3
Jiang, Q.4
Boccia, A.D.5
Zhang, R.L.6
-
71
-
-
0033797255
-
VEGF enhances angiogenesis and promotes blood-barrier leakage in the ischemic brain
-
Zhang ZG, Zhang L, Jiang Q, Zhang R, Davies K, Powers C, et al. VEGF enhances angiogenesis and promotes blood-barrier leakage in the ischemic brain. J Clin Invest 2000; 106: 829-38.
-
(2000)
J Clin Invest
, vol.106
, pp. 829-838
-
-
Zhang, Z.G.1
Zhang, L.2
Jiang, Q.3
Zhang, R.4
Davies, K.5
Powers, C.6
-
72
-
-
0035890906
-
Src mediates stimulation by vascular endothelial growth factor of the phosphorylation of focal adhesion kinase at tyrosine 861, and anti-apoptosis in endothelial cells
-
Abu-Ghazaleh R, Kabir J, Jia H, Lobo M, Zachary I. Src mediates stimulation by vascular endothelial growth factor of the phosphorylation of focal adhesion kinase at tyrosine 861, and anti-apoptosis in endothelial cells. Biochem J 2001; 360: 255-64.
-
(2001)
Biochem J
, vol.360
, pp. 255-264
-
-
Abu-Ghazaleh, R.1
Kabir, J.2
Jia, H.3
Lobo, M.4
Zachary, I.5
-
73
-
-
3042842588
-
Activation of diacylglycerol kinase α is required for VEGF-induced angiogenic signaling in vitro
-
Baldanzi G, Mitola S, Cutrupi S, Filigheddu N, van Blitterswijk W, Sinigaglia F, et al. Activation of diacylglycerol kinase α is required for VEGF-induced angiogenic signaling in vitro. Oncogene 2004; 23: 4828-38.
-
(2004)
Oncogene
, vol.23
, pp. 4828-4838
-
-
Baldanzi, G.1
Mitola, S.2
Cutrupi, S.3
Filigheddu, N.4
van Blitterswijk, W.5
Sinigaglia, F.6
-
74
-
-
85047695527
-
Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis
-
Ni G, Wright KL, Huang M, Song L, Haura E, Turkson J, et al. Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis. Oncogene 2002; 21: 2000-8.
-
(2002)
Oncogene
, vol.21
, pp. 2000-2008
-
-
Ni, G.1
Wright, K.L.2
Huang, M.3
Song, L.4
Haura, E.5
Turkson, J.6
-
75
-
-
1042302005
-
The STATs of cancer-New molecular target come of age
-
Yu H, Jove R. The STATs of cancer-New molecular target come of age. Nature Rev Cancer 2004; 4: 97-105.
-
(2004)
Nature Rev Cancer
, vol.4
, pp. 97-105
-
-
Yu, H.1
Jove, R.2
-
76
-
-
24644457736
-
Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signalling pathways
-
Xu Q, Briggs J, Park S, Niu G, Kortylewski M, Zhang S, et al. Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signalling pathways. Oncogene 2005; 24: 5552-60.
-
(2005)
Oncogene
, vol.24
, pp. 5552-5560
-
-
Xu, Q.1
Briggs, J.2
Park, S.3
Niu, G.4
Kortylewski, M.5
Zhang, S.6
-
77
-
-
11144353715
-
Up-regulation of vascular endothelial growth factor-A by active membrane-type 1 matrix metalloproteinase through activation of Src-tyrosine kinases
-
Sounni NE, Roghi C, Chabottaux V, Janssen M, Munaut C, Maquoi E, et al. Up-regulation of vascular endothelial growth factor-A by active membrane-type 1 matrix metalloproteinase through activation of Src-tyrosine kinases. J Biol Chem 2004; 279: 13564-74.
-
(2004)
J Biol Chem
, vol.279
, pp. 13564-13574
-
-
Sounni, N.E.1
Roghi, C.2
Chabottaux, V.3
Janssen, M.4
Munaut, C.5
Maquoi, E.6
-
78
-
-
0142058167
-
Pyrrolopyrimidine c-Src inhibitors reduce growth, adhesion, motility and invasion of prostate cancer cells in vitro
-
Recchia I, Rucci N, Festuccia C, Bologna M, MacKay AR, Migliaccio S, et al. Pyrrolopyrimidine c-Src inhibitors reduce growth, adhesion, motility and invasion of prostate cancer cells in vitro. Eur J Cancer 2003; 39: 1927-35.
