-
1
-
-
0033989031
-
Cardiac protection: Evolving role of angiotensin receptor blockers
-
Califf RM, Cohn JN. Cardiac protection: evolving role of angiotensin receptor blockers. Am Heart J 2000; 139 (Suppl. 1):S15-S22.
-
(2000)
Am Heart J
, vol.139
, Issue.1 SUPPL.
-
-
Califf, R.M.1
Cohn, J.N.2
-
2
-
-
0025077634
-
Determinants of angiotensin II generation during converting enzyme inhibition
-
Juillerat L, Nussberger J, Menard J, et al. Determinants of angiotensin II generation during converting enzyme inhibition. Hypertension 1990; 16:564-572.
-
(1990)
Hypertension
, vol.16
, pp. 564-572
-
-
Juillerat, L.1
Nussberger, J.2
Menard, J.3
-
3
-
-
0033507945
-
Neurohormonal reactivation in heart failure patients on chronic ACE inhibitor therapy: A longitudinal study
-
Lee AF, MacFadyen RJ, Struthers AD. Neurohormonal reactivation in heart failure patients on chronic ACE inhibitor therapy: a longitudinal study. Eur J Heart Fail 1999; 1:401-406.
-
(1999)
Eur J Heart Fail
, vol.1
, pp. 401-406
-
-
Lee, A.F.1
MacFadyen, R.J.2
Struthers, A.D.3
-
4
-
-
0035869572
-
Angiotensin converting enzyme (ACE) and non-ACE dependent angiotensin II generation in resistance arteries from patients with heart failure and coronary heart disease
-
Petrie MC, Padmanabhan N, McDonald JE, et al. Angiotensin converting enzyme (ACE) and non-ACE dependent angiotensin II generation in resistance arteries from patients with heart failure and coronary heart disease. J Am Coll Cardiol 2001; 37:1056-1061.
-
(2001)
J Am Coll Cardiol
, vol.37
, pp. 1056-1061
-
-
Petrie, M.C.1
Padmanabhan, N.2
McDonald, J.E.3
-
5
-
-
15844404186
-
Expression, localisation and function of ACE and chymase in normal and atherosclerotic human coronary arteries
-
Borland JA, Kelsall C, Yacoub MH, et al. Expression, localisation and function of ACE and chymase in normal and atherosclerotic human coronary arteries. Vascul Pharmacol 2005; 42:99-108.
-
(2005)
Vascul Pharmacol
, vol.42
, pp. 99-108
-
-
Borland, J.A.1
Kelsall, C.2
Yacoub, M.H.3
-
6
-
-
0023431536
-
Pig kidney angiotensin converting enzyme. Purification and characterization of amphipathic and hydrophilic forms of the enzyme establishes C-terminal anchorage to the plasma membrane
-
Hooper NM, Keen J, Pappin DJ, et al. Pig kidney angiotensin converting enzyme. Purification and characterization of amphipathic and hydrophilic forms of the enzyme establishes C-terminal anchorage to the plasma membrane. Biochem J 1987; 247:85-93.
-
(1987)
Biochem J
, vol.247
, pp. 85-93
-
-
Hooper, N.M.1
Keen, J.2
Pappin, D.J.3
-
7
-
-
0014957830
-
A dipeptidyl carboxypeptidase that converts angiotensin I and inactivates bradykinin
-
Yang HYT, Erdös EG, Levin Y. A dipeptidyl carboxypeptidase that converts angiotensin I and inactivates bradykinin. Biochim Biophys Acta 1970; 214:374-376.
-
(1970)
Biochim Biophys Acta
, vol.214
, pp. 374-376
-
-
Yang, H.Y.T.1
Erdös, E.G.2
Levin, Y.3
-
8
-
-
20044386111
-
Angiotensin-converting enzyme is a GPI-anchored protein releasing factor crucial for fertilization
-
Kondoh G, Tojo H, Nakatani Y, et al. Angiotensin-converting enzyme is a GPI-anchored protein releasing factor crucial for fertilization. Nat Med 2005; 11:160-166. This study reports that ACE possesses a glycosylphosphatidylinositol-anchored protein-releasing activity (glycosylphosphatidylinositol hydrolase activity). ACE shed various glycosylphosphatidylinositol-anchored proteins from the cell surface, including TESP5 and PH-20 from sperm membranes; a process that seems to be essential for fertility.
