Molecular surface features in modeling the HIV-1 RT inhibitory activity of 2-(2,6-disubstituted phenyl)-3-(substituted pyrimidin-2-yl)-thiazolidin-4-ones

QSAR and Combinatorial Science

Volumn 26, Issue 3, 2007, Pages 398-406

  Rawal, Ravindra K ^a   Prabhakar, Yenamandra S ^a   Katti, Setu B ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Electronic descriptors; HIV 1 RT; Molecular surface area features; Non nucleoside reverse transcriptase inhibitors; QSAR

Indexed keywords

COMPUTATIONAL CHEMISTRY; DISEASES; VIRUSES;

AREA FEATURE; DESCRIPTORS; ELECTRONIC DESCRIPTOR; HUMAN IMMUNODEFICIENCY VIRUS-1; HUMAN IMMUNODEFICIENCY VIRUS-1 REVERSE TRANSCRIPTASE; MOLECULAR SURFACE AREA; MOLECULAR SURFACE AREA FEATURE; NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS; QSAR; REVERSE-TRANSCRIPTASE;

MULTIPLE LINEAR REGRESSION;

2 (2,6 PHENYL) 3 (PYRIMIDIN 2 YL) THIAZOLIDIN 4 ONES; PYRIMIDINE DERIVATIVE; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; COMPUTER PROGRAM; DRUG ACTIVITY; DRUG INHIBITION; HYDROPHOBICITY; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 34250676593     PISSN: 1611020X     EISSN: 16110218     Source Type: Journal    
DOI: 10.1002/qsar.200630040     Document Type: Article

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