Epithelial Na, K-ATPase expression is down-regulated in canine prostate cancer; a possible consequence of metabolic transformation in the process of prostate malignancy

Cancer Cell International

Volumn 3, Issue , 2003, Pages

  Mobasheri, Ali ^a   Fox, Richard ^a   Evans, Iain ^a   Cullingham, Fay ^a   Martín Vasallo, Pablo ^b   Foster, Christopher S ^c  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b UNIVERSIDAD DE LA LAGUNA   (Spain)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Benign prostatic hyperplasia; Canine prostate; Citrate metabolism; Isoform; K ATPase; Malignancy; Metabolic transformation; Na; Prostate cancer

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CITRIC ACID; ISOENZYME;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; BASOLATERAL MEMBRANE; CANCER CELL; CELL FUNCTION; CELL MEMBRANE; CELL METABOLISM; CELL STRUCTURE; CONTROLLED STUDY; DOG DISEASE; DOWN REGULATION; ENZYME SUBUNIT; IMMUNOHISTOCHEMISTRY; KIDNEY; MALE; MALIGNANT TRANSFORMATION; NONHUMAN; PROSTATE ADENOCARCINOMA; PROSTATE CANCER; PROSTATE EPITHELIUM; PROSTATE HYPERTROPHY; PROTEIN EXPRESSION;

EID: 2942609688     PISSN: 14752867     EISSN: None     Source Type: Journal    
DOI: 10.1186/1475-2867-3-8     Document Type: Article

References (36)

