Mechanism of increased angiotensin II levels in glomerular mesangial cells cultured in high glucose

Journal of the American Society of Nephrology

Volumn 14, Issue 4, 2003, Pages 873-880

  Singh, Rekha ^a,b   Singh, Ashok K ^c   Alavi, Nahid ^d   Leehey, David J ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

^c Hektoen Institute for Medical Research   (United States)

^d JESSE BROWN VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; LOSARTAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRUSH BORDER; CELL COMPARTMENTALIZATION; CELL CULTURE; CONTROLLED STUDY; DNA LIBRARY; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; GLOMERULOSCLEROSIS; GLUCOSE METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MESANGIUM CELL; NONHUMAN; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

EID: 0037378932     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ASN.0000060804.40201.6E     Document Type: Article

References (23)

1. Zatz R, Dunn BR, Meyer TW, Anderson S, Rennke HG, Brenner BM: Prevention of diabetic glomerulopathy by pharmacological amelioration of glomerular capillary hypertension. J Clin Invest 77: 1925-1930, 1986
2. Remuzzi A, Fassi A, Sangalli F, Malanchini B, Mohamed EI, Bertani T, Remuzzi G: Prevention of renal injury in diabetic MWF rats by angiotensin II antagonism. Exp Nephrol 6: 28-38, 1998
3. Lewis EJ, Hunsicker LG, Bain RP, Rohde RD: The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. N Engl J Med 329: 1456-1462, 1993
4. Ayo SH, Radnik RK, Glass II WF, Garoni J, Rampt ER, Appling DR, Kreisberg JI: Increased extracellular matrix synthesis and mRNA in mesangial cells grown in high-glucose medium. Am J Physiol 260: F185-F191, 1991
5. Danne T, Spiro MJ, Spiro RG: Effect of high glucose on type IV collagen production by cultured glomerular epithelial, endothelial and mesangial cells. Diabetes 42: 170-177, 1993
6. Ray PE, Bruggeman LA, Horikoshi A, Auilera G, Klotman PE: Angiotensin II stimulates human fetal mesangial cell proliferation and fibronectin biosynthesis by binding to AT 1 receptors. Kidney Int 45: 177-184, 1994
7. Singh R, Alavi N, Singh AK, Leehey DJ: Role of angiotensin II in glucose-induced inhibition of mesangial matrix degradation. Diabetes 48: 2066-2073, 1999
8. Price DA, Porter LE, Gordon M, Fisher ND, De'Oliveira JM, Laffel LM, Passan DR, Williams GH, Hollenberg NK: The paradox of the low-renin state in diabetic nephropathy. J Am Soc Nephrol 10: 2382-2391, 1999
9. Seikaly MG, Arant BS Jr, Seney FD Jr: Endogenous angiotensin concentrations in specific intrarenal fluid compartments in the rat. J Clin Invest 86: 1352-1357, 1990
10. Ballerman BJ, Skorecki KL, Brenner BM: Reduced glomerular angiotensin II receptor density in early untreated diabetes mellitus in the rat. Am J Physiol 247: F110-F116, 1984
11. Zhang SL, To C Chen X, Filep JG, Tang SS, Ingelfinger JR, Carriere S, Chan JS: Effect of renin-angiotensin system blockade on the expression of the angiotensinogen gene and induction of hypertrophy in rat kidney proximal tubular cells. Exp Nephrol 9: 109-117, 2001
12. Zhang SL, Tang SS, Chen X, Filep JG, Inglefinger JR, Chan JSD: High levels of glucose stimulate angiotensinogen gene expression via the p38 mitogen-activated protein kinase pathway in rat kidney proximal tubular cells. Endocrinology 141: 4637-4646, 2000
13. Becker BN, Yasuda T, Kondo S, Vaikunth S, Homma T, Harris RC: Mechanical stretch/relaxation stimulates a cellular renin-angiotensin system in cultured rat mesangial cells. Exp Nephrol 6: 57-66, 1998
14. Andrade MCC, Quinto BM, Carmona AK, Ribas OS, Boim MA, Schor N, Casarini DE: Purification and characterization of angiotensin I-converting enzymes from mesangial cells in culture. J Hypertension 16: 2063-2074, 1998
15. Singh R, Song RH, Alavi N, Pegoraro AA, Singh AK, Leehey DJ: High glucose decreases matrix metalloproteinase-2 activity in rat mesangial cells via transforming growth factor-β1. Exp Nephrol 9: 249-257, 2001
16. Carmel A, Rogozinsky SH, Yaron A: A fluorimetric assay for angiotensin-converting enzyme in human serum. Clinica Chimica Acta 93: 215-220, 1979
17. Sibnoy M, Gasc JM, Soubrier F, Alhenc-Gelas F, Corvol P: Gene expression and tissue localization of the two isoforms of angiotensin I-converting enzyme. Hypertension 21: 827-835, 1993
18. Ruiz-Ortega M, Gonzalez S, Daniel S, Condom E, Bustos C, Largo R, Gonzalez E, Ortiz A, Egido J: ACE inhibition reduces proteinuria, glomerular lesions and extracellular matrix production in a normotensive rat model of immune complex nephritis. Kidney Int 48: 1778-1791, 1995
19. Casarini DE, Boim MA, Stella RCR, Krieger-Azzolini MH, Krieger JE, Schor N: Angiotensin I-converting enzyme activity in tubular fluid along the rat nephron. Am J Physiol 272: F405-F409, 1997
20. Changaris DG, Miller JJ, Levy RS: Angiotensin II generated by a human renal carboxypeptidase. Biochem Biophys Res Commun 31: 573-579, 1986
21. Donoghue M, Hsieh F, Baronas E, Godbout K, Gosselin M, Stagliano N, Donovan M, Woolf B, Robbbbison K, Jeyaseelan R, Breitbart RE, Acton S: A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ Res 87: e1-e9, 2000
22. Tipnis SA, Hooper NM, Hyde R, Karran E, Christie G, Turner AJ: A human homolog of angiotensin-converting enzyme. J Biol Chem 275: 33238-33243, 2000
23. Leehey DJ, Singh AK, Alavi N, Singh R: Role of angiotensin II in diabetic nephropathy. Kidney Int Suppl 77: S93-S98, 2000