Importance of DNA-adduct formation and gene expression profiling of disease candidate genes in rats exposed to bitumen fumes

Journal of Occupational and Environmental Hygiene

Volumn 4, Issue SUPPL.1, 2007, Pages 44-64

  Halter, Roman ^a   Hansen, Tanja ^a   Seidel, Albrecht ^b   Ziemann, Christina ^a   Borlak, Jürgen ^a  

^a FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

^b Biochemical Institute for Environmental Carcinogens   (Germany)

Author keywords

Bitumen fumes; DNA adducts; Gene expression; Micronucleus assay; PAH metabolites

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; 1 NAPHTHOL; ASPHALT; CATHEPSIN D; CATHEPSIN K; CYTOCHROME P450; CYTOCHROME P450 1A1; GUANINE NUCLEOTIDE BINDING PROTEIN; NUCLEOTIDE; PHOSPHORUS 32; POLYCYCLIC AROMATIC HYDROCARBON; PYRENE; PYRENE DERIVATIVE; UNSPECIFIC MONOOXYGENASE;

AMBIENT AIR; ANIMAL CELL; BLOOD SMEAR; BONE MARROW CELL; CATALYSIS; CONCENTRATION (PARAMETERS); CONFERENCE PAPER; CONTROLLED STUDY; DNA ADDUCT; DOSE RESPONSE; ERYTHROCYTE; ERYTHROCYTE COUNT; EXPOSURE; GENE EXPRESSION PROFILING; GENE FUNCTION; GENETIC REGULATION; GENOTOXICITY; INFLAMMATION; ISOTOPE LABELING; LEUKOCYTE; LUNG; LUNG ALVEOLUS EPITHELIUM; LUNG DISEASE; MALE; METABOLIC ACTIVATION; METABOLITE; NONHUMAN; NOSE MUCOSA; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TARGET ORGAN; URINARY EXCRETION;

EID: 34248576089     PISSN: 15459624     EISSN: 15459632     Source Type: Journal    
DOI: 10.1080/15459620701337528     Document Type: Conference Paper

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