-
(2005)
Nat Med
, vol.11
, pp. 160-166
-
-
Kondoh, G.1
Tojo, H.2
Nakatani, Y.3
-
9
-
-
22744435012
-
Serine proteases and cardiac function
-
Wu Q, Kuo HC, Deng GG. Serine proteases and cardiac function. Biochim Biophys Acta 2005; 1751:82-94. A very informative current review that summarizes the multifunctional actions of different serine proteases.
-
(2005)
Biochim Biophys Acta
, vol.1751
, pp. 82-94
-
-
Wu, Q.1
Kuo, H.C.2
Deng, G.G.3
-
10
-
-
4544281877
-
Chymase as a novel target for the prevention of vascular diseases
-
Takai S, Jin D, Muramatsu M, et al. Chymase as a novel target for the prevention of vascular diseases. Trends Pharmacol Sci 2004; 25:518-522. A comment highlighting the importance of chymase and chymase inhibition in cases of abdominal aortic aneurysm and angiogenesis.
-
(2004)
Trends Pharmacol Sci
, vol.25
, pp. 518-522
-
-
Takai, S.1
Jin, D.2
Muramatsu, M.3
-
11
-
-
0038053724
-
A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9
-
Donoghue M, Hsieh F, Baronas E, et al. A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ Res 2000; 87:E1-E9.
-
(2000)
Circ Res
, vol.87
-
-
Donoghue, M.1
Hsieh, F.2
Baronas, E.3
-
12
-
-
0034721906
-
A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase
-
Tipnis SR, Hooper NM, Hyde R, et al. A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. J Biol Chem 2000; 275:33238-33243.
-
(2000)
J Biol Chem
, vol.275
, pp. 33238-33243
-
-
Tipnis, S.R.1
Hooper, N.M.2
Hyde, R.3
-
13
-
-
18544378161
-
Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase
-
Vickers C, Hales P, Kaushik V, et al. Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase. J Biol Chem 2002; 277:14838-14843.
-
(2002)
J Biol Chem
, vol.277
, pp. 14838-14843
-
-
Vickers, C.1
Hales, P.2
Kaushik, V.3
-
14
-
-
5044220674
-
Evidence against a major role for angiotensin converting enzyme-related carboxypeptidase (ACE2) in angiotensin peptide metabolism in the human coronary circulation
-
Campbell DJ, Zeitz CJ, Esler MD, et al. Evidence against a major role for angiotensin converting enzyme-related carboxypeptidase (ACE2) in angiotensin peptide metabolism in the human coronary circulation. J Hypertens 2004; 22:1971-1976.
-
(2004)
J Hypertens
, vol.22
, pp. 1971-1976
-
-
Campbell, D.J.1
Zeitz, C.J.2
Esler, M.D.3
-
16
-
-
26044453206
-
Protection from angiotensin II-induced cardiac hypertrophy and fibrosis by systemic lentiviral delivery of ACE2
-
Huentelman MJ, Grobe JL, Vazquez J, et al. Protection from angiotensin II-induced cardiac hypertrophy and fibrosis by systemic lentiviral delivery of ACE2. Exp Physiol 2005; 90:783-790. A study supporting the concept that ACE2 counteracts the effects of classic RAS activation. ACE2 overexpression protected against angiotensin II-induced cardiac hypertrophy and fibrosis in Sprague-Dawley rats.
-
(2005)
Exp Physiol
, vol.90
, pp. 783-790
-
-
Huentelman, M.J.1
Grobe, J.L.2
Vazquez, J.3
-
17
-
-
10744223104
-
Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins
-
Donoghue M, Wakimoto H, Maguire CT, et al. Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins. J Mol Cell Cardiol 2003; 35:1043-1053.
