Cytotoxicity of Insulin within its Self-assembly and Amyloidogenic Pathways

Journal of Molecular Biology

Volumn 370, Issue 2, 2007, Pages 372-384

  Grudzielanek, Stefan ^a   Velkova, Aleksandra ^b   Shukla, Anuj ^a   Smirnovas, Vytautas ^a   Tatarek Nossol, Marianna ^b   Rehage, Heinz ^a   Kapurniotu, Aphrodite ^b   Winter, Roland ^a  

^a TU DORTMUND UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

aggregate polymorphism; amyloid; cosolvent effects; cytotoxicity; insulin

Indexed keywords

ALCOHOL; AMYLOID; DIMER; INSULIN; INSULIN DERIVATIVE; MONOMER; OLIGOMER; THIOFLAVINE;

ANIMAL CELL; ARTICLE; ATOMIC FORCE MICROSCOPY; BETA SHEET; CELL CULTURE; CELL KINETICS; CELL VIABILITY; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG CYTOTOXICITY; FLUORESCENCE; IN VITRO STUDY; INFRARED SPECTROSCOPY; INSULINOMA; LIGHT SCATTERING; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; RAT; SOLVATION;

RATTUS;

EID: 34249674524     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2007.04.053     Document Type: Article

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