-
(2003)
Eur J Cancer
, vol.39
, pp. 1927-1935
-
-
Recchia, I.1
Rucci, N.2
Festuccia, C.3
Bologna, M.4
MacKay, A.R.5
Migliaccio, S.6
-
79
-
-
1442278553
-
Vascular endothelial growth factor-mediated activation of p38 is dependent upon Src and RAFTK/Pyk2
-
McMullen M, Keller R, Sussman M, Pumiglia K. Vascular endothelial growth factor-mediated activation of p38 is dependent upon Src and RAFTK/Pyk2. Oncogene 2004; 23: 1275-82.
-
(2004)
Oncogene
, vol.23
, pp. 1275-1282
-
-
McMullen, M.1
Keller, R.2
Sussman, M.3
Pumiglia, K.4
-
80
-
-
25844467656
-
c-Src regulates constitutive and EGF-mediated VEGF expression in pancreatic tumor cells through activation of phosphatidyl inositol-3 kinase and p38 MAPK
-
Summy JM, Trevino JG, Baker CH, Gallick GE. c-Src regulates constitutive and EGF-mediated VEGF expression in pancreatic tumor cells through activation of phosphatidyl inositol-3 kinase and p38 MAPK. Pancreas 2005; 31: 263-74.
-
(2005)
Pancreas
, vol.31
, pp. 263-274
-
-
Summy, J.M.1
Trevino, J.G.2
Baker, C.H.3
Gallick, G.E.4
-
81
-
-
0031459892
-
Angiogenesis promoted by vascular endothelial growth factor: Regulation through α1β1 and α2β1 integrins
-
Senger DR, Claffey KP, Benes JE, Perruzzi CA, Sergiou AP, Detmar M. Angiogenesis promoted by vascular endothelial growth factor: regulation through α1β1 and α2β1 integrins. Proc Nat Acad Sci USA 1997; 94: 13612-7.
-
(1997)
Proc Nat Acad Sci USA
, vol.94
, pp. 13612-13617
-
-
Senger, D.R.1
Claffey, K.P.2
Benes, J.E.3
Perruzzi, C.A.4
Sergiou, A.P.5
Detmar, M.6
-
82
-
-
1542283690
-
Matrix-specific activation of Src and Rho initiates capillary morphogenesis of endothelial cells
-
Liu Y, Senger DR. Matrix-specific activation of Src and Rho initiates capillary morphogenesis of endothelial cells. FASEB 2004; 18: 457-68.
-
(2004)
FASEB
, vol.18
, pp. 457-468
-
-
Liu, Y.1
Senger, D.R.2
-
83
-
-
0034607633
-
Norepinefrine induces vascular endothelial growth factor gene expression in brown adipocytes through a β-adrenoreceptor/cAMP/protein kinase, a pathway involving Src but independently of Erk1/2
-
Fredriksson JM, Lindquist JM, Bronnikov GE, Nedergaard J. Norepinefrine induces vascular endothelial growth factor gene expression in brown adipocytes through a β-adrenoreceptor/cAMP/protein kinase, a pathway involving Src but independently of Erk1/2. J Biol Chem 2000; 75: 13802-11.
-
(2000)
J Biol Chem
, vol.75
, pp. 13802-13811
-
-
Fredriksson, J.M.1
Lindquist, J.M.2
Bronnikov, G.E.3
Nedergaard, J.4
-
84
-
-
0242333907
-
Inactivation of Src family kinases inhibits angiogenesis in vivo: Implication for a mechanism involving organization of the actin cytoskeleton
-
Kilarski WW, Jura N, Gerwins P. Inactivation of Src family kinases inhibits angiogenesis in vivo: implication for a mechanism involving organization of the actin cytoskeleton. Exp Cell Res 2003; 291: 70-82.
