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Volumn 2, Issue 5, 2007, Pages 1206-1215

Pronuclear injection for the production of transgenic mice

Author keywords

[No Author keywords available]

Indexed keywords

DNA; TAU PROTEIN;

EID: 34250219566     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/nprot.2007.145     Document Type: Article
Times cited : (136)

References (44)
  • 1
    • 34047208826 scopus 로고    scopus 로고
    • Method for detection and identification of multiple chromosomal integration sites in transgenic animals created with Lentivirus
    • Bryda, E.C., Pearson, M., Agca, Y. & Bauer, B.A. Method for detection and identification of multiple chromosomal integration sites in transgenic animals created with Lentivirus. Biotechniques 41 715-719 (2006).
    • (2006) Biotechniques , vol.41 , pp. 715-719
    • Bryda, E.C.1    Pearson, M.2    Agca, Y.3    Bauer, B.A.4
  • 2
    • 33947308826 scopus 로고    scopus 로고
    • Generation of yeast artificial chromosome transgenic mice by intracytoplasmic sperm injection
    • Moreira, P.N., Pozueta, J., Giraldo, P., Gutierrez-Adan, A. & Montoliu, L. Generation of yeast artificial chromosome transgenic mice by intracytoplasmic sperm injection. Methods Mol. Biol. 349, 151-161 (2006).
    • (2006) Methods Mol. Biol , vol.349 , pp. 151-161
    • Moreira, P.N.1    Pozueta, J.2    Giraldo, P.3    Gutierrez-Adan, A.4    Montoliu, L.5
  • 3
    • 0018838415 scopus 로고
    • Translation of globin messenger RNA by the mouse ovum
    • Brinster, R.L., Chen, H.Y., Trumbauer, M.E. & Avarbock, M.R. Translation of globin messenger RNA by the mouse ovum. Nature 283, 499-501 (1980).
    • (1980) Nature , vol.283 , pp. 499-501
    • Brinster, R.L.1    Chen, H.Y.2    Trumbauer, M.E.3    Avarbock, M.R.4
  • 4
    • 0019847283 scopus 로고
    • Integration and stable germ line transmission of genes injected into mouse pronuclei
    • Gordon, J.W. & Ruddle, F.H. Integration and stable germ line transmission of genes injected into mouse pronuclei. Science 214, 1244-1246 (1981).
    • (1981) Science , vol.214 , pp. 1244-1246
    • Gordon, J.W.1    Ruddle, F.H.2
  • 5
    • 0019859395 scopus 로고
    • Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs
    • Brinster, R.L. et al. Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs. Cell 27, 223-231 (1981).
    • (1981) Cell , vol.27 , pp. 223-231
    • Brinster, R.L.1
  • 6
    • 0019855228 scopus 로고
    • Introduction of a rabbit beta-globin gene into the mouse germ line
    • Costantini, F. & Lacy, E. Introduction of a rabbit beta-globin gene into the mouse germ line. Nature 294, 92-94 (1981).
    • (1981) Nature , vol.294 , pp. 92-94
    • Costantini, F.1    Lacy, E.2
  • 7
    • 0019790422 scopus 로고
    • The human beta-globin gene and a functional viral thymidine kinase gene in developing mice
    • Wagner, E.F., Stewart, T.A. & Mintz, B. The human beta-globin gene and a functional viral thymidine kinase gene in developing mice. Proc. Natl. Acad. Sci. USA 78, 5016-5020 (1981).
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 5016-5020
    • Wagner, E.F.1    Stewart, T.A.2    Mintz, B.3
  • 8
    • 0000051454 scopus 로고
    • Microinjection of a rabbit beta-globin gene into zygotes and its subsequent expression in adult mice and their offspring
    • Wagner, T.E. et al. Microinjection of a rabbit beta-globin gene into zygotes and its subsequent expression in adult mice and their offspring. Proc. Natl. Acad. Sci. USA 78, 6376-6380 (1981).
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 6376-6380
    • Wagner, T.E.1
  • 9
    • 0032514680 scopus 로고    scopus 로고
    • Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Calpha
    • Gotz, J., Probst, A., Ehler, E., Hemmings, B. & Kues, W. Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Calpha. Proc. Natl. Acad. Sci. USA 95, 12370-12375 (1998).
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 12370-12375
    • Gotz, J.1    Probst, A.2    Ehler, E.3    Hemmings, B.4    Kues, W.5
