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Volumn 46, Issue 25, 2007, Pages 4786-4789

Direct and label-free detection of solid-phase-bound compounds by using surface-enhanced raman scattering microspectroscopy

Author keywords

Analytical methods; Raman spectroscopy; SERS (surface enhanced Raman scattering); Supramolecular chemistry

Indexed keywords

POLYSTYRENES; RAMAN SCATTERING; RAMAN SPECTROSCOPY; SUPRAMOLECULAR CHEMISTRY;

EID: 34347249195     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200605190     Document Type: Article
Times cited : (42)

References (40)
  • 1
    • 2942620235 scopus 로고    scopus 로고
    • For review articles on the use of combinatorial receptor libraries in supramolecular chemistry, see: a
    • For review articles on the use of combinatorial receptor libraries in supramolecular chemistry, see: a) N. Srinivasan, J. D. Kilburn, Curr. Opin. Chem. Biol. 2004, 8, 305-310;
    • (2004) Curr. Opin. Chem. Biol , vol.8 , pp. 305-310
    • Srinivasan, N.1    Kilburn, J.D.2
  • 8
    • 0028125003 scopus 로고
    • In some cases it was found, for example, that the tags attached to the substrate for the library screening actually interfere with the on-bead binding. For one illustrative example, see
    • In some cases it was found, for example, that the tags attached to the substrate for the library screening actually interfere with the on-bead binding. For one illustrative example, see: H. Wennemers, W. C. Still, Tetrahedron Lett. 1994, 35, 6413-6416.
    • (1994) Tetrahedron Lett , vol.35 , pp. 6413-6416
    • Wennemers, H.1    Still, W.C.2
  • 9
    • 0035358555 scopus 로고    scopus 로고
    • For reviews on the encoding and deconvolution of combinatorial libraries, see: a
    • For reviews on the encoding and deconvolution of combinatorial libraries, see: a) R. L. Affleck, Curr. Opin. Chem. Biol. 2001, 5, 257-263;
    • (2001) Curr. Opin. Chem. Biol , vol.5 , pp. 257-263
    • Affleck, R.L.1
  • 13
    • 0035241689 scopus 로고    scopus 로고
    • b) D. B. Kassel, Chem. Rev. 2001, 101, 255-267;
    • (2001) Chem. Rev , vol.101 , pp. 255-267
    • Kassel, D.B.1
  • 15
    • 30744451691 scopus 로고    scopus 로고
    • For a recent example of the limitations imposed by the need of a tagging strand ,see
    • For a recent example of the limitations imposed by the need of a tagging strand ,see: J. Shepherd, T. Gale, K. B. Jensen, J. D. Kilburn, Chem. Eur. J. 2006, 12, 713-720.
    • (2006) Chem. Eur. J , vol.12 , pp. 713-720
    • Shepherd, J.1    Gale, T.2    Jensen, K.B.3    Kilburn, J.D.4
  • 21
    • 0002904707 scopus 로고    scopus 로고
    • In some cases, compounds on a solid support have been directly detected if special diagnostic or marker vibrational bands from individual characteristic functional groups that do not normally contribute to the matrix were present within the compound: a D. E. Pivonka, J. Comb. Chem. 2000, 2, 33-38;
    • In some cases, compounds on a solid support have been directly detected if special diagnostic or marker vibrational bands from individual characteristic functional groups that do not normally contribute to the matrix were present within the compound: a) D. E. Pivonka, J. Comb. Chem. 2000, 2, 33-38;
  • 23
    • 0033600022 scopus 로고    scopus 로고
    • For a review on the use of optical spectroscopy in combinatorial chemistry, see
    • For a review on the use of optical spectroscopy in combinatorial chemistry, see: H.-U. Gremlich, Biotechnol. Bioeng. 1998, 61, 179-187.
    • (1998) Biotechnol. Bioeng , vol.61 , pp. 179-187
    • Gremlich, H.-U.1