-
(2003)
Exp Cell Res
, vol.291
, pp. 70-82
-
-
Kilarski, W.W.1
Jura, N.2
Gerwins, P.3
-
85
-
-
0028157827
-
Modulation of platelet-derived growth factor receptor expression in microvascular endothelial cells during in vitro angiogenesis
-
Marx M, Perlmutter MA, Madri JA. Modulation of platelet-derived growth factor receptor expression in microvascular endothelial cells during in vitro angiogenesis. J Clin Invest 1994; 93: 131-9.
-
(1994)
J Clin Invest
, vol.93
, pp. 131-139
-
-
Marx, M.1
Perlmutter, M.A.2
Madri, J.A.3
-
86
-
-
0034968914
-
c-src modulates microvascular endothelial phenotype and in vitro angiogenesis
-
c-src modulates microvascular endothelial phenotype and in vitro angiogenesis. Exp Mol Pathol 2001; 70: 201-13.
-
(2001)
Exp Mol Pathol
, vol.70
, pp. 201-213
-
-
Marx, M.1
Warren, S.L.2
Madri, J.A.3
-
87
-
-
0036510762
-
TNF-related activation-induced cytokine (TRANCE) induces angiogenesis through the activation of Src and phospholipase C (PLC) in human endothelial cells
-
Kim YM, Kim YM, Lee YM, Kim HS, Kim JD, Choi Y, et al. TNF-related activation-induced cytokine (TRANCE) induces angiogenesis through the activation of Src and phospholipase C (PLC) in human endothelial cells. J Biol Chem 2002; 277: 6799-805.
-
(2002)
J Biol Chem
, vol.277
, pp. 6799-6805
-
-
Kim, Y.M.1
Kim, Y.M.2
Lee, Y.M.3
Kim, H.S.4
Kim, J.D.5
Choi, Y.6
-
88
-
-
0034666326
-
Factor VIIa/Tissue Factor-induced signalling via activation of Src-like kinases, phosphatidylinositol 3-kinase, and Rac
-
Versteeg HH, Hoedemaeker I, Diks SH, Stam JC, Spaargaren M, van Bergen en Henegouwen PM, et al. Factor VIIa/Tissue Factor-induced signalling via activation of Src-like kinases, phosphatidylinositol 3-kinase, and Rac. J Biol Chem 2000; 275: 28750-6.
-
(2000)
J Biol Chem
, vol.275
, pp. 28750-28756
-
-
Versteeg, H.H.1
Hoedemaeker, I.2
Diks, S.H.3
Stam, J.C.4
Spaargaren, M.5
van Bergen en Henegouwen, P.M.6
-
89
-
-
0029127230
-
Angiogenesis mediated by soluble forms of E-selectin and vascular cell adhesion molecule-1
-
Kock AE, Halloran MM, Haskell CJ, Shah MR, Polverini PJ. Angiogenesis mediated by soluble forms of E-selectin and vascular cell adhesion molecule-1. Nature 1995; 376: 517-9.
-
(1995)
Nature
, vol.376
, pp. 517-519
-
-
Kock, A.E.1
Halloran, M.M.2
Haskell, C.J.3
Shah, M.R.4
Polverini, P.J.5
-
90
-
-
0037589020
-
Src and phosphatidylinositol 3-kinase mediate soluble E-selectin-induced angiogenesis
-
Kumar P, Amin MA, Harlow LA, Polverini PJ, Koch AE. Src and phosphatidylinositol 3-kinase mediate soluble E-selectin-induced angiogenesis. Blood 2003; 101: 3960-8.
-
(2003)
Blood
, vol.101
, pp. 3960-3968
-
-
Kumar, P.1
Amin, M.A.2
Harlow, L.A.3
Polverini, P.J.4
Koch, A.E.5
-
91
-
-
20444467285
-
Characterization of heparin affin regulatory peptide signalling in human endothelial cells
-
Polykratis A, Katsoris P, Courty J, Papadimitriou E. Characterization of heparin affin regulatory peptide signalling in human endothelial cells. J Biol Chem 2005; 280: 22454-61.
