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Volumn 178, Issue 12, 2007, Pages 7879-7889

Coexpression of IL-5 and eotaxin-2 in mice creates an eosinophil-dependent model of respiratory inflammation with characteristics of severe asthma

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; EOTAXIN; EOTAXIN 2; INTERLEUKIN 5; UNCLASSIFIED DRUG;

EID: 34250159031     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.178.12.7879     Document Type: Article
Times cited : (147)

References (50)
  • 1
    • 0020071965 scopus 로고
    • Identification by immunofluorescence of eosinophil granule major basic protein in lung tissues of patients with bronchial asthma
    • Filley, W. V., G. M. Kephardt, L. E. Holley, and G. J. Gleich. 1982. Identification by immunofluorescence of eosinophil granule major basic protein in lung tissues of patients with bronchial asthma, Lancet ii: 11-16.
    • (1982) Lancet , vol.2 , pp. 11-16
    • Filley, W.V.1    Kephardt, G.M.2    Holley, L.E.3    Gleich, G.J.4
  • 3
    • 0034124568 scopus 로고    scopus 로고
    • New aspects of degranulation and fates of airway mucosal eosinophils
    • Erjefält, J. S., and C. G. Persson. 2000. New aspects of degranulation and fates of airway mucosal eosinophils. Am. J. Respir. Crit. Care Med. 161: 2074-2085.
    • (2000) Am. J. Respir. Crit. Care Med , vol.161 , pp. 2074-2085
    • Erjefält, J.S.1    Persson, C.G.2
  • 4
    • 22944450858 scopus 로고    scopus 로고
    • Neutrophils and eosinophils: Clinical implications of their appearance, presence and disappearance in asthma and COPD
    • Watt, A. P., B. C. Schock, and M. Ennis. 2005. Neutrophils and eosinophils: clinical implications of their appearance, presence and disappearance in asthma and COPD. Curr. Drug Targets Inflamm. Allergy 4: 415-423.
    • (2005) Curr. Drug Targets Inflamm. Allergy , vol.4 , pp. 415-423
    • Watt, A.P.1    Schock, B.C.2    Ennis, M.3
  • 6
    • 85047693849 scopus 로고    scopus 로고
    • Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics
    • Flood-Page, P., A. Menzies-Gow, S. Phipps, S. Ying, A. Wangoo, M. S. Ludwig, N. Barnes, D. Robinson, and A. B. Kay. 2003. Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics. J. Clin. Invest. 112: 1029-1036.
    • (2003) J. Clin. Invest , vol.112 , pp. 1029-1036
    • Flood-Page, P.1    Menzies-Gow, A.2    Phipps, S.3    Ying, S.4    Wangoo, A.5    Ludwig, M.S.6    Barnes, N.7    Robinson, D.8    Kay, A.B.9
  • 7
    • 0029019404 scopus 로고
    • Eosinophil-associated inflammation in bronchial asthma: A connection to the nervous system
    • Gleich, G. J., D. B. Jacoby, and A. D. Fryer. 1995. Eosinophil-associated inflammation in bronchial asthma: a connection to the nervous system. Int. Arch. Allergy Immunol. 107: 205-207.
    • (1995) Int. Arch. Allergy Immunol , vol.107 , pp. 205-207
    • Gleich, G.J.1    Jacoby, D.B.2    Fryer, A.D.3
  • 8
    • 0030671371 scopus 로고    scopus 로고
    • Pretreatment with antibody to eosinophil major basic protein prevents hyperresponsiveness by protecting neuronal M2 muscarinic receptors in antigen-challenged guinea pigs
    • Evans, C. M., A. D. Fryer, D. B. Jacoby, G. J. Gleich, and R. W. Costello. 1997. Pretreatment with antibody to eosinophil major basic protein prevents hyperresponsiveness by protecting neuronal M2 muscarinic receptors in antigen-challenged guinea pigs. J. Clin. Invest. 100: 2254-2262.
    • (1997) J. Clin. Invest , vol.100 , pp. 2254-2262
    • Evans, C.M.1    Fryer, A.D.2    Jacoby, D.B.3    Gleich, G.J.4    Costello, R.W.5
  • 10
    • 33845540077 scopus 로고    scopus 로고
    • Animal models of asthma: Pro: allergic avoidance of animal (model(s)) is not an option
    • Shapiro, S. D. 2006. Animal models of asthma: pro: allergic avoidance of animal (model(s)) is not an option. Am. J. Respir. Crit. Care Med. 174: 1171-1173.
