-
1
-
-
34047208826
-
Method for detection and identification of multiple chromosomal integration sites in transgenic animals created with Lentivirus
-
Bryda, E.C., Pearson, M., Agca, Y. & Bauer, B.A. Method for detection and identification of multiple chromosomal integration sites in transgenic animals created with Lentivirus. Biotechniques 41 715-719 (2006).
-
(2006)
Biotechniques
, vol.41
, pp. 715-719
-
-
Bryda, E.C.1
Pearson, M.2
Agca, Y.3
Bauer, B.A.4
-
2
-
-
33947308826
-
Generation of yeast artificial chromosome transgenic mice by intracytoplasmic sperm injection
-
Moreira, P.N., Pozueta, J., Giraldo, P., Gutierrez-Adan, A. & Montoliu, L. Generation of yeast artificial chromosome transgenic mice by intracytoplasmic sperm injection. Methods Mol. Biol. 349, 151-161 (2006).
-
(2006)
Methods Mol. Biol
, vol.349
, pp. 151-161
-
-
Moreira, P.N.1
Pozueta, J.2
Giraldo, P.3
Gutierrez-Adan, A.4
Montoliu, L.5
-
3
-
-
0018838415
-
Translation of globin messenger RNA by the mouse ovum
-
Brinster, R.L., Chen, H.Y., Trumbauer, M.E. & Avarbock, M.R. Translation of globin messenger RNA by the mouse ovum. Nature 283, 499-501 (1980).
-
(1980)
Nature
, vol.283
, pp. 499-501
-
-
Brinster, R.L.1
Chen, H.Y.2
Trumbauer, M.E.3
Avarbock, M.R.4
-
4
-
-
0019847283
-
Integration and stable germ line transmission of genes injected into mouse pronuclei
-
Gordon, J.W. & Ruddle, F.H. Integration and stable germ line transmission of genes injected into mouse pronuclei. Science 214, 1244-1246 (1981).
-
(1981)
Science
, vol.214
, pp. 1244-1246
-
-
Gordon, J.W.1
Ruddle, F.H.2
-
5
-
-
0019859395
-
Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs
-
Brinster, R.L. et al. Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs. Cell 27, 223-231 (1981).
-
(1981)
Cell
, vol.27
, pp. 223-231
-
-
Brinster, R.L.1
-
6
-
-
0019855228
-
Introduction of a rabbit beta-globin gene into the mouse germ line
-
Costantini, F. & Lacy, E. Introduction of a rabbit beta-globin gene into the mouse germ line. Nature 294, 92-94 (1981).
-
(1981)
Nature
, vol.294
, pp. 92-94
-
-
Costantini, F.1
Lacy, E.2
-
7
-
-
0019790422
-
The human beta-globin gene and a functional viral thymidine kinase gene in developing mice
-
Wagner, E.F., Stewart, T.A. & Mintz, B. The human beta-globin gene and a functional viral thymidine kinase gene in developing mice. Proc. Natl. Acad. Sci. USA 78, 5016-5020 (1981).
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 5016-5020
-
-
Wagner, E.F.1
Stewart, T.A.2
Mintz, B.3
-
8
-
-
0000051454
-
Microinjection of a rabbit beta-globin gene into zygotes and its subsequent expression in adult mice and their offspring
-
Wagner, T.E. et al. Microinjection of a rabbit beta-globin gene into zygotes and its subsequent expression in adult mice and their offspring. Proc. Natl. Acad. Sci. USA 78, 6376-6380 (1981).
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 6376-6380
-
-
Wagner, T.E.1
-
9
-
-
0032514680
-
Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Calpha
-
Gotz, J., Probst, A., Ehler, E., Hemmings, B. & Kues, W. Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Calpha. Proc. Natl. Acad. Sci. USA 95, 12370-12375 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 12370-12375
-
-
Gotz, J.1
Probst, A.2
Ehler, E.3
Hemmings, B.4
Kues, W.5
-
10
-
-
0035152814
-
Neurotrophins are required for nerve growth during development
-
Tucker, K.L., Meyer, M. & Barde, Y.A. Neurotrophins are required for nerve growth during development. Nat. Neurosci. 4, 29-37 (2001).
