메뉴 건너뛰기




Volumn 82, Issue 5, 1997, Pages 1458-1461

The use of tolbutamide-induced hypoglycemia to examine the intraislet role of insulin in mediating glucagon release in normal humans

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; C PEPTIDE; GLUCAGON; INSULIN; TOLBUTAMIDE;

EID: 0030971354     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.82.5.1458     Document Type: Article
Times cited : (43)

References (32)
  • 1
    • 0017127682 scopus 로고
    • The role of adrenergic mechanisms in the substrate and hormonal response to insulin induced hypoglycemia in man
    • Garber AJ, Cryer PE, Santiago JV, Haymond MW, Pagliara AS, Kipnis DM. 1976 The role of adrenergic mechanisms in the substrate and hormonal response to insulin induced hypoglycemia in man. J Clin Invest. 58:7-15.
    • (1976) J Clin Invest , vol.58 , pp. 7-15
    • Garber, A.J.1    Cryer, P.E.2    Santiago, J.V.3    Haymond, M.W.4    Pagliara, A.S.5    Kipnis, D.M.6
  • 2
    • 0018462727 scopus 로고
    • Hormonal mechanisms of recovery from insulin induced hypoglycemia in man
    • Gerich JE, Davis J, Lorenzi M, et al. 1979 Hormonal mechanisms of recovery from insulin induced hypoglycemia in man. Am J Physiol. 236:E380-E385.
    • (1979) Am J Physiol , vol.236
    • Gerich, J.E.1    Davis, J.2    Lorenzi, M.3
  • 3
    • 0018757294 scopus 로고
    • Role of glucagon, catecholamines and growth hormone in human glucose counterregulation
    • Rizza RA, Cryer PE, Gerich JE. 1979 Role of glucagon, catecholamines and growth hormone in human glucose counterregulation. J Clin Invest. 64:62-71.
    • (1979) J Clin Invest , vol.64 , pp. 62-71
    • Rizza, R.A.1    Cryer, P.E.2    Gerich, J.E.3
  • 4
    • 0020505255 scopus 로고
    • Insulin-glucagon relationships in the defense against hypoglycemia
    • Unger RH. 1983 Insulin-glucagon relationships in the defense against hypoglycemia. Diabetes. 32:575-583.
    • (1983) Diabetes , vol.32 , pp. 575-583
    • Unger, R.H.1
  • 5
    • 0015901935 scopus 로고
    • Lack of glucagon response to hypoglycemia in diabetes: Evidence for an intrinsic pancreatic alpha cell defect
    • Gerich JE, Langlois M, Noacco C, Karam JH, Forsham PH. 1973 Lack of glucagon response to hypoglycemia in diabetes: evidence for an intrinsic pancreatic alpha cell defect. Science. 182:171-173.
    • (1973) Science , vol.182 , pp. 171-173
    • Gerich, J.E.1    Langlois, M.2    Noacco, C.3    Karam, J.H.4    Forsham, P.H.5
  • 6
    • 0020700793 scopus 로고
    • Abnormal glucose counterregulation in IDDM. Interaction of anti-insulin antibodies and impaired glucagon and epinephrine secretion
    • Bolli GB, De Feo P, Compagnucci P, et al. 1983 Abnormal glucose counterregulation in IDDM. Interaction of anti-insulin antibodies and impaired glucagon and epinephrine secretion. Diabetes. 32:134-141.
    • (1983) Diabetes , vol.32 , pp. 134-141
    • Bolli, G.B.1    De Feo, P.2    Compagnucci, P.3
  • 7
    • 0019792406 scopus 로고
    • Severe insulin-induced hypoglycemia associated with deficiencies in the release of counterregulatory hormones
    • Boden G, Reichard GAJ, Hoeldtke RD, Rezvani I, Owen OE. 1981 Severe insulin-induced hypoglycemia associated with deficiencies in the release of counterregulatory hormones. N Engl J Med. 305:1200-1205.
    • (1981) N Engl J Med , vol.305 , pp. 1200-1205
    • Boden, G.1    Reichard, G.A.J.2    Hoeldtke, R.D.3    Rezvani, I.4    Owen, O.E.5
  • 8
    • 0024397747 scopus 로고
    • Responses of the pancreatic A cell during hypoglycemia and hyperglycemia are dependant on the B cell
    • McCulloch DK, Raghu PK, Koerker DJ, Palmer JP, Klaff LJ. 1989 Responses of the pancreatic A cell during hypoglycemia and hyperglycemia are dependant on the B cell. Metabolism. 38:702-707.
