메뉴 건너뛰기




Volumn 144, Issue 4, 2007, Pages 508-516

Candidate gene association study of insulin signaling genes and Alzheimer's disease: Evidence for SOS2, PCK1, and PPARγ as susceptibility loci

Author keywords

Association; Genetics; Late onset Alzheimer's disease; Type II diabetes

Indexed keywords

INSULIN;

EID: 34250873382     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.30503     Document Type: Article
Times cited : (51)

References (46)
  • 2
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • Barrett JC, Fry B, Maller J, Daly MJ. 2005. Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics 21(2):263-265.
    • (2005) Bioinformatics , vol.21 , Issue.2 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 5
    • 1842523229 scopus 로고    scopus 로고
    • Disregulated glyceroneogenesis: PCK1 as a candidate diabetes and obesity gene
    • Beale EG, Hammer RF, Antoine B, Forest C. 2004. Disregulated glyceroneogenesis: PCK1 as a candidate diabetes and obesity gene. Trends Endocrinol Metab 15(3):129-135.
    • (2004) Trends Endocrinol Metab , vol.15 , Issue.3 , pp. 129-135
    • Beale, E.G.1    Hammer, R.F.2    Antoine, B.3    Forest, C.4
  • 6
    • 0035829361 scopus 로고    scopus 로고
    • Controlling the false discovery rate in behavior genetics research
    • Benjamini Y, Drai D, Elmer G, Kafkafi N, Golani I. 2001. Controlling the false discovery rate in behavior genetics research. Behav Brain Res 125(1-2):279-284.
    • (2001) Behav Brain Res , vol.125 , Issue.1-2 , pp. 279-284
    • Benjamini, Y.1    Drai, D.2    Elmer, G.3    Kafkafi, N.4    Golani, I.5
  • 7
    • 13644260454 scopus 로고    scopus 로고
    • Nuclear receptor peroxisome proliferator-activated receptor-gamma is activated in rat microglial cells by the anti-inflammatory drug HCT1026, a derivative of flurbiprofen
    • Bernardo A, Ajmone-Cat MA, Gasparini L, Ongini E, Minghetti L. 2005. Nuclear receptor peroxisome proliferator-activated receptor-gamma is activated in rat microglial cells by the anti-inflammatory drug HCT1026, a derivative of flurbiprofen. J Neurochem 92(4):895-903.
    • (2005) J Neurochem , vol.92 , Issue.4 , pp. 895-903
    • Bernardo, A.1    Ajmone-Cat, M.A.2    Gasparini, L.3    Ongini, E.4    Minghetti, L.5
  • 11
    • 1242316296 scopus 로고    scopus 로고
    • Insulin and neurodegenerative disease: Shared and specific mechanisms
    • Craft S, Watson GS. 2004. Insulin and neurodegenerative disease: Shared and specific mechanisms. Lancet Neurol 3(3):169-178.
    • (2004) Lancet Neurol , vol.3 , Issue.3 , pp. 169-178
    • Craft, S.1    Watson, G.S.2
  • 13
    • 0031595923 scopus 로고    scopus 로고
    • A Pro12Ala substitution in PPAR gamma 2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
    • Deeb SS, Fajas L, Nemoto M, Pihlajamaki J, Mykkanen L, Kuusisto J, Laakso M, Fujimoto W, Auwerx J. 1998. A Pro12Ala substitution in PPAR gamma 2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nat Genet 20(3):284-287.
    • (1998) Nat Genet , vol.20 , Issue.3 , pp. 284-287
    • Deeb, S.S.1    Fajas, L.2    Nemoto, M.3    Pihlajamaki, J.4    Mykkanen, L.5    Kuusisto, J.6    Laakso, M.7    Fujimoto, W.8    Auwerx, J.9
  • 14
    • 0038519618 scopus 로고    scopus 로고
    • Insulin degrading enzyme (IDE) genetic variants and risk of Alzheimer's disease: Evidence of effect modification by apolipoprotein E (APOE)
