-
1
-
-
0028880455
-
Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor
-
Wu H., Liu X., Jaenisch R., Lodish H.F. Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor. Cell. 83:1995;59-67.
-
(1995)
Cell
, vol.83
, pp. 59-67
-
-
Wu, H.1
Liu, X.2
Jaenisch, R.3
Lodish, H.F.4
-
2
-
-
0027215519
-
Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis
-
de la Chapelle A., Traskelin A-L., Juvonen E. Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis. Proc. Natl. Acad. Sci. U. S. A. 90:1993;4495-4499.
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 4495-4499
-
-
De La Chapelle, A.1
Traskelin, A.-L.2
Juvonen, E.3
-
3
-
-
0024563574
-
Expression cloning of the murine erythropoietin receptor
-
D'Andrea A.D., Lodish H.F., Wong G.G. Expression cloning of the murine erythropoietin receptor. Cell. 57:1989;277-285.
-
(1989)
Cell
, vol.57
, pp. 277-285
-
-
D'Andrea, A.D.1
Lodish, H.F.2
Wong, G.G.3
-
4
-
-
0029798402
-
Functional mimicry of a protein hormone by a peptide agonist: The EPO receptor complex at 2.8 Å
-
Livnah O.et al. Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 Å Science. 273:1996;464-471.
-
(1996)
Science
, vol.273
, pp. 464-471
-
-
Livnah, O.1
-
5
-
-
0026598960
-
Human growth hormone and extracellular domain of its receptor: Crystal structure of the complex
-
De Vos A.M., Ultsch M., Kossiakoff A.A. Human growth hormone and extracellular domain of its receptor: crystal structure of the complex. Science. 255:1992;306-311.
-
(1992)
Science
, vol.255
, pp. 306-311
-
-
De Vos, A.M.1
Ultsch, M.2
Kossiakoff, A.A.3
-
6
-
-
9444236174
-
Small peptides as potent mimetics of the protein hormone erythropoietin
-
Wrighton N.C.et al. Small peptides as potent mimetics of the protein hormone erythropoietin. Science. 273:1996;458-464.
-
(1996)
Science
, vol.273
, pp. 458-464
-
-
Wrighton, N.C.1
-
7
-
-
0028963213
-
Increased cell surface expression and enhanced folding in the endoplasmic reticulum of a mutant erythropoietin receptor
-
Hilton D.J., Watowich S.S., Murray P.J., Lodish H.F. Increased cell surface expression and enhanced folding in the endoplasmic reticulum of a mutant erythropoietin receptor. Proc. Natl. Acad. Sci. U. S. A. 92:1995;190-194.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 190-194
-
-
Hilton, D.J.1
Watowich, S.S.2
Murray, P.J.3
Lodish, H.F.4
-
8
-
-
0027400859
-
Inactivation of the erythropoietin receptor function by a point mutation in a region having homology with other cytokine receptors
-
Miura O., Cleveland J.L., Ihle J.N. Inactivation of the erythropoietin receptor function by a point mutation in a region having homology with other cytokine receptors. Mol. Cell. Biol. 13:1993;1788-1795.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 1788-1795
-
-
Miura, O.1
Cleveland, J.L.2
Ihle, J.N.3
-
9
-
-
0027327484
-
JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin
-
Witthuhn B.A.et al. JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin. Cell. 74:1993;227-236.
-
(1993)
Cell
, vol.74
, pp. 227-236
-
-
Witthuhn, B.A.1
-
10
-
-
0028979693
-
Interaction of the erythropoietin and stem-cell-factor receptors
-
Wu H., Klingmüller U., Besmer P., Lodish H.F. Interaction of the erythropoietin and stem-cell-factor receptors. Nature. 377:1995;242-246.
-
(1995)
Nature
, vol.377
, pp. 242-246
-
-
Wu, H.1
Klingmüller, U.2
Besmer, P.3
Lodish, H.F.4
-
11
-
-
0032006771
-
Signaling through the interaction of membrane-restricted stem cell factor and c-kit receptor tyrosine kinase: Genetic evidence for a differential role in erythropoiesis
-
Kapur R.et al. Signaling through the interaction of membrane-restricted stem cell factor and c-kit receptor tyrosine kinase: genetic evidence for a differential role in erythropoiesis. Blood. 91:1998;879-889.