-
(2003)
J Mol Cell Cardiol
, vol.35
, pp. 1043-1053
-
-
Donoghue, M.1
Wakimoto, H.2
Maguire, C.T.3
-
18
-
-
0037142101
-
Angiotensin-converting enzyme 2 is an essential regulator of heart function
-
Crackower MA, Sarao R, Oudit GY, et al. Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature 2002; 417:822-828.
-
(2002)
Nature
, vol.417
, pp. 822-828
-
-
Crackower, M.A.1
Sarao, R.2
Oudit, G.Y.3
-
19
-
-
0344395657
-
Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus
-
Li W, Moore MJ, Vasilieva N, et al. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature 2003; 426:450-454.
-
(2003)
Nature
, vol.426
, pp. 450-454
-
-
Li, W.1
Moore, M.J.2
Vasilieva, N.3
-
20
-
-
23844463115
-
A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury
-
Kuba K, Imai Y, Rao S, et al. A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury. Nat Med 2005; 11:875-879. A study providing a molecular explanation as to why severe acute respiratory syndrome-coronavirus infection causes severe/lethal lung failure, and suggests treatment with recombinant ACE2 protein or other RAS modulators, i.e. AT1 receptor blocker.
-
(2005)
Nat Med
, vol.11
, pp. 875-879
-
-
Kuba, K.1
Imai, Y.2
Rao, S.3
-
21
-
-
21844460785
-
Angiotensin-converting enzyme 2 protects from severe acute lung failure
-
Imai Y, Kuba K, Rao S, et al. Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature 2005; 436:112-116.
-
(2005)
Nature
, vol.436
, pp. 112-116
-
-
Imai, Y.1
Kuba, K.2
Rao, S.3
-
22
-
-
0027968595
-
Evidence for direct local effect of angiotensin in vascular hypertrophy. in vivo gene transfer of angiotensin converting enzyme
-
Morishita R, Gibbons GH, Ellison KE, et al. Evidence for direct local effect of angiotensin in vascular hypertrophy. In vivo gene transfer of angiotensin converting enzyme. J Clin Invest 1994; 94:978-984.
-
(1994)
J Clin Invest
, vol.94
, pp. 978-984
-
-
Morishita, R.1
Gibbons, G.H.2
Ellison, K.E.3
-
23
-
-
4344600627
-
Mice with cardiac-restricted angiotensin-converting enzyme (ACE) have atrial enlargement, cardiac arrhythmia, and sudden death
-
Xiao HD, Fuchs S, Campbell DJ, et al. Mice with cardiac-restricted angiotensin-converting enzyme (ACE) have atrial enlargement, cardiac arrhythmia, and sudden death. Am J Pathol 2004; 165:1019-1032.
-
(2004)
Am J Pathol
, vol.165
, pp. 1019-1032
-
-
Xiao, H.D.1
Fuchs, S.2
Campbell, D.J.3
-
24
-
-
0029823037
-
Increased accumulation of tissue ACE in human atherosclerotic coronary artery disease
-
Diet F, Pratt RE, Berry GJ, et al. Increased accumulation of tissue ACE in human atherosclerotic coronary artery disease. Circulation 1996; 94:2756-2767.
-
(1996)
Circulation
, vol.94
, pp. 2756-2767
-
-
Diet, F.1
Pratt, R.E.2
Berry, G.J.3
-
25
-
-
0030659486
-
Enhanced expression of angiotensin-converting enzyme is associated with progression of coronary atherosclerosis in humans
-
Ohishi M, Ueda M, Rakugi H, et al. Enhanced expression of angiotensin-converting enzyme is associated with progression of coronary atherosclerosis in humans. J Hypertens 1997; 15:1295-1302.
