Characterization of angiotensin receptors on human skin fibroblasts

Journal of Molecular Medicine

Volumn 75, Issue 3, 1997, Pages 217-222

  Nickenig, Georg ^a,b   Geisen, Gabriele ^a   Vetter, Hans ^a   Sachinidis, Agapios ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Angiotensin II; Arteriosclerosis; Human skin fibroblasts; Hypertension

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; 2 BUTYL 4 CHLORO 1 [[2' (1H TETRAZOL 5 YL) 4 BIPHENYLYL]METHYL] 5 IMIDAZOLECARBOXYLIC ACID; ANGIOTENSIN; ANGIOTENSIN RECEPTOR; ANGIOTENSIN RECEPTOR ANTAGONIST; CANDESARTAN HEXETIL; LOSARTAN POTASSIUM; MESSENGER RNA;

ANGIOGENESIS; ARTICLE; BLOOD PRESSURE; CALCIUM METABOLISM; CELL GROWTH; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; RECEPTOR BINDING;

ANGIOTENSIN II; BINDING, COMPETITIVE; CALCIUM; CELL DIVISION; CELLS, CULTURED; FIBROBLASTS; HUMANS; NUCLEIC ACID HYBRIDIZATION; RECEPTORS, ANGIOTENSIN; RNA, MESSENGER; SIGNAL TRANSDUCTION; SKIN;

EID: 0030938974     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001090050106     Document Type: Article

References (33)