  • 10
    • 0035152814 scopus 로고    scopus 로고
    • Neurotrophins are required for nerve growth during development
    • Tucker, K.L., Meyer, M. & Barde, Y.A. Neurotrophins are required for nerve growth during development. Nat. Neurosci. 4, 29-37 (2001).
    • (2001) Nat. Neurosci , vol.4 , pp. 29-37
    • Tucker, K.L.1    Meyer, M.2    Barde, Y.A.3
  • 12
    • 0028965635 scopus 로고
    • Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the Longest human brain tau isoform
    • Gotz, J. et al. Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the Longest human brain tau isoform. EMBO J. 14, 1304-1313 (1995).
    • (1995) EMBO J , vol.14 , pp. 1304-1313
    • Gotz, J.1
  • 13
    • 12144287410 scopus 로고    scopus 로고
    • Transgenic mice expressing the nucleoprotein of Borna disease virus in either neurons or astrocytes: Decreased susceptibility to homotypic infection and disease
    • Rauer, M., Gotz, J., Schuppli, D., Staeheli, P. & Hausmann, J. Transgenic mice expressing the nucleoprotein of Borna disease virus in either neurons or astrocytes: Decreased susceptibility to homotypic infection and disease. J. Virol. 78, 3621-3632 (2004).
    • (2004) J. Virol , vol.78 , pp. 3621-3632
    • Rauer, M.1    Gotz, J.2    Schuppli, D.3    Staeheli, P.4    Hausmann, J.5
  • 14
    • 0035851175 scopus 로고    scopus 로고
    • Reduced PP2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice
    • Kins, S. et al. Reduced PP2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice. J. Biol. Chem. 276, 38193-38200 (2001).
    • (2001) J. Biol. Chem , vol.276 , pp. 38193-38200
    • Kins, S.1
  • 15
    • 33646476174 scopus 로고    scopus 로고
    • Altered phosphorylation of cytoskeletal proteins in mutant protein phosphatase 2A transgenic mice
    • Schild, A., Ittner, L.M. & Gotz, J. Altered phosphorylation of cytoskeletal proteins in mutant protein phosphatase 2A transgenic mice. Biochem. Biophys. Res. Commun. 343, 1171-1178 (2006).
    • (2006) Biochem. Biophys. Res. Commun , vol.343 , pp. 1171-1178
    • Schild, A.1    Ittner, L.M.2    Gotz, J.3
  • 16
    • 33644853220 scopus 로고    scopus 로고
    • Enhanced vascular responses to adrenomedullin in mice overexpressing receptor-activity-modifying protein 2
    • Tam, C.W. et al. Enhanced vascular responses to adrenomedullin in mice overexpressing receptor-activity-modifying protein 2. Circ. Res. 98, 262-270 (2006).
    • (2006) Circ. Res , vol.98 , pp. 262-270
    • Tam, C.W.1
  • 17
    • 0025033653 scopus 로고
    • Non-tolerance and differential susceptibility to diabetes in transgenic: Mice expressing major histocompatibility class II genes on pancreatic beta cells
    • Gotz, J., Eibel, H. & Kohler, G. Non-tolerance and differential susceptibility to diabetes in transgenic: Mice expressing major histocompatibility class II genes on pancreatic beta cells. Eur. J. Immunol. 20, 1677-1683 (1990).
    • (1990) Eur. J. Immunol , vol.20 , pp. 1677-1683
    • Gotz, J.1    Eibel, H.2    Kohler, G.3
  • 18
    • 33744928623 scopus 로고    scopus 로고
    • Impaired development of the Harderian gland in mutant protein phosphatase 2A transgenic mice
    • Schild, A. et al. Impaired development of the Harderian gland in mutant protein phosphatase 2A transgenic mice. Mech. Dev. 123 362-371 (2006).
    • (2006) Mech. Dev , vol.123 , pp. 362-371
    • Schild, A.1
  • 19
    • 0342803685 scopus 로고    scopus 로고
    • Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein
    • Probst, A. et al. Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein. Acta Neuropathol. (Berl) 99, 469-481 (2000).
    • (2000) Acta Neuropathol. (Berl) , vol.99 , pp. 469-481
    • Probst, A.1
  • 20
    • 0035800219 scopus 로고    scopus 로고
    • Compartmentalized tau hyperphospholylation and increased levels of kinases in transgenic mice
    • Gotz, J. & Nitsch, R.M. Compartmentalized tau hyperphospholylation and increased levels of kinases in transgenic mice. Neuroreport 12 2007-2016 (2001).
    • (2001) Neuroreport , vol.12 , pp. 2007-2016
