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Synthesis and evaluation of 1,4-benzodiazepine libraries
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Edited by Abelson JN. New York: Academic Press
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Bunin BA, Plunkett WJ, Ellman JA: Synthesis and evaluation of 1,4-benzodiazepine libraries. In Methods Enzymol. Edited by Abelson JN. New York: Academic Press; 1996, 267:448-465.
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Methods Enzymol
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Bunin, B.A.1
Plunkett, W.J.2
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0000074870
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Strategy and tactics in combinatorial organic synthesis. Applications to drug discovery
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Gordon EM, Gallop MA, Patel DV: Strategy and tactics in combinatorial organic synthesis. Applications to drug discovery. Accounts Chem Res 1996, 29:144-154.
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Accounts Chem Res
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Gordon, E.M.1
Gallop, M.A.2
Patel, D.V.3
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3
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0030477258
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Combinatorial synthesis of small organic molecules
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Balkenhohl F, Vondembusschehunnefeld C, Lansky A, Zechel C: Combinatorial synthesis of small organic molecules. Angew Chem Int Ed 1996, 35:2289-2337.
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Angew Chem Int Ed
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Balkenhohl, F.1
Vondembusschehunnefeld, C.2
Lansky, A.3
Zechel, C.4
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4
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0029065615
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Combinatorial synthesis. the design of compound libraries and their application to drug discovery
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Terrett NK, Gardner M, Gordon DW, Kobylecki RJ, Steele J: Combinatorial synthesis. The design of compound libraries and their application to drug discovery. Tetrahedron 1995, 51:8135-8173.
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Tetrahedron
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Terrett, N.K.1
Gardner, M.2
Gordon, D.W.3
Kobylecki, R.J.4
Steele, J.5
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5
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0000577984
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The 'one-bead-one-compound' combinatorial library method
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Lam KS, Lebl M, Krchnak V: The 'one-bead-one-compound' combinatorial library method. Chem Rev 1997, 97:411-448.
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Chem Rev
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Lam, K.S.1
Lebl, M.2
Krchnak, V.3
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6
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33748844784
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Combinatorial libraries: Studies in molecular recognition and the quest for new catalysts
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Gennari C, Nestler HP, Piarulli U, Salom B: Combinatorial libraries: studies in molecular recognition and the quest for new catalysts. Liebigs Ann-Recl 1997, 637-647. This review describes the two main combinatorial approaches for the sludy of host-guest interactions and summarises recent reports on catalytic systems developed using combinatorial strategies.
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Liebigs Ann-Recl
, pp. 637-647
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Gennari, C.1
Nestler, H.P.2
Piarulli, U.3
Salom, B.4
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7
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0029829698
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Recent advances at the interface of medicinal and combinatorial chemistry. Views on methodologies for the generation and evaluation of diversity and application to molecular recognition and catalysis
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Fenniri H: Recent advances at the interface of medicinal and combinatorial chemistry. Views on methodologies for the generation and evaluation of diversity and application to molecular recognition and catalysis. Curr Med Chem 1996, 3:343-378. This excellent review gives a brief account on the application of combinatorial chemistry to molecular recognition and catalysis.
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Curr Med Chem
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Fenniri, H.1
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8
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0029791484
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Sequence-selective receptors of peptides. A simple molecular design for construction of large combinatorial libraries of receptors
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Shao YF, Still WC: Sequence-selective receptors of peptides. A simple molecular design for construction of large combinatorial libraries of receptors. J Org Chem 1996, 61:6066-6087.
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J Org Chem
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Shao, Y.F.1
Still, W.C.2
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9
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0030854052
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Simple synthetic receptors that bind peptides in water
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Torneiro M, Still WC: Simple synthetic receptors that bind peptides in water. Tetrahedron 1997, 53:8739-8750.
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Tetrahedron
, vol.53
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Torneiro, M.1
Still, W.C.2
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10
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0001597672
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Simple structural requirements for sequence-selective peptide receptors? Tripeptide binding by a podand ionophore
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Burger MT, Still WC: Simple structural requirements for sequence-selective peptide receptors? Tripeptide binding by a podand ionophore. J Org Chem 1997, 62:4785-4790.
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J Org Chem
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Burger, M.T.1
Still, W.C.2
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11
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2842605870
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Discovery of sequence-selective peptide binding by synthetic receptors using encoded combinatorial libraries
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Still WC: Discovery of sequence-selective peptide binding by synthetic receptors using encoded combinatorial libraries. Accounts Chem Res 1996, 29:155-163.
