Pretreatment with antibody to eosinophil major basic protein prevents hyperresponsiveness by protecting neuronal M2 muscarinic receptors in antigen-challenged guinea pigs

Journal of Clinical Investigation

Volumn 100, Issue 9, 1997, Pages 2254-2262

  Evans, Christopher M ^a   Fryer, Allison D ^a   Jacoby, David B ^a,b   Gleich, Gerald J ^c,d   Costello, Richard W ^a,b  

^a Johns Hopkins University   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MAYO GRADUATE SCHOOL   (United States)

^d MAYO CLINIC   (United States)

Author keywords

Airway hyperresponsiveness; Antigen challenge; Eosinophils; Major basic protein; Muscarinic receptors; Parasympathetic nerves

Indexed keywords

ANTIBODY; ANTIGEN; MAJOR BASIC PROTEIN; MUSCARINIC M2 RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; EOSINOPHIL; GUINEA PIG; NONHUMAN; PARASYMPATHETIC NERVE; PRIORITY JOURNAL; PROVOCATION TEST;

EID: 0030671371     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119763     Document Type: Article

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