    • Gotz, J.1    Nitsch, R.M.2
  • 21
    • 0034992339 scopus 로고    scopus 로고
    • Tau and transgenic animal models
    • Gotz, J. Tau and transgenic animal models. Brain Res. Brain Res. Rev. 35, 266-286 (2001).
    • (2001) Brain Res. Brain Res. Rev , vol.35 , pp. 266-286
    • Gotz, J.1
  • 22
    • 3142655729 scopus 로고    scopus 로고
    • Transgenic animal models of Alzheimer's disease and related disorders: Histopathology, behavior and therapy
    • Gotz, J. et al. Transgenic animal models of Alzheimer's disease and related disorders: Histopathology, behavior and therapy. Mol. Psychiatry 9, 664-683 (2004).
    • (2004) Mol. Psychiatry , vol.9 , pp. 664-683
    • Gotz, J.1
  • 23
    • 0033634813 scopus 로고    scopus 로고
    • Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP
    • Feng, G. et al. Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron 28, 41-51 (2000).
    • (2000) Neuron , vol.28 , pp. 41-51
    • Feng, G.1
  • 24
    • 0028985574 scopus 로고
    • Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein
    • Games, D. et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein. Nature 373 523-527 (1995).
    • (1995) Nature , vol.373 , pp. 523-527
    • Games, D.1
  • 25
    • 0034213718 scopus 로고    scopus 로고
    • High-Level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: Synaptotoxicity without plaque formation
    • Mucke, L. et al. High-Level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation. J. Neurosci. 20, 4050-4058 (2000).
    • (2000) J. Neurosci , vol.20 , pp. 4050-4058
    • Mucke, L.1
  • 26
    • 0029742199 scopus 로고    scopus 로고
    • Correlative memory deficits, abeta elevation, and amyloid plaques in transgenic mice
    • Hsiao, K. et al. Correlative memory deficits, abeta elevation, and amyloid plaques in transgenic mice. Science 274, 99-102 (1996).
    • (1996) Science , vol.274 , pp. 99-102
    • Hsiao, K.1
  • 27
    • 0030833055 scopus 로고    scopus 로고
    • Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
    • Borchelt, D.R. et al. Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron 19, 939-945 (1997).
    • (1997) Neuron , vol.19 , pp. 939-945
    • Borchelt, D.R.1
  • 28
    • 0011444914 scopus 로고    scopus 로고
    • Two amyloid precursor protein transgenic mouse models with Alzheimer disease-Like pathology
    • Sturchler-Pierrat, C. et al. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-Like pathology. Proc. Natl. Acad. Sci. USA 94, 13287-13292 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 13287-13292
    • Sturchler-Pierrat, C.1
  • 29
    • 0042697305 scopus 로고    scopus 로고
    • Triple-transgenic model of Alzheimer's disease with plaques and tangles. Intracellular abeta and synaptic dysfunction
    • Oddo, S. et al. Triple-transgenic model of Alzheimer's disease with plaques and tangles. Intracellular abeta and synaptic dysfunction. Neuron 39, 409-421 (2003).
    • (2003) Neuron , vol.39 , pp. 409-421
    • Oddo, S.1
  • 30
    • 0141707862 scopus 로고    scopus 로고
    • PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation
    • Richards, J.G. et al. PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation. J. Neurosci. 23, 8989-9003 (2003).
    • (2003) J. Neurosci , vol.23 , pp. 8989-9003
    • Richards, J.G.1
  • 31
    • 0345580607 scopus 로고    scopus 로고
    • Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's disease
    • Brion, J.P., Tremp, G. & Octave, J.N. Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's disease. Am. J. Pathol. 154, 255-270 (1999).
    • (1999) Am. J. Pathol , vol.154 , pp. 255-270
    • Brion, J.P.1    Tremp, G.2    Octave, J.N.3
  • 32
    • 0033230886 scopus 로고    scopus 로고
    • Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform
    • Ishihara, T. et al. Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform. Neuron 24, 751-762 (1999).
    • (1999) Neuron , vol.24 , pp. 751-762
    • Ishihara, T.1
  • 33
    • 0034426011 scopus 로고    scopus 로고
    • Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein
    • Lewis, J. et al. Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein. Nat. Genet. 25, 402-405 (2000).
    • (2000) Nat. Genet , vol.25 , pp. 402-405
    • Lewis, J.1
  • 34
    • 0034948975 scopus 로고    scopus 로고
    • Oligodendroglial tau filament formation in transgenic mice expressing G272V tau
    • Gotz, J. et al. Oligodendroglial tau filament formation in transgenic mice expressing G272V tau. Eur. J. Neurosci. 13, 2131-2140 (2001).
    • (2001) Eur. J. Neurosci , vol.13 , pp. 2131-2140
    • Gotz, J.1
  • 35
    • 0032786370 scopus 로고    scopus 로고
    • Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein
    • Spittaels, K. et al. Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein. Am. J. Pathol. 155, 2153-2165 (1999).
    • (1999) Am. J. Pathol , vol.155 , pp. 2153-2165
    • Spittaels, K.1
  • 36
    • 0035808361 scopus 로고    scopus 로고
    • Tau filament formation in transgenic mice expressing P301L tau
    • Gotz, J., Chen, F., Barmettler, R. & Nitsch, R.M. Tau filament formation in transgenic mice expressing P301L tau. J. Biol. Chem. 276, 529-534 (2001).
    • (2001) J. Biol. Chem , vol.276 , pp. 529-534
    • Gotz, J.1    Chen, F.2    Barmettler, R.3    Nitsch, R.M.4
  • 37
    • 0036850725 scopus 로고    scopus 로고
    • Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein
    • Allen, B. et al. Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein. J. Neurosci. 22, 9340-9351 (2002).
    • (2002) J. Neurosci , vol.22 , pp. 9340-9351
    • Allen, B.1
  • 38
    • 0035664048 scopus 로고    scopus 로고
    • Formation of filamentous tau aggregations in transgenic mice expressing V337M human tau
    • Tanemura, K. et al. Formation of filamentous tau aggregations in transgenic mice expressing V337M human tau. Neurobiol. Dis. 8 1036-1045 (2001).
    • (2001) Neurobiol. Dis , vol.8 , pp. 1036-1045
    • Tanemura, K.1
  • 39
    • 0037108953 scopus 로고    scopus 로고
    • Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau
    • Tatebayashi, Y. et al. Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau. Proc. Natl. Acad. Sci. USA 99, 13896-13901 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 13896-13901
    • Tatebayashi, Y.1
  • 40
    • 0041803006 scopus 로고    scopus 로고
    • Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms
    • Andorfer, C. et al. Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms. J. Neurochem. 86, 582-590 (2003).
    • (2003) J. Neurochem , vol.86 , pp. 582-590
    • Andorfer, C.1
  • 41
    • 22344438508 scopus 로고    scopus 로고
    • Tau suppression in a neurodegenerative mouse model improves memory function
    • Santacruz, K. et al. Tau suppression in a neurodegenerative mouse model improves memory function. Science 309, 476-481 (2005).
    • (2005) Science , vol.309 , pp. 476-481
    • Santacruz, K.1
  • 42
    • 0029951776 scopus 로고    scopus 로고
    • Expression of APP in transgenic mice: A comparison of neuron-specific promoters
    • Andra, K. et al. Expression of APP in transgenic mice: A comparison of neuron-specific promoters. Neurobiol. Aging 17 183-190 (1996).
    • (1996) Neurobiol. Aging , vol.17 , pp. 183-190
    • Andra, K.1
  • 43
    • 0033922371 scopus 로고    scopus 로고
    • Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT)
    • Truett, G.E. et al. Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT). Biotechniques 29 52-54 (2000).
    • (2000) Biotechniques , vol.29 , pp. 52-54
    • Truett, G.E.1
  • 44
    • 3442876436 scopus 로고    scopus 로고
    • Posttranslational modifications of tau - role in human tauopathies and modeling in transgenic animals
    • Chen, F., David, D., Ferrari, A. & Gotz, J. Posttranslational modifications of tau - role in human tauopathies and modeling in transgenic animals. Curr. Drug Targets 5, 503-515 (2004).
    • (2004) Curr. Drug Targets , vol.5 , pp. 503-515
    • Chen, F.1    David, D.2    Ferrari, A.3    Gotz, J.4


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