Inhibition of the CaaX proteases Rce1p and Ste24p by peptidyl (acyloxy)methyl ketones

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1773, Issue 6, 2007, Pages 853-862

  Porter, Stephen B ^a   Hildebrandt, Emily R ^a   Breevoort, Sarah R ^a   Mokry, David Z ^a   Dore, Timothy M ^a   Schmidt, Walter K ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

(acyloxy)methyl ketone; CaaX protein; Isoprenylation; Post translational modification; Protease; Ras

Indexed keywords

KETONE DERIVATIVE; PEPTIDYL(ACYLOXY)METHYL KETONE; PROTEIN; PROTEIN CAAX; PROTEIN RCE1P; PROTEIN S ISOPRENYLCYSTEINE O METHYLTRANSFERASE; PROTEIN STE24P; PROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME SPECIFICITY; ISOPRENYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANTINEOPLASTIC AGENTS; CATALYSIS; DRUG RESISTANCE, FUNGAL; DRUG SCREENING ASSAYS, ANTITUMOR; ENDOPEPTIDASES; KETONES; MEMBRANE PROTEINS; METALLOENDOPEPTIDASES; PEPTIDES; PROTEASE INHIBITORS; PROTEIN ISOPRENYLATION; PROTEIN METHYLTRANSFERASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SUBSTRATE SPECIFICITY;

EID: 34249690834     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2007.03.004     Document Type: Article

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