CP-MLR/PLS directed structure-activity modeling of the HIV-1 RT inhibitory activity of 2,3-diaryl-1,3-thiazolidin-4-ones

QSAR and Combinatorial Science

Volumn 23, Issue 4, 2004, Pages 234-244

  Prabhakar, Yenamandra S ^a   Solomon, V Raja ^a   Rawal, Ravindra K ^a   Gupta, Manish K ^a   Katti, S B ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Combinatorial protocol in multiple regression; HIV 1 RT inhibitory activity; Partial least squares; QSAR; Thiazolidinones

Indexed keywords

COMPUTATIONAL CHEMISTRY; HYDROPHOBICITY; LEAST SQUARES APPROXIMATIONS; MULTIPLE LINEAR REGRESSION; NITROGEN;

COMBINATORIAL PROTOCOL IN MULTIPLE REGRESSION; DESCRIPTORS; HIV-1 REVERSE TRANSCRIPTASE; HIV-1 REVERSE TRANSCRIPTASE INHIBITORY ACTIVITY; INHIBITORY ACTIVITY; MULTIPLE REGRESSIONS; PARTIAL LEAST-SQUARES; QSAR; THIAZOLIDIN-4-ONES; THIAZOLIDINONE;

CONFORMATIONS;

1,3 THIAZINE DERIVATIVE; 1,3 THIAZOLIDIN 4 ONE DERIVATIVE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; NITROGEN; PHENYL GROUP; PYRIDINE DERIVATIVE; RNA DIRECTED DNA POLYMERASE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; COMBINATORIAL CHEMISTRY; COMBINATORIAL PROTOCOL INTERFACED MULTIPLE LINEAR REGRESSION; DRUG ACTIVITY; DRUG CONFORMATION; DRUG INHIBITION; DRUG STRUCTURE; ENZYME INHIBITION; GEOMETRY; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROPHOBICITY; PARTIAL LEAST SQUARE ANALYSIS; PHYSICAL CHEMISTRY; POLARIZATION; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REGRESSION ANALYSIS; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 8544239371     PISSN: 1611020X     EISSN: None     Source Type: Journal    
DOI: 10.1002/qsar.200330854     Document Type: Article

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