-
(2005)
J Biol Chem
, vol.280
, pp. 22454-22461
-
-
Polykratis, A.1
Katsoris, P.2
Courty, J.3
Papadimitriou, E.4
-
92
-
-
23844530826
-
Expression and activity of Src regulate interleukin-8 expression in pancreatic adenocarcinoma cells: Implication for angiogenesis
-
Trevino JG, Summy JM, Gray MJ, Nilsson MB, Lesslie DP, Baker CH, et al. Expression and activity of Src regulate interleukin-8 expression in pancreatic adenocarcinoma cells: implication for angiogenesis. Cancer Res 2005; 65: 7214-22.
-
(2005)
Cancer Res
, vol.65
, pp. 7214-7222
-
-
Trevino, J.G.1
Summy, J.M.2
Gray, M.J.3
Nilsson, M.B.4
Lesslie, D.P.5
Baker, C.H.6
-
93
-
-
1842434391
-
Interleukin-8 confers androgen-independent growth and migration of LNCaP: Differential effects of tyrosine kinases Src and FAK
-
Lee L, Louie MC, Desai SJ, Yang J, Chen HW, Evans CP, et al. Interleukin-8 confers androgen-independent growth and migration of LNCaP: differential effects of tyrosine kinases Src and FAK. Oncogene 2004; 23: 2197-205.
-
(2004)
Oncogene
, vol.23
, pp. 2197-2205
-
-
Lee, L.1
Louie, M.C.2
Desai, S.J.3
Yang, J.4
Chen, H.W.5
Evans, C.P.6
-
94
-
-
1842431419
-
High-throughput structural biology in drug discovery: Protein kinases
-
Stout TJ, Foster PG, Matthews DJ. High-throughput structural biology in drug discovery: protein kinases. Curr Pharm Des 2004; 10: 1069-82.
-
(2004)
Curr Pharm Des
, vol.10
, pp. 1069-1082
-
-
Stout, T.J.1
Foster, P.G.2
Matthews, D.J.3
-
95
-
-
25444479747
-
Recent advances in the discovery of Src kinases inhibitors
-
Parang K, Sun G. Recent advances in the discovery of Src kinases inhibitors. Expert Opin Ther Patents 2005; 15: 1183-207.
-
(2005)
Expert Opin Ther Patents
, vol.15
, pp. 1183-1207
-
-
Parang, K.1
Sun, G.2
-
96
-
-
0346214475
-
Discovery of a novel family of CDK inhibitors with the program LIDAEUS: Structural basis for ligand-induced disordering of the activation loop
-
Wu SY, McNae I, Kontopidis G, McClue SJ, McInnes C, Stewart KJ, et al. Discovery of a novel family of CDK inhibitors with the program LIDAEUS: structural basis for ligand-induced disordering of the activation loop. Structure 2003; 11: 399-410.
-
(2003)
Structure
, vol.11
, pp. 399-410
-
-
Wu, S.Y.1
McNae, I.2
Kontopidis, G.3
McClue, S.J.4
McInnes, C.5
Stewart, K.J.6
-
97
-
-
0033794834
-
Small molecule inhibitors of Src family kinases
-
Boschelli DH, Boschelli F. Small molecule inhibitors of Src family kinases. Drug Future 2000; 25: 717-36.
-
(2000)
Drug Future
, vol.25
, pp. 717-736
-
-
Boschelli, D.H.1
Boschelli, F.2
-
98
-
-
0030029143
-
Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation
-
Hanke JH, Gardner JP, Dow RL, Changelian PS, Brissette WH, Weringer EJ, et al. Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation. J Biol Chem 1996; 271: 695-701.
-
(1996)
J Biol Chem
, vol.271
, pp. 695-701
-
-
Hanke, J.H.1
Gardner, J.P.2
Dow, R.L.3
Changelian, P.S.4
Brissette, W.H.5
Weringer, E.J.6
-
99
-
-
1842414894
-
Src family-selective tyrosine kinase inhibitor, PP1, inhibits both Fc epsilonRI- and Thy-1-mediated activation of rat basophilic leukemia cells
-
Amoui M, Draber P, Draberova L. Src family-selective tyrosine kinase inhibitor, PP1, inhibits both Fc epsilonRI- and Thy-1-mediated activation of rat basophilic leukemia cells. Eur J Immunol 1997; 27: 1881-6.
