Metabotropic P2Y receptors inhibit P2X 3 receptor-channels via G protein-dependent facilitation of their desensitization

British Journal of Pharmacology

Volumn 151, Issue 2, 2007, Pages 226-236

  Gerevich, Z ^a   Zadori, Z ^a,b   Muller C ^a   Wirkner, K ^a   Schroder W ^c   Rubini, P ^a   Illes, P ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b SEMMELWEIS UNIVERSITY   (Hungary)

^c GRÜNENTHAL GMBH   (Germany)

Author keywords

Desensitisation; DRG; G protein; HEK293 cells; P2X 3 receptor; P2Y receptor

Indexed keywords

ADENOSINE TRIPHOSPHATE; GUANINE NUCLEOTIDE BINDING PROTEIN; METABOTROPIC RECEPTOR; PURINE P2X3 RECEPTOR; PURINE P2Y RECEPTOR;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL STRAIN HEK293; CELL TYPE; CONTROLLED STUDY; DESENSITIZATION; EMBRYO; FACILITATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; RAT; SPINAL GANGLION;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; ANIMALS, NEWBORN; CELL LINE; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GANGLIA, SPINAL; GTP-BINDING PROTEINS; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HUMANS; MALE; MEMBRANE POTENTIALS; NEURONS; PATCH-CLAMP TECHNIQUES; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P2; THIONUCLEOTIDES; TIME FACTORS; TRANSFECTION;

EID: 34248591420     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707217     Document Type: Article

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