Mimicking enzymes: Cooperation between organic functional groups and metal ions in the cleavage of phosphate diesters

Chemistry - A European Journal

Volumn 13, Issue 8, 2007, Pages 2246-2256

  Livieri, Monica ^a   Mancin, Fabrizio ^a   Saielli, Giacomo ^b   Chin, Jik ^c   Tonellato, Umberto ^a,b  

^a UNIVERSITY OF PADOVA   (Italy)

^b INSTITUTE ON MEMBRANE TECHNOLOGY   (Italy)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Artificial nucleases; Catalysis; Hydrogen bonds; Hydrolysis; Phosphate diesters

Indexed keywords

CATALYSIS; ESTERS; FUNCTIONAL GROUPS; HYDROGEN BONDS; HYDROLYSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOPHILES;

ARTIFICIAL NUCLEASES; HYDROLYTIC ACTIVITY; PHOSPHATE DIESTERS;

ENZYME KINETICS;

2 (HYDROXYPROPYL) 4 NITROPHENYL PHOSPHATE; 2-(HYDROXYPROPYL)-4-NITROPHENYL PHOSPHATE; BIS(4 NITROPHENYL) PHOSPHATE; BIS(4-NITROPHENYL)PHOSPHATE; ESTER; METHYLAMINE; NITROPHENOL; ORGANOPHOSPHORUS COMPOUND; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG; ZINC;

ARTICLE; CATALYSIS; CHEMISTRY; KINETICS;

CATALYSIS; ESTERS; KINETICS; METHYLAMINES; NITROPHENOLS; ORGANOPHOSPHORUS COMPOUNDS; PYRIDINES; ZINC;

EID: 34250630803     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.200600672     Document Type: Article

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