Caspase inhibition during apoptosis causes abnormal signalling and developmental aberrations in Drosophila

Development

Volumn 131, Issue 22, 2004, Pages 5591-5598

  Pérez Garijo, Ainhoa ^a   Martín, Francisco A ^a   Morata, Ginés ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

Apoptosis; Caspase activity; dpp; Drosophila; wg; Wing disc

Indexed keywords

CASPASE; CASPASE INHIBITOR; PROTEIN P53;

APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL DEATH; CELL PROLIFERATION; CHROMOSOME ABERRATION; DROSOPHILA; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION REGULATION; HEAT SHOCK RESPONSE; IMAGINAL DISC; MAMMAL CELL; MORPHOLOGICAL TRAIT; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WILD TYPE; X IRRADIATION;

ANIMALS; APOPTOSIS; CASPASES; CELL LINEAGE; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; HEAT; INHIBITOR OF APOPTOSIS PROTEINS; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; VIRAL PROTEINS; WING;

MAMMALIA;

EID: 10344258000     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.01432     Document Type: Article

References (41)

1. Bergmann, A., Yang, A. Y. and Srivastava, M. (2003). Regulators of IAP function: coming to grips with the grim reaper. Curr. Opin. Cell Biol. 15, 717-724.
2. Bienz, M. and Clever, H. (2000). Linking colorectal cancer to Wnt signalling. Cell 103, 311-320.
3. Blackman, R. K., Sanicola, M., Raftery, L., Gillevet, T. and Gelbart, W. M. (1991). An extensive 3′ cis-regulatory region directs the imaginal disk expression of decapentaplegic, a member of the TGF-β family in Drosophila. Development 111, 657-665.
4. Brand, A. H. and Perrimon, N. (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.
5. Brodsky, M. H., Nordstrom, W., Tsang, G., Kwan, E., Rubin, G. and Abrams, J. M. (2000). Drosophila p53 binds a damage response element at the reaper locus Cell 101, 103-113.
6. Bryant, P. J. (1971). Regeneration and duplication following operations in situ on the imaginal discs of Drosophila melanogaster. Dev. Biol. 26, 637-651.
7. Burke, R. and Basler, K. (1996). Dpp receptors are autonomously required for cell proliferation in the entire developing Drosophila wing. Development 122, 2261-2269.
8. Calleja, M., Moreno, E., Pelaz, S. and Morata, G. (1996). Visualization of gene expression in living adult Drosophila. Science 274, 252-255.
9. Chen, P., Nordstrom, W., Gish, B. and Abrams, J. M. (1996). grim, a novel cell death gene in Drosophila. Genes Dev. 10, 1773-1782.
10. Clem, R. J., Fechneimer, M. and Miller, L. K. (1991). Prevention of apoptosis by a baculovirus gene during infection of insect cells. Science 254, 1388-1390.
11. Danial, N. N. and Korsmeyer, S. (2004). Cell death: critical control points. Cell 116, 205-219.
12. Gibson, M. C. and Schubiger, G. (1999). Hedgehog is required for activation of engrailed during regeneration of fragmented Drosophila imaginal discs. Development 126, 1591-1599.
13. Goyal. L. (2001). Cell death inhibition: keeping caspases in check. Cell 104, 805-808.
14. Goyal, L., McCall, K., Agapite, J., Hartwieg, E. and Steller, H. (2000). Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function. EMBO J. 19, 589-597.
15. Grether, M. E., Abrams, J. M., Agapite, J., White, K. and Steller, H. (1995). The head involution defective gene of Drosophila melanogaster functions in programmed cell death. Genes Dev. 9, 1694-1708.
16. Hanahan, D. and Weinberg. R. A. (2000). The hallmarks of cancer. Cell 100, 57-70.
17. Hay, B. A., Wolff, T. and Rubin, G. (1994). Expression of baculovirus P35 prevents cell death in Drosophila. Development 120, 2121-2129.
18. Haynie, J. L. and Bryant, P J. (1977). The effects of X-rays on the proliferation dynamics of cells in the imaginal wing disc of Drosophila melanogaster Rouxs Arch. 183, 85-100.