    • Edland SD, Vriese FWD, Compton D, Smith GE, Ivnik R, Boeve BF, Tangalos EG, Petersen RC. 2003. Insulin degrading enzyme (IDE) genetic variants and risk of Alzheimer's disease: Evidence of effect modification by apolipoprotein E (APOE). Neurosci Lett 345(1):21-24.
    • (2003) Neurosci Lett , vol.345 , Issue.1 , pp. 21-24
    • Edland, S.D.1    Vriese, F.W.D.2    Compton, D.3    Smith, G.E.4    Ivnik, R.5    Boeve, B.F.6    Tangalos, E.G.7    Petersen, R.C.8
  • 16
    • 0242524453 scopus 로고    scopus 로고
    • The inheritebasis odiabetes mellitus: Implications for the genetic analysis of complex traits
    • Florez JC, Hirschhorn J, Altshuler D. 2003. The inheritebasis odiabetes mellitus: Implications for the genetic analysis of complex traits. Ann Rev Genomics Hum Genet 4:257-291.
    • (2003) Ann Rev Genomics Hum Genet , vol.4 , pp. 257-291
    • Florez, J.C.1    Hirschhorn, J.2    Altshuler, D.3
  • 18
    • 34250819754 scopus 로고    scopus 로고
    • Power of multifactor dimensionality reduction (MDR) for identifying gene-gene and gene-environment interactions
    • Hahn LW, Ritchie MD, Moore JH. 2001. Power of multifactor dimensionality reduction (MDR) for identifying gene-gene and gene-environment interactions. Am J Hum Genet 69(4):1174.
    • (2001) Am J Hum Genet , vol.69 , Issue.4 , pp. 1174
    • Hahn, L.W.1    Ritchie, M.D.2    Moore, J.H.3
  • 19
    • 33646401564 scopus 로고    scopus 로고
    • Hamilton G, Samedi F, Knight J, Archer N, Foy C, Walter S, Turic D, Jehu L, Moore P, Hollingworth P, et al. 2006. Polymorphisms in the phosphate and tensin homolog gene are not associated with late-onset Alzheimer's disease. Neurosci Lett 401(1-2):77-80.
    • Hamilton G, Samedi F, Knight J, Archer N, Foy C, Walter S, Turic D, Jehu L, Moore P, Hollingworth P, et al. 2006. Polymorphisms in the phosphate and tensin homolog gene are not associated with late-onset Alzheimer's disease. Neurosci Lett 401(1-2):77-80.
  • 20
    • 0036170755 scopus 로고    scopus 로고
    • Insulin resistance is attenuated in women with polycystic ovary syndrome with the Pro(12)Ala polymorphism in the PPAR gamma gene
    • Hara M, Alcoser SY, Qaadir A, Beiswenger KK, Cox NJ, Ehrmann DA. 2002. Insulin resistance is attenuated in women with polycystic ovary syndrome with the Pro(12)Ala polymorphism in the PPAR gamma gene. J Clin Endocrinol Metab 87(2):772-775.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.2 , pp. 772-775
    • Hara, M.1    Alcoser, S.Y.2    Qaadir, A.3    Beiswenger, K.K.4    Cox, N.J.5    Ehrmann, D.A.6
  • 23
    • 0025257612 scopus 로고
    • Restriction isotyping of human apolipoprotein-E by gene amplification and cleavage with Hhai
    • Hixson JE, Vernier DT. 1990. Restriction isotyping of human apolipoprotein-E by gene amplification and cleavage with Hhai. J Lipid Res 31(3):545-548.
    • (1990) J Lipid Res , vol.31 , Issue.3 , pp. 545-548
    • Hixson, J.E.1    Vernier, D.T.2
  • 24
    • 1842785179 scopus 로고    scopus 로고
    • Glucose metabolism and insulin receptor signal transduction in Alzheimer disease
    • Hoyer S. 2004. Glucose metabolism and insulin receptor signal transduction in Alzheimer disease. Eur J Pharmacol 490(1-3):115-125.
    • (2004) Eur J Pharmacol , vol.490 , Issue.1-3 , pp. 115-125
    • Hoyer, S.1
  • 26
    • 13644271368 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma is expressed in hippocampal neurons and its activation prevents beta-amyloid neurodegeneration: Role of Wnt signaling
