Airway inflammatory response to ozone in subjects with different asthma severity

European Respiratory Journal

Volumn 13, Issue 2, 1999, Pages 274-280

  Vagaggini, B ^a   Carnevali, S ^b   Macchioni, P ^b   Taccola, M ^b   Fornai, E ^b   Bacci, E ^b   Bartoli, M L ^b   Cianchetti, S ^b   Dente, F L ^b   Di Franco, A ^b   Giannini, D ^b   Paggiaro, P L ^b  

^a CISANELLO HOSPITAL   (Italy)

^b NONE

Author keywords

Asthma severity; Ozone; Sputum induction; Sputum interleukin 8; Sputum neutrophils

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CORTICOSTEROID; EOSINOPHIL CATIONIC PROTEIN; INTERLEUKIN 8; OZONE;

ADOLESCENT; ADULT; ARTICLE; ASTHMA; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; HUMAN CELL; LUNG FUNCTION TEST; MALE; NEUTROPHIL; PRIORITY JOURNAL; RESPIRATORY TRACT INFLAMMATION; SPUTUM ANALYSIS; SPUTUM CYTODIAGNOSIS; SYMPTOMATOLOGY;

ADOLESCENT; ADULT; ASTHMA; BLOOD PROTEINS; CROSS-OVER STUDIES; EOSINOPHIL GRANULE PROTEINS; EOSINOPHILS; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; INTERLEUKIN-8; LEUKOCYTE COUNT; MALE; NEUTROPHILS; OXIDANTS, PHOTOCHEMICAL; OZONE; PEAK EXPIRATORY FLOW RATE; RIBONUCLEASES; SINGLE-BLIND METHOD; SPUTUM;

EID: 0032979070     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3003.1999.13b09.x     Document Type: Article

References (35)

