Concomitant loss of proapoptotic BH3-only Bcl-2 antagonists Bik and Bim arrests spermatogenesis

EMBO Journal

Volumn 24, Issue 22, 2005, Pages 3963-3973

  Coultas, Leigh ^a,e   Bouillet, Philippe ^a   Loveland, Kate L ^b   Meachem, Sarah ^c   Perlman, Harris ^d   Adams, Jerry M ^a   Strasser, Andreas ^a  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c MONASH MEDICAL CENTRE   (Australia)

^d SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

Author keywords

Apoptosis; BH3 only protein; Bik; Bim; Spermatogenesis

Indexed keywords

BH3 PROTEIN; BIK PROTEIN; BIM PROTEIN; PROTEIN; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GERM CELL; INFERTILITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SERTOLI CELL; SPERMATOCYTE; SPERMATOGENESIS; SPERMATOGONIUM; SPERMATOZOON; STATISTICAL SIGNIFICANCE; TESTIS; TESTIS DEVELOPMENT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; FERTILITY; GERM CELLS; HEMATOPOIETIC STEM CELLS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIAL PROTEINS; ORGAN SIZE; PHENOTYPE; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-KIT; SPERMATOGENESIS; SPERMATOZOA; TESTIS;

ANIMALIA;

EID: 27844539294     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600857     Document Type: Article

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