-
(1997)
Eur J Immunol
, vol.27
, pp. 1881-1886
-
-
Amoui, M.1
Draber, P.2
Draberova, L.3
-
100
-
-
0033200390
-
Structural basis for selective inhibition of Src family kinases by PP1
-
Liu Y, Bishop A, Witucki L, Kraybill B, Shimizu E, Tsien J, et al. Structural basis for selective inhibition of Src family kinases by PP1. Chem Biol 1999; 6: 671-8.
-
(1999)
Chem Biol
, vol.6
, pp. 671-678
-
-
Liu, Y.1
Bishop, A.2
Witucki, L.3
Kraybill, B.4
Shimizu, E.5
Tsien, J.6
-
101
-
-
0037468159
-
The pp60c-Src inhibitor PP1 is non-competitive against ATP
-
Karni R, Mizrachi S, Reiss-Sklan E, Gazit A, Livnah O, Levitzki A. The pp60c-Src inhibitor PP1 is non-competitive against ATP. FEBS Lett 2003; 537: 47-52.
-
(2003)
FEBS Lett
, vol.537
, pp. 47-52
-
-
Karni, R.1
Mizrachi, S.2
Reiss-Sklan, E.3
Gazit, A.4
Livnah, O.5
Levitzki, A.6
-
102
-
-
6344226300
-
Antiproliferative activity of 1-aryl-4-amino substituted 1H-pyrazolo[3,4-d]pyrimidine derivatives toward the human epidermoid carcinoma A431 cell line
-
Schenone S, Bruno O, Bondavalli F, Ranise A, Mosti L, Menozzi G, et al. Antiproliferative activity of 1-aryl-4-amino substituted 1H-pyrazolo[3,4-d]pyrimidine derivatives toward the human epidermoid carcinoma A431 cell line. Eur J Med Chem 2004; 39: 939-46.
-
(2004)
Eur J Med Chem
, vol.39
, pp. 939-946
-
-
Schenone, S.1
Bruno, O.2
Bondavalli, F.3
Ranise, A.4
Mosti, L.5
Menozzi, G.6
-
103
-
-
33846827051
-
Pyrazolo-pyrimidine-derived c-Src inhibitor reduces angiogenesis and survival of squamous carcinoma cells by suppressing vascular endothelial growth factor production and signaling
-
Donnini S, Monti M, Castagnini C, Solito R, Botta M, Schenone S, et al. Pyrazolo-pyrimidine-derived c-Src inhibitor reduces angiogenesis and survival of squamous carcinoma cells by suppressing vascular endothelial growth factor production and signaling. Int J Cancer 2007; 120: 995-1004.
-
(2007)
Int J Cancer
, vol.120
, pp. 995-1004
-
-
Donnini, S.1
Monti, M.2
Castagnini, C.3
Solito, R.4
Botta, M.5
Schenone, S.6
-
104
-
-
0032904762
-
A novel inhibitor of the tyrosine kinase Src suppresses phosphorylation of its major cellular substrates and reduces bone resorption in vitro and in rodent models in vivo
-
Missbach M, Jeschke M, Feyen J, Müller K, Glatt M, Green J, et al. A novel inhibitor of the tyrosine kinase Src suppresses phosphorylation of its major cellular substrates and reduces bone resorption in vitro and in rodent models in vivo. Bone 1999; 24: 437-49.
-
(1999)
Bone
, vol.24
, pp. 437-449
-
-
Missbach, M.1
Jeschke, M.2
Feyen, J.3
Müller, K.4
Glatt, M.5
Green, J.6
-
105
-
-
0942289886
-
Reduction of c-Src activity by substituted 5,7-diphenyl-pyrrolo [2,3-d]-pyrimidines induces osteoclast apoptosis in vivo and in vitro. Involvement of ERK1/2 pathway
-
Recchia I, Rucci N, Funari A, Migliaccio S, Taranta A, Longo M, et al. Reduction of c-Src activity by substituted 5,7-diphenyl-pyrrolo [2,3-d]-pyrimidines induces osteoclast apoptosis in vivo and in vitro. Involvement of ERK1/2 pathway. Bone 2004; 34: 65-79.