1. Caponi AM, Aguilera G, Fakunding JL, Catt KJ (1981) Angiotensin II: receptors and mechanisms of action. In: RL Softer (ed) Biochemical regulation of blood pressure. Wiley, New York, pp 205-262
2. Peach MJ (1977) Renin-angiotensin system: biochemistry and mechanism of action. Physiol Rev 57:313-370
3. Daemen MJAP, Lombardi DM, Bosman FT, Schwartz SM (1991) Angiotensin II induces smooth muscle cell proliferation in the normal and injured rat arterial wall. Circ Res 68:450-456
4. Morgan HE, Baker KM (1991) Cardiac hypertrophy: mechanical, neural and endocrine dependence. Circulation 83:13-25
5. Sachinidis A, Ko Y, Nettekoven W, Wieczorek AJ, Düsing R, Vetter H (1992) The effect of angiotensin II on DNA synthesis varies considerably in vascular smooth muscle cells from different Wistar-Kyoto rats. J Hypertens 10:1159-1164
6. Sadoshima J, Izumo S (1993) Molecular characterization of angiotensin II-induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts: critical role of the AT1 receptor subtype. Circ Res 73:413-423
7. Crabos M, Roth M, Hahn AWA, Erne P (1994) Characterization of angiotensin II receptors in cultured adult rat cardiac fibroblasts. J Clin Invest 93:2372-2378
8. Le Noble FAC, Schreurs NHJS, van Straaten HWM, Slaaf DW, Smits JFM, Rogg H, Struijker-Boudier HAJ (1993) Evidence for a novel angiotensin II receptor involved in angiogenesis in chick chorioallantoic membrane. Am J Physiol 264:R460-465
9. Fernandez LA, Twickler J, Mead A (1985) Neovascularization produced by angiotensin II. J Lab Clin Med 105, 141-145
10. Ahmed A, Xiao FL, Shams M, Gregory J, Rollason T, Barnes NM, Newton JR (1995) Localization of the angiotensin II and its receptor subtype expression in human endometrium and identification of a novel high-affinity angiotensin II. J Clin Invest 96:848-857
11. Griendling KK, Lassegue B, Murphy TJ, Alexander RW (1994) Angiotensin II receptor pharmacology. Adv Pharma 28:269-306
12. Sun Y, Diaz-Arias AA, Weber KT (1994) Angiotensin-converting enzyme, bradykinin, and angiotensin II receptor binding in rat skin, tendon, and heart valves: an in vitro, quantitative autoradiographic study. J Lab Clin Med 123:372-377
13. Matsubara H, Kanasaki M, Murasawa S, Tsukaguchi Y, Nio Y, Inada M (1994) Differential gene expression and regulation of angiotensin II receptor subtypes in rat cardiac fibroblasts and cardiomyocytes in culture. J Clin Invest 93:1592-1601
14. Neuß M, Regitz-Zagrosek V, Hildebrandt A, Fleck E (1994) Human cardiac fibroblasts express an angiotensin receptor with unusual binding characteristics which is coupled to cellular proliferation. Biochem Biophys Res Commun 204:1334-1339
15. Berrettini WH, Nadi NS, Gershon ES (1983) Absence of specific binding of several putative neuro-transmitters to human fibroblasts. J Recep Res 3:409-421
16. Bradford M (1976) A rapid and sensitive method of the quantification of microgramm quantities of protein utilizing the principal protein-dye binding. Anal Biochem 65:42-49
17. Murphy TJ, Alexander RW, Griendling KK, Runge MS, Bernstein KE (1991) Isolation of a cDNA encoding the vascular type-1 angiotensin II receptor. Nature 351:233-236
18. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-34350
19. Takeuchi K, Alexander RW, Nakamura Y, Tsujino T, Murphy TJ (1993) Molecular structure and transcriptional function of the rat vascular AT1a angiotensin receptor gene. Circ Res 73:612-621
20. Timmermans PBMWM, Wong PC, Chin AZ, Herblin WH, Benfield P, Carini DJ, Lee RJ, Wexler RR, Saye JAM, Smith R (1993) Angiotensin II receptors and angiotensin II receptor antagonists. Pharm Rev 45:206-251
21. Mukoyama M, Nakajima M, Horiuchi M, Sasamura H, Pratt RE, Dzau VJ (1993) Expression cloning of type 2 angiotensin II receptor reveals a unique class of seven-transmembrane receptors. J Biol Chem 268:24539-24542
22. Kambayashi Y, Bardhan S, Takahashi K, Tsuzuki S, Inui H, Hamakubo T, Inagaini T (1993) Molecular cloning of a novel angiotensin II receptor isoform involved in phosphotyrosine phosphatase inhibition. J Biol Chem 268:24543-24546
23. Bottari SP, deGasparo M, Stevkelings UM, Levens NR (1993) Angiotensin II receptor subtypes: characterization, signalling mechanism, and possible physiological implications. Frontiers Neuroendocrinol 2:123-171
24. Lassegue B, Alexander RW, Nickenig G, Clark M, Murphy TJ, Griendling KK (1995) Angiotensin II down-regulates the vascular smooth muscle AT1 receptor by transcriptional and post-transcriptional mechanisms: evidence for homologous and heterologous regulation. Mol Pharm 48:601-609
25. Nickenig G, Murphy TJ (1994) Down-regulation by growth factors of vascular smooth muscle angiotensin receptor gene expression. Mol Pharm 46:653-659
26. Schiavone MT, Santos RA, Brosnihan KB, Khosla MC, Ferrario CM (1988) Release of vasopressin from the rat hypothalamo-neurohypophysical system by angiotensin (1-7) heptapepteide. Proc Soc Natl Acad Sci USA 85:4095-4098
27. Campagnole-Santos MJ, Diz DI, Ferrario CM (1990) Actions of angiotensin peptides after partial denervation of the solitary tract nucleus. Hypertension 15[Suppl 2]: 134-139
28. Jaiswal N, Diz DI, Tallant A, Khosla MC, Ferreario CM (1991) Characterization of angiotensin receptors mediating prostaglandin synthesis in C6 glioma cells. Am J Physiol 260:R1000-R1006
29. Porsti I, Bara AT, Busse R, Hecker M (1994) Release of nitric oxide by angiotensin (1-7) from porcine coronary endothelium: implications for a novel angiotensin receptor. Br J Pharamacol 111 (3):652-654
30. Santos RAS, Campagnole-Santos MJ (1994) Central and peripheral actions of angiotensin- (1-7). Braz J Med Biol Res 27:1033-1047
31. Gyurko R, Kimura B, Kurian P, Crews FT, Phillips MI (1992) Angiotensin II receptor subtypes play opposite roles in regulating phosphatidylinositol hydrolysis in rat skin sclices. Biophys Biochem Res Commun 186:285-292
32. Kimura A, Sumners C, Phillips MI (1992) Changes in skin angiotensin II receptors in rats during wound healing. Biophys Biochem Res Commun 187:1083-1090
33. Freeman EJ, Chisolm GC, Ferrario CM, Tallant EA (1996) Angiotensin- (1-7) inhibits vascular smooth muscle cell growth. Hypertension 28:104-108