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Accounts Chem Res
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Still, W.C.1
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12
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0030569403
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Synthetic receptors based on peptidosulfonamide peptidomimetics
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Lowik DWPM, Mulders SJE, Cheng Y, Shao YF, Liskamp RMJ: Synthetic receptors based on peptidosulfonamide peptidomimetics. Tetrahedron Lett 1996, 37:8253-8256.
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Tetrahedron Lett
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Lowik, D.W.P.M.1
Mulders, S.J.E.2
Cheng, Y.3
Shao, Y.F.4
Liskamp, R.M.J.5
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13
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0030021370
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A new application of a peptide library to identify selective interaction between small peptides in an attempt to develop recognition molecules toward protein surfaces
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Sasaki S, Takagi M, Tanaka Y, Maeda M: A new application of a peptide library to identify selective interaction between small peptides in an attempt to develop recognition molecules toward protein surfaces. Tetrahedron Lett 1996, 37:85-88.
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Tetrahedron Lett
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Sasaki, S.1
Takagi, M.2
Tanaka, Y.3
Maeda, M.4
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14
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0029924806
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Microautoradiographic identification of receptor-ligand interactions in bead-supported combinatorial libraries
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Nestler HP, Wennemers H, Sherlock R, Dong DLY: Microautoradiographic identification of receptor-ligand interactions in bead-supported combinatorial libraries. Bioorg Med Chem Lett 1996, 6:1327-1330.
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Bioorg Med Chem Lett
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Nestler, H.P.1
Wennemers, H.2
Sherlock, R.3
Dly, D.4
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15
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0028100318
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Peptidosteroidal receptors for opioid-peptides. Sequence-selective binding using a synthetic receptor library
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Boyce R, Li G, Nestler HP, Suenaga T, Still WC: Peptidosteroidal receptors for opioid-peptides. Sequence-selective binding using a synthetic receptor library. J Am Chem Soc 1994, 116:7955-7956.
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J Am Chem Soc
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Boyce, R.1
Li, G.2
Nestler, H.P.3
Suenaga, T.4
Still, W.C.5
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16
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0027362628
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Complex synthetic chemical libraries indexed with molecular tags
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Ohlmeyer MHJ, Swanson RN, Dillard LW, Reader JC, Asouline G, Kobayashi R, Wigler M, Still WC: Complex synthetic chemical libraries indexed with molecular tags. Proc Natl Acad Sci USA 1993, 90:10922-10926.
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Proc Natl Acad Sci USA
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Ohlmeyer, M.H.J.1
Swanson, R.N.2
Dillard, L.W.3
Reader, J.C.4
Asouline, G.5
Kobayashi, R.6
Wigler, M.7
Still, W.C.8
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17
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0029925955
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Sequence-selective peptide binding with a peptido-A,B-trans-steroidal receptor selected from an encoded combinatorial receptor library
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Cheng YA, Suenaga T, Still WC: Sequence-selective peptide binding with a peptido-A,B-trans-steroidal receptor selected from an encoded combinatorial receptor library. J Am Chem Soc 1996, 118:1813-1814. The more rigid peptidosteroid library described in this publication displayed increased selectivity compared with the earlier more flexible analogue.
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J Am Chem Soc
, vol.118
, pp. 1813-1814
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Cheng, Y.A.1
Suenaga, T.2
Still, W.C.3
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18
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0030253017
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Sequence-selective nonmacrocyclic two-armed receptors for peptides
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Nestler HP: Sequence-selective nonmacrocyclic two-armed receptors for peptides. Mol Divers 1996, 2:35-40. Highly flexible molecular forceps, based on a pentamethylene backbone, showed some selective binding to small peptides, but both binding strength and specificity were much lower than in cases involving cholic acid scaffolds. These studies demonstrated that some rigidity must be incorporated into the design of this type of receptor.
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Mol Divers
, vol.2
, pp. 35-40
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Nestler, H.P.1
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19
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0030598080
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The solid-phase synthesis of a guanidinium based tweezer receptor
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Bonnat M, Bradley M, Kilburn JD: The solid-phase synthesis of a guanidinium based tweezer receptor. Tetrahedron Lett 1996, 37:5409-5412.
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Tetrahedron Lett
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Bonnat, M.1
Bradley, M.2
Kilburn, J.D.3
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20
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4243092100
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Formation of artificial receptors by metal-templated self-assembly
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Linton B, Hamilton AD: Formation of artificial receptors by metal-templated self-assembly. Chem Rev 1997, 97:1669-1680. This review gives an excellent account of the metal-templated approach to the formation of artificial receptors, including the generation of libraries of these by parallel synthesis.
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Chem Rev
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Linton, B.1
Hamilton, A.D.2
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21
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0028784074
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A combinatorial library approach to artificial receptor design
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Goodman MS, Jubian V, Linton B, Hamilton AD: A combinatorial library approach to artificial receptor design. J Am Chem Soc 1995, 117:11610-11611.
