Insulin potentiates Ca2+ signaling and phosphatidylinositol 4,5-bisphosphate hydrolysis induced by Gq protein-coupled receptor agonists through an mTOR-dependent pathway

Endocrinology

Volumn 148, Issue 7, 2007, Pages 3246-3257

  Kisfalvi, Krisztina ^a   Rey, Osvaldo ^a   Young, Steven H ^a   Sinnett Smith, James ^a   Rozengurt, Enrique ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II; BOMBESIN; BRADYKININ; CALCIUM; G PROTEIN COUPLED RECEPTOR; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; NEUROTENSIN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; VASOPRESSIN; INOSITOL 1,4,5 TRISPHOSPHATE; MARCKS PROTEIN; MEMBRANE PROTEIN; MYRISTOYLATED ALANINE-RICH C KINASE SUBSTRATE; PROTEIN KINASE; RAPAMYCIN; SIGNAL PEPTIDE; UNCLASSIFIED DRUG; VASOPRESSIN DERIVATIVE;

ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; DOSE RESPONSE; HUMAN; HUMAN CELL; HYDROLYSIS; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR CELL; CALCIUM SIGNALING; DRUG EFFECT; DRUG POTENTIATION; FLUORESCENCE MICROSCOPY; METABOLISM; PANCREAS TUMOR; PATHOLOGY; PHOSPHORYLATION; TUMOR CELL LINE; WESTERN BLOTTING;

ANGIOTENSIN II; BLOTTING, WESTERN; BOMBESIN; BRADYKININ; CALCIUM SIGNALING; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYDROLYSIS; INOSITOL 1,4,5-TRISPHOSPHATE; INSULIN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICROSCOPY, FLUORESCENCE; NEUROTENSIN; PANCREATIC NEOPLASMS; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHORYLATION; PROTEIN KINASES; RECEPTORS, G-PROTEIN-COUPLED; SIROLIMUS; VASOPRESSINS;

EID: 34347261370     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2006-1711     Document Type: Article

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