-
(2004)
Bone
, vol.34
, pp. 65-79
-
-
Recchia, I.1
Rucci, N.2
Funari, A.3
Migliaccio, S.4
Taranta, A.5
Longo, M.6
-
106
-
-
33745257077
-
Inhibition of protein kinase c-src reduces the incidence of breast cancer metastases and increases survival in mice. implications for therapy
-
Rucci N, Recchia I, Angelucci A, Alamanou M, Del Fattore A, Fortunati D, et al. Inhibition of protein kinase c-src reduces the incidence of breast cancer metastases and increases survival in mice. implications for therapy. J Pharmacol Exp Ther 2006; 318: 161-72.
-
(2006)
J Pharmacol Exp Ther
, vol.318
, pp. 161-172
-
-
Rucci, N.1
Recchia, I.2
Angelucci, A.3
Alamanou, M.4
Del Fattore, A.5
Fortunati, D.6
-
107
-
-
1842836011
-
Src family kinase activity is required for signal tranducer and activator of transcription 3 and focal adhesion kinase phosphorylation and vascular endothelial growth factor signaling in vivo and for anchorage-dependent and -independent growth of human tumor cells
-
Laird AD, Li G, Moss KG, Blake RA, Broome MA, Cherrington JM, et al. Src family kinase activity is required for signal tranducer and activator of transcription 3 and focal adhesion kinase phosphorylation and vascular endothelial growth factor signaling in vivo and for anchorage-dependent and -independent growth of human tumor cells. Mol Cancer Ther 2003; 2: 461-9.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 461-469
-
-
Laird, A.D.1
Li, G.2
Moss, K.G.3
Blake, R.A.4
Broome, M.A.5
Cherrington, J.M.6
-
108
-
-
0034424220
-
Src inhibitors: Drugs for the treatment of osteoporosis, cancer or both?
-
Susva M, Missbach M, Green J. Src inhibitors: drugs for the treatment of osteoporosis, cancer or both? Trends Pharmacol Sci 2000; 21: 489-95.
-
(2000)
Trends Pharmacol Sci
, vol.21
, pp. 489-495
-
-
Susva, M.1
Missbach, M.2
Green, J.3
-
109
-
-
25144523329
-
Crystal structures of active SRC kinase domain complexes
-
Breitenlechner CB, Kairies NA, Honold K, Scheiblich S, Koll H, Greiter E, et al. Crystal structures of active SRC kinase domain complexes. J Mol Biol 2005; 353: 222-31.
-
(2005)
J Mol Biol
, vol.353
, pp. 222-231
-
-
Breitenlechner, C.B.1
Kairies, N.A.2
Honold, K.3
Scheiblich, S.4
Koll, H.5
Greiter, E.6
-
110
-
-
30344460024
-
AP23846, a novel and highly potent Src family kinase inhibitor, reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines and abrogates downstream angiogenic processes
-
Summy JM, Trevino JG, Lesslie DP, Baker CH, Shakespeare WC, Wang Y, et al. AP23846, a novel and highly potent Src family kinase inhibitor, reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines and abrogates downstream angiogenic processes. Mol Canc Ther 2005; 4: 1900-11.
-
(2005)
Mol Canc Ther
, vol.4
, pp. 1900-1911
-
-
Summy, J.M.1
Trevino, J.G.2
Lesslie, D.P.3
Baker, C.H.4
Shakespeare, W.C.5
Wang, Y.6
-
111
-
-
0034458943
-
SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling
-
Blake RA, Broome MA, Liu X, Wu J, Gishizky M, Sun L, et al. SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling. Mol Cell Biol 2000; 20: 9018-27.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 9018-9027
-
-
Blake, R.A.1
Broome, M.A.2
Liu, X.3
Wu, J.4
Gishizky, M.5
Sun, L.6
-
112
-
-
15444353988
-
-
Klutchko SR, Hamby JM, Boschelli DH, Wu Z, Kraker AJ, Amar AM, et al. 2-Substituted aminopyrido[2,3-d]pyrimidin-7(8H)-ones. Structure-activity relationships against selected tyrosine kinases and in vitro and in vivo anticancer activity. J Med Chem 1998; 41: 3276-92.
