메뉴 건너뛰기




Volumn 18, Issue 1, 2007, Pages 46-57

Ouabain binds with high affinity to the Na,K-ATPase in human polycystic kidney cells and induces extracellular signal-regulated kinase activation and cell proliferation

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE; OUABAIN;

EID: 33845977762     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1681/ASN.2006010086     Document Type: Article
Times cited : (76)

References (50)
  • 2
    • 0035133295 scopus 로고    scopus 로고
    • Sodium-potassium-adenosinetriphos-phatase-dependent sodium transport in the kidney: Hormonal control
    • Feraille E, Doucet A: Sodium-potassium-adenosinetriphos-phatase-dependent sodium transport in the kidney: Hormonal control. Physiol Rev 81: 345-418, 2001
    • (2001) Physiol Rev , vol.81 , pp. 345-418
    • Feraille, E.1    Doucet, A.2
  • 3
    • 28644447041 scopus 로고    scopus 로고
    • Na,K-ATPase subunit heterogeneity as a mechanism for tissue-specific ion regulation
    • Blanco G: Na,K-ATPase subunit heterogeneity as a mechanism for tissue-specific ion regulation. Semin Nephrol 25: 292-303, 2005
    • (2005) Semin Nephrol , vol.25 , pp. 292-303
    • Blanco, G.1
  • 5
    • 0034662757 scopus 로고    scopus 로고
    • The FXYD gene family of small ion transport regulators or channels: CDNA sequence, protein signature sequence, and expression
    • Sweadner KJ, Rael E: The FXYD gene family of small ion transport regulators or channels: cDNA sequence, protein signature sequence, and expression. Genomics 68: 41-56, 2000
    • (2000) Genomics , vol.68 , pp. 41-56
    • Sweadner, K.J.1    Rael, E.2
  • 6
    • 0031852360 scopus 로고    scopus 로고
    • The cellular mechanism of action of cardiotonic steroids: A new hypothesis
    • Blaustein MP, Juhaszova M, Golovina VA: The cellular mechanism of action of cardiotonic steroids: A new hypothesis. Clin Exp Hypertens 20: 691-703, 1998
    • (1998) Clin Exp Hypertens , vol.20 , pp. 691-703
    • Blaustein, M.P.1    Juhaszova, M.2    Golovina, V.A.3
  • 8
    • 0036106788 scopus 로고    scopus 로고
    • Endogenous cardiac glycosides, a new class of steroid hormones
    • Schoner W: Endogenous cardiac glycosides, a new class of steroid hormones. Eur J Biochem 269: 2440-2448, 2002
    • (2002) Eur J Biochem , vol.269 , pp. 2440-2448
    • Schoner, W.1
  • 9
    • 0038239865 scopus 로고    scopus 로고
    • Low concentrations of ouabain activate vascular smooth muscle cell proliferation
    • Allen JC, Abramowitz J, Koksoy A: Low concentrations of ouabain activate vascular smooth muscle cell proliferation. Ann N Y Acad Sci 986: 504-508, 2003
    • (2003) Ann N Y Acad Sci , vol.986 , pp. 504-508
    • Allen, J.C.1    Abramowitz, J.2    Koksoy, A.3
  • 10
    • 0034977171 scopus 로고    scopus 로고
    • Dual effects of ouabain on the regulation of proliferation and apoptosis in human prostatic smooth muscle cells
    • Chueh SC, Guh JH, Chen J, Lai MK, Teng CM: Dual effects of ouabain on the regulation of proliferation and apoptosis in human prostatic smooth muscle cells. J Urol 166: 347-353, 2001
    • (2001) J Urol , vol.166 , pp. 347-353
    • Chueh, S.C.1    Guh, J.H.2    Chen, J.3    Lai, M.K.4    Teng, C.M.5
  • 11
    • 0032511095 scopus 로고    scopus 로고
    • Multiple signal transduction pathways link Na+/K+-AT-Pase to growth-related genes in cardiac myocytes. The roles of Ras and mitogen-activated protein kinases
    • Kometiani P, Li J, Gnudi L, Kahn BB, Askari A, Xie Z: Multiple signal transduction pathways link Na+/K+-AT-Pase to growth-related genes in cardiac myocytes. The roles of Ras and mitogen-activated protein kinases. J Biol Chem 273: 15249-15256, 1998
    • (1998) J Biol Chem , vol.273 , pp. 15249-15256
