Conformation-sensitive antibodies against Alzheimer amyloid-β by immunization with a thioredoxin-constrained B-cell epitope peptide

Journal of Biological Chemistry

Volumn 282, Issue 15, 2007, Pages 11436-11445

  Moretto, Nadia ^a   Bolchi, Angelo ^a   Rivetti, Claudio ^a   Imbimbo, Bruno P ^a   Villetti, Gino ^a   Pietrini, Vladimiro ^a   Polonelli, Luciano ^a   Del Signore, Steven ^b,c   Smith, Karen M ^b,c   Ferrante, Robert J ^b,c   Ottonello, Simone ^a,d  

^a UNIVERSITY OF PARMA   (Italy)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Parco Area Delle Scienze 23/A ^*  (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CONFORMATIONS; DISEASES; IMMUNIZATION; PEPTIDES;

ALZHEIMER AMYLOID; ALZHEIMER DISEASE (AD); CONFORMATION-SENSITIVE ANTIBODIES; IMMUNOTHERAPY;

ANTIBODIES;

ALUMINUM; AMYLOID BETA PROTEIN; EPITOPE; PEPTIDE DERIVATIVE; THIOREDOXIN; ANTIBODY; PEPTIDE FRAGMENT; RECOMBINANT PROTEIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; IMMUNIZATION; IMMUNOGENICITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BAGG ALBINO MOUSE; BRAIN; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; IMMUNOLOGY; METABOLISM; PATHOLOGY; PROTEIN TERTIARY STRUCTURE; TRANSGENIC MOUSE;

BACTERIA (MICROORGANISMS); MUS;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; ANTIBODIES; BRAIN; EPITOPES, B-LYMPHOCYTE; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; THIOREDOXIN;

EID: 34249676805     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M609690200     Document Type: Article

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