-
Klutchko SR, Hamby JM, Boschelli DH, Wu Z, Kraker AJ, Amar AM, et al. 2-Substituted aminopyrido[2,3-d]pyrimidin-7(8H)-ones. Structure-activity relationships against selected tyrosine kinases and in vitro and in vivo anticancer activity. J Med Chem 1998; 41: 3276-92.
-
-
-
-
113
-
-
0031471249
-
In vitro pharmacological characterization of PD166285, a new nanomolar potent and broadly active protein tyrosine kinase inhibitor
-
Panek RL, Lu GH, Klutchko SR, Batley BL, Dahring TK, Hamby JM, et al. In vitro pharmacological characterization of PD166285, a new nanomolar potent and broadly active protein tyrosine kinase inhibitor. J Pharmacol Exp Ther 1997; 283: 1433-44.
-
(1997)
J Pharmacol Exp Ther
, vol.283
, pp. 1433-1444
-
-
Panek, R.L.1
Lu, G.H.2
Klutchko, S.R.3
Batley, B.L.4
Dahring, T.K.5
Hamby, J.M.6
-
114
-
-
0032761526
-
Anti-angiogenic activity of selected receptor tyrosine kinase inhibitors, PD166285 and PD173074: Implications for combination treatment with photodynamic therapy
-
Dimitroff CJ, Klohs W, Sharma A, Pera P, Driscoll D, Veith J, et al. Anti-angiogenic activity of selected receptor tyrosine kinase inhibitors, PD166285 and PD173074: implications for combination treatment with photodynamic therapy. Invest New Drugs 1999; 17: 121-35.
-
(1999)
Invest New Drugs
, vol.17
, pp. 121-135
-
-
Dimitroff, C.J.1
Klohs, W.2
Sharma, A.3
Pera, P.4
Driscoll, D.5
Veith, J.6
-
115
-
-
0032554818
-
Development of a binding model to protein tyrosine kinases for substituted pyrido[2,3-d]pyrimidine inhibitors
-
Trumpp-Kallmeyer S, Rubin JR, Humblet C, Hamby JM, Showalter HD. Development of a binding model to protein tyrosine kinases for substituted pyrido[2,3-d]pyrimidine inhibitors. J Med Chem 1998; 41: 1752-63.
-
(1998)
J Med Chem
, vol.41
, pp. 1752-1763
-
-
Trumpp-Kallmeyer, S.1
Rubin, J.R.2
Humblet, C.3
Hamby, J.M.4
Showalter, H.D.5
-
116
-
-
15044361867
-
Structure-activity relationships for 2-anilino-6-phenylpyrido[2,3-d]pyrimidin-7(8H)-ones as inhibitors of the cellular checkpoint kinase Wee1
-
Palmer BD, Smaill JB, Rewcastle GW, Dobrusin EM, Kraker A, Moore CW, et al. Structure-activity relationships for 2-anilino-6-phenylpyrido[2,3-d]pyrimidin-7(8H)-ones as inhibitors of the cellular checkpoint kinase Wee1. Bioorg Med Chem Lett 2005; 15: 1931-5.
-
(2005)
Bioorg Med Chem Lett
, vol.15
, pp. 1931-1935
-
-
Palmer, B.D.1
Smaill, J.B.2
Rewcastle, G.W.3
Dobrusin, E.M.4
Kraker, A.5
Moore, C.W.6
-
117
-
-
0842304432
-
Discovery of a new class of anilinoquinazoline inhibitors with high affinity and specificity for the tyrosine kinase domain of c-Src
-
Plé PA, Green TP, Hennequin LF, Curwen J, Fennel M, Allen J, et al. Discovery of a new class of anilinoquinazoline inhibitors with high affinity and specificity for the tyrosine kinase domain of c-Src. J Med Chem 2004; 47: 871-87.
