An allosteric synthetic catalyst: Metal ions tune the activity of an artificial phosphodiesterase

Chemistry - A European Journal

Volumn 7, Issue 6, 2001, Pages 1221-1231

  Fritsky, Igor O ^a,b   Ott, Reina ^a   Pritzkow, Hans ^a   Krämer, Roland ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV   (Ukraine)

Author keywords

Allosterism; Catalysts; Copper; Enzyme models; Phosphodiester cleavage

Indexed keywords

CATALYSTS; COPPER; ESTERS; PHOTOMETRY; RNA;

CLEAVAGE RATE;

CATALYST ACTIVITY;

2 (HYDROXYPROPYL) 4 NITROPHENYLPHOSPHATE; COPPER; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; METAL COMPLEX; METAL ION; NICKEL; NITROPHENOL; ORGANOPHOSPHORUS COMPOUND; PHOSPHODIESTERASE; PHOSPHORUS DERIVATIVE; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; BINDING SITE; CATALYSIS; CATALYST; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; CONFORMATION; CRYSTAL STRUCTURE; KINETICS; METAL BINDING; MOLECULAR MIMICRY; NITROPHENYL PHOSPHATE; STRUCTURE ACTIVITY RELATION; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

ALLOSTERIC REGULATION; CATALYSIS; COPPER; CRYSTALLOGRAPHY, X-RAY; INDICATORS AND REAGENTS; KINETICS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR MIMICRY; NICKEL; NITROPHENOLS; ORGANOPHOSPHORUS COMPOUNDS; PHOSPHORIC DIESTER HYDROLASES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035896243     PISSN: 09476539     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-3765(20010316)7:6<1221::AID-CHEM1221>3.0.CO;2-T     Document Type: Article

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