-
(1998)
Blood
, vol.91
, pp. 879-889
-
-
Kapur, R.1
-
12
-
-
0032496370
-
Identification of a cytoplasmic motif in the erythropoietin receptor required for receptor internalization
-
Levin I.et al. Identification of a cytoplasmic motif in the erythropoietin receptor required for receptor internalization. FEBS Lett. 427:1998;164-170.
-
(1998)
FEBS Lett.
, vol.427
, pp. 164-170
-
-
Levin, I.1
-
13
-
-
0031045008
-
An alpha-helical signal in the cytosolic domain of the interleukin 2 receptor beta chain mediates sorting towards degradation after endocytosis
-
Subtil A., Delepierre M., Dautry-Varsat A. An alpha-helical signal in the cytosolic domain of the interleukin 2 receptor beta chain mediates sorting towards degradation after endocytosis. J. Cell. Biol. 136:1997;583-595.
-
(1997)
J. Cell. Biol.
, vol.136
, pp. 583-595
-
-
Subtil, A.1
Delepierre, M.2
Dautry-Varsat, A.3
-
14
-
-
0028332086
-
Activation and inhibition of erythropoietin receptor function: Role of receptor dimerization
-
Watowich S.S., Hilton D.J., Lodish H.F. Activation and inhibition of erythropoietin receptor function: role of receptor dimerization. Mol. Cell. Biol. 14:1994;3535-3549.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 3535-3549
-
-
Watowich, S.S.1
Hilton, D.J.2
Lodish, H.F.3
-
15
-
-
0029742943
-
Activation of the erythropoietin (EPO) receptor by bivalent anti-EPO receptor antibodies
-
Elliott S., Lorenzini T., Yanagihara D., Chang D., Elliott G. Activation of the erythropoietin (EPO) receptor by bivalent anti-EPO receptor antibodies. J. Biol. Chem. 271:1996;24691-24697.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 24691-24697
-
-
Elliott, S.1
Lorenzini, T.2
Yanagihara, D.3
Chang, D.4
Elliott, G.5
-
16
-
-
0025633003
-
Point mutation in the exoplasmic domain of the erythropoietin receptor resulting in hormone-independent activation and tumorigenicity
-
Yoshimura A., Longmore G., Lodish H.F. Point mutation in the exoplasmic domain of the erythropoietin receptor resulting in hormone-independent activation and tumorigenicity. Nature. 348:1990;647-649.
-
(1990)
Nature
, vol.348
, pp. 647-649
-
-
Yoshimura, A.1
Longmore, G.2
Lodish, H.F.3
-
17
-
-
0026326555
-
An activating mutation in the murine erythropoietin receptor induces erythroleukemia in mice: A cytokine receptor superfamily oncogene
-
Longmore G.D., Lodish H.F. An activating mutation in the murine erythropoietin receptor induces erythroleukemia in mice: a cytokine receptor superfamily oncogene. Cell. 67:1991;1089-1102.
-
(1991)
Cell
, vol.67
, pp. 1089-1102
-
-
Longmore, G.D.1
Lodish, H.F.2
-
19
-
-
0021929830
-
Malignant transformation of erythroid cells in vivo by introduction of a nonreplicating retrovirus vector
-
Wolff L., Ruscetti S. Malignant transformation of erythroid cells in vivo by introduction of a nonreplicating retrovirus vector. Science. 228:1985;1549-1552.
-
(1985)
Science
, vol.228
, pp. 1549-1552
-
-
Wolff, L.1
Ruscetti, S.2
-
20
-
-
0025004999
-
Activation of cell growth by binding of Friend spleen focus-forming virus gp55 glycoprotein to the erythropoietin receptor
-
Li J-P., D'Andrea A.D., Lodish H.F., Baltimore D. Activation of cell growth by binding of Friend spleen focus-forming virus gp55 glycoprotein to the erythropoietin receptor. Nature. 343:1990;762-764.