-
(1997)
J Hypertens
, vol.15
, pp. 1295-1302
-
-
Ohishi, M.1
Ueda, M.2
Rakugi, H.3
-
26
-
-
0032983046
-
The tissue renin-angiotensin system in human pancreas
-
Tahmasebi M, Puddefoot JR, Inwang ER, et al. The tissue renin-angiotensin system in human pancreas. J Endocrinol 1999; 161:317-322.
-
(1999)
J Endocrinol
, vol.161
, pp. 317-322
-
-
Tahmasebi, M.1
Puddefoot, J.R.2
Inwang, E.R.3
-
27
-
-
0032898010
-
Expression and localization of the renin-angiotensin system in the rat pancreas
-
Leung PS, Chan WP, Wong TP, et al. Expression and localization of the renin-angiotensin system in the rat pancreas. J Endocrinol 1999; 160:13-19.
-
(1999)
J Endocrinol
, vol.160
, pp. 13-19
-
-
Leung, P.S.1
Chan, W.P.2
Wong, T.P.3
-
28
-
-
0034095811
-
Physiology and pathophysiology of the adipose tissue renin-angiotensin system
-
Engeli S, Negrel R, Sharma AM. Physiology and pathophysiology of the adipose tissue renin-angiotensin system. Hypertension 2000; 35:1270-1277.
-
(2000)
Hypertension
, vol.35
, pp. 1270-1277
-
-
Engeli, S.1
Negrel, R.2
Sharma, A.M.3
-
29
-
-
14644395574
-
Weight loss and the renin-angiotensin-aldosterone system
-
Engeli S, Bohnke J, Gorzelniak K, et al. Weight loss and the renin-angiotensin-aldosterone system. Hypertension 2005; 45:356-362.
-
(2005)
Hypertension
, vol.45
, pp. 356-362
-
-
Engeli, S.1
Bohnke, J.2
Gorzelniak, K.3
-
30
-
-
5044233892
-
Blockade of the renin-angiotensin system decreases adipocyte size with improvement in insulin sensitivity
-
Furuhashi M, Ura N, Takizawa H, et al. Blockade of the renin-angiotensin system decreases adipocyte size with improvement in insulin sensitivity. J Hypertens 2004; 22:1977-1982. A study showing a link between RAS blockade, adiponectin concentration and insulin resistance in patients with essential hypertension.
-
(2004)
J Hypertens
, vol.22
, pp. 1977-1982
-
-
Furuhashi, M.1
Ura, N.2
Takizawa, H.3
-
31
-
-
0038818552
-
Blockade of the renin-angiotensin system increases adiponectin concentrations in patients with essential hypertension
-
Furuhashi M, Ura N, Higashiura K, et al. Blockade of the renin-angiotensin system increases adiponectin concentrations in patients with essential hypertension. Hypertension 2003; 42:76-81.
-
(2003)
Hypertension
, vol.42
, pp. 76-81
-
-
Furuhashi, M.1
Ura, N.2
Higashiura, K.3
-
32
-
-
15944377334
-
2R) reduces adipose cell size and protects from diet-induced obesity and insulin resistance
-
2 receptor and supports its involvement in increasing the adipose cell mass and glucose intolerance.
-
(2005)
Diabetes
, vol.54
, pp. 991-999
-
-
Yvan-Charvet, L.1
Even, P.2
Bloch-Faure, M.3
-
33
-
-
0033824138
-
International Union of Pharmacology. XXIII. The angiotensin II receptors
-
de Gasparo M, Catt KJ, Inagami T, et al. International Union of Pharmacology. XXIII. The angiotensin II receptors. Pharmacol Rev 2000; 52:415-472.
-
(2000)
Pharmacol Rev
, vol.52
, pp. 415-472
-
-
Gasparo, M.1
Catt, K.J.2
Inagami, T.3
-
34
-
-
0027432809
-
Nuclear angiotensin receptors induce transcription of renin and angiotensinogen mRNA
-
Eggena P, Zhu JH, Clegg K, et al. Nuclear angiotensin receptors induce transcription of renin and angiotensinogen mRNA. Hypertension 1993; 22:496-501.