    • Kometiani, P.1    Li, J.2    Gnudi, L.3    Kahn, B.B.4    Askari, A.5    Xie, Z.6
  • 12
    • 0037381166 scopus 로고    scopus 로고
    • Positive inotropic effect of ouabain on isolated heart is accompanied by activation of signal pathways that link Na+/K+-ATPase to ERK1/2
    • Mohammadi K, Liu L, Tian J, Kometiani P, Xie Z, Askari A: Positive inotropic effect of ouabain on isolated heart is accompanied by activation of signal pathways that link Na+/K+-ATPase to ERK1/2. J Cardiovasc Pharmacol 41: 609-614, 2004
    • (2004) J Cardiovasc Pharmacol , vol.41 , pp. 609-614
    • Mohammadi, K.1    Liu, L.2    Tian, J.3    Kometiani, P.4    Xie, Z.5    Askari, A.6
  • 14
    • 0041344556 scopus 로고    scopus 로고
    • Ouabain is a potent promoter of growth and activator of ERK1/2 in ouabain-resistant rat renal epithelial cells
    • Dmitrieva RI, Doris PA: Ouabain is a potent promoter of growth and activator of ERK1/2 in ouabain-resistant rat renal epithelial cells. J Biol Chem 278: 28160-28166, 2002
    • (2002) J Biol Chem , vol.278 , pp. 28160-28166
    • Dmitrieva, R.I.1    Doris, P.A.2
  • 15
    • 2342487353 scopus 로고    scopus 로고
    • Na+-K+-ATPase-mediated signal transduction: From protein interaction to cellular function
    • Xie Z, Cai T: Na+-K+-ATPase-mediated signal transduction: From protein interaction to cellular function. Mol Interv 3: 157-168, 2003
    • (2003) Mol Interv , vol.3 , pp. 157-168
    • Xie, Z.1    Cai, T.2
  • 16
    • 0037320210 scopus 로고    scopus 로고
    • Autosomal dominant polycystic kidney disease: Molecular genetics and pathophysiology
    • Sutters M, Germino GG: Autosomal dominant polycystic kidney disease: Molecular genetics and pathophysiology. J Lab Clin Med 14: 91-101, 2003
    • (2003) J Lab Clin Med , vol.14 , pp. 91-101
    • Sutters, M.1    Germino, G.G.2
  • 17
    • 0347357836 scopus 로고    scopus 로고
    • Polycystic kidney disease
    • Wilson PD: Polycystic kidney disease. N Engl J Med 350: 151-164, 2004
    • (2004) N Engl J Med , vol.350 , pp. 151-164
    • Wilson, P.D.1
  • 18
    • 16244414299 scopus 로고    scopus 로고
    • Molecular pathogenesis of ADPKD: The polycystin complex gets complex
    • Ong AC, Harris PC: Molecular pathogenesis of ADPKD: The polycystin complex gets complex. Kidney Int 67:1234-1247, 2005
    • (2005) Kidney Int , vol.67 , pp. 1234-1247
    • Ong, A.C.1    Harris, P.C.2
  • 19
    • 0032949167 scopus 로고    scopus 로고
    • New insights into the molecular pathophysiology of polycystic kidney disease
    • Murcia NS, Sweeney WE Jr, Avner ED: New insights into the molecular pathophysiology of polycystic kidney disease. Kidney Int 55: 1187-1197, 1999
    • (1999) Kidney Int , vol.55 , pp. 1187-1197
    • Murcia, N.S.1    Sweeney Jr, W.E.2    Avner, E.D.3
  • 20
    • 20044369017 scopus 로고    scopus 로고
    • Molecular basis of autosomal dominant polycystic kidney disease
    • Al-Bhalal L, Akhtar M: Molecular basis of autosomal dominant polycystic kidney disease. Adv Anal Pathol 55: 126-133, 2005
    • (2005) Adv Anal Pathol , vol.55 , pp. 126-133
    • Al-Bhalal, L.1    Akhtar, M.2
  • 22
    • 0026935809 scopus 로고
    • Cyst fluid from human autosomal dominant polycystic kidneys promotes cyst formation and expansion by renal epithelial cells in vitro
    • Ye M, Grant M, Sharma M, Elzinga L, Swan S, Torres VE, Grantham JJ: Cyst fluid from human autosomal dominant polycystic kidneys promotes cyst formation and expansion by renal epithelial cells in vitro. J Am Soc Nephrol 3: 984-994, 1992
    • (1992) J Am Soc Nephrol , vol.3 , pp. 984-994
    • Ye, M.1    Grant, M.2    Sharma, M.3    Elzinga, L.4    Swan, S.5    Torres, V.E.6    Grantham, J.J.7
  • 23
    • 0344527449 scopus 로고    scopus 로고
