Eosinophils retain their granule major basic protein in a murine model of allergic pulmonary inflammation

American Journal of Respiratory Cell and Molecular Biology

Volumn 18, Issue 4, 1998, Pages 463-470

  Stelts, D ^b   Egan, R W ^b   Falcone, A ^b   Garlisi, C G ^b   Gleich, G J ^b   Kreutner, W ^b   Kung, T T ^b   Nahrebne, D K ^b   Chapman, R W ^b   Minnicozzi, M ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; MURINAE;

EOSINOPHIL GRANULE PROTEIN; PLASMA PROTEIN; RIBONUCLEASE;

ANIMAL; ARTICLE; CELL FREE SYSTEM; CHEMISTRY; CYTOLOGY; DISEASE MODEL; EOSINOPHIL; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; INFLAMMATION; LUNG; LUNG LAVAGE; MALE; METABOLISM; MOUSE; PATHOLOGY; PNEUMONIA; RESPIRATORY TRACT ALLERGY;

ANIMALS; BLOOD PROTEINS; BRONCHOALVEOLAR LAVAGE FLUID; CELL-FREE SYSTEM; DISEASE MODELS, ANIMAL; EOSINOPHIL GRANULE PROTEINS; EOSINOPHILS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LUNG; MALE; MICE; PNEUMONIA; RESPIRATORY HYPERSENSITIVITY; RIBONUCLEASES;

EID: 0032038571     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.18.4.2957     Document Type: Article

References (39)

