Improved activity and stability of lysozyme at the water/CH2Cl2 interface: Enzyme unfolding and aggregation and its prevention by polyols

Journal of Pharmacy and Pharmacology

Volumn 53, Issue 9, 2001, Pages 1217-1226

  Perez C ^a   Griebenow, K ^a  

^a UNIVERSITY OF PUERTO RICO   (Puerto Rico)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID ETHYL ESTER; DICHLOROMETHANE; EGG WHITE; EXCIPIENT; LYSOZYME; MICROSPHERE; POLYGLACTIN; POLYOL; WATER;

AQUEOUS SOLUTION; ARTICLE; BETA SHEET; CHEMICAL REACTION; CONCENTRATION (PARAMETERS); COVALENT BOND; DRUG DOSAGE FORM; DRUG INHIBITION; DRUG STABILITY; ENCAPSULATION; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME INACTIVATION; ENZYME STABILITY; EXPOSURE; HEN; INFRARED SPECTROSCOPY; MODEL; MOLECULE; PROTEIN AGGREGATION; STRUCTURE ANALYSIS; SURFACE PROPERTY; SUSTAINED RELEASE FORMULATION;

DELAYED-ACTION PREPARATIONS; METHYLENE CHLORIDE; MICROSPHERES; MURAMIDASE; POLYGLACTIN 910; POLYMERS; PROTEINS; SOLVENTS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; WATER;

EID: 0034807911     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357011776667     Document Type: Article

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