-
(1993)
Hypertension
, vol.22
, pp. 496-501
-
-
Eggena, P.1
Zhu, J.H.2
Clegg, K.3
-
35
-
-
0035824901
-
In vitro evidence for an intracellular site of angiotensin action
-
Cook JL, Zhang Z, Re RN. In vitro evidence for an intracellular site of angiotensin action. Circ Res 2001; 89:1138-1146.
-
(2001)
Circ Res
, vol.89
, pp. 1138-1146
-
-
Cook, J.L.1
Zhang, Z.2
Re, R.N.3
-
37
-
-
0034688194
-
Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients
-
The Heart Outcomes Prevention Evaluation Study Investigators
-
Yusuf S, Sleight P, Pogue J, et al. Effects of an angiotensin-converting- enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000; 342:145-153.
-
(2000)
N Engl J Med
, vol.342
, pp. 145-153
-
-
Yusuf, S.1
Sleight, P.2
Pogue, J.3
-
38
-
-
0029010357
-
Contribution of kinins to the cardiovascular actions of angiotensin-converting enzyme inhibitors
-
Linz W, Wiemer G, Gohlke P, et al. Contribution of kinins to the cardiovascular actions of angiotensin-converting enzyme inhibitors. Pharmacol Rev 1995; 47:25-49.
-
(1995)
Pharmacol Rev
, vol.47
, pp. 25-49
-
-
Linz, W.1
Wiemer, G.2
Gohlke, P.3
-
39
-
-
18844368834
-
Kallikrein-kinin in stroke, cardiovascular and renal disease
-
Chao J, Chao L. Kallikrein-kinin in stroke, cardiovascular and renal disease. Exp Physiol 2005; 90:291-298.
-
(2005)
Exp Physiol
, vol.90
, pp. 291-298
-
-
Chao, J.1
Chao, L.2
-
41
-
-
0032698983
-
Angiotensin II type 2 receptor overexpression activates the vascular kinin system and causes vasodilation
-
Tsutsumi Y, Matsubara H, Masaki H, et al. Angiotensin II type 2 receptor overexpression activates the vascular kinin system and causes vasodilation. J Clin Invest 1999; 104:925-935.
-
(1999)
J Clin Invest
, vol.104
, pp. 925-935
-
-
Tsutsumi, Y.1
Matsubara, H.2
Masaki, H.3
-
42
-
-
3042820768
-
2 receptors
-
2 receptors. Circ Res 2004; 94:1623-1629. An impressive study highlighting the complex interactions between RAS and the kallikrein-kinin system.
-
(2004)
Circ Res
, vol.94
, pp. 1623-1629
-
-
Bergaya, S.1
Hilgers, R.H.2
Meneton, P.3
-
44
-
-
0026075764
-
Ramiprilat enhances endothelial autacoid formation by inhibiting breakdown of endothelium-derived bradykinin
-
Wiemer G, Schölkens BA, Becker RHA, et al. Ramiprilat enhances endothelial autacoid formation by inhibiting breakdown of endothelium-derived bradykinin. Hypertension 1991; 18:558-563.
-
(1991)
Hypertension
, vol.18
, pp. 558-563
-
-
Wiemer, G.1
Schölkens, B.A.2
Becker, R.H.A.3
-
45
-
-
0033586646
-
Angiotensin-converting enzyme inhibitor ramiprilat interferes with the sequestration of the B2 kinin receptor within the plasma membrane of native endothelial cells
-
Benzing T, Fleming I, Blaukat A, et al. Angiotensin-converting enzyme inhibitor ramiprilat interferes with the sequestration of the B2 kinin receptor within the plasma membrane of native endothelial cells. Circulation 1999; 99:2034-2040.