1. Aalbers, R., J. G. R. de Monchy, H. F. Kauffman, M. Smith, Y. Hoekstra, B. Vrugt, and W. Timens. 1993. Dynamics of eosinophil infiltration in the bronchial mucosa before and after the late asthmatic reaction. Eur. Respir. J. 6:840-847.
2. Am, J. P., and T. K. Lee. 1992. The pathobiology of bronchial asthma. Adv. Immunol. 51:323-382.
3. Kaneko, M., M. C. Swanson, G. J. Gleich, and H. Kita. 1995. Allergen-specific IgG1 and IgG3 through FcRII induce eosinophil degranulation. J. Clin. Invest. 95:2813-2821.
4. Kroegel, C., T. Yukawa, G. Dent, P. Venge, K. F. Chung, and P. J. Barnes. 1989. Stimulation of degranulation from human eosinophils by platelet activating factor. J. Immunol. 142:3518-3526.
5. Abu-Ghazaleh, R. I., S. L. Dunnelte, D. A. Loegering, J. L. Checkel, H. Kita, L. L. Thomas, and G. J. Gleich. 1992. Eosinophil granule proteins in peripheral blood granulocytes. J. Leuk. Biol. 52:611-618.
6. Frigas, E., and G. J. Gleich. 1986. The eosinophil and pathophysiology of asthma. J. Allergy Clin. Immunol. 77:527-537.
7. Spry, C. J. F. 1988. Eosinophil activation, cytotoxicity, and interactions. In Eosinophils: A Comprehensive Guide to the Scientific and Medical Literature. C. J. F. Spry, editor. Oxford University Press, New York, 103-122.
8. Holgate, S. T., W. R. Roche, and M. K. Church. 1991. The role of the eosinophil in asthma. Am. Rev. Respir. Dis. 143:S66-S70.
9. Urchida, D. A., A. J. Coyle, S. J. Ackerman, P. F. Weller, G. L. Larsen, and C. G. Irvin. 1993. The effects of human eosinophil granule major basic protein on rat airways responsiveness in vivo: a comparison with polycations. Am. Rev. Respir. Dis. 147:982-988.
10. Frigas, E., D. A. Loegering, and G. J. Gleich. 1980. Cytotoxic effects of the guinea pig eosinophil major basic protein on tracheal epithelium. Lab. Invest. 42:35-43.
11. Minnicozzi, M., W. N. Duran, G. J. Gleich, and R. W. Egan. 1994. Eosinophil granule proteins increase microvascular macromolecular transport in the hamster cheek pouch. J. Immunol. 153:2664-2670.
12. Kung, T. T., H. Jones, G. K. Adams, S. P. Umland, W. Kreutner, R. W. Egan, R. W. Chapman, and A. S. Watnick. 1994. Characterization of a murine model of allergic pulmonary inflammation. Int. Arch. Aller. Immunol. 105:83-90.
13. + T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia. Am. J. Respir. Cell Mol. Biol. 10:587-593.
14. Hessel, E. M., A. J. M. Van Oosterhout, C. L. Hofstra, J. J. DeBie, J. Garssen, H. V. Loveren, A. K. C. P. Verheyen, H. F. J. Savelkoul, and F. P. Nijkamp. 1995. Bronchoconstriction and airway hyperresponsiveness after ovalbumin inhalation in sensitized mice. Eur. J. Pharmacol. 293:410-412.
15. Lellouch-Tubiana, A., J. Lefort, M.-T. Simon, A. Pfister, and B. B. Vargaftig. 1988. Eosinophil recruitment into the guinea pig lungs after PAF-acether and allergen administration. Am. Rev. Respir. Dis. 137:948-954.
16. Litchfield, T. M., and T. K. Lee. 1992. Asthma: cells and cytokines. J. Asthma 29:181-191.
17. Kung, T. T., D. M. Stelts, J. A. Zurcher, G. K. Adams, R. W. Egan, W. Kreutner, A. S. Watnick, H. Jones, and R. W. Chapman. 1995. Involvement of IL-5 in a murine model of allergic pulmonary inflammation: prophylactic and therapeutic effect of an anti-IL-5 antibody. Am. J. Respir. Cell Mol. Biol. 13:360-365.
18. Shi, H., S. Qin, G. Huang, Y. Chen, C. Xiao, H. Xu, G. Liang, Z. Xie, X. Qin, J. Wu, G. Li, and C. Zhang. 1997. Infiltration of eosinophils into the lung of asthmatic airways caused hy interleukin 5. Am. J. Respir. Cell Mol. Biol. 16:220-224.
19. Ohnishi, T., H. Kita, D. Weiler, S. Sur, J. B. Sedgwick, W. J. Calhoun, W. W. Busse, J. S. Abrams, and G. J. Gleich. 1993. IL-5 is the predominant eosinophil active cytokine in the antigen-induced pulmonary late phase reaction. Am. Rev. Respir. Dis. 147:901-907.
20. Garlisi, C. G., A. Falcone, J. A. Hey, T. M. Paster, X. Fernandez, C. A. Rizzo, M. Minnicozzi, H. Jones, M. M. Billah, R. W. Egan, and S. P. Umland. 1997. Airway eosinophils, T cells, Th2-type cytokine mRNA and hyperreactivity in response to aerosol challenge of allergic mice with previously established pulmonary inflammation. Am. J. Respir. Cell Mol. Biol. 17:642-651.
