Vasopressin-induced intracellular redistribution of protein kinase D in intestinal epithelial cells

Journal of Cellular Physiology

Volumn 196, Issue 3, 2003, Pages 483-492

  Rey, Osvaldo ^a   Zhukova, Elena ^a   Sinnett Smith, James ^a   Rozengurt, Enrique ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GREEN FLUORESCENT PROTEIN; PROTEIN KINASE; PROTEIN KINASE C; PROTEIN KINASE D; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG; VASOPRESSIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL STIMULATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; DYNAMICS; ENZYME ACTIVATION; INTESTINE EPITHELIUM CELL; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; SIGNAL TRANSDUCTION; STEADY STATE;

ANIMALS; CELL LINE; CELL MEMBRANE; CELL NUCLEUS; CYTOSOL; HETEROTRIMERIC GTP-BINDING PROTEINS; INTESTINAL MUCOSA; PROTEIN KINASE C; RATS; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; VASOPRESSINS;

EID: 0042769227     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.10323     Document Type: Article

References (66)

1. Bagowski CP, Stein-Gerlach M, Choidas A, Ullrich A. 1999. Cell-type specific phosphorylation of threonines T654 and T669 by PKD defines the signal capacity of the EGF receptor. EMBO J 18:5567-5576.
2. Ben-Levy R, Hooper S, Wilson R, Paterson HF, Marshall CJ. 1998. Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2. Curr Biol 8:1049-1057.
3. Bowden ET, Barth M, Thomas D, Glazer RI, Mueller SC. 1999. An invasion-related complex of cortactin, paxillin and PKCmu associates with invadopodia at sites of extracellular matrix degradation. Oncogene 18:4440-4449.
4. Brownawell AM, Kops GJ, Macara IG, Burgering BM. 2001. Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX. Mol Cell Biol 21:3534-3546.
5. Buchner K. 2000. The role of protein kinase C in the regulation of cell growth and in signalling to the cell nucleus. J Cancer Res Clin Oncol 126:1-11.
6. Burgess AW. 1998. Growth control mechanisms in normal and transformed intestinal cells. Philos Trans R Soc Lond B Biol Sci 353:903-909.
7. Chen RH, Sarnecki C, Blenis J. 1992. Nuclear localization and regulation of erk- and rsk-encoded protein kinases. Mol Cell Biol 12:915-927.
8. Chiu T, Rozengurt E. 2001. PKD in intestinal epithelial cells: Rapid activation by phorbol esters, LPA, and angiotensin through PKC. Am J Physiol Cell Physiol 280:C929-C942.
9. Chiu T, Wu SS, Santiskulvong C, Tangkijvanich P, Yee HF, Jr., Rozengurt E. 2002. Vasopressin-mediated mitogenic signaling in intestinal epithelial cells. Am J Physiol Cell Physiol 282:C434-C450.
10. Cyert MS. 2001. Regulation of nuclear localization during signaling. J Biol Chem 276:20805-20808.
11. Dignass AU, Podolsky DK. 1993. Cytokine modulation of intestinal epithelial cell restitution: Central role of transforming growth factor beta. Gastroenterology 105:1323-1332.
12. Fornerod M, Ohno M, Yoshida M, Mattaj IW. 1997. CRM1 is an export receptor for leucine-rich nuclear export signals. Cell 90:1051-1060.
13. Fukuda M, Gotoh Y, Nishida E. 1997. Interaction of MAP kinase with MAP kinase kinase: Its possible role in the control of nucleocytoplasmic transport of MAP kinase. EMBO J 16:1901-1908.
14. Gama-Carvalho M, Carmo-Fonseca M. 2001. The rules and roles of nucleocytoplasmic shuttling proteins. FEBS Lett 498:157-163.
15. Goke M, Kanai M, Podolsky DK. 1998. Intestinal fibroblasts regulate intestinal epithelial cell proliferation via hepatocyte growth factor. Am J Physiol 274:G809-G818.
16. Gonzalez FA, Seth A, Raden DL, Bowman DS, Fay FS, Davis RJ. 1993. Serum-induced translocation of mitogen-activated protein kinase to the cell surface ruffling membrane and the nucleus. J Cell Biol 122: 1089-1101.
17. Guha S, Rey O, Rozengurt E. 2002. Neurotensin induces protein kinase C-dependent protein kinase D activation and DNA synthesis in human pancreatic carcinoma cell line PANC-1. Cancer Res 62: 1632-1640.
18. Hurd C, Rozengurt E. 2001. Protein kinase D is sufficient to suppress EGF-induced c-Jun Ser 63 phosphorylation. Biochem Biophys Res Commun 282:404-408.