    • (2006) Am. J. Respir. Crit. Care Med , vol.174 , pp. 1171-1173
    • Shapiro, S.D.1
  • 11
    • 33845543076 scopus 로고    scopus 로고
    • The mouse trap: It still yields few answers in asthma
    • discussion 1176-1178
    • Wenzel, S., and S. T. Holgate. 2006. The mouse trap: it still yields few answers in asthma. Am. J. Respir. Crit. Care Med. 174: 1173-1176. discussion 1176-1178.
    • (2006) Am. J. Respir. Crit. Care Med , vol.174 , pp. 1173-1176
    • Wenzel, S.1    Holgate, S.T.2
  • 13
    • 0035424164 scopus 로고    scopus 로고
    • Extensive eosinophil degranulation and peroxidase-mediated oxidation of airway proteins do not occur in a mouse ovalbumin-challenge model of pulmonary inflammation
    • Denzler, K. L., M. T. Borchers, J. R. Crosby, G. Cieslewicz, E. M. Hines, J. P. Justice, S. A. Cormier, K. A. Lindenberger, W. Song, W. Wu, et al. 2001. Extensive eosinophil degranulation and peroxidase-mediated oxidation of airway proteins do not occur in a mouse ovalbumin-challenge model of pulmonary inflammation. J. Immunol. 167: 1672-1682.
    • (2001) J. Immunol , vol.167 , pp. 1672-1682
    • Denzler, K.L.1    Borchers, M.T.2    Crosby, J.R.3    Cieslewicz, G.4    Hines, E.M.5    Justice, J.P.6    Cormier, S.A.7    Lindenberger, K.A.8    Song, W.9    Wu, W.10
  • 14
    • 0033214919 scopus 로고    scopus 로고
    • Ying, S., D. S. Robinson, Q. Meng, L. T. Barata, A. R. McEuen, M. G. Buckley, A. F. Walls, P. W. Askenase, and A. B. Kay. 1999. C-C chemokines in allergen-induced late-phase cutaneous responses in atopic subjects: association of eotaxin with early 6-hour eosinophils, and of eotaxin-2 and monocyte chemoattractant protein-4 with the later 24-hour tissue eosinophilia, and relationship to basophils and other C-C chemokines (monocyte chemoattractant protein-3 and RANTES). J. Immunol. 163: 3976-3984.
    • Ying, S., D. S. Robinson, Q. Meng, L. T. Barata, A. R. McEuen, M. G. Buckley, A. F. Walls, P. W. Askenase, and A. B. Kay. 1999. C-C chemokines in allergen-induced late-phase cutaneous responses in atopic subjects: association of eotaxin with early 6-hour eosinophils, and of eotaxin-2 and monocyte chemoattractant protein-4 with the later 24-hour tissue eosinophilia, and relationship to basophils and other C-C chemokines (monocyte chemoattractant protein-3 and RANTES). J. Immunol. 163: 3976-3984.
  • 17
    • 0033195032 scopus 로고    scopus 로고
    • Eotaxin: An essential mediator of eosinophil trafficking into mucosal tissues
    • Rothenherg, M. E. 1999. Eotaxin: an essential mediator of eosinophil trafficking into mucosal tissues. Am. J. Respir. Cell Mol. Biol. 21: 291-295.
    • (1999) Am. J. Respir. Cell Mol. Biol , vol.21 , pp. 291-295
    • Rothenherg, M.E.1
  • 19
    • 26844435631 scopus 로고    scopus 로고
    • The eotaxin chemokines and CCR3 are fundamental regulators of allergen-induced pulmonary eosinophilia
    • Pope, S. M., N. Zimmermann, K. F. Stringer, M. L. Karow, and M. E. Rothenberg. 2005. The eotaxin chemokines and CCR3 are fundamental regulators of allergen-induced pulmonary eosinophilia. J. Immunol. 175: 5341-5350.
    • (2005) J. Immunol , vol.175 , pp. 5341-5350
    • Pope, S.M.1    Zimmermann, N.2    Stringer, K.F.3    Karow, M.L.4    Rothenberg, M.E.5
  • 21
    • 0034651784 scopus 로고    scopus 로고
    • The effect of IL-5 and eotaxin expression in the lung on eosinophil trafficking and degranulation and the induction of bronchial hyperreactivity
    • Mould, A. W., A. J. Ramsay, K. I. Matthaei, I. G. Young, M. E. Rothenberg, and P. S. Foster. 2000. The effect of IL-5 and eotaxin expression in the lung on eosinophil trafficking and degranulation and the induction of bronchial hyperreactivity. J. Immunol. 164: 2142-2150.