    • (1989) Metabolism , vol.38 , pp. 702-707
    • McCulloch, D.K.1    Raghu, P.K.2    Koerker, D.J.3    Palmer, J.P.4    Klaff, L.J.5
  • 9
    • 0025884065 scopus 로고
    • A high concentration of circulating insulin suppresses the glucagon response to hypoglycemia in normal man
    • Liu D, Moberg E, Kollind M, Lins PE, Adamson U. 1991 A high concentration of circulating insulin suppresses the glucagon response to hypoglycemia in normal man. J Clin Endocrinol Metab. 73:1123-1128.
    • (1991) J Clin Endocrinol Metab , vol.73 , pp. 1123-1128
    • Liu, D.1    Moberg, E.2    Kollind, M.3    Lins, P.E.4    Adamson, U.5
  • 10
    • 0025835918 scopus 로고
    • Suppression of counterregulatory hormone response to hypoglycemia by insulin per se
    • Diamond MP, Hallerman L, Starick-Zych K, et al. 1991 Suppression of counterregulatory hormone response to hypoglycemia by insulin per se. J Clin Endocrinol Metab. 72:1388-1390.
    • (1991) J Clin Endocrinol Metab , vol.72 , pp. 1388-1390
    • Diamond, M.P.1    Hallerman, L.2    Starick-Zych, K.3
  • 11
    • 0021258630 scopus 로고
    • Mechanisms of glucagon secretion during insulin-induced hypoglycemia in man:role of the beta cell and arterial hyperinsulinemia
    • Bolli GB, De Feo P, Perriello G, et al. 1984 Mechanisms of glucagon secretion during insulin-induced hypoglycemia in man:role of the beta cell and arterial hyperinsulinemia. J Clin Invest. 73:917-922.
    • (1984) J Clin Invest , vol.73 , pp. 917-922
    • Bolli, G.B.1    De Feo, P.2    Perriello, G.3
  • 12
    • 0027409194 scopus 로고
    • The effects of differing insulin levels on the hormonal and metabolic response to equivalent hypoglycemia in normal humans
    • Davis SN, Goldstein RE, Jacobs J, Price L, Wolfe R, Cherrington AD. 1993 The effects of differing insulin levels on the hormonal and metabolic response to equivalent hypoglycemia in normal humans. Diabetes. 42:263-272.
    • (1993) Diabetes , vol.42 , pp. 263-272
    • Davis, S.N.1    Goldstein, R.E.2    Jacobs, J.3    Price, L.4    Wolfe, R.5    Cherrington, A.D.6
  • 13
    • 0026597462 scopus 로고
    • Arterial, arterialised venous, venous and capillary blood glucose measurements in normal man during hyperinsulinaemic euglycaemia and hypoglycaemia
    • Liu D, Moberg E, Kollind M, Lins P-E, Adamson U. 1992 Arterial, arterialised venous, venous and capillary blood glucose measurements in normal man during hyperinsulinaemic euglycaemia and hypoglycaemia. Diabetologia. 35:287-290.
    • (1992) Diabetologia , vol.35 , pp. 287-290
    • Liu, D.1    Moberg, E.2    Kollind, M.3    Lins, P.-E.4    Adamson, U.5
  • 14
    • 0016815257 scopus 로고
    • Dynamics of tolbutamide, glucose and insulin interrelationships following varying doses of intravenous tolbutamide in normal subjects
    • Ganda OP, Khan CB, Soeldner JS, Gleason RE. 1975 Dynamics of tolbutamide, glucose and insulin interrelationships following varying doses of intravenous tolbutamide in normal subjects. Diabetes. 24:354-361.
    • (1975) Diabetes , vol.24 , pp. 354-361
    • Ganda, O.P.1    Khan, C.B.2    Soeldner, J.S.3    Gleason, R.E.4
  • 15
    • 0001731585 scopus 로고
    • The assay of the catecholamine content of small volumes of human plasma
    • Rollema H, Westerink BHC, Drijfhout WJ, eds. Groningen: University Centre for Pharmacy
    • Forster CD, Taylor JY, Macdonald IA. 1991 The assay of the catecholamine content of small volumes of human plasma. In: Rollema H, Westerink BHC, Drijfhout WJ, eds. Monitoring molecules in neuroscience. Groningen: University Centre for Pharmacy; 173-175.
