Disentangling conformational states of macromolecules in 3D-EM through likelihood optimization

Nature Methods

Volumn 4, Issue 1, 2007, Pages 27-29

  Scheres, Sjors H W ^a   Gao, Haixiao ^b   Valle, Mikel ^a,e   Herman, Gabor T ^c   Eggermont, Paul P B ^d   Frank, Joachim ^b   Carazo, Jose Maria ^a  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c CITY UNIVERSITY OF NEW YORK   (United States)

^d UNIVERSITY OF DELAWARE   (United States)

^e CIC BIOGUNE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS T ANTIGEN;

ARTICLE; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; ELECTRON MICROSCOPY; ESCHERICHIA COLI; INTERMETHOD COMPARISON; MACROMOLECULE; MAXIMUM LIKELIHOOD METHOD; MOLECULAR IMAGING; NONHUMAN; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTEIN CONFORMATION; RIBOSOME; SIMIAN VIRUS 40; THREE DIMENSIONAL IMAGING;

ANTIGENS, POLYOMAVIRUS TRANSFORMING; ESCHERICHIA COLI; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; LIKELIHOOD FUNCTIONS; MICROSCOPY, ELECTRON; MODELS, MOLECULAR; PROTEIN CONFORMATION; RIBOSOMES; SENSITIVITY AND SPECIFICITY; SIMIAN VIRUS 40;

ESCHERICHIA COLI; SIMIAN VIRUS 40;

EID: 33845939047     PISSN: 15487091     EISSN: 15491676     Source Type: Journal    
DOI: 10.1038/nmeth992     Document Type: Article

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