    • Inestrosa NC, Godoy JA, Quintanilla RA, Koenig CS, Bronfman M. 2005. Peroxisome proliferator-activated receptor gamma is expressed in hippocampal neurons and its activation prevents beta-amyloid neurodegeneration: Role of Wnt signaling. Exp Cell Res 304(1):91-104.
    • (2005) Exp Cell Res , vol.304 , Issue.1 , pp. 91-104
    • Inestrosa, N.C.1    Godoy, J.A.2    Quintanilla, R.A.3    Koenig, C.S.4    Bronfman, M.5
  • 27
    • 13844270858 scopus 로고    scopus 로고
    • The effects of rosiglitazone and metformin on the plasma concentrations of resistin in patients with type 2 diabetes mellitus
    • Jung HS, Youn BS, Cho YM, Yu KY, Park HJ, Shin CS, Kim SY, Lee HK, Park KS. 2005. The effects of rosiglitazone and metformin on the plasma concentrations of resistin in patients with type 2 diabetes mellitus. Metabolism 54(3):314-320.
    • (2005) Metabolism , vol.54 , Issue.3 , pp. 314-320
    • Jung, H.S.1    Youn, B.S.2    Cho, Y.M.3    Yu, K.Y.4    Park, H.J.5    Shin, C.S.6    Kim, S.Y.7    Lee, H.K.8    Park, K.S.9
  • 28
    • 9844229370 scopus 로고    scopus 로고
    • Association between features of the insulin resistance syndrome and Alzheimer's disease independently of apolipoprotein E4 phenotype: Cross sectional population based study
    • Kuusisto J, Koivisto K, Mykkanen L, Helkala EL, Vanhanen M, Hanninen T, Kervinen K, Kesaniemi YA, Riekkinen PJ, Laakso M. 1997. Association between features of the insulin resistance syndrome and Alzheimer's disease independently of apolipoprotein E4 phenotype: Cross sectional population based study. Br Med J 315(7115):1045-1049.
    • (1997) Br Med J , vol.315 , Issue.7115 , pp. 1045-1049
    • Kuusisto, J.1    Koivisto, K.2    Mykkanen, L.3    Helkala, E.L.4    Vanhanen, M.5    Hanninen, T.6    Kervinen, K.7    Kesaniemi, Y.A.8    Riekkinen, P.J.9    Laakso, M.10
  • 29
    • 0021205247 scopus 로고
    • STATCALC - and integrated statistics system for the Apple-II microcomputer
    • Lee AJ, McInerney PJ, Mullins PR. 1984. STATCALC - and integrated statistics system for the Apple-II microcomputer. Comput Programs Biomed 18(3):265-272.
    • (1984) Comput Programs Biomed , vol.18 , Issue.3 , pp. 265-272
    • Lee, A.J.1    McInerney, P.J.2    Mullins, P.R.3
  • 30
    • 0037900979 scopus 로고    scopus 로고
    • Minireview: Lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors
    • Lee CH, Olson P, Evans RM. 2003. Minireview: Lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors. Endocrinology 144(6):2201-2207.
    • (2003) Endocrinology , vol.144 , Issue.6 , pp. 2201-2207
    • Lee, C.H.1    Olson, P.2    Evans, R.M.3
  • 31
    • 7244232742 scopus 로고    scopus 로고
    • Regulating the balance between peroxisome proliferator-activated receptor gamma and beta-catenin signaling during adipogenesis - A glycogen synthase kinase 3 beta phosphorylation-defective mutant of beta-catenin inhibits expression of a subset of adipogenic genes
    • Liu JJ, Farmer SR. 2004. Regulating the balance between peroxisome proliferator-activated receptor gamma and beta-catenin signaling during adipogenesis - A glycogen synthase kinase 3 beta phosphorylation-defective mutant of beta-catenin inhibits expression of a subset of adipogenic genes. J Biol Chem 279(43):45020-45027.
    • (2004) J Biol Chem , vol.279 , Issue.43 , pp. 45020-45027