  • 24
    • 0036797420 scopus 로고    scopus 로고
    • So far only solid-phase-bound nanoparticles have been used for the detection of analytes in solution technique of on-bead injection, M. J. A. Canada, A. R. Medina, J. Frank, B. Lendl, Analyst 2002, 127, 1365-1369
    • So far only solid-phase-bound nanoparticles have been used for the detection of analytes in solution (technique of on-bead injection): M. J. A. Canada, A. R. Medina, J. Frank, B. Lendl, Analyst 2002, 127, 1365-1369.
  • 28
    • 85149612390 scopus 로고    scopus 로고
    • Surface-Enhanced Raman Spectroscopy: Advancements and Applications: Z.-Q. Tian, J. Raman Spectrosc. 2005, 36, 466-470;
    • d) "Surface-Enhanced Raman Spectroscopy: Advancements and Applications": Z.-Q. Tian, J. Raman Spectrosc. 2005, 36, 466-470;
  • 29
    • 33947167075 scopus 로고    scopus 로고
    • Eds, L. F. Cohen, R. Brown, M. J. T. Milton, W. E. Smith, Royal Society of Chemistry, Cambridge
    • e) Surface Enhanced Raman Spectroscopy (Eds.: L. F. Cohen, R. Brown, M. J. T. Milton, W. E. Smith), Royal Society of Chemistry, Cambridge, 2006
    • (2006) Surface Enhanced Raman Spectroscopy
  • 30
    • 34347247887 scopus 로고    scopus 로고
    • (Faraday Discuss. 2006, 132);
    • (Faraday Discuss. 2006, 132);
  • 36
    • 33746310676 scopus 로고    scopus 로고
    • Angew. Chem. Int. Ed. 2006, 45, 4277-4281.
    • (2006) Chem. Int. Ed , vol.45 , pp. 4277-4281
    • Angew1
  • 37
    • 34347243378 scopus 로고    scopus 로고
    • This number is based on the following approximation: the laser focus is approximated by a cylindrical Vfocus, π r2 h) with a radius r (lateral) and a height h (axial, In our experiment, values of r, 2 μm and h, 20 μm are used, which represent an upper limit. The of a single bead (Vbead, 4/3 π r3) is calculated with a radius of r, 50 μm The absolute amount of compound 1 in the laser focus region is therefore given by Vfocus/V bead multiplied by the total absolute amount of receptor on an entire single bead (100 pm, which was approximately 50 femtomole. For the conventional Raman spectrum Figure 3, lower spectrum, a 20 mM solution was placed in a cubic cuvette of 5-mm height, and a laser of approximately 1-mm radius was used for probing an absolute number of about 300 nmole of 1
    • 7 smaller than in solution.
  • 38
    • 34347243742 scopus 로고    scopus 로고
    • A statistical analysis of 36 spectra showed that after baseline correction and normalization the mean relative standard deviation (RSD) was only 10% (for more details see the Supporting Information).
    • A statistical analysis of 36 spectra showed that after baseline correction and normalization the mean relative standard deviation (RSD) was only 10% (for more details see the Supporting Information).
  • 39
    • 0042977275 scopus 로고    scopus 로고
    • As the experimental time in mapping approaches for Raman microspectroscopy critically depends on the number of spatially resolved measurements, very short acquisition times per individual Raman or SERS spectrum become crucial to an efficient implementation: S. Schlücker, M. D. Schaeberle, S. W. Huffman, I. W. Levin, Anal. Chem. 2003, 75, 4312-4318
    • As the experimental time in mapping approaches for Raman microspectroscopy critically depends on the number of spatially resolved measurements, very short acquisition times per individual Raman or SERS spectrum become crucial to an efficient implementation: S. Schlücker, M. D. Schaeberle, S. W. Huffman, I. W. Levin, Anal. Chem. 2003, 75, 4312-4318.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.