A small domain of CBP/p300 binds diverse proteins: Solution structure and functional studies

Molecular Cell

Volumn 8, Issue 3, 2001, Pages 581-590

  Lin, Charles H ^a,b   Hare, Brian J ^c   Wagner, Gerhard ^c   Harrison, Stephen C ^a,c   Maniatis, Tom ^a   Fraenkel, Ernest ^a  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD UNIVERSITY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; INTERFERON REGULATORY FACTOR 3; PROTEIN CBP; PROTEIN P300; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NUCLEAR MAGNETIC RESONANCE; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS;

EID: 0034785837     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(01)00333-1     Document Type: Article

References (59)

1. Inhibition of the cellular response to interferons by products of the adenovirus type 5 E1A oncogene
2. An alternative 3D NMR technique for correlating backbone N-15 with side chain Hβ resonances in larger proteins
3. Characterization of the transcriptional regulator YY1
4. The program XEASY for computer-supported NMR spectral-analysis of biological macromolecules
5. Gene activation by histone and factor acetyltransferases
6. Plant orthologs of p300/CBP: Conservation of a core domain in metazoan p300/CBP acetyltransferase-related proteins
7. Crystallography & NMR system: A new software suite for macromolecular structure determination
8. A flexible motif search technique based on generalized profiles
9. Functional analysis of human herpesvirus 8-encoded viral interferon regulatory factor 1 and its association with cellular interferon regulatory factors and p300
10. 13C-separated rotating frame Overhauser spectroscopy
11. Protein backbone angle restraints from searching a database for chemical shift and sequence homology
12. Solution structure of the TAZ2 (CH3) domain of the transcriptional adaptor protein CBP
13. An interactive graphic program for calculating the secondary structure content of proteins from circular dichroism spectrum
14. A fully automatic evolutionary classification of protein folds: Dali Domain Dictionary version 3
15. Assembly of a functional beta interferon enhanceosome is dependent on ATF-2-c-jun heterodimer orientation
16. The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for Smad3 in TGF-β-induced transcriptional activation
17. Conjunction dysfunction: CBP/p300 in human disease
18. The coregulator exchange in transcriptional functions of nuclear receptors
19. CBP/p300 in cell growth, transformation, and development
20. Viral replication and the coactivators p300 and CBP
21. PROMOTIF - A program to identify and analyze structural motifs in proteins
22. Versatile molecular glue. Transcriptional control
23. TGF-β-stimulated cooperation of Smad proteins with the coactivators CBP/p300
24. p300/cAMP-responsive element-binding protein interactions with ets-1 and ets-2 in the transcriptional activation of the human stromelysin promoter
25. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
26. Regulated nuclear-cytoplasmic localization of interferon regulatory factor 3, a subunit of double-stranded RNA-activated factor 1
27. Differential use of CREB binding protein-coactivator complexes
28. Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain
29. AQUA and PROCHECK-NMR: Programs for checking the quality of protein structures solved by NNR
30. Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch
31. Inhibition of p300 histone acetyltransferase by viral interferon regulatory factor
32. Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation
33. Interferon regulatory factors: The next generation
34. Structure and function of the interferon-β enhanceosome
35. NMR structure of the 35-residue villin headpiece subdomain
36. Recruitment of CBP/p300 by the IFN-β enhanceosome is required for synergistic activation of transcription
37. Raster3D: Photorealistic molecular graphics
38. RNA helicase A mediates association of CBP with RNA polymerase II
39. The growing family of interferon regulatory factors
40. Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons
41. Ambiguous NOEs and automated NOE assignment
42. Phosphorylation of ETS transcription factor ER81 in a complex with its coactivators CREB-binding protein and p300
43. Virus infection leads to localized hyperacetylation of histones H3 and H4 at the IFN-β promoter
44. Analysis of an activator:coactivator complex reveals an essential role for secondary structure in transcriptional activation
45. Role of secondary structure in discrimination between constitutive and inducible activators
46. The E6 protein of human papillomavirus type 16 binds to and inhibits coactivation by CBP and p300
47. Factor-specific modulation of CREB-binding protein acetyltransferase activity
48. Solution structure of the KIX domain of CBP bound to the transactivation domain of CREB: A model for activator:coactivator interactions
49. Ets target genes: Past, present and future
50. Analysis of the steroid receptor coactivator 1 (SRC1)-CREB binding protein interaction interface and its importance for the function of SRC1
51. Nativelike structure and stability in a truncation mutant of a protein minidomain: The peripheral subunit-binding domain
52. 13C-labeling
53. Virus induction of human IFN-β gene expression requires the assembly of an enhanceosome
54. The transcriptional co-activator p/CIP binds CBP and mediates nuclear receptor function
55. Induced α helix in the VP16 activation domain upon binding to a human TAF
56. Binding of p53 to the KIX domain of CREB binding protein. A potential link to human T-cell leukemia virus, type I-associated leukemogenesis
57. The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways
58. Virus infection induces the assembly of coordinately activated transcription factors on the IFN-β enhancer in vivo
59. Crystal structures of c-Src reveal features of its autoinhibitory mechanism