-
(1990)
Nature
, vol.343
, pp. 762-764
-
-
Li, J.-P.1
D'Andrea, A.D.2
Lodish, H.F.3
Baltimore, D.4
-
21
-
-
0024396858
-
Transmembrane domain of the envelope gene of a polycythemia-inducing retrovirus determines erythropoietin-independent growth
-
Chung S.W., Wolff L., Ruscetti S.K. Transmembrane domain of the envelope gene of a polycythemia-inducing retrovirus determines erythropoietin-independent growth. Proc. Natl. Acad. Sci. U. S. A. 86:1989;7957-7960.
-
(1989)
Proc. Natl. Acad. Sci. U. S. A.
, vol.86
, pp. 7957-7960
-
-
Chung, S.W.1
Wolff, L.2
Ruscetti, S.K.3
-
22
-
-
0032519769
-
The anemic Friend virus gp55 envelope protein induces erythroid differentiation in fetal liver colony-forming units-erythroid
-
Constantinescu S.N.et al. The anemic Friend virus gp55 envelope protein induces erythroid differentiation in fetal liver colony-forming units-erythroid. Blood. 91:1998;1163-1172.
-
(1998)
Blood
, vol.91
, pp. 1163-1172
-
-
Constantinescu, S.N.1
-
23
-
-
0026652875
-
The erythropoietin receptor transmembrane region is necessary for activation by the Friend spleen focus-forming virus gp55 glycoprotein
-
Zon L.I., Moreau J.F., Koo J.W., Mathey-Prevot B., D'Andrea A.D. The erythropoietin receptor transmembrane region is necessary for activation by the Friend spleen focus-forming virus gp55 glycoprotein. Mol. Cell. Biol. 12:1992;2949-2957.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 2949-2957
-
-
Zon, L.I.1
Moreau, J.F.2
Koo, J.W.3
Mathey-Prevot, B.4
D'Andrea, A.D.5
-
24
-
-
0030953469
-
Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop
-
Feng J.et al. Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop. Mol. Cell. Biol. 17:1997;2497-2501.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 2497-2501
-
-
Feng, J.1
-
25
-
-
18244432009
-
Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis
-
Neubauer H.et al. Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis. Cell. 93:1998;397-409.
-
(1998)
Cell
, vol.93
, pp. 397-409
-
-
Neubauer, H.1
-
26
-
-
0032076542
-
Jak2 is essential for signaling through a variety of cytokine receptors
-
Parganas E.et al. Jak2 is essential for signaling through a variety of cytokine receptors. Cell. 93:1998;385-395.
-
(1998)
Cell
, vol.93
, pp. 385-395
-
-
Parganas, E.1
-
27
-
-
0026502775
-
In vitro phosphorylation of the erythropoietin receptor and an associated protein, pp130
-
Yoshimura A., Lodish H.F. In vitro phosphorylation of the erythropoietin receptor and an associated protein, pp130. Mol. Cell. Biol. 12:1992;706-715.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 706-715
-
-
Yoshimura, A.1
Lodish, H.F.2
-
28
-
-
0030901234
-
Lyn tyrosine kinase is essential for erythropoietin-induced differentiation of J2E erythroid cells
-
Tilbrook P.A., Ingley E., Williams J.H., Hibbs M.L., Klinken S.P. Lyn tyrosine kinase is essential for erythropoietin-induced differentiation of J2E erythroid cells. EMBO J. 16:1997;1610-1619.
-
(1997)
EMBO J.
, vol.16
, pp. 1610-1619
-
-
Tilbrook, P.A.1
Ingley, E.2
Williams, J.H.3
Hibbs, M.L.4
Klinken, S.P.5
-
29
-
-
0032525115
-
Lyn physically associates with the erythropoietin receptor and may play a role in activation of the Stat5 pathway
-
Chin H.et al. Lyn physically associates with the erythropoietin receptor and may play a role in activation of the Stat5 pathway. Blood. 91:1998;3734-3745.
-
(1998)
Blood
, vol.91
, pp. 3734-3745
-
-
Chin, H.1
-
30
-
-
0028785893
-
Tyrosine 343 in the erythropoietin receptor positively regulates erythropoietin-induced cell proliferation and Stat5 activation
-
Damen J.E.et al. Tyrosine 343 in the erythropoietin receptor positively regulates erythropoietin-induced cell proliferation and Stat5 activation. EMBO J. 14:1995;5557-5568.
-
(1995)
EMBO J.