    • (2000) J. Immunol , vol.164 , pp. 2142-2150
    • Mould, A.W.1    Ramsay, A.J.2    Matthaei, K.I.3    Young, I.G.4    Rothenberg, M.E.5    Foster, P.S.6
  • 25
    • 0036721776 scopus 로고    scopus 로고
    • Eotaxin (CCL11) and eotaxin-2 (CCL24) induce recruitment of eosinophils, hasophils, neutrophils, and macrophages as well as features of early-and late-phase allergic reactions following cutaneous injection in human atopic and nonatopic volunteers
    • Menzies-Gow, A., S. Ying, I. Sabroe, V. L. Stubbs, D. Soler, T. J. Williams, and A. B. Kay. 2002. Eotaxin (CCL11) and eotaxin-2 (CCL24) induce recruitment of eosinophils, hasophils, neutrophils, and macrophages as well as features of early-and late-phase allergic reactions following cutaneous injection in human atopic and nonatopic volunteers. J. Immunol. 160: 2712-2718.
    • (2002) J. Immunol , vol.160 , pp. 2712-2718
    • Menzies-Gow, A.1    Ying, S.2    Sabroe, I.3    Stubbs, V.L.4    Soler, D.5    Williams, T.J.6    Kay, A.B.7
  • 26
    • 0026738951 scopus 로고
    • Cell-specific expression of a Clara cell secretory protein-human growth hormone gene in the bronchiolar epithelium of transgenic mice
    • Hackett, B. P., and J. D. Gitlin. 1992. Cell-specific expression of a Clara cell secretory protein-human growth hormone gene in the bronchiolar epithelium of transgenic mice. Proc. Natl. Acad. Sci. USA 89: 9079-9083.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9079-9083
    • Hackett, B.P.1    Gitlin, J.D.2
  • 28
    • 0031068013 scopus 로고    scopus 로고
    • Expression of IL-5 in thymocytes/T cells leads to the development of a massive eosinophilia, extramedullar eosinophilopoiesis, and unique histopathologies
    • Lee, N. A., M. P. McGarry, K. A. Larson, M. A. Horton, A. B. Kristensen, and J. J. Lee. 1997. Expression of IL-5 in thymocytes/T cells leads to the development of a massive eosinophilia, extramedullar eosinophilopoiesis, and unique histopathologies. J. Immunol. 158: 1332-1344.
    • (1997) J. Immunol , vol.158 , pp. 1332-1344
    • Lee, N.A.1    McGarry, M.P.2    Larson, K.A.3    Horton, M.A.4    Kristensen, A.B.5    Lee, J.J.6
  • 30
    • 0028963807 scopus 로고
    • Inherited thrombocytopenia caused by reduced platelet production in mice with the gunmetal pigment gene mutation
    • Novak, E. K., M. Reddington, L. Zhen, P. E. Stenberg, C. W. Jackson, M. P. McGarry, and R. T. Swank. 1995. Inherited thrombocytopenia caused by reduced platelet production in mice with the gunmetal pigment gene mutation. Blood 85: 1781-1789.
    • (1995) Blood , vol.85 , pp. 1781-1789
    • Novak, E.K.1    Reddington, M.2    Zhen, L.3    Stenberg, P.E.4    Jackson, C.W.5    McGarry, M.P.6    Swank, R.T.7
  • 31
    • 0035986018 scopus 로고    scopus 로고
    • Airway and tissue mechanics in a murine model of asthma: Alveolar capsule vs. forced oscillations
    • Tomioka, S., J. H. Bates, and C. G. Irvin. 2002. Airway and tissue mechanics in a murine model of asthma: alveolar capsule vs. forced oscillations. J. Appl. Physiol. 93: 263-270.
    • (2002) J. Appl. Physiol , vol.93 , pp. 263-270
    • Tomioka, S.1    Bates, J.H.2    Irvin, C.G.3
  • 32
    • 0030835266 scopus 로고    scopus 로고
    • 5-Lipoxygenase products are necessary for ovalbumin-induecd airway responsiveness in mice
    • Irvin, C. G., Y. P. Tu, J. R. Sheller, and C. D. Funk. 1997. 5-Lipoxygenase products are necessary for ovalbumin-induecd airway responsiveness in mice. Am. J. Physiol. 272: L1053-L1058.