-
(2001)
Nat. Neurosci
, vol.4
, pp. 29-37
-
-
Tucker, K.L.1
Meyer, M.2
Barde, Y.A.3
-
11
-
-
0012315579
-
-
3rd edn, Cold Spring Harbor Press, Cold Spring Harbor, New York
-
Nagy, A., Gertsenstein, M., Vinterstein, K. & Behringer R. Manipulating the Mouse Embryo - A Laboratory Manual. 3rd edn. (Cold Spring Harbor Press, Cold Spring Harbor, New York, 2003).
-
(2003)
Manipulating the Mouse Embryo - A Laboratory Manual
-
-
Nagy, A.1
Gertsenstein, M.2
Vinterstein, K.3
Behringer, R.4
-
12
-
-
0028965635
-
Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the Longest human brain tau isoform
-
Gotz, J. et al. Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the Longest human brain tau isoform. EMBO J. 14, 1304-1313 (1995).
-
(1995)
EMBO J
, vol.14
, pp. 1304-1313
-
-
Gotz, J.1
-
13
-
-
12144287410
-
Transgenic mice expressing the nucleoprotein of Borna disease virus in either neurons or astrocytes: Decreased susceptibility to homotypic infection and disease
-
Rauer, M., Gotz, J., Schuppli, D., Staeheli, P. & Hausmann, J. Transgenic mice expressing the nucleoprotein of Borna disease virus in either neurons or astrocytes: Decreased susceptibility to homotypic infection and disease. J. Virol. 78, 3621-3632 (2004).
-
(2004)
J. Virol
, vol.78
, pp. 3621-3632
-
-
Rauer, M.1
Gotz, J.2
Schuppli, D.3
Staeheli, P.4
Hausmann, J.5
-
14
-
-
0035851175
-
Reduced PP2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice
-
Kins, S. et al. Reduced PP2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice. J. Biol. Chem. 276, 38193-38200 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 38193-38200
-
-
Kins, S.1
-
15
-
-
33646476174
-
Altered phosphorylation of cytoskeletal proteins in mutant protein phosphatase 2A transgenic mice
-
Schild, A., Ittner, L.M. & Gotz, J. Altered phosphorylation of cytoskeletal proteins in mutant protein phosphatase 2A transgenic mice. Biochem. Biophys. Res. Commun. 343, 1171-1178 (2006).
-
(2006)
Biochem. Biophys. Res. Commun
, vol.343
, pp. 1171-1178
-
-
Schild, A.1
Ittner, L.M.2
Gotz, J.3
-
16
-
-
33644853220
-
Enhanced vascular responses to adrenomedullin in mice overexpressing receptor-activity-modifying protein 2
-
Tam, C.W. et al. Enhanced vascular responses to adrenomedullin in mice overexpressing receptor-activity-modifying protein 2. Circ. Res. 98, 262-270 (2006).
-
(2006)
Circ. Res
, vol.98
, pp. 262-270
-
-
Tam, C.W.1
-
17
-
-
0025033653
-
Non-tolerance and differential susceptibility to diabetes in transgenic: Mice expressing major histocompatibility class II genes on pancreatic beta cells
-
Gotz, J., Eibel, H. & Kohler, G. Non-tolerance and differential susceptibility to diabetes in transgenic: Mice expressing major histocompatibility class II genes on pancreatic beta cells. Eur. J. Immunol. 20, 1677-1683 (1990).
-
(1990)
Eur. J. Immunol
, vol.20
, pp. 1677-1683
-
-
Gotz, J.1
Eibel, H.2
Kohler, G.3
-
18
-
-
33744928623
-
Impaired development of the Harderian gland in mutant protein phosphatase 2A transgenic mice
-
Schild, A. et al. Impaired development of the Harderian gland in mutant protein phosphatase 2A transgenic mice. Mech. Dev. 123 362-371 (2006).