-
(1999)
Circulation
, vol.99
, pp. 2034-2040
-
-
Benzing, T.1
Fleming, I.2
Blaukat, A.3
-
46
-
-
0037131193
-
CK2 phosphorylates the angiotensin-converting enzyme and regulates its retention in the endothelial cell plasma membrane
-
Kohlstedt K, Shoghi F, Müller-Esterl W, et al. CK2 phosphorylates the angiotensin-converting enzyme and regulates its retention in the endothelial cell plasma membrane. Circ Res 2002; 91:749-756.
-
(2002)
Circ Res
, vol.91
, pp. 749-756
-
-
Kohlstedt, K.1
Shoghi, F.2
Müller-Esterl, W.3
-
47
-
-
0347600924
-
Angiotensin-converting enzyme is involved in outside-in signalling in endothelial cells
-
See Ref. [48•]
-
Kohlstedt K, Brandes RP, Muller-Esterl W, et al. Angiotensin-converting enzyme is involved in outside-in signalling in endothelial cells. Circ Res 2004; 94:60-67. See Ref. [48•].
-
(2004)
Circ Res
, vol.94
, pp. 60-67
-
-
Kohlstedt, K.1
Brandes, R.P.2
Muller-Esterl, W.3
-
48
-
-
11244292347
-
Signaling via the angiotensin-converting enzyme enhances the expression of cyclooxygenase-2 in endothelial cells
-
Kohlstedt K, Busse R, Fleming I. Signaling via the angiotensin-converting enzyme enhances the expression of cyclooxygenase-2 in endothelial cells. Hypertension 2005; 45:126-132. Studies describing an ACE-dependent signalling pathway in endothelial cells that is activated by the binding of an ACE inhibitor to the enzyme.
-
(2005)
Hypertension
, vol.45
, pp. 126-132
-
-
Kohlstedt, K.1
Busse, R.2
Fleming, I.3
-
49
-
-
0035916235
-
Effects of ramipril and vitamin E on atherosclerosis: The study to evaluate carotid ultrasound changes in patients treated with ramipril and vitamin E (SECURE)
-
Lonn EM, Yusuf S, Dzavik V, et al. Effects of ramipril and vitamin E on atherosclerosis: the study to evaluate carotid ultrasound changes in patients treated with ramipril and vitamin E (SECURE). Circulation 2001; 103:919-925.
-
(2001)
Circulation
, vol.103
, pp. 919-925
-
-
Lonn, E.M.1
Yusuf, S.2
Dzavik, V.3
-
50
-
-
0035904369
-
Ramipril and the development of diabetes
-
Yusuf S, Gerstein H, Hoogwerf B, et al. Ramipril and the development of diabetes. JAMA 2001; 286:1882-1885.
-
(2001)
JAMA
, vol.286
, pp. 1882-1885
-
-
Yusuf, S.1
Gerstein, H.2
Hoogwerf, B.3
-
51
-
-
0035922441
-
Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
-
Brenner BM, Cooper ME, de Zeeuw D, et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001; 345:861-869.
-
(2001)
N Engl J Med
, vol.345
, pp. 861-869
-
-
Brenner, B.M.1
Cooper, M.E.2
De Zeeuw, D.3
-
52
-
-
0035922447
-
Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
-
Lewis EJ, Hunsicker LG, Clarke WR, et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001; 345:851-860.
-
(2001)
N Engl J Med
, vol.345
, pp. 851-860
-
-
Lewis, E.J.1
Hunsicker, L.G.2
Clarke, W.R.3
-
53
-
-
18844449196
-
Why blockade of the renin-angiotensin system reduces the incidence of new-onset diabetes
-
Jandeleit-Dahm KA, Tikellis C, Reid CM, et al. Why blockade of the renin-angiotensin system reduces the incidence of new-onset diabetes. J Hypertens 2005; 23:463-473. An informative review summarizing the antidiabetic actions of RAS inhibitors.
-
(2005)
J Hypertens
, vol.23
, pp. 463-473
-
-
Jandeleit-Dahm, K.A.1
Tikellis, C.2
Reid, C.M.3
-
54
-
-
10044221986
-
Enalapril attenuates angiotensin II-induced atherosclerosis and vascular inflammation
-
da Cunha V, Tham DM, Martin-McNulty B, et al. Enalapril attenuates angiotensin II-induced atherosclerosis and vascular inflammation. Atherosclerosis 2005; 178:9-17.