    • Liu, J.J.1    Farmer, S.R.2
  • 34
    • 0036227542 scopus 로고    scopus 로고
    • Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies - The Honolulu-Asia Aging Study
    • Peila R, Rodriguez BL, Launer LJ. 2002. Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies - The Honolulu-Asia Aging Study. Diabetes 51(4):1256-1262.
    • (2002) Diabetes , vol.51 , Issue.4 , pp. 1256-1262
    • Peila, R.1    Rodriguez, B.L.2    Launer, L.J.3
  • 35
    • 27844525503 scopus 로고    scopus 로고
    • Monogenic syndromes of abnormal glucose homeostasis: Clinical review and relevance to the understanding of the pathology of insulin resistance and beta cell failure
    • Porter JR, Barrett TG. 2005. Monogenic syndromes of abnormal glucose homeostasis: Clinical review and relevance to the understanding of the pathology of insulin resistance and beta cell failure. J Med Genet 42(12):893-902.
    • (2005) J Med Genet , vol.42 , Issue.12 , pp. 893-902
    • Porter, J.R.1    Barrett, T.G.2
  • 37
    • 12244264435 scopus 로고    scopus 로고
    • Genetic power calculator: Design of linkage and association genetic mapping studies of complex traits
    • Purcell S, Cherny SS, Sham PC. 2003. Genetic power calculator: Design of linkage and association genetic mapping studies of complex traits. Bioinformatics 19(1):149-150.
    • (2003) Bioinformatics , vol.19 , Issue.1 , pp. 149-150
    • Purcell, S.1    Cherny, S.S.2    Sham, P.C.3
  • 41
    • 0033664539 scopus 로고    scopus 로고
    • Insulin receptors and insulin action in the brain: Review and clinical implications
    • Schulingkamp RJ, Pagano TC, Hung D, Raffa RB. 2000. Insulin receptors and insulin action in the brain: Review and clinical implications. Neurosci Biobehav Rev 24(8):855-872.
    • (2000) Neurosci Biobehav Rev , vol.24 , Issue.8 , pp. 855-872
    • Schulingkamp, R.J.1    Pagano, T.C.2    Hung, D.3    Raffa, R.B.4
  • 42
    • 31744435871 scopus 로고    scopus 로고
    • Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies
    • Skol AD, Scott LJ, Abecasis GR, Boehnke M. 2006. Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nat Genet 38(2):209-213.
    • (2006) Nat Genet , vol.38 , Issue.2 , pp. 209-213
    • Skol, A.D.1    Scott, L.J.2    Abecasis, G.R.3    Boehnke, M.4
  • 43
    • 1842734649 scopus 로고    scopus 로고
    • Modulation of memory by insulin and glucose: Neuropsychological observations in Alzheimer's disease
    • Watson GS, Craft S. 2004. Modulation of memory by insulin and glucose: Neuropsychological observations in Alzheimer's disease. Eur J Pharmacol 490(1-3):97-113.
    • (2004) Eur J Pharmacol , vol.490 , Issue.1-3 , pp. 97-113
    • Watson, G.S.1    Craft, S.2
  • 45
    • 24044550689 scopus 로고    scopus 로고
    • PEDSTATS: Descriptive statistics, graphics and quality assessment for gene mapping data
    • Wigginton JE, Abecasis GR. 2005. PEDSTATS: Descriptive statistics, graphics and quality assessment for gene mapping data. Bioinformatics 21(16):3445-3447.
    • (2005) Bioinformatics , vol.21 , Issue.16 , pp. 3445-3447
    • Wigginton, J.E.1    Abecasis, G.R.2
  • 46
    • 2142810270 scopus 로고    scopus 로고
    • Lipid metabolism in women
    • Williams CM. 2004. Lipid metabolism in women. Proc Nutr Soc 63:153-160.
    • (2004) Proc Nutr Soc , vol.63 , pp. 153-160
    • Williams, C.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.