The up-regulation of angiotensin II receptor type 1 and connective tissue growth factor are involved in high-glucose-induced fibronectin production by cultured human dermal fibroblasts

Journal of Dermatological Science

Volumn 47, Issue 2, 2007, Pages 127-139

  Yevdokimova, Natalia ^a   Podpryatov, Sergij ^b  

^a INSTITUTE OF HYDROBIOLOGY   (Ukraine)

^b Ministry of Health of Ukraine   (Ukraine)

Author keywords

Angiotensin II receptor type 1; Connective tissue growth factor; Dermal fibroblasts; Fibronectin; High glucose

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; CONNECTIVE TISSUE GROWTH FACTOR; FIBRONECTIN; GLUCOSE; LOSARTAN; MESSENGER RNA; NEUTRALIZING ANTIBODY; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ADULT; CELL COUNT; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; DERMIS; FEMALE; FIBROBLASTS; FIBRONECTINS; FIBROSIS; GENE EXPRESSION; GLUCOSE; HUMANS; IMMEDIATE-EARLY PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; RECEPTOR, ANGIOTENSIN, TYPE 1; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 34249934514     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2007.02.009     Document Type: Article

References (50)

1. Huntley A.C. Cutaneous manifestations of diabetes mellitus. Dermatol Clin 7 (1989) 531-546
2. Sternberg M., Cohen-Forterre L., and Peyroux J. Connective tissue in diabetes mellitus: biochemical alterations of the intercellular matrix with special references to proteoglycans, collagens and basement membranes. Diabetes Metabol 11 (1985) 27-50
3. Blobe G.C., Schiemann W.P., and Lodish H.F. Role of transforming growth factor beta in human disease. N Engl J Med 342 (2000) 1350-1358
4. Jude E.B., Blakytny R., Bulmer J., Boulton A.J., and Ferguson M.W. Transforming growth factor-beta 1,2,3 and receptor type I and II in diabetic foot ulcers. Diabetes Med 19 (2002) 440-447
5. Twigg S.M., Chen M.M., Joly A.H., Chakrapani S.D., Tsubaki J., Kim H.-S., et al. Advanced glycosylation end products up-regulate connective tissue growth factor (insulin-like growth factor-binding protein-related protein 2) in human fibroblasts: a potential mechanism for expansion of extracellular matrix in diabetes mellitus. Endocrinology 142 (2001) 1760-1769
6. Twigg S.M., Joly H., Chen M.M., Tsubaki J., Kim H.-S., Hwa V., et al. Connective tissue growth factor/IGF-binding protein-related protein 2 is a mediator in the induction of fibronectin by advanced glycosylation end-products in human dermal fibroblasts. Endocrinology 143 (2002) 1260-1269
7. Yevdokimova N. High glucose-induced alterations of extracellular matrix of human skin fibroblasts are not dependent on TSP-1-TGFβ1 pathway. J Diab Complic 17 (2003) 355-364
8. Lee C.I., Guh J.Y., Chen H.C., Lin K.H., Yang Y.L., Hung W.C., et al. Leptin and connective tissue growth factor in advanced glycation end-product-induced effects in NRK-49F cells. J Cell Biochem 93 (2004) 940-950
9. Lee C.I., Guh J.Y., Chen H.C., Hung W.C., Yang Y.L., and Chuang L.Y. Advanced glycation end-product-induced mitogenesis and collagen production are dependent on angiotensin II and connective tissue growth factor in NRK-49F cells. J Cell Biochem 95 (2005) 281-292
10. Zhou G., Li C., and Cai L. Advanced glycation end-products induce connective tissue growth factor - mediated renal fibrosis predominantly through transforming growth factor beta - independent pathway. Am J Pathol 165 6 (2004) 2033-2043
11. Lam S., van der Gest R.N., Verhagen N.A.M., van Nieuwenhoven F.A., Blom I.E., Aten J., et al. Connective tissue growth factor and IGF-1 are produced by human renal fibroblasts and cooperate in the induction of collagen production by high glucose. Diabetes 52 (2003) 2975-2983
12. Blom I.E., Goldschmeding R., and Leask A. Gene regulation of connective growth factor: new targets for antifibrotic therapy?. Matrix Biol 21 (2002) 473-482
13. Iwanciw D., Rehm M., Porst M., and Goppelt-Struebe M. Induction of connective growth factor by angiotensin. II. Integration of signaling pathways. Arterioscler Thromb Vasc Biol 23 (2003) 1782-1785