-
(2006)
Mech. Dev
, vol.123
, pp. 362-371
-
-
Schild, A.1
-
19
-
-
0342803685
-
Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein
-
Probst, A. et al. Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein. Acta Neuropathol. (Berl) 99, 469-481 (2000).
-
(2000)
Acta Neuropathol. (Berl)
, vol.99
, pp. 469-481
-
-
Probst, A.1
-
20
-
-
0035800219
-
Compartmentalized tau hyperphospholylation and increased levels of kinases in transgenic mice
-
Gotz, J. & Nitsch, R.M. Compartmentalized tau hyperphospholylation and increased levels of kinases in transgenic mice. Neuroreport 12 2007-2016 (2001).
-
(2001)
Neuroreport
, vol.12
, pp. 2007-2016
-
-
Gotz, J.1
Nitsch, R.M.2
-
21
-
-
0034992339
-
Tau and transgenic animal models
-
Gotz, J. Tau and transgenic animal models. Brain Res. Brain Res. Rev. 35, 266-286 (2001).
-
(2001)
Brain Res. Brain Res. Rev
, vol.35
, pp. 266-286
-
-
Gotz, J.1
-
22
-
-
3142655729
-
Transgenic animal models of Alzheimer's disease and related disorders: Histopathology, behavior and therapy
-
Gotz, J. et al. Transgenic animal models of Alzheimer's disease and related disorders: Histopathology, behavior and therapy. Mol. Psychiatry 9, 664-683 (2004).
-
(2004)
Mol. Psychiatry
, vol.9
, pp. 664-683
-
-
Gotz, J.1
-
23
-
-
0033634813
-
Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP
-
Feng, G. et al. Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron 28, 41-51 (2000).
-
(2000)
Neuron
, vol.28
, pp. 41-51
-
-
Feng, G.1
-
24
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein
-
Games, D. et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein. Nature 373 523-527 (1995).
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
-
25
-
-
0034213718
-
High-Level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: Synaptotoxicity without plaque formation
-
Mucke, L. et al. High-Level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation. J. Neurosci. 20, 4050-4058 (2000).
-
(2000)
J. Neurosci
, vol.20
, pp. 4050-4058
-
-
Mucke, L.1
-
26
-
-
0029742199
-
Correlative memory deficits, abeta elevation, and amyloid plaques in transgenic mice
-
Hsiao, K. et al. Correlative memory deficits, abeta elevation, and amyloid plaques in transgenic mice. Science 274, 99-102 (1996).
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
-
27
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
-
Borchelt, D.R. et al. Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron 19, 939-945 (1997).
-
(1997)
Neuron
, vol.19
, pp. 939-945
-
-
Borchelt, D.R.1
-
28
-
-
0011444914
-
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-Like pathology
-
Sturchler-Pierrat, C. et al. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-Like pathology. Proc. Natl. Acad. Sci. USA 94, 13287-13292 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 13287-13292
-
-
Sturchler-Pierrat, C.1
-
29
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles. Intracellular abeta and synaptic dysfunction
-
Oddo, S. et al. Triple-transgenic model of Alzheimer's disease with plaques and tangles. Intracellular abeta and synaptic dysfunction. Neuron 39, 409-421 (2003).
-
(2003)
Neuron
, vol.39
, pp. 409-421
-
-
Oddo, S.1
-
30
-
-
0141707862
-
PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation
-
Richards, J.G. et al. PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation. J. Neurosci. 23, 8989-9003 (2003).
-
(2003)
J. Neurosci
, vol.23
, pp. 8989-9003
-
-
Richards, J.G.1
-
31
-
-
0345580607
-
Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's disease
-
Brion, J.P., Tremp, G. & Octave, J.N. Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's disease. Am. J. Pathol. 154, 255-270 (1999).
-
(1999)
Am. J. Pathol
, vol.154
, pp. 255-270
-
-
Brion, J.P.1
Tremp, G.2
Octave, J.N.3
-
32
-
-
0033230886
-
Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform
-
Ishihara, T. et al. Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform. Neuron 24, 751-762 (1999).
