Synthesis of new 2,3-diaryl-1,3-thiazolidin-4-ones as anti-HIV agents

Farmaco

Volumn 59, Issue 1, 2004, Pages 33-39

  Rao, Angela ^a   Balzarini, Jan ^b   Carbone, Anna ^a   Chimirri, Alba ^a   De Clercq, Erik ^b   Monforte, Anna Maria ^a   Monforte, Pietro ^a   Pannecouque, Christophe ^b   Zappalà, Maria ^a  

^a UNIVERSITY OF MESSINA   (Italy)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

2,3 diaryl 1,3 thiazolidin 4 ones; Anti HIV activity; NNRTIs

Indexed keywords

2 (2 CHLORO 6 FLUORO 3 METHYLPHENYL) 3 (3 METHYLPHENYL) 1,3 THIAZOLIDIN 4 ONE; 2 (2 CHLORO 6 FLUORO 3 METHYLPHENYL) 3 (4 METHYLPYRIDIN 2 YL) 1,3 THIAZOLIDIN 4 ONE; 2 (2 CHLORO 6 FLUORO 3 METHYLPHENYL) 3 (4,6 DIMETHYLPYRIDIN 2 YL) 1,3 THIAZOLIDIN 4 ONE; 2 (2 CHLORO 6 FLUORO 3 METHYLPHENYL) 3 (6 METHYLPYRIDIN 2 YL) 1,3 THIAZOLIDIN 4 ONE; 2 (2 FLUORO 6 METHOXYPHENYL) 3 (4 METHYLPYRIDIN 2 YL) 1,3 THIAZOLIDIN 4 ONE; 2 (2 FLUORO 6 METHOXYPHENYL) 3 (6 METHYLPYRIDIN 2 YL) 1,3 THIAZOLIDIN 4 ONE; 2 (2,6 DIMETHOXYPHENYL) 3 (3 METHYLPHENYL) 1,3 THIAZOLIDIN 4 ONE; 2 (2,6 DIMETHOXYPHENYL) 3 (4 METHYLPYRIDIN 2 YL) 1,3 THIAZOLIDIN 4 ONE; 2 (2,6 DIMETHOXYPHENYL) 3 (4,6 DIMETHYLPYRIDIN 2 YL) 1,3 THIAZOLIDIN 4 ONE; 2 (2,6 DIMETHOXYPHENYL) 3 (6 METHYLPYRIDIN 2 YL) 1,3 THIAZOLIDIN 4 ONE; 2 (2,6 DIMETHYLPHENYL) 3 (3 METHYLPHENYL) 1,3 THIAZOLIDIN 4 ONE; 2 (2,6 DIMETHYLPHENYL) 3 (4 METHYLPYRIDIN 2 YL) 1,3 THIAZOLIDIN 4 ONE; 2 (2,6 DIMETHYLPHENYL) 3 (4 METHYLPYRIMIDIN 2 YL) 1,3 THIAZOLIDIN 4 ONE; 2 (2,6 DIMETHYLPHENYL) 3 (4,6 DIMETHYLPYRIDIN 2 YL) 1,3 THIAZOLIDIN 4 ONE; 2 (2,6 DIMETHYLPHENYL) 3 (6 METHYLPYRIDIN 2 YL) 1,3 THIAZOLIDIN 4 ONE; 2 (3 CHLORO 2 FLUORO 6 TRIFLUOROMETHYLPHENYL) 3 (3 METHYLPHENYL) 1,3 THIAZOLIDIN 4 ONE; 2 (3 CHLORO 2 FLUORO 6 TRIFLUOROMETHYLPHENYL) 3 (4 METHYLPYRIDIN 2 YL) 1,3 THIAZOLIDIN 4 ONE; 2 (3 CHLORO 2 FLUORO 6 TRIFLUOROMETHYLPHENYL) 3 (4,6 DIMETHYLPYRIDIN 2 YL) 1,3 THIAZOLIDIN 4 ONE; 2 (3 CHLORO 2 FLUORO 6 TRIFLUOROMETHYLPHENYL) 3 (6 METHYLPYRIDIN 2 YL) 1,3 THIAZOLIDIN 4 ONE; 2 (FLUORO 6 METHOXYPHENYL) 3 (3 METHYLPHENYL) 1,3 THIAZOLIDIN 4 ONE; 3 (4,6 DIMETHYLPYRIDIN 2 YL) 2 (2 FLUORO 6 METHOXYPHENYL) 1,3 THIAZOLIDIN 4 ONE; 3 (6 BROMOPYRIDIN 2 YL) 2 (2 CHLORO 6 FLUORO 3 METHYLPHENYL) 1,3 THIAZOLIDIN 4 ONE; 3 (6 BROMOPYRIDIN 2 YL) 2 (2 FLUORO 6 METHOXYPHENYL) 1,3 THIAZOLIDIN 4 ONE; 3 (6 BROMOPYRIDIN 2 YL) 2 (2,6 DIMETHOXYPHENYL) 1,3 THIAZOLIDIN 4 ONE; 3 (6 BROMOPYRIDIN 2 YL) 2 (2,6 DIMETHYLPHENYL) 1,3 THIAZOLIDIN 4 ONE; 3 (6 BROMOPYRIDIN 2 YL) 2 (3 CHLORO 2 FLUORO 6 TRIFLUOROMETHYLPHENYL) 1,3 THIAZOLIDIN 4 ONE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; RNA DIRECTED DNA POLYMERASE INHIBITOR; THIAZOLIDINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; VIRUS INHIBITION; VIRUS REPLICATION;

EID: 1642538940     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.farmac.2003.09.001     Document Type: Article

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