-
(2004)
J Med Chem
, vol.47
, pp. 871-887
-
-
Plé, P.A.1
Green, T.P.2
Hennequin, L.F.3
Curwen, J.4
Fennel, M.5
Allen, J.6
-
118
-
-
9744242077
-
Inhibition of SRC tyrosine kinase as treatment for human pancreatic cancer growing orthotopically in nude mice
-
Yezhelyev MV, Koehl G, Guba M, Brabletz T, Jauch KW, Ryan A, et al. Inhibition of SRC tyrosine kinase as treatment for human pancreatic cancer growing orthotopically in nude mice. Clin Cancer Res 2004; 10: 8028-36.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8028-8036
-
-
Yezhelyev, M.V.1
Koehl, G.2
Guba, M.3
Brabletz, T.4
Jauch, K.W.5
Ryan, A.6
-
119
-
-
24744432879
-
Src tyrosine kinase inhibitor, M475271, suppresses subcutaneous growth and production of lung metastasis via inhibition of proliferation, invasion, and vascularization of human lung adenocarcinoma cells
-
Zheng R, Yano S, Matsumori Y, Nakataki E, Muguruma H, Yoshizumi M, et al. Src tyrosine kinase inhibitor, M475271, suppresses subcutaneous growth and production of lung metastasis via inhibition of proliferation, invasion, and vascularization of human lung adenocarcinoma cells. Clin Exp Metastasis 2005; 22:195-204.
-
(2005)
Clin Exp Metastasis
, vol.22
, pp. 195-204
-
-
Zheng, R.1
Yano, S.2
Matsumori, Y.3
Nakataki, E.4
Muguruma, H.5
Yoshizumi, M.6
-
120
-
-
21744435561
-
A novel Src kinase inhibitor, M475271, inhibits VEGF-induced human umbilical vein endothelial cell proliferation and migration
-
Ali N, Yoshizumi M, FujitaY, Izawa Y, Kanematsu Y, Ishizawa K, et al. A novel Src kinase inhibitor, M475271, inhibits VEGF-induced human umbilical vein endothelial cell proliferation and migration. J Pharmacol Sci 2005; 98: 130-41.
-
(2005)
J Pharmacol Sci
, vol.98
, pp. 130-141
-
-
Ali, N.1
Yoshizumi, M.2
Fujita, Y.3
Izawa, Y.4
Kanematsu, Y.5
Ishizawa, K.6
-
121
-
-
0035430177
-
Suppression of angiogenesis, tumor growth, and wound healing by resveratrol, a natural compound in red wine and grapes
-
Brakenhielm E, Cao R, Cao Y. Suppression of angiogenesis, tumor growth, and wound healing by resveratrol, a natural compound in red wine and grapes. FASEB J 2002; 15: 1798-800.
-
(2002)
FASEB J
, vol.15
, pp. 1798-1800
-
-
Brakenhielm, E.1
Cao, R.2
Cao, Y.3
-
122
-
-
0142210188
-
Inhibition of vascular endothelial growth factor-induced angiogenesis by resveratrol through interruption of Src-dependent vascular endothelial cadherin phosphorylation
-
Lin MT, Yen ML, Lin CY, Kuo ML. Inhibition of vascular endothelial growth factor-induced angiogenesis by resveratrol through interruption of Src-dependent vascular endothelial cadherin phosphorylation. Mol Pharmacol 2003; 64: 1029-36.
-
(2003)
Mol Pharmacol
, vol.64
, pp. 1029-1036
-
-
Lin, M.T.1
Yen, M.L.2
Lin, C.Y.3
Kuo, M.L.4
-
123
-
-
33745120853
-
Anti-angiogenic peptides and proteins: From experimental tools to clinical drugs
-
Rüegg C, Hasmim M, Lejeune FJ, Alghisi GC. Anti-angiogenic peptides and proteins: From experimental tools to clinical drugs. Bioch Biophys Acta 2006; 1765: 155-77.
-
(2006)
Bioch Biophys Acta
, vol.1765
, pp. 155-177
-
-
Rüegg, C.1
Hasmim, M.2
Lejeune, F.J.3
Alghisi, G.C.4
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