21. Thompson, S. W. 1996. Selecled Histochemical and Histopathological Methods. Charles C. Thomas, Springfield, IL.
22. Sheehan, D. C. and B. B. Hrapchak. 1980. Theory and Practice of Histotechnology. Batelle Press, Columbus, OH.
23. Filley, W. V., S. J. Ackerman, and G. J. Gleich. 1981. An immunoflourescent method for specific staining of eosinophil granule major basic protein. J. Immunol. Methods 47:227-238.
24. Beesley, J. E. 1992. Immunogold probes for light microscopy. In Methods in Molecular Biology, Vol. 10. M. M. Manson, editor. Humana Press, Inc., Totowa, NJ, 169-176.
25. Korsgren, M., J. S. Erjefalt, O. Korsgren, F. Sundler, and C. G. A. Persson. 1997. Allergic eosinophil-rich inflammation develops in lungs and airways of B cell-deficient mice. J. Exp. Med. 185:885-892.
26. Eum, S. Y., S. Haile, J. Lefort, M. Huerre, and B. B. Vargaftig. 1995. Eosinophil recruitment into the respiratory epithelium following antigenic challenge in hyper-IgE mice is accompanied by interleukin 5-dependent bronchial hyperresponsiveness. Proc. Natl. Acad. Sci. USA 92:12290-12294.
27. 1-sensitized guinea pigs. J. Pharmacol. Exp. Ther. 264:922-929.
28. Ohnishi, T., S. Sur, D. S. Collins, J. E. Fish, G. J. Gleich, and S. P. Peters. 1993. Eosinophil survival activity identified as interleukin-5 is associated with eosinophil recruitment and degranulation and lung injury twenty-four hours after segmental antigen lung challenge. J. Allergy Clin. Immunol. 92:607-615.
29. Dubuequoi, S., P. Desreumaux, A. Janin, O. Klien, M. Goldman, J. Tavernier, A. Capron, and M. Capron. 1994. Interleukin 5 synthesis by eosinophils: association with granules and immunoglobulin-dependent secretion. J. Exp. Med. 179:703-708.
30. Garlisi, C. G., A. Falcone, M. M. Billah, R. W. Egan, and S. P. Umland. 1996. T cells are the predominant source of interleukin-5 but not interleukin-4 mRNA expression in the lungs of antigen-challenged allergic mice. Am. J. Respir. Cell Mol. Biol. 15:420-428.
31. Lefort, J., M. Nahori, C. Ruffie, B. B. Vargaftig, and M. Pretolani. 1996. In vivo neutralization of eosinophil-derived major basic protein inhibits antigen-induced bronchial hyperactivity in sensitized guinea pigs. J. Clin. Invest. 97:1117-1121.
32. Gundel, R. H., G. Lets, and G. J. Gleich. 1991. Human eosinophil major basic protein induces airway constriction and airway hyperresponsiveness in nonhuman primates. J. Clin. Invest. 87:1470-1473.
33. Frigas, E., D. A. Loegering, G. O. Solley, G. M. Farrow, and G. J. Gleich. 1981. Elevated levels of the eosinophil granule major basic protein in the sputum of patients with bronchial asthma. Mayo Clin. Proc. 56:345-353.
34. Jacoby, D. B., G. J. Gleich, and A. D. Fryer. 1993. Human eosinophil major basic protein is an endogenous allosteric antagonist at the inhibitory muscarinic M2 receptor. J. Clin. Invest. 91:1314-1318.
35. Gleich, G. J., S. Motojima, E. Frigas, G. M. Kephart, T. Fujisawa, and L. P. Kravis. 1987. The eosinophilic leukocyte and the pathology of fatal bronchial asthma: evidence for pathologic heterogeneity. J. Allergy Clin. Immunol. 80:412-414.
36. Barnes, P. J., K. F. Chung, and C. P. Page. 1988. Inflammatory mediators and asthma. Pharm. Rev. 40:49-84.
37. Barnes, P. J., and F. Y. Liew. 1995. Nitric oxide and asthmatic inflammation. Immunol. Today 16:128-130.
38. Feder, L. S., D. Stelts, R. W. Chapman, D. Manfra, Y. Crawley, H. Jones, M. Minnicozzi, X. Fernandez, T. Paster, R. W. Egan, W. Kreutner, and T. T. Kung. 1997. Role of nitric oxide on eosinophilic lung inflammation in allergic mice. Am. J. Respir. Cell Mol. Biol. 17:436-442.
39. Kung, T. T., D. Stelts, J. A. Zurcher, H. Jones, S. P. Umland, W. Kreutner, R. W. Egan, and R. W. Chapman. 1995. Mast cells modulate allergic pulmonary eosinophilia in mice. Am. J. Respir. Cell Mol. Biol. 12:404-409.