Attenuation of ozone-induced airway inflammation and hyper-responsiveness by c-Jun NH2 terminal kinase inhibitor SP600125

Journal of Pharmacology and Experimental Therapeutics

Volumn 322, Issue 1, 2007, Pages 351-359

  Williams, Alison S ^a   Issa, Razao ^a   Sum, Yee Leung ^a   Nath, Puneeta ^a   Ferguson, Gregory D ^b   Bennett, Brydon L ^b   Adcock, Ian M ^a   Kian, Fan Chung ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b Celgene   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN 1; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CXCL1 CHEMOKINE; FACTOR 1 ALPHA; FIBRINOGEN; HEMOPEXIN; INTERLEUKIN 6; MESSENGER RNA; METALLOTHIONEIN I; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; OZONE; PHOSPHOTRANSFERASE INHIBITOR; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AIRWAY HYPERRESPONSIVENESS; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENETIC ANALYSIS; HYPOXIA; LUNG; LUNG LAVAGE; MALE; MICROARRAY ANALYSIS; MODULATION; MOLECULE; MOUSE; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY TRACT DISEASE;

ANIMALS; ANTHRACENES; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; GENE EXPRESSION REGULATION; INFLAMMATION; INTERLEUKIN-6; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LUNG; MALE; MICE; MICE, INBRED BALB C; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OZONE; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-JUN;

EID: 34250709565     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.107.121624     Document Type: Article

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