19. Hurd C, Waldron RT, Rozengurt E. 2002. Protein kinase D complexes with C-Jun N-terminal kinase via activation loop phosphorylation and phosphorylates the C-Jun N-terminus. Oncogene 21:2154-2160.
20. Iglesias T, Rozengurt E. 1998. Protein kinase D activation by mutations within its pleckstrin homology domain. J Biol Chem 273:410-416.
21. Iglesias T, Rozengurt E. 1999. Protein kinase D activation by deletion of its cysteine-rich motifs. FEBS Lett 454:53-56.
22. Iglesias T, Matthews S, Rozengurt E. 1998a. Dissimilar phorbol ester binding properties of the individual cysteine-rich motifs of protein kinase D. FEBS Lett 437:19-23.
23. Iglesias T, Waldron RT, Rozengurt E. 1998b. Identification of in vivo phosphorylation sites required for protein kinase D activation. J Biol Chem 273:27662-27667.
24. Jaken S. 1996. Protein kinase C isozymes and substrates. Curr Opin Cell Biol 8:168-173.
25. Jamora C, Yamanouye N, Van Lint J, Laudenslager J, Vandenheede JR, Faulkner DJ, Malhotra V. 1999. Gbetagamma-mediated regulation of Golgi organization is through the direct activation of protein kinase D. Cell 98:59-68.
26. Johannes FJ, Prestle J, Eis S, Oberhagemann P, Pfizenmaier K. 1994. PKCu is a novel, atypical member of the protein kinase C family. J Biol Chem 269:6140-6148.
27. Johannes FJ, Horn J, Link G, Haas E, Siemienski K, Wajant H, Pfizenmaier K. 1998. Protein kinase Cmu downregulation of tumor-necrosis-factor-induced apoptosis correlates with enhanced expression of nuclear-factor-kappaB-dependent protective genes. Eur J Biochem 257:47-54.
28. Kaffman A, O'Shea EK. 1999. Regulation of nuclear localization: A key to a door. Ann Rev Cell Dev Biol 15:291-339.
29. Kanai M, Mullen C, Podolsky DK. 1998. Intestinal trefoil factor induces inactivation of extracellular signal-regulated protein kinase in intestinal epithelial cells. Proc Natl Acad Sci USA 95:178-182.
30. Khokhlatchev AV, Canagarajah B, Wilsbacher J, Robinson M, Atkinson M, Goldsmith E, Cobb MH. 1998. Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation. Cell 93:605-615.
31. Lenormand P, Sardet C, Pagès G, L'Allemain G, Brunet A, Pouysségur J. 1993. Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts. J Cell Biol 122:1079-1088.
32. Lewis JM, Baskaran R, Taagepera S, Schwartz MA, Wang JY. 1996. Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic-nuclear transport. Proc Natl Acad Sci USA 93:15174-15179.
33. Liljedahl M, Maeda Y, Colanzi A, Ayala I, Van Lint J, Malhotra V. 2001. Protein kinase D regulates the fission of cell surface destined transport carriers from the trans-Golgi network. Cell 104:409-420.
34. Matthews SA, Pettit GR, Rozengurt E. 1997. Bryostatin 1 induces biphasic activation of protein kinase D in intact cells. J Biol Chem 272:20245-20250.
35. Matthews S, Iglesias T, Cantrell D, Rozengurt E. 1999. Dynamic redistribution of protein kinase D (PKD) as revealed by a GFP-PKD fusion protein: Dissociation from PKD activation. FEBS Lett 457: 515-521.
36. Matthews SA, Iglesias T, Rozengurt E, Cantrell D. 2000. Spatial and temporal regulation of protein kinase D (PKD). EMBO J 19:2935-2945.
37. Mohamed AJ, Vargas L, Nore BF, Backesjo CM, Christensson B, Smith CI. 2000. Nucleocytoplasmic shuttling of Bruton's tyrosine kinase. J Biol Chem 275:40614-40619.
38. Moriguchi T, Gotoh Y, Nishida E. 1996. Roles of the MAP kinase cascade in vertebrates. Adv Pharmacol 36:121-137.
39. Newton AC. 1997. Regulation of protein kinase C. Curr Opin Cell Biol 9:161-167.
40. Ossareh-Nazari B, Bachelerie F, Dargemont C. 1997. Evidence for a role of CRM1 in signal-mediated nuclear protein export. Science 278:141-144.
41. Perander M, Bjorkoy G, Johansen T. 2001. Nuclear import and export signals enable rapid nucleocytoplasmic shuttling of the atypical protein kinase C lambda. J Biol Chem 276:13015-13024.
42. Prestle J, Pfizenmaier K, Brenner J, Johannes FJ. 1996. Protein kinase C mu is located at the Golgi compartment. J Cell Biol 134: 1401-1410.
43. Quaroni A, Wands J, Trelstad RL, Isselbacher KJ. 1979. Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria. J Cell Biol 80:248-265.
44. Ray RM, Zimmerman BJ, McCormack SA, Patel TB, Johnson LR. 1999. Polyamine depletion arrests cell cycle and induces inhibitors p21(Waf1/Cip1), p27(Kip1), and p53 in IEC-6 cells. Am J Physiol 276:C684-C691.