1. Costello LC and Franklin RB: Citrate metabolism of normal and malignant prostate epithelial cells Urology 1997, 50:3-12.
2. Kavanagh JP: Sodium, potassium, calcium, magnesium, zinc, citrate and chloride content of human prostatic and seminal fluid J Reprod Fertil 1985, 75:35-41.
3. Franklin RB, Lao LX and Costello LC: Evidence for two aspartate transport systems in prostate epithelial cells Prostate 1990, 16:137-45.
4. Costello LC and Franklin RB: The intermediary metabolism of the prostate: a key to understanding the pathogenesis and progression of prostate malignancy Oncology 2000, 59:269-82.
5. Smith ER: The secretion of electrolytes by the pilocarpine-stimulated canine prostate gland Proc Soc Exp Biol Med 1969, 132:223-6.
6. Farnsworth WE: Androgen regulation of prostatic membrane ATPase Biol Reprod 1970, 3:218-22.
7. Farnsworth WE: Na+, K(+)-ATPase: the actual androgen receptor of the prostate? Med Hypotheses 1993, 41:358-62.
8. Blok LJ, de Ruiter PE and Brinkmann AO: Forskolin-induced dephosphorylation of the androgen receptor impairs ligand binding Biochemistry 1998, 37:3850-7.
9. Blok LJ, Chang GT, Steenbeek-Slotboom M, van Weerden WM, Swarts HG, De Pont JJ, van Steenbrugge GJ and Brinkmann AO: Regulation of expression of Na+, K+-ATPase in androgendependent and androgen-independent prostate cancer Br J Cancer 1999, 81:28-36.
10. Blanco G and Mercer RW: Isozymes of the Na-K-ATPase: heterogeneity in structure, diversity in function Am J Physiol 1998, 275:F633-50.
11. Mobasheri A, Avila J, Cozar-Castellano I, Brownleader MD, Trevan M, Francis MJ, Lamb JF and Martin-Vasallo P: Na+, K+-ATPase isozyme diversity; comparative biochemistry and physiological implications of novel functional interactions Biosci Rep 2000, 20:51-91.
12. Scheiner-Bobis G, Meyer zu Heringdorf D, Christ M and Habermann E: Palytoxin induces K+ efflux from yeast cells expressing the mammalian sodium pump Mol Pharmacol 1994, 45:1132-6.
13. Shamraj OI and Lingrel JB: A putative fourth Na+, K(+)-ATPase alpha-subunit gene is expressed in testis Proc Natl Acad Sci U S A 1994, 91:12952-6.
14. Woo AL, James PF and Lingrel JB: Sperm motility is dependent on a unique isoform of the Na, K-ATPase J Biol Chem 2000, 275:20693-9.
15. Mercer RW, Biemesderfer D, Bliss DP Jr, Collins JH and Forbush B 3rd: Molecular cloning and immunological characterization of the gamma polypeptide, a small protein associated with the Na, K-ATPase J Cell Biol 1993, 121:579-86.
16. Beguin P, Wang X, Firsov D, Puoti A, Claeys D, Horisberger JD and Geering K: The gamma subunit is a specific component of the Na, K-ATPase and modulates its transport function Embo J 1997, 16:4250-60.
17. Sweadner KJ and Rael E: The FXYD gene family of small ion transport regulators or channels: cDNA sequence, protein signature sequence, and expression Genomics 2000, 68:41-56.
18. Arystarkhova E, Wetzel RK, Asinovski NK and Sweadner KJ: The gamma subunit modulates Na(+) and K(+) affinity of the renal Na, K-ATPase J Biol Chem 1999, 274:33183-5.
19. Kuster B, Shainskaya A, Pu HX, Goldshleger R, Blostein R, Mann M and Karlish SJ: A new variant of the gamma subunit of renal Na, K-ATPase. Identification by mass spectrometry, antibody binding, and expression in cultured cells J Biol Chem 2000, 275:18441-6.
20. Mobasheri A, Oukrif D, Dawodu SP, Sinha M, Greenwell P, Stewart D, Djamgoz MB, Foster CS, Martin-Vasallo P and Mobasheri R: Isoforms of Na+, K+-ATPase in human prostate; specificity of expression and apical membrane polarization Histol Histopathol 2001, 16:141-54.
21. Choi Y, Dubel SJ, Pacioaiou ML, Omori A, Ito T, Copeland TD, Takahashi M and McEnery MW: Parallel detection of Na, K-ATPase alpha subunit isoforms by pan-specific monoclonal mAb 9A7 Arch Biochem Biophys 1997, 344:165-75.
22. Schmidt JD, Gibbons RP, Murphy GP and Bartolucci A: Adjuvant therapy for localized prostate cancer Cancer 1993, 71:1005-13.
23. Laniado ME, Lalani EN, Fraser SP, Grimes JA, Bhangal G, Djamgoz MB and Abel PD: Expression and functional analysis of voltage-activated Na+ channels in human prostate cancer cell lines and their contribution to invasion in vitro Am J Pathol 1997, 150:1213-21.
24. Smith P, Rhodes NP, Shortland AP, Fraser SP, Djamgoz MB, Ke Y and Foster CS: Sodium channel protein expression enhances the invasiveness of rat and human prostate cancer cells FEBS Lett 1998, 423:19-24.
25. Foster CS, Cornford P, Forsyth L, Djamgoz MB and Ke Y: The cellular and molecular basis of prostate cancer BJU Int 1999, 83:171-94.
26. Sandstrom PE, Jonsson O, Grankvist K and Henriksson R: Identification of potassium flux pathways and their role in the cytotoxicity of estramustine in human malignant glioma, prostatic carcinoma and pulmonary carcinoma cell lines Eur J Cancer 1994, 30A:1822-6.
27. Fraser SP, Ding Y, Liu A, Foster CS and Djamgoz MB: Tetrodotoxin suppresses morphological enhancement of the metastatic MAT-LyLu rat prostate cancer cell line Cell Tissue Res 1999, 295:505-12.
28. Abdul M and Hoosein N: Voltage-gated sodium ion channels in prostate cancer: expression and activity Anticancer Res 2002, 22:1727-30.
29. Djamgoz MBA, Mycielska M, Madeja Z, Fraser SP and Korohoda W: Directional movement of rat prostate cancer cells in direct-current electric field: involvement of voltagegated Na+ channel activity J Cell Sci 2001, 114:2697-705.
30. Foster CS and Ke Y: Stem cells in prostatic epithelia Int J Exp Pathol 1997, 78:311-29.
31. Espineda C, Seligson DB, James Ball W Jr, Rao J, Palotie A, Horvath S, Huang Y, Shi T and Rajasekaran AK: Analysis of the Na, K-ATPase alpha- and beta-subunit expression profiles of bladder cancer using tissue microarrays Cancer 2003, 97:1859-68.
32. Takeyasu K, Tamkun MM, Renaud KJ and Fambrough DM: Ouabain-sensitive (Na+ + K+)-ATPase activity expressed in mouse L cells by transfection with DNA encoding the alpha-subunit of an avian sodium pump J Biol Chem 1988, 263:4347-54.
33. Gottardi CJ and Caplan MJ: Molecular requirements for the cell-surface expression of multisubunit ion-transporting ATPases. Identification of protein domains that participate in Na, K-ATPase and H, K-ATPase subunit assembly J Biol Chem 1993, 268:14342-7.
34. Urayama O, Shutt H and Sweadner KJ: Identification of three isozyme proteins of the catalytic subunit of the Na, K-ATPase in rat brain J Biol Chem 1989, 264:8271-80.
35. Arystarkhova E and Sweadner KJ: Isoform-specific monoclonal antibodies to Na, K-ATPase alpha subunits. Evidence for a tissue-specific post-translational modification of the alpha subunit J Biol Chem 1996, 271:23407-17.
36. Gonzalez-Martinez LM, Avila J, Marti E, Lecuona E and Martin-Vasallo P: Expression of the beta-subunit isoforms of the Na, KATPase in rat embryo tissues, inner ear and choroid plexus Biol Cell 1994, 81:215-22.