    • (1997) Am. J. Physiol , vol.272
    • Irvin, C.G.1    Tu, Y.P.2    Sheller, J.R.3    Funk, C.D.4
  • 33
    • 33847142850 scopus 로고    scopus 로고
    • CD69 expression on airway eosinophils and airway inflammation in a murine model of asthma
    • Wang, H. Y., H. H. Shen, J. J. Lee, and N. A. Lee. 2006. CD69 expression on airway eosinophils and airway inflammation in a murine model of asthma. Chin. Med. J. 119: 1983-1990.
    • (2006) Chin. Med. J , vol.119 , pp. 1983-1990
    • Wang, H.Y.1    Shen, H.H.2    Lee, J.J.3    Lee, N.A.4
  • 34
    • 0027507513 scopus 로고
    • CD69 is expressed by human eosinophils activated in vivo in asthma and in vitro by cytokines
    • Hartnell, A., D. S. Robinson, A. B. Kay, and A. J. Wardlaw. 1993. CD69 is expressed by human eosinophils activated in vivo in asthma and in vitro by cytokines. Immunology 80: 281-286.
    • (1993) Immunology , vol.80 , pp. 281-286
    • Hartnell, A.1    Robinson, D.S.2    Kay, A.B.3    Wardlaw, A.J.4
  • 35
    • 0033555962 scopus 로고    scopus 로고
    • Activated eosinophils are the major source of Th2-associated cytokines in the schistosome granuloma
    • Rumbley, C. A., H. Sugaya, S. A. Zekavat, M. El Refaei, P. J. Perrin, and S. M. Phillips. 1999. Activated eosinophils are the major source of Th2-associated cytokines in the schistosome granuloma. J. Immunol. 162: 1003-1009.
    • (1999) J. Immunol , vol.162 , pp. 1003-1009
    • Rumbley, C.A.1    Sugaya, H.2    Zekavat, S.A.3    El Refaei, M.4    Perrin, P.J.5    Phillips, S.M.6
  • 37
    • 0028220844 scopus 로고
    • Human eosinophils in vitro: An ultrastructural morphology primer
    • Dvorak, A. M., and T. Ishizaka. 1994. Human eosinophils in vitro: an ultrastructural morphology primer. Histol. Histopathol. 9: 339-374.
    • (1994) Histol. Histopathol , vol.9 , pp. 339-374
    • Dvorak, A.M.1    Ishizaka, T.2
  • 38
    • 0031983564 scopus 로고    scopus 로고
    • Bronchiolitis: Pathologic considerations
    • Colby, T. V. 1998. Bronchiolitis: pathologic considerations. Am. J. Clin. Pathol. 109: 101-109.
    • (1998) Am. J. Clin. Pathol , vol.109 , pp. 101-109
    • Colby, T.V.1
  • 40
    • 2942620721 scopus 로고    scopus 로고
    • Discontinuous Percoll gradient centrifugation combined with immunomagnetic separation obviates the need for erythrocyte lysis and yields isolated eosinophils with minimal granule abnormalities
    • Malm-Erjefalt, M., T. R. Stevens, C. G. Persson, and J. S. Erjefalt. 2004. Discontinuous Percoll gradient centrifugation combined with immunomagnetic separation obviates the need for erythrocyte lysis and yields isolated eosinophils with minimal granule abnormalities. J. Immunol. Methods 288: 99-109.
    • (2004) J. Immunol. Methods , vol.288 , pp. 99-109
    • Malm-Erjefalt, M.1    Stevens, T.R.2    Persson, C.G.3    Erjefalt, J.S.4
  • 42
    • 0037114761 scopus 로고    scopus 로고
    • Stem cell factor induces eosinophil activation and degranulation: Mediator release and gene array analysis
    • Oliveira, S. H., D. D. Taub, J. Nagel, R. Smith, C. M. Hogaboam, A. Berlin, and N. W. Lukacs. 2002. Stem cell factor induces eosinophil activation and degranulation: mediator release and gene array analysis. Blood 100: 4291-4297.
    • (2002) Blood , vol.100 , pp. 4291-4297
    • Oliveira, S.H.1    Taub, D.D.2    Nagel, J.3    Smith, R.4    Hogaboam, C.M.5    Berlin, A.6    Lukacs, N.W.7
  • 43
    • 0034679559 scopus 로고    scopus 로고
    • Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction
    • Blackburn, M. R., J. B. Volmer, J. L. Thrasher, H. Zhong, J. R. Crosby, J. J. Lee, and R. E. Kellems. 2000. Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction. J. Exp. Med. 192: 159-170.