14. Rupérez M., Lorenzo O., Blanco-Colio L.M., Esteban V., Egido J., and Ruiz-Ortega M. Connective tissue growth factor is a mediator of angiotensin II-induced fibrosis. Circulation 108 (2003) 1499-1505
15. Rodriguez-Vita J., Sánchez-López E., Esteban V., Rupérez M., Egido J., and Ruiz-Ortega M. Angiotensin II activates the Smad pathway in vascular smooth muscle cells by a transforming growth factor-β-independent mechanism. Circulation 111 (2005) 2509-2517
16. Finckenberg P., Inkinen K.M., Ahonen J., et al. Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways. Am J Pathol 163 (2003) 355-366
17. Ahmed M.S., Øie E., Vinge L.E., Yndestad A., Andersen G.Ø., Andersson Y., et al. Connective tissue growth factor-a novel mediator of angiotensin II-stimulated cardiac fibroblasts activation in heart failure in rats. J Mol Cell Cardiol 36 (2004) 393-404
18. Yu J., Prado G.N., Taylor L., Piserchio A., Gupta A., Mierke D.F., et al. Global chimeric exchanges within the intracellular face of the bradykinin B2 receptor with corresponding angiotensin II type 1a receptor regions: generation of fully functional hybrids showing characteristic signaling of the AT1a receptor. J Cell Biochem 85 (2002) 809-819
19. Asbun J., Manso A.M., and Villarreal F.J. Profibrotic influence of high glucose concentration on cardiac fibroblast functions: effects of lorsatan and vitamin E. Am J Physiol Heart Circ Physiol 288 (2005) H227-H234
20. Sodhi C.P., Kanwar Y.S., and Sahai A. Hypoxia and high glucose upregulate AT1 receptor expression and potentiate ANG II-induced proliferation in VSM cells. Am J Physiol Heart Circ Physiol 284 (2003) H846-H852
21. Privratsky J.R., Wold L.E., Sowers J.R., Quinn M., and Ren J. AT1 blockade prevents glucose-induced cardiac dysfunction in ventricular myocytes. Role of the AT1 receptor and NADPH oxidase. Hypertension 42 (2003) 206-212
22. Fiordaliso F., Leri A., Cesselli D., Limana F., Safai B., Nadal-Ginard B., et al. Hyperglycemia activates p53 and p53-regulated genes leading to myocyte cell death. Diabetes 50 (2001) 2363-2375
23. Becker B.N., Kondo S., Cheng H.F., and Harris R.C. Effect of glucose, pyruvate, and insulin on type 1 angiotensin II receptor expression in SV-immortalized rabbit proximal tubule epithelial cells. Kidney Int 52 (1997) 87-92
24. Kim S., and Iwao H. Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal diseases. Pharmacol Rev 52 (2000) 11-34
25. Smallridge R.C., Gamblin G.T., and Eil C. Angiotensin-converting enzyme: characteristics in human skin fibroblasts. Metabolism 35 (1986) 899-904
26. Nickening G., Geisen G., Vetter H., and Sachindis A. Characterization of angiotensin receptors on human skin fibroblasts. J Mol Med 75 (1997) 217-222
27. Steckelings U.M., Wollschläger T., Peters J., Henz B.M., Hermes B., and Artuc M. Human skin: source of and target organ for angiotensin II. Exp Dermatol 13 (2004) 148-154
28. Galindo M., Santiago B., Palao G., Gutierrez-Cañas I., Ramirez J.C., and Pablos J.L. Coexpression of AT1 and AT2 receptors by human fibroblasts is associated with resistance to angiotensin II. Peptides 26 (2005) 1647-1653
29. Yahata Y., Shirakata Y., Tokumaru S., et al. A novel function of angiotensin II in skin wound healing: induction of fibroblast and keratinocyte migration by angiotensin II via HB-EGF-mediated EGF receptor transactivation. J Biol Chem 281 (2006) 13209-13216
30. Yevdokimova NYu, and Podpryatov S.E. Hyaluronic acid production and CD44 expression in cultured dermal fibroblasts of patients with non-insulin-dependent diabetes mellitus with and without chronic ulcers on the lower extremity. Wound Repair Regen 13 (2005) 181-188
31. Skehan P., Storeng R., Scudiero D., et al. New colorimetric cytotoxicity assay for anticancer drug screening. J Natl Cancer Inst 82 (1990) 1107-1112
32. Taplin M.E., and Balk S.P. Androgen receptor: a key molecule in the progression of prostate cancer to hormone independence. J Cell Biochem 91 (2004) 483-490