19. Hu, J. R., Guo, M. and Hay, B. A. (2004). Compensatory proliferation induced by cell death in the Drosophila wing disc requires activity of the apical cell death caspase Drone in a nonapoptotic role. Curr. Biol. 14, 1262-1266.
20. Jacobson, M. D., Weil, M. and Raff, M. (1997). Programmed cell death in animal development Cell 88, 347-354.
21. Lawrence, P A. and Struhl, G. (1996). Morphogens, compartments and pattern: lessons from Drosophila. Cell 85, 951-961.
22. Lohmann, I., McGinnis, N., Bodmer, M. and McGinnis, W. (2002). The Drosophila Hox gene deformed sculpts head morphology via direct regulation of the apoptosis activator reaper. Cell 110, 457-466.
23. Martin-Castellanos, C. and Edgar, B. A. (2002). A characterization of the effects of Dpp signaling on cell growth and proliferation in the Drosophila wing. Development 129, 1003-1013.
24. Martín, F. A., Pérez-Garijo, A., Moreno, E. and Morata, G. (2004). The Brinker gradient controls wing growth in Drosophila. Development 131, 4921-4930.
25. Milan, M., Campuzano, S. and Garcia-Bellido, A. (1997). Developmental parameters of cell death in the wing disc of Drosophila. Proc. Natl. Acad. Sci. USA 94, 5691-5696.
26. Moore, S. M. and Chang, Y. (2003). Kaposi's sarcoma associated herpervirus immunoevasion and tumorogenesis Annu. Rev. Microbiol. 57, 609-639.
27. Morata, G. and Lawrence, P. A. (1975). Control of compartment development by the engrailed gene in Drosophila. Nature 265, 614-617.
28. Moreno, E., Basler, K. and Morata, G. (2002). Cells compete for the Decapentaplegic survival factor to prevent apoptosis in Drosophila wing development. Nature 416, 755-759.
29. Neumann, C. J. and Cohen, S. M. (1996). Distinct mitogenic and cell fate specification functions of wingless in different regions of the wing. Development 122, 1781-1789.
30. Ollmann, M., Young, L. M., Di Como, C. J., Karim, F., Belvin, M., Robertson, S., Whittaker, K., Demsky, M., Fisher, W. W., Buchman, A. et al. (2000). Drosophila p53 is a structural and functional homolog of the tumor suppressor p53. Cell 101, 91-101.
31. Richardson, H. and Kumar, S. (2002). Death to flies: Drosophila as a model system to study programmed cell death. J. Immunol. Methods 265, 21-38.
32. Ryoo, H. D., Bergman, A., Gonen, H., Ciechanover, A. and Steller, H. (2002). Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1. Nat. Cell Biol. 4, 432-438.
33. Ryoo, H. D., Gorenc, T. and Steller, H. (2004). Apoptotic cells can induce compensatory cell proliferation through the JNK and the wingless signaling pathways. Dev. Cell. 7, 491-501.
34. Taipale, J. and Beachy, P. A. (2001). The Hedgehog and Wnt signalling pathways in cancer. Nature 411, 349-354.
35. Vaux, D. L. and Korsmeyer, S. J. (1999). Cell death in development. Cell 96, 245-254.
36. Wang, S. L., Hawkins, C. J., Yoo, S. J., Muller, H. A. and Hay, B. A. (1999). The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID. Cell 98, 453-463.
37. White, K. and Steller, H. (1995). The control of apoptosis in Drosophila. Trends Cell Biol. 5, 74-78.
38. White, K., Grether, M. E., Abrams, J. M., Young, L., Farrell, K. and Steller, H. (1994). Genetic control of programmed cell death in Drosophila. Science 264, 677-683.
39. Wolff, T. and Ready, D. F. (1991). Cell death in normal and rough eye mutants of Drosophila. Development 113, 825-839.
40. Yoo, S. J., Huh, J. R., Muro, I., Yu, H., Wang, L., Wang, S. L., Feldman, R. M., Clem, R. J., Muller, H. A. and Hay, B. A. (2002). Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms. Nat. Cell Biol. 4, 416-424.
41. Yu, S. Y., Yoo, S. J., Yang, L., Zapata, C., Srinivasan, A., Hay, B. A. and Baker, N. E. (2002). A pathway of signals regulating effector and initiator caspases in the developing Drosophila eye. Development 129, 3269-3278.