Insulin at pH 2: Structural analysis of the conditions promoting insulin fibre formation

Journal of Molecular Biology

Volumn 318, Issue 2, 2002, Pages 479-490

  Whittingham, Jean L ^a   Scott, David J ^a   Chance, Karen ^a   Wilson, Ashley ^a   Finch, John ^b   Brange, Jens ^c   Guy Dodson, G ^a  

^a UNIVERSITY OF YORK   (United Kingdom)

^b Laboratory of Molecular Biology   (United Kingdom)

^c Brange Consult   (Denmark)

Author keywords

Crystal structure; Fibrillation; Insulin; Low pH; Sulphate ions

Indexed keywords

ACETIC ACID; DIMER; INORGANIC ACID; INSULIN; SULFATE; SULFURIC ACID;

ARTICLE; CRYSTAL STRUCTURE; HEATING; HUMAN; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; PH; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STABILITY; STRUCTURE ANALYSIS; TRANSMISSION ELECTRON MICROSCOPY; ULTRACENTRIFUGATION;

EID: 0036304350     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00021-9     Document Type: Article

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