33. Li D., Yang B., Philips M.I., and Mehta J.L. Proapoptotic effects of ANG II in human coronary artery endothelial cells: role of AT1 receptor and PKC activation. Am J Physiol 276 (1999) H786-H792 [Heart Circ Physiol 45]
34. Morrisey K., Evans R.A., Wakefield L., and Phillips A.O. Translational regulation of renal proximal tubular epithelial cell transforming growth factor-β1 generation by insulin. Am J Pathol 159 (2001) 1905-1915
35. Wahab N.A., Yevdokimova N., Weston B.S., Roberts T., Li X.J., Brinkman H., et al. Role of connective tissue growth factor in the pathogenesis of diabetic nephropathy. Biochem J 359 (2001) 77-87
36. Vidotti D.B., Casarini D.E., Cristovam P.C., Leite C.A., Schor N., and Boim M.A. High glucose concentration stimulates intracellular renin activity and angiotensin II generation in rat mesangial cells. Am J Physiol Renal Physiol 286 (2004) F1039-F1045
37. Singh R., Singh A.K., Alavi N., and Leehey D.J. Mechanism of increased angiotensin II levels in glomerular mesangial cells cultured in high glucose. J Am Soc Nephrol 14 (2003) 873-880
38. Amiri F., and Garcia R. Regulation of angiotensin II receptors and PKC isoforms by glucose in rat mesangial cells. Am J Physiol 276 (1999) F691-F699 [Renal Physiol 45]
39. Chouinard R.E., Meek R.L., Cooney S.K., and Tuttle K.R. Effects of amino acids and glucose on mesangial cell aminopeptidase A and angiotensin receptors. Kidney Int 61 (2002) S106-S109
40. Kagami S., Border W.A., Miller D.E., and Noble N.A. Angiotensin II stimulates extracellular matrix protein synthesis through induction of TGFbeta1 expression in rat mesangial cells. J Clin Invest 93 (1994) 2431-2437
41. Naito T., Masaki T., Nikolic-Peterson D.J., Tanji C., Yorioka N., and Kohno N. Angiotensin II induces thrombospondin-1 production in human mesangial cells via p53MAPK and JNK: a mechanism for activation of latent TGFbeta1. J Physiol Renal Physiol 286 (2003) F278-F287
42. Zhou Y., Poczatek M.H., Berecek K.H., and Murphy-Ullrich J.E. Thrombospondin 1 mediates angiotensin II induction of TGF-beta activation by cardiac and renal cells under both high and low glucose conditions. Biochem Biophys Res Commun 339 (2006) 633-641
43. Benazzoug Y., Borchiellini C., Labat-Robert J., Robert L., and Kern P. Effect of high-glucose concentrations on the expression of collagens and fibronectin by fibroblasts in culture. Exp Gerontol 33 (1998) 445-455
44. Phan-Thanh L., Robert L., Derouette J.C., and Labat-Robert J. Increased biosynthesis and processing of fibronectin in fibroblasts from diabetic mice. Proc Natl Acad Sci USA 4 (1987) 1911-1915
45. Frazier K., Williams S., Kothapalili D., Klapper H., and Grotendorst G.R. Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor. J Invest Dermatol 107 (1996) 404-411
46. Mimura Y., Ihn H., Jinnin M., Asano Y., Yamane K., and Tamaki K. Epidermal growth factor induces fibronectin expression in human dermal fibroblasts via protein kinase C delta signaling pathway. J Invest Dermatol 122 (2004) 1390-1398
47. Fischer T.A., Ungureanu-Longrois D., Singh K.M., et al. Regulation of bFGF expression and ANG II secretion in cardiac myocytes and microvascular endothelial cells. Am J Physiol 272 2 Pt2 (1997) H958-H968
48. Ogata S., Yorioka N., and Kohno N. Glucose prednisolone alter basic fibroblast growth factor expression in peritoneal mesothelial cells and fibroblasts. J Am Soc Nephrol 12 (2001) 2787-2796
49. Li D., Saldeen T., Romeo F., and Mehta J.L. Oxidized LDL upregulates angiotensin II type 1 receptor expression in cultured human coronary artery endothelial cells. The potential role of transcription factor NF-κB. Circulation 102 (2000) 1970-1976
50. Villacorta L., Graça-Souza A.V., Ricciarelli R., Zingg J.-M., and Azzi A. α-Tocopherol induces expression of connective tissue growth factor and antagonizes tumor necrosis factor-α-mediated downregulation in human smooth muscle cells. Circ Res 92 (2003) 104-110