    • (2000) J. Exp. Med , vol.192 , pp. 159-170
    • Blackburn, M.R.1    Volmer, J.B.2    Thrasher, J.L.3    Zhong, H.4    Crosby, J.R.5    Lee, J.J.6    Kellems, R.E.7
  • 44
    • 18744422315 scopus 로고    scopus 로고
    • Degranulation of eosinophils mediated by intercellular adhesion molecule-1 and its ligands is involved in adhesion molecule expression on endothelial cells-selective induction of VCAM-1
    • Chibara, J., T. Yamamoto, H. Kayaba, T. Kakazu, D. Kurachi, J. Yamamoto, S. Iwasa, K. Iida, O. Urayama, and Y. Kobayashi. 1999. Degranulation of eosinophils mediated by intercellular adhesion molecule-1 and its ligands is involved in adhesion molecule expression on endothelial cells-selective induction of VCAM-1. J. Allergy Clin. Immunol. 103: S452-S456.
    • (1999) J. Allergy Clin. Immunol , vol.103
    • Chibara, J.1    Yamamoto, T.2    Kayaba, H.3    Kakazu, T.4    Kurachi, D.5    Yamamoto, J.6    Iwasa, S.7    Iida, K.8    Urayama, O.9    Kobayashi, Y.10
  • 45
    • 0034099788 scopus 로고    scopus 로고
    • Is allergen exposure the major primary cause of asthma?
    • Pearce, N., J. Douwes, and R. Beasley. 2000. Is allergen exposure the major primary cause of asthma? Thorax 55: 424-431.
    • (2000) Thorax , vol.55 , pp. 424-431
    • Pearce, N.1    Douwes, J.2    Beasley, R.3
  • 47
    • 4444315075 scopus 로고    scopus 로고
    • Effects of interleukin-1β, interleukin-13 and transforming growth factor-β on gene expression in human airway smooth muscle using gene microarrays
    • Jarai, G., M. Sukkar, S. Garrett, N. Duroudier, J. Westwick, I. Adcock, and K. F. Chung. 2004. Effects of interleukin-1β, interleukin-13 and transforming growth factor-β on gene expression in human airway smooth muscle using gene microarrays. Eur. J. Pharmacol. 497: 255-265.
    • (2004) Eur. J. Pharmacol , vol.497 , pp. 255-265
    • Jarai, G.1    Sukkar, M.2    Garrett, S.3    Duroudier, N.4    Westwick, J.5    Adcock, I.6    Chung, K.F.7
  • 48
    • 3242807236 scopus 로고    scopus 로고
    • Cysteinyl leukotrienes and their receptors: Cellular distribution and function in immune and inflammatory responses
    • Kanaoka, Y., and J. A. Boyce. 2004. Cysteinyl leukotrienes and their receptors: cellular distribution and function in immune and inflammatory responses. J. Immunol. 173: 1503-1510.
    • (2004) J. Immunol , vol.173 , pp. 1503-1510
    • Kanaoka, Y.1    Boyce, J.A.2
  • 49
    • 0021331196 scopus 로고
    • Arachidonic acid metabolism in normal and hypereosinophilic syndrome human eosinophils: Generation of leukotrienes B4, C4, D4 and 15-lipoxygenase products
    • Henderson, W. R., J. B. Harley, and A. S. Fauci. 1984. Arachidonic acid metabolism in normal and hypereosinophilic syndrome human eosinophils: generation of leukotrienes B4, C4, D4 and 15-lipoxygenase products. Immunology 51: 679-686.
    • (1984) Immunology , vol.51 , pp. 679-686
    • Henderson, W.R.1    Harley, J.B.2    Fauci, A.S.3
  • 50
    • 0027509685 scopus 로고
    • The effect of human eosinophil granule major basic protein on airway responsiveness in the rat in vivo: A comparison with polycations
    • Uchida, D. A., S. J. Ackerman, A. J. Coyle, G. L. Larsen, P. F. Weller, J. Freed, and C. G. Irvin. 1993. The effect of human eosinophil granule major basic protein on airway responsiveness in the rat in vivo: a comparison with polycations. Am. Rev. Respir. Dis. 147: 982-988.
    • (1993) Am. Rev. Respir. Dis , vol.147 , pp. 982-988
    • Uchida, D.A.1    Ackerman, S.J.2    Coyle, A.J.3    Larsen, G.L.4    Weller, P.F.5    Freed, J.6    Irvin, C.G.7


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