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J Am Chem Soc
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Goodman, M.S.1
Jubian, V.2
Linton, B.3
Hamilton, A.D.4
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22
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0029825038
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Cyclopeptide libraries as new chiral selectors in capillary electrophoresis
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Jung G, Hofsetter H, Feiertag S, Stoll D, Hofsetter O, Wiesmuller KH, Schurig V: Cyclopeptide libraries as new chiral selectors in capillary electrophoresis. Angew Chem Int Ed 1996, 35:2148-2151. A useful application of combinatorial receptor libraries in chromatography has been demonstrated in this paper. The separation of amino acid enantiomers by capillary electrophoresis can be achieved when the peptide library is added to the mobile phase.
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(1996)
Angew Chem Int Ed
, vol.35
, pp. 2148-2151
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Jung, G.1
Hofsetter, H.2
Feiertag, S.3
Stoll, D.4
Hofsetter, O.5
Wiesmuller, K.H.6
Schurig, V.7
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24
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0029811207
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Combinatorial approach to the discovery of novel coordination complexes
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Francis MB, Finney NS, Jacobsen EN: Combinatorial approach to the discovery of novel coordination complexes. J Am Chem Soc 1996, 118:8983-8984. A new approach for the design of transition-metal receptors without predefined binding sites was put to the test. Using some conformational restrictions (turn-inducing building blocks) on the polymer-bound peptides, as well as a diversity of functionalities, led to a successful demonstration of this strategy.
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(1996)
J Am Chem Soc
, vol.118
, pp. 8983-8984
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Francis, M.B.1
Finney, N.S.2
Jacobsen, E.N.3
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25
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0031528847
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Selection approaches to catalytic systems
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Brady PA, Sanders JKM: Selection approaches to catalytic systems. Chem Soc Rev 1997, 26:327-336. This is an extensive review on all the selection approaches to catalysis, that is, on the recent progress in the fields of catalytic antibodies, ribozymes, imprinted polymers, combinatorial chemistry and thermodynamic templating.
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Chem Soc Rev
, vol.26
, pp. 327-336
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Brady, P.A.1
Sanders, J.K.M.2
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26
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0030846416
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Building thermodynamic combinatorial libraries of quinine macrocycles
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Rowan SJ, Sanders JKM: Building thermodynamic combinatorial libraries of quinine macrocycles. Chem Commun 1997:1407-1408. The generation of dynamic libraries of macrocyclic receptors by thermodynamically controlled reaction of different building blocks is described here and has opened the way to the possibility of a new selection approach to catalysis.
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Chem Commun
, pp. 1407-1408
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Rowan, S.J.1
Sanders, J.K.M.2
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27
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0029818124
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Structure-directed synthesis under thermodynamic control. Macrocyclic trimers from cinchona alkaloids
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Rowan SJ, Brady PA, Sanders JKM: Structure-directed synthesis under thermodynamic control. Macrocyclic trimers from cinchona alkaloids. Angew Chem Int Ed 1996, 35:2143-2145.
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Angew Chem Int Ed
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Rowan, S.J.1
Brady, P.A.2
Sanders, J.K.M.3
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28
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0031035389
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Use of molecular recognition to drive chemical evolution .1. Controlling the composition of an equilibrating mixture of simple arginine receptors
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Eliseev AV, Nelen MI: Use of molecular recognition to drive chemical evolution .1. Controlling the composition of an equilibrating mixture of simple arginine receptors. J Am Chem Soc 1997, 119:1147-1148.
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J Am Chem Soc
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Eliseev, A.V.1
Nelen, M.I.2
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29
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0030898702
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Virtual combinatorial libraries: Dynamic generation of molecular and supramolecular diversity by self-assembly
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Huc I, Lehn JM: Virtual combinatorial libraries: Dynamic generation of molecular and supramolecular diversity by self-assembly. Proc Natl Acad Sci USA 1997, 94:2106-2110. A dynamic inhibitor library was successfully generated. In the presence of a biological receptor, the formation of some components in the mixture was favoured over formation of others.
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Proc Natl Acad Sci USA
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, pp. 2106-2110
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Huc, I.1
Lehn, J.M.2
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30
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0030819668
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Generation of novel DNA-binding compounds by selection and amplification from self-assembled combinatorial libraries
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Klekota B, Hammond MH, Miller BL: Generation of novel DNA-binding compounds by selection and amplification from self-assembled combinatorial libraries. Tetrahedron Lett 1997, 38:8639-8642.
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Tetrahedron Lett
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Klekota, B.1
Hammond, M.H.2
Miller, B.L.3
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