Reoxygenation following hypoxia activates DNA-damage checkpoint signaling pathways that suppress cell-cycle progression in cultured human lymphocytes

FEBS Letters

Volumn 581, Issue 16, 2007, Pages 3005-3012

  Kim, Byeong Mo ^a   Choi, Jun Yeol ^a   Kim, Yang Jee ^a   Woo, Hae Dong ^a   Chung, Hai Won ^a  

^a Seoul National University   (South Korea)

Author keywords

Cytokinesis block proliferation index (CBPI); DNA damage checkpoint; Hypoxia reoxygenation (H R); Micronuclei; p53

Indexed keywords

CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 25C; CYTOKINE; GENE PRODUCT; NIBRIN; PROTEIN BAX; PROTEIN P21; PROTEIN P53; SERINE; SMC1 PROTEIN; THREONINE; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA DAMAGE; HUMAN; HUMAN TISSUE; HYPOXIA; LYMPHOCYTE; LYMPHOCYTE PROLIFERATION; MICRONUCLEUS; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REOXYGENATION; WESTERN BLOTTING;

CELL CYCLE; CELL CYCLE PROTEINS; CELL HYPOXIA; CELL PROLIFERATION; CELLS, CULTURED; CHROMOSOMAL PROTEINS, NON-HISTONE; DNA DAMAGE; DNA-BINDING PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; LYMPHOCYTES; NUCLEAR PROTEINS; OXYGEN; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 34250174556     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2007.05.053     Document Type: Article

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