    • (1991) Monitoring Molecules in Neuroscience , pp. 173-175
    • Forster, C.D.1    Taylor, J.Y.2    Macdonald, I.A.3
  • 16
    • 0017264213 scopus 로고
    • Triglyceride metabolism in acute starvation: The role of secretin and glucagon
    • Stout RW, Henry RW, Buchanan KD. 1976 Triglyceride metabolism in acute starvation: the role of secretin and glucagon. Eur J Clin Invest. 6:179-185.
    • (1976) Eur J Clin Invest , vol.6 , pp. 179-185
    • Stout, R.W.1    Henry, R.W.2    Buchanan, K.D.3
  • 17
    • 0016830667 scopus 로고
    • Radioimmunological determinations of human C-peptide in serum
    • Heding LG. 1975 Radioimmunological determinations of human C-peptide in serum. Diabetologia. 11:541-554.
    • (1975) Diabetologia , vol.11 , pp. 541-554
    • Heding, L.G.1
  • 18
    • 0013828842 scopus 로고
    • Critical variables in the RIA of serum insulin using the double antibody system
    • Soeldner JS, Sloane D. 1965 Critical variables in the RIA of serum insulin using the double antibody system. Diabetes. 14:771-779.
    • (1965) Diabetes , vol.14 , pp. 771-779
    • Soeldner, J.S.1    Sloane, D.2
  • 19
    • 0018956367 scopus 로고
    • Prehepatic insulin production in man: Kinetic analysis using peripheral connecting peptide behaviour
    • Eaton RP, Allen RC, Schade DS, Erickson KM, Standefer J. 1980 Prehepatic insulin production in man: kinetic analysis using peripheral connecting peptide behaviour. J Clin Endocrinol Metab. 51:520-528.
    • (1980) J Clin Endocrinol Metab , vol.51 , pp. 520-528
    • Eaton, R.P.1    Allen, R.C.2    Schade, D.S.3    Erickson, K.M.4    Standefer, J.5
  • 20
    • 0022572232 scopus 로고
    • Use of biosynthetic human c-peptide in the measurement of insulin secretion rates in normal volunteers and type 1 diabetic patients
    • Polonsky KS, Licinio-Paixao J, Given BD, et al. 1986 Use of biosynthetic human c-peptide in the measurement of insulin secretion rates in normal volunteers and type 1 diabetic patients. J Clin Invest. 77:98-105.
    • (1986) J Clin Invest , vol.77 , pp. 98-105
    • Polonsky, K.S.1    Licinio-Paixao, J.2    Given, B.D.3
  • 21
    • 0020684724 scopus 로고
    • Regulation of the splanchnic and peripheral glucose uptake by insulin and hyperglycemia in man
    • DeFronzo RE, Ferrannini E, Hendler R, Felig P, Wahren J. 1983 Regulation of the splanchnic and peripheral glucose uptake by insulin and hyperglycemia in man. Diabetes. 32:35-45.
    • (1983) Diabetes , vol.32 , pp. 35-45
    • DeFronzo, R.E.1    Ferrannini, E.2    Hendler, R.3    Felig, P.4    Wahren, J.5
  • 22
    • 0022477284 scopus 로고
    • Comparison of glucose counterregulation during short-term and prolonged hypoglycemia in normal humans
    • De Feo P, Perriello G, DeCosmo S, et al. 1986 Comparison of glucose counterregulation during short-term and prolonged hypoglycemia in normal humans. Diabetes. 35:563-569.
    • (1986) Diabetes , vol.35 , pp. 563-569
    • De Feo, P.1    Perriello, G.2    DeCosmo, S.3
  • 23
    • 0022590438 scopus 로고
    • Simulation of the normal glucopenia-induced decline in insulin partially restores the glucagon response to glucopenia in isolated perfused pancreata of streptozotocin -diabetic rats
    • Tominaga M, Maruyama H, Bolli G, Helderman JH, Unger RH. 1986 Simulation of the normal glucopenia-induced decline in insulin partially restores the glucagon response to glucopenia in isolated perfused pancreata of streptozotocin -diabetic rats. Endocrinology. 118:886-887.
    • (1986) Endocrinology , vol.118 , pp. 886-887
    • Tominaga, M.1    Maruyama, H.2    Bolli, G.3    Helderman, J.H.4    Unger, R.H.5
  • 24
    • 84995865300 scopus 로고
    • A new method for comparing portal and peripheral venous insulin delivery in humans: Tolbutamide ve insulin infusion
    • Lewis GF, Steiner G, Polonsky KS, Weller B, Zinman B. 1994 A new method for comparing portal and peripheral venous insulin delivery in humans: Tolbutamide ve insulin infusion. J Clin Endocrinol Metab. 78:66-70.