45. Rey O, Rozengurt E. 2001. Protein kinase D interacts with Golgi via its Cysteine-rich domain. Biochem Biophys Res Commun 287:21-26.
46. Rey O, Sinnett-Smith J, Zhukova E, Rozengurt E. 2001a. Regulated nucleocytoplasmic transport of protein kinase D in response to G protein-coupled receptor activation. J Biol Chem 276:49228-49235.
47. Rey O, Young SH, Cantrell D, Rozengurt E. 2001b. Rapid protein kinase D translocation in response to G protein-coupled receptor activation: Dependence on protein kinase C. J Biol Chem 276: 32616-32626.
48. Rozengurt E. 1986. Early signals in the mitogenic response. Science 234:161-166.
49. Rozengurt E. 1998. Signal transduction pathways in the mitogenic response to G protein-coupled neuropeptide receptor agonists. J Cell Physiol 177:507-517.
50. Rozengurt E, Sinnett-Smith J, Zugaza JL. 1997. Protein kinase D: A novel target for diacylglycerol and phorbol esters. Biochem Soc Trans 25:565-571.
51. Santos MF, McCormack SA, Guo Z, Okolicany J, Zheng Y, Johnson LR, Tigyi G. 1997. Rho proteins play a critical role in cell migration during the early phase of mucosal restitution. J Clin Invest 100: 216-225.
52. Seufferlein T, Withers DJ, Mann D, Rozengurt E. 1996. Dissociation of mitogen-activated protein kinase activation from p125 focal adhesion kinase tyrosine phosphorylation in Swiss 3T3 cells stimulated by bombesin, lysophosphatidic acid, and platelet-derived growth factor. Mol Biol Cell 7:1865-1875.
53. Teruel MN, Meyer T. 2000. Translocation and reversible localization of signaling proteins: A dynamic future for signal transduction. Cell 103:181-184.
54. Ullman KS, Powers MA, Forbes DJ. 1997. Nuclear export receptors: From importin to exportin. Cell 90:967-970.
55. Valverde AM, Sinnett-Smith J, Van Lint J, Rozengurt E. 1994. Molecular cloning and characterization of protein kinase D: A target for diacylglycerol and phorbol esters with a distinctive catalytic domain. Proc Natl Acad Sci USA 91:8572-8576.
56. Van Lint JV, Sinnett-Smith J, Rozengurt E. 1995. Expression and characterization of PKD, a phorbol ester and diacylglycerol-stimulated serine protein kinase. J Biol Chem 270:1455-1461.
57. Waldron RT, Rozengurt E. 2003. Protein Kinase C Phosphorylates Protein Kinase D Activation Loop Ser744 and Ser748 and Releases Autoinhibition by the Pleckstrin Homology Domain. J Biol Chem 278:154-163.
58. Waldron RT, Iglesias T, Rozengurt E. 1999. The pleckstrin homology domain of protein kinase D interacts preferentially with the eta isoform of protein kinase C. J Biol Chem 274:9224-9230.
59. Waldron R, Rey O, Iglesis T, Tugal T, Cantrell D, Rozengurt E. 2001. Activation loop Ser744 and Ser748 in protein kinase D are transphosphorylated in vivo. J Biol Chem 276:32606-32615.
60. Wolff B, Sanglier JJ, Wang Y. 1997. Leptomycin B is an inhibitor of nuclear export: Inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA. Chem Biol 4:139-147.
61. 2+, PKC, and Rho kinase. Am J Physiol Cell Physiol 282:C1432-C1444.
62. Yuan J, Slice L, Walsh JH, Rozengurt E. 2000. Activation of protein kinase D by signaling through the alpha subunit of the heterotrimeric G protein G(q). J Biol Chem 275:2157-2164.
63. Yuan J, Slice LW, Gu J, Rozengurt E. 2002. Cooperation of Gq, Gi and G12/13 in protein kinase D activation and phosphorylation induced by lysophosphatidic acid. J Biol Chem 10:10.
64. Zhukova E, Sinnett-Smith J, Rozengurt E. 2001. Protein kinase D potentiates DNA synthesis and cell proliferation induced by bombesin, vasopressin or phorbol esters in Swiss 3Te cells. J Biol Chem 276:40298-40305.
65. Zugaza JL, Sinnett-Smith J, Van Lint J, Rozengurt E. 1996. Protein kinase D (PKD) activation in intact cells through a protein kinase C-dependent signal transduction pathway. EMBO J 15:6220-6230.
66. Zugaza JL, Waldron RT, Sinnett-Smith J, Rozengurt E. 1997. Bombesin, vasopressin, endothelin, bradykinin, and platelet-derived growth factor rapidly activate protein kinase D through a protein kinase C-dependent signal transduction pathway. J Biol Chem 272:23952-23960.