-
(2005)
Atherosclerosis
, vol.178
, pp. 9-17
-
-
Da Cunha, V.1
Tham, D.M.2
Martin-McNulty, B.3
-
55
-
-
1542547460
-
Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARγ-modulating activity
-
Benson SC, Pershadsingh HA, Ho CI, et al. Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARγ-modulating activity. Hypertension 2004; 43:993-1002. An interesting study that reports that some AT1 receptor antagonists act as partial agonists and exert effects on intracellular signalling/gene expression (PPARγ activation).
-
(2004)
Hypertension
, vol.43
, pp. 993-1002
-
-
Benson, S.C.1
Pershadsingh, H.A.2
Ho, C.I.3
-
56
-
-
2442451618
-
Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-γ activity
-
Schupp M, Janke J, Clasen R, et al. Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-γ activity. Circulation 2004; 109:2054-2057. A study (published at roughly the same time as Ref. [55•]} highlighting the ability of specific AT1 receptor antagonists to activate PPARγ activity in adipocytes.
-
(2004)
Circulation
, vol.109
, pp. 2054-2057
-
-
Schupp, M.1
Janke, J.2
Clasen, R.3
-
57
-
-
18744383954
-
Treating the metabolic syndrome: Telmisartan as a peroxisome proliferator-activated receptor-gamma activator
-
Kurtz TW. Treating the metabolic syndrome: telmisartan as a peroxisome proliferator-activated receptor-gamma activator. Acta Diabetologica 2005; 42 (Suppl. 1):s9-s16.
-
(2005)
Acta Diabetologica
, vol.42
, Issue.1 SUPPL.
-
-
Kurtz, T.W.1
-
58
-
-
4544333229
-
Renin-angiotensin system and angiotensin receptor blockers in the metabolic syndrome
-
Prasad A, Quyyumi AA. Renin-angiotensin system and angiotensin receptor blockers in the metabolic syndrome. Circulation 2004; 110:1507-1512. A well-written up-to-date review discussing the possibilities of RAS inhibition in metabolic syndrome.
-
(2004)
Circulation
, vol.110
, pp. 1507-1512
-
-
Prasad, A.1
Quyyumi, A.A.2
-
59
-
-
20344397446
-
Is angiotensin-II an endogenous pro-inflammatory molecule?
-
Das UN. Is angiotensin-II an endogenous pro-inflammatory molecule? Med Sci Monit 2005; 11:RA155-RA162. A review focusing on the induction of cytokines, nuclear factor kappa B and oxidative stress by angiotensin II, and discussing the anti-inflammatory actions of RAS inhibition.
-
(2005)
Med Sci Monit
, vol.11
-
-
Das, U.N.1
-
60
-
-
0035818501
-
Genetically increased angiotensin I-converting enzyme level and renal complications in the diabetic mouse
-
U S A
-
Huang W, Gallois Y, Bouby N, et al. Genetically increased angiotensin I-converting enzyme level and renal complications in the diabetic mouse. Proc Natl Acad Sci U S A 2001; 98:13330-13334.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 13330-13334
-
-
Huang, W.1
Gallois, Y.2
Bouby, N.3
-
61
-
-
15244340432
-
ACE gene titration in mice uncovers a new mechanism for ACE on the control of body weight
-
Heimann AS, Favarato MH, Gozzo FC, et al. ACE gene titration in mice uncovers a new mechanism for ACE on the control of body weight. Physiol Genomics 2005; 20:173-182. In-vivo evidence that ACE is involved in the regulation of body weight and fat accumulation, obtained from mice with one or more copies of ACE gene.
-
(2005)
Physiol Genomics
, vol.20
, pp. 173-182
-
-
Heimann, A.S.1
Favarato, M.H.2
Gozzo, F.C.3
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