, vol.14
, pp. 5557-5568
-
-
Damen, J.E.1
-
31
-
-
0013077966
-
Identification of tyrosine residues within the intracellular domain of the erythropoietin receptor crucial for STAT5 activation
-
Gobert S.et al. Identification of tyrosine residues within the intracellular domain of the erythropoietin receptor crucial for STAT5 activation. EMBO J. 15:1996;2434-2441.
-
(1996)
EMBO J.
, vol.15
, pp. 2434-2441
-
-
Gobert, S.1
-
32
-
-
0029738317
-
Multiple tyrosine residues in the cytosolic domain of the erythropoietin receptor promote activation of STAT5.
-
Klingmüller U., Bergelson S., Hsiao J.G., Lodish H.F. Multiple tyrosine residues in the cytosolic domain of the erythropoietin receptor promote activation of STAT5. Proc. Natl. Acad. Sci. U. S. A. 93:1996;8324-8328.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 8324-8328
-
-
Klingmüller, U.1
Bergelson, S.2
Hsiao, J.G.3
Lodish, H.F.4
-
33
-
-
0000943469
-
Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses
-
Teglund S.et al. Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses. Cell. 93:1998;841-850.
-
(1998)
Cell
, vol.93
, pp. 841-850
-
-
Teglund, S.1
-
34
-
-
0028785505
-
Phosphorylation of tyrosine 503 in the erythropoietin receptor (EpR) is essential for binding the P85 subunit of phosphatidylinositol (PI) 3-kinase and for EpR-associated PI 3-kinase activity
-
Damen J.E., Cutler R.L., Jiao H., Yi T., Krystal G. Phosphorylation of tyrosine 503 in the erythropoietin receptor (EpR) is essential for binding the P85 subunit of phosphatidylinositol (PI) 3-kinase and for EpR-associated PI 3-kinase activity. J. Biol. Chem. 270:1995;23402-23408.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 23402-23408
-
-
Damen, J.E.1
Cutler, R.L.2
Jiao, H.3
Yi, T.4
Krystal, G.5
-
35
-
-
0030980933
-
Identification of a novel pathway important for proliferation and differentiation of primary erythroid progenitors
-
Klingmüller U.et al. Identification of a novel pathway important for proliferation and differentiation of primary erythroid progenitors. Proc. Natl. Acad. Sci. U. S. A. 94:1997;3016-3021.
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 3016-3021
-
-
Klingmüller, U.1
-
36
-
-
2642649497
-
Tyrosine residues within the intracellular domain of the erythropoietin receptor mediate activation of AP-1 transcription factors
-
Bergelson S., Klingmüller U., Socolovsky M., Hsiao J.G., Lodish H.F. Tyrosine residues within the intracellular domain of the erythropoietin receptor mediate activation of AP-1 transcription factors. J. Biol. Chem. 273:1998;2396-2401.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 2396-2401
-
-
Bergelson, S.1
Klingmüller, U.2
Socolovsky, M.3
Hsiao, J.G.4
Lodish, H.F.5
-
37
-
-
0031806003
-
AP1 regulation of proliferation and initiation of apoptosis in erythropoietin-dependent erythroid cells
-
Jacobs-Helber S.M., Wickrema A., Birrer M.J., Sawyer S.T. AP1 regulation of proliferation and initiation of apoptosis in erythropoietin-dependent erythroid cells. Mol. Cell. Biol. 18:1998;3699-3707.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3699-3707
-
-
Jacobs-Helber, S.M.1
Wickrema, A.2
Birrer, M.J.3
Sawyer, S.T.4
-
38
-
-
0030996142
-
The prolactin receptor and severely truncated erythropoietin receptors support differentiation of erythroid progenitors
-
Socolovsky M., Dusanter-Fourt I., Lodish H.F. The prolactin receptor and severely truncated erythropoietin receptors support differentiation of erythroid progenitors. J. Biol. Chem. 272:1997;14009-14012.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 14009-14012
-
-
Socolovsky, M.1
Dusanter-Fourt, I.2
Lodish, H.F.3
-
39
-
-
0032170077
-
-/- erythroid progenitors and replaces EpoR in a synergistic interaction with c-kit
-
-/- erythroid progenitors and replaces EpoR in a synergistic interaction with c-kit. Blood. 92:1998;1491-1496.
