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Volumn 120, Issue 27, 1998, Pages 6726-6737

Efficient catalytic phosphate diester cleavage by the synergetic action of two Cu(II) centers in a dinuclear cis-diaqua Cu(II) calix[4larene enzyme model

Author keywords

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Indexed keywords

METALLOPROTEIN;

EID: 0032527953     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9805324     Document Type: Article
Times cited : (182)

References (111)
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    • For a discussion about rate enhancements see ref 12.
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    • obs obtained by extrapolation of the observed first-order dependency at 0-0.2 mM 3-Cu(II) to 0.48 mM 3-Cu(II).
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    • s = ±2 half-field transition caused by the triplet state of dimeric Cu(II) complexes. This half-field transition is theoretically forbidden and thus often of low intensity, whereas it is sometimes not observed at all. Lack of this EPR signal is therefore not a guarantee for the absence of dimeric Cu(II) species. For further information about EPR spectroscopy with Cu(II) complexes, see refs 13h, 15, and the following: (a) Chaudhuri, P.; Oder, K. J. Chem. Soc., Dalton Trans. 1990, 1597. (b) Siddiqui, S.; Shepherd, R. E. Inorg. Chem. 1986, 25, 3869. (c) Chaudhuri, P.; Ventur, D.; Wieghardt, K.; Peters, E. M.; Peters, K.; Simon, A. Angew. Chem., Int. Ed. Engl. 1985, 24, 57. (d) Barnes, J. A.; Hodgson, D. J.; Hatfield. W. E. Inorg. Chem. 1972, 11, 144. (e) Walker, A.; Sigel, H.; McCormick, D. B. Inorg. Chem. 1972, 11, 2756.
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    • s = ±2 half-field transition caused by the triplet state of dimeric Cu(II) complexes. This half-field transition is theoretically forbidden and thus often of low intensity, whereas it is sometimes not observed at all. Lack of this EPR signal is therefore not a guarantee for the absence of dimeric Cu(II) species. For further information about EPR spectroscopy with Cu(II) complexes, see refs 13h, 15, and the following: (a) Chaudhuri, P.; Oder, K. J. Chem. Soc., Dalton Trans. 1990, 1597. (b) Siddiqui, S.; Shepherd, R. E. Inorg. Chem. 1986, 25, 3869. (c) Chaudhuri, P.; Ventur, D.; Wieghardt, K.; Peters, E. M.; Peters, K.; Simon, A. Angew. Chem., Int. Ed. Engl. 1985, 24, 57. (d) Barnes, J. A.; Hodgson, D. J.; Hatfield. W. E. Inorg. Chem. 1972, 11, 144. (e) Walker, A.; Sigel, H.; McCormick, D. B. Inorg. Chem. 1972, 11, 2756.
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    • note
    • 2einf keep their catalytic activity in the transesterification of the RNA model substrate HPNP in aqueous Brij35 solution.
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    • note
    • This was also concluded for one of the dinuclear Cu(II) complexes of Chin, see ref 6.


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