1. Romieu I, Meneses F, Ruiz S, et al. Effects of air pollution on the respiratory health of asthmatic children living in Mexico City. Am J Respir Crit Care Med 1996; 154: 300-307.
2. Schwartz J. Air pollution and hospital admissions for the eldery in Detroit, Michigan. Am J Respir Crit Care Med 1994; 150: 648-655.
3. Holtzman MJ, Cunningham JH, Sheller JR, Irsigler GB, Nadel JA, Boushey HA. Effect of ozone on bronchial reactivity in atopic and nonatopic subjects. Am Rev Respir Dis 1979; 120: 1059-1067.
4. Kreit JW, Gross KB, Moore TB, Lorenzen TJ, D'Arcy J, Eschenbacher WL. Ozone-induced changes in pulmonary function and bronchial responsiveness in asthmatics. J Appl Physiol 1989; 66(1): 217-222.
5. Molfino NA, Wright SC, Katz I. et al. Effect of low concentrations of ozone on inhaled allergen responses in asthmatic subjects. Lancet 1991; 338: 199-203.
6. Jorres R, Nowak D, Magnussen H. The effect of ozone exposure on allergen responsiveness in subjects with asthma or rhinits. Am J Respir Crit Care Med 1996; 153: 56-64.
7. Koren HS, Devlin RB, Graham DE, et al. Ozone-induced inflammation in the lower airways of human subjects. Am Res Respir Dis 1989; 139: 407-415.
8. Linn WS, Shamoo DA, Anderson KR, Peng RC, Avol EL, Hackney JD. Effects of prolonged, repeated exposure to ozone, sulfuric acid, and their combination in healthy and asthmatic volunteers. Am J Respir Crit Care Med 1994; 150: 431-440.
9. Basha MA, Gross KB, Gwizdala CJ, Haidar AH, Popovich J. Bronchoalveolar lavage neutrophilia in asthmatic and healthy volunteers after controlled exposure to ozone and filtered purified air. Chest 1994; 106: 1757-1765.
10. Scannell C, Chen L, Aris RM, et al. Greater ozone-induced inflammatory responses in subjects with asthma. Am J Respir Crit Care Med 1996; 154: 24-29.
11. Hiltermann TJ, Stolk J, Hiemstra PS, et al. Effect of ozone exposure on maximal airway narrowing in non asthmatic and asthmatic subjects. Clin Sci 1995; 89: 619-624.
12. National Institutes of Health. Global Initiative for Asthma. NIH publication 1995; No. 95: 3659 January.
13. Pizzichini E, Pizzichini MMM, Efthimiadis A, et al. Indices of airway inflammation in induced sputum: reproducibility and validity of cell and fluid-phase measurements, Am J Respir Crit Care Med 1996; 154: 308-317.
14. Hargreave FE, Popov J, Kidney J, Dolovich J. Sputum measurements to assess airway inflammation in asthma. Allergy 1993; 48: 81-83.
15. Paggiaro PL, Vagaggini B, Dente FL, et al. Bronchial hyperresponsiveness and toluene diisocyanate: long-term change in sensitized asthmatic subjects. Chest 1993; 103: 1123-1128.
16. Bacci E, Cianchetti S, Paggiaro PL, et al. Comparison between hypertonic and isotonic saline-induced sputum in the evaluation of airway inflammation in subjects with moderate asthma. Clin Exp Allergy 1996; 26: 1395-1400.
17. Bacci E, Cianchetti S, Bartoli ML, et al. Reproducibility of induced sputum cell analysis in the evaluation of airway inflammation in asthma. Eur Respir J 1996; 9: Suppl. 23, 119s (abstract).
18. Schegle ES, Siefkin AD, McDonald RJ. Time-course of ozone-induced neutrophilia in normal humans. Am Rev Respir Dis 1991; 143: 1353-1358.
19. Aris RM, Christian D, Hearne PQ, Kerr K, Finkbeiner KWE, Balmes JR. Ozone induced airway inflammation in human subjects as determined by airway lavage and biopsy. Am Rev Respir Dis 1993; 148: 1363-1372.
20. 2 exposure on induced sputum in normal, asthmatic and COPD subjects. Eur Respir J 1996; 9: 1852-1857.
21. Fahy JV, Wong HH, Llu JT, Boushey HA. Analysis of induced sputum after air and ozone exposures in healthy subjects. Environ Res 1996; 70: 70-72.
22. Linn WS, Anderson KR, Shamoo DA, et al. Controlled exposures of young asthmatics to mixed oxidant gases and acid aerosol. Am J Respir Crit Care Med 1995; 152: 885-891.
23. Stevens WHM, Adelroth E, Woolley MJ, Wattie J, Dahlback M, O'Byrne PM. The effects of an inhaled corticosteroid on oxygen radical production by bronchoalveolar cells after allergen or ozone in dogs. Eur J Pharmacol Environ Toxicol Pharmacol Sec 1995; 293: 251-257.
24. Brattsand R, Pipkorn U. Glucocorticoids. Experimental approaches. In: Kaliner MA, Barnes PJ, Persson CGA, eds. Asthma. Its Pathology and Treatment. New York, Marcel Dekker Inc., 1991; pp. 667-709.
25. Chitano P, Hosselet JJ, Mapp CE, Fabbri LM. Effect of oxidant air pollutants on the respiratory system: insights from experimental animal research. Eur Respir J 1995; 8: 1357-1371.
26. Bottei GM, Devlin RB, Bromberg PA, Peden DB. The effect of corticosteroids on lower airways inflammation and pulmonary function after ozone exposure (abstract). Am J Respir Crit Care Med 1995; 151 (4, part 2): A28.
27. Gong H Jr, Bedi JF, Horvath SM. Inhaled albuterol does not protect against ozone toxicity in nonasthmatic athletes. Arch environ Health 1988; 43: 46-53.
28. Ying RL, Gross KB, Terzo TS, Eschenbacher WL. Indomethacin does not inhibit the ozone induced increase in bronchial responsiveness in human subjects. Am Rev Respir Dis 1990; 142: 817-821.
29. Mudway I, Kelly FJ, Krishma T, et al. Upper airways loss of uric acid during exposures to ozone. Eur Respir J 1996; 9: Suppl. 23; 415s (abstract).
30. Lund K, Dunster C, Refsnes M, et al. Antioxidant response in lung lining fluid of subjects exposed to hydrogen fluoride. Eur Respir J 1996; 9: Suppl. 23; 416s (abstract).
31. Barnes PJ. Poorly perceived asthma. Thorax 1992; 47: 408-409.
32. Leikauf GD, Driscoll KE, Wey HE. Ozone-induced augmentation of eicosanoid metabolism in epithelial cells from bovine trachea. Am Rev Respir Dis 1988; 137: 435-442.
33. Commitee of Environmental and Occupational Health Assembly of ATS. Health effects of outdoor air pollution. State of the Art. Am J Respir Crit Care Med 1996; 153: 3-50.
34. McDonnel WF, Muller KE, Bromberg PA, Shy CM. Predictors of individual differences in acute response to ozone exposure. Am Rev Respir Dis 1993; 147: 818-825.
35. Wong HH, Fahy JV. Safety of one method of sputum induction in asthmatic subjects. Am J Respir Crit Care Med 1997; 156: 299-303.