-
(1998)
Blood
, vol.92
, pp. 1491-1496
-
-
Socolovsky, M.1
Fallon, A.E.2
Lodish, H.F.3
-
40
-
-
0028956353
-
Specific recruitment of the hematopoietic protein tyrosine phosphatase SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals
-
Klingmüller K., Lorens U., Cantley L.C., Neel B.G., Lodish H.F. Specific recruitment of the hematopoietic protein tyrosine phosphatase SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals. Cell. 80:1995;729-738.
-
(1995)
Cell
, vol.80
, pp. 729-738
-
-
Klingmüller, K.1
Lorens, U.2
Cantley, L.C.3
Neel, B.G.4
Lodish, H.F.5
-
41
-
-
0028300494
-
Mutation in the negative regulatory element of the erythropoietin receptor gene in a case of sporadic primary polycythemia
-
Sokol L., Prchal J.F., D'Andrea A., Rado T.A., Prchal J.T. Mutation in the negative regulatory element of the erythropoietin receptor gene in a case of sporadic primary polycythemia. Exp. Hematol. 22:1994;447-453.
-
(1994)
Exp. Hematol.
, vol.22
, pp. 447-453
-
-
Sokol, L.1
Prchal, J.F.2
D'Andrea, A.3
Rado, T.A.4
Prchal, J.T.5
-
42
-
-
0029014206
-
A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors
-
Yoshimura A.et al. A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors. EMBO J. 14:1995;2816-2826.
-
(1995)
EMBO J.
, vol.14
, pp. 2816-2826
-
-
Yoshimura, A.1
-
43
-
-
0030839112
-
A new protein containing an SH2 domain that inhibits JAK kinases
-
Endo T.A.et al. A new protein containing an SH2 domain that inhibits JAK kinases. Nature. 387:1997;921-924.
-
(1997)
Nature
, vol.387
, pp. 921-924
-
-
Endo, T.A.1
-
44
-
-
2642684541
-
Targeted disruption of SHIP leads to hemopoitic perturbations, lung pathology, and a shortened life span
-
Helgason C.D.et al. Targeted disruption of SHIP leads to hemopoitic perturbations, lung pathology, and a shortened life span. Genes Dev. 12:1998;1610-1620.
-
(1998)
Genes Dev.
, vol.12
, pp. 1610-1620
-
-
Helgason, C.D.1
-
45
-
-
0345243401
-
Evidence for a selective-permissive role of cytokine receptors in hematopoietic cell fate decisions
-
(abstr.)
-
Stoffel R., Ledermann B., de Sauvage F.J., Skoda R.C. Evidence for a selective-permissive role of cytokine receptors in hematopoietic cell fate decisions. Blood. 90:1997;123 (abstr.).
-
(1997)
Blood
, vol.90
, pp. 123
-
-
Stoffel, R.1
Ledermann, B.2
De Sauvage, F.J.3
Skoda, R.C.4
-
46
-
-
0031587826
-
Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice
-
Akashi K., Kondo M., von Freeden-Jeffry U., Murray R., Weissman I.L. Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell. 89:1997;1033-1041.
-
(1997)
Cell
, vol.89
, pp. 1033-1041
-
-
Akashi, K.1
Kondo, M.2
Von Freeden-Jeffry, U.3
Murray, R.4
Weissman, I.L.5
-
47
-
-
0031587875
-
-/- mice
-
-/- mice. Cell. 89:1997;1011-1019.
-
(1997)
Cell
, vol.89
, pp. 1011-1019
-
-
Maraskovsky, E.1
-
48
-
-
0031052477
-
Functional interaction of erythropoietin and stem cell factor receptors is essential for erythroid colony formation
-
Wu H., Klingmüller U., Acurio A., Hsiao J.G., Lodish H.F. Functional interaction of erythropoietin and stem cell factor receptors is essential for erythroid colony formation. Proc. Natl. Acad. Sci. U. S. A. 94:1997;1806-1810.
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 1806-1810
-
-
Wu, H.1
Klingmüller, U.2
Acurio, A.3
Hsiao, J.G.4
Lodish, H.F.5
|