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 66-70
    • Lewis, G.F.1    Steiner, G.2    Polonsky, K.S.3    Weller, B.4    Zinman, B.5
  • 25
    • 0030055514 scopus 로고    scopus 로고
    • Similar physiological and symptomatic responses to sulphonylurea and insulin induced hypoglycaemia in normal subjects
    • Peacey SR, George E, Rostami-Hodjegan A, et al. 1996 Similar physiological and symptomatic responses to sulphonylurea and insulin induced hypoglycaemia in normal subjects. Diabetic Med. 13:634-641.
    • (1996) Diabetic Med , vol.13 , pp. 634-641
    • Peacey, S.R.1    George, E.2    Rostami-Hodjegan, A.3
  • 26
    • 0015597356 scopus 로고
    • On the action of tolbutamide in normal man.I.role of adrenergic mechanisms in tolbutamide-induced insulin release during normoglycaemia and induced hypoglycaemia
    • Widstrom A, Cerasi E. 1973 On the action of tolbutamide in normal man.I.role of adrenergic mechanisms in tolbutamide-induced insulin release during normoglycaemia and induced hypoglycaemia. Acta Endocrinol. 72:506-518.
    • (1973) Acta Endocrinol , vol.72 , pp. 506-518
    • Widstrom, A.1    Cerasi, E.2
  • 27
    • 0019918172 scopus 로고
    • New perspectives on the microvasculature of the islets of Langerhans in the rat
    • Bonner-Weir S, Orci L. 1982 New perspectives on the microvasculature of the islets of Langerhans in the rat. Diabetes. 31:883-889.
    • (1982) Diabetes , vol.31 , pp. 883-889
    • Bonner-Weir, S.1    Orci, L.2
  • 28
    • 0023820363 scopus 로고
    • The order of islet microvascular cellular perfusion is B-A-D in the perfused rat pancreas
    • Samols E, Stagner JI, Ewart RBL, Marks V. 1988 The order of islet microvascular cellular perfusion is B-A-D in the perfused rat pancreas. J Clin Invest. 82:350-353.
    • (1988) J Clin Invest , vol.82 , pp. 350-353
    • Samols, E.1    Stagner, J.I.2    Ewart, R.B.L.3    Marks, V.4
  • 29
    • 0024520153 scopus 로고
    • Role of brain in counterregulation of insulin-induced hypoglycemia in dogs
    • Biggers DW, Myers SR, Neal D, et al. 1989 Role of brain in counterregulation of insulin-induced hypoglycemia in dogs. Diabetes. 38:7-16.
    • (1989) Diabetes , vol.38 , pp. 7-16
    • Biggers, D.W.1    Myers, S.R.2    Neal, D.3
  • 30
    • 0027327113 scopus 로고
    • Counterregulation during hypoglycemia is directed by widespread brain regions
    • Frizzell RT, Jones EM, Davis SN, et al. 1993 Counterregulation during hypoglycemia is directed by widespread brain regions. Diabetes. 42:1253-1261.
    • (1993) Diabetes , vol.42 , pp. 1253-1261
    • Frizzell, R.T.1    Jones, E.M.2    Davis, S.N.3
  • 31
    • 0019946118 scopus 로고
    • Stimulatory effects of tolbutamide infusion on plasma glucagon in insulin-dependant diabetic subjects
    • Bohannon NV, Lorenzi M, Grodsky GM, Karam JH. 1982 Stimulatory effects of tolbutamide infusion on plasma glucagon in insulin-dependant diabetic subjects. J Clin Endocrinol Metab. 54:459-462.
    • (1982) J Clin Endocrinol Metab , vol.54 , pp. 459-462
    • Bohannon, N.V.1    Lorenzi, M.2    Grodsky, G.M.3    Karam, J.H.4
  • 32
    • 0026482532 scopus 로고
    • Effect of physiological hyperinsulinemia on counterregulatory hormone responses during hypoglycemia in humans
    • Mellman MJ, Davis MR, Shamoon H. 1992 Effect of physiological hyperinsulinemia on counterregulatory hormone responses during hypoglycemia in humans. J Clin Endocrinol Metab. 75:1293-1297.
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 1293-1297
    • Mellman, M.J.1    Davis, M.R.2    Shamoon, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.