-
(1999)
Neuron
, vol.24
, pp. 751-762
-
-
Ishihara, T.1
-
33
-
-
0034426011
-
Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein
-
Lewis, J. et al. Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein. Nat. Genet. 25, 402-405 (2000).
-
(2000)
Nat. Genet
, vol.25
, pp. 402-405
-
-
Lewis, J.1
-
34
-
-
0034948975
-
Oligodendroglial tau filament formation in transgenic mice expressing G272V tau
-
Gotz, J. et al. Oligodendroglial tau filament formation in transgenic mice expressing G272V tau. Eur. J. Neurosci. 13, 2131-2140 (2001).
-
(2001)
Eur. J. Neurosci
, vol.13
, pp. 2131-2140
-
-
Gotz, J.1
-
35
-
-
0032786370
-
Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein
-
Spittaels, K. et al. Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein. Am. J. Pathol. 155, 2153-2165 (1999).
-
(1999)
Am. J. Pathol
, vol.155
, pp. 2153-2165
-
-
Spittaels, K.1
-
36
-
-
0035808361
-
Tau filament formation in transgenic mice expressing P301L tau
-
Gotz, J., Chen, F., Barmettler, R. & Nitsch, R.M. Tau filament formation in transgenic mice expressing P301L tau. J. Biol. Chem. 276, 529-534 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 529-534
-
-
Gotz, J.1
Chen, F.2
Barmettler, R.3
Nitsch, R.M.4
-
37
-
-
0036850725
-
Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein
-
Allen, B. et al. Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein. J. Neurosci. 22, 9340-9351 (2002).
-
(2002)
J. Neurosci
, vol.22
, pp. 9340-9351
-
-
Allen, B.1
-
38
-
-
0035664048
-
Formation of filamentous tau aggregations in transgenic mice expressing V337M human tau
-
Tanemura, K. et al. Formation of filamentous tau aggregations in transgenic mice expressing V337M human tau. Neurobiol. Dis. 8 1036-1045 (2001).
-
(2001)
Neurobiol. Dis
, vol.8
, pp. 1036-1045
-
-
Tanemura, K.1
-
39
-
-
0037108953
-
Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau
-
Tatebayashi, Y. et al. Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau. Proc. Natl. Acad. Sci. USA 99, 13896-13901 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 13896-13901
-
-
Tatebayashi, Y.1
-
40
-
-
0041803006
-
Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms
-
Andorfer, C. et al. Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms. J. Neurochem. 86, 582-590 (2003).
-
(2003)
J. Neurochem
, vol.86
, pp. 582-590
-
-
Andorfer, C.1
-
41
-
-
22344438508
-
Tau suppression in a neurodegenerative mouse model improves memory function
-
Santacruz, K. et al. Tau suppression in a neurodegenerative mouse model improves memory function. Science 309, 476-481 (2005).
-
(2005)
Science
, vol.309
, pp. 476-481
-
-
Santacruz, K.1
-
42
-
-
0029951776
-
Expression of APP in transgenic mice: A comparison of neuron-specific promoters
-
Andra, K. et al. Expression of APP in transgenic mice: A comparison of neuron-specific promoters. Neurobiol. Aging 17 183-190 (1996).
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 183-190
-
-
Andra, K.1
-
43
-
-
0033922371
-
Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT)
-
Truett, G.E. et al. Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT). Biotechniques 29 52-54 (2000).
-
(2000)
Biotechniques
, vol.29
, pp. 52-54
-
-
Truett, G.E.1
-
44
-
-
3442876436
-
Posttranslational modifications of tau - role in human tauopathies and modeling in transgenic animals
-
Chen, F., David, D., Ferrari, A. & Gotz, J. Posttranslational modifications of tau - role in human tauopathies and modeling in transgenic animals. Curr. Drug Targets 5, 503-515 (2004).
-
(2004)
Curr. Drug Targets
, vol.5
, pp. 503-515
-
-
Chen, F.1
David, D.2
Ferrari, A.3
Gotz, J.4
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