    • Functional activity of epidermal growth factor receptors in autosomal recessive polycystic kidney disease
    • Sweeney WE Jr, Avner ED: Functional activity of epidermal growth factor receptors in autosomal recessive polycystic kidney disease. Am J Physiol 275: F387-F394, 1998
    • (1998) Am J Physiol , vol.275
    • Sweeney Jr, W.E.1    Avner, E.D.2
  • 27
    • 0031753210 scopus 로고    scopus 로고
    • Epithelial transport in polycystic kidney disease
    • Sullivan LP, Wallace DP, Grantham JJ: Epithelial transport in polycystic kidney disease. Physiol Rev 78: 1165-1191, 1998
    • (1998) Physiol Rev , vol.78 , pp. 1165-1191
    • Sullivan, L.P.1    Wallace, D.P.2    Grantham, J.J.3
  • 29
    • 0026935809 scopus 로고
    • Cyst fluid from human autosomal dominant polycystic kidneys promotes cyst formation and expansion by renal epithelial cells in vitro
    • Ye M, Grant M, Sharma M, Elzinga L, Swan S, Torres VE, Grantham JJ: Cyst fluid from human autosomal dominant polycystic kidneys promotes cyst formation and expansion by renal epithelial cells in vitro. J Am Soc Nephrol 4: 984-994, 1992
    • (1992) J Am Soc Nephrol , vol.4 , pp. 984-994
    • Ye, M.1    Grant, M.2    Sharma, M.3    Elzinga, L.4    Swan, S.5    Torres, V.E.6    Grantham, J.J.7
  • 30
    • 0029806301 scopus 로고    scopus 로고
    • Chloride and fluid secretion by cultured human polycystic kidney cells
    • Wallace DP, Grantham JJ, Sullivan LP: Chloride and fluid secretion by cultured human polycystic kidney cells. Kidney Int 50: 1327-1336, 1996
    • (1996) Kidney Int , vol.50 , pp. 1327-1336
    • Wallace, D.P.1    Grantham, J.J.2    Sullivan, L.P.3
  • 31
    • 0028865916 scopus 로고
    • Characterization of Na,K-ATPase isoform expression and activity in MDCK and Caco-2 epithelial cells
    • Grindstaff KK, Blanco G, Mercer RW: Characterization of Na,K-ATPase isoform expression and activity in MDCK and Caco-2 epithelial cells. Epithelial Cell Biol 4:17-24, 1995
    • (1995) Epithelial Cell Biol , vol.4 , pp. 17-24
    • Grindstaff, K.K.1    Blanco, G.2    Mercer, R.W.3
  • 32
  • 33
    • 27844454873 scopus 로고    scopus 로고
    • Different expression and activity of the alphal and alpha4 isoforms of the Na,K-ATPase during rat male germ cell ontogeny
    • Wagoner K, Sanchez G, Nguyen AN, Enders GC, Blanco G: Different expression and activity of the alphal and alpha4 isoforms of the Na,K-ATPase during rat male germ cell ontogeny. Reproduction 130: 627-641, 2005
    • (2005) Reproduction , vol.130 , pp. 627-641
    • Wagoner, K.1    Sanchez, G.2    Nguyen, A.N.3    Enders, G.C.4    Blanco, G.5
  • 34
    • 0037155802 scopus 로고    scopus 로고
    • Differential regulation of renal Na,K-ATPase by splice variants of the gamma subunit
    • Arystarkhova E, Donnet C, Asinovski NK, Sweadner KJ: Differential regulation of renal Na,K-ATPase by splice variants of the gamma subunit. J Biol Chem 277: 10162-10172, 2002
    • (2002) J Biol Chem , vol.277 , pp. 10162-10172
    • Arystarkhova, E.1    Donnet, C.2    Asinovski, N.K.3    Sweadner, K.J.4
  • 35
    • 0029076753 scopus 로고
    • A critical assessment of the use of microculture tetrazolium assays to measure cell growth and function
    • Marshall NJ, Goodwin CJ, Holt SJ: A critical assessment of the use of microculture tetrazolium assays to measure cell growth and function. Growth Regul 5: 69-84, 1995
    • (1995) Growth Regul , vol.5 , pp. 69-84
    • Marshall, N.J.1    Goodwin, C.J.2    Holt, S.J.3
  • 36
    • 0028984539 scopus 로고
    • Comparison of the enzymatic properties of the Na,K-ATPase alpha3beta1 and alpha3beta2 isozymes
    • Blanco G, Sanchez G, Mercer RW: Comparison of the enzymatic properties of the Na,K-ATPase alpha3beta1 and alpha3beta2 isozymes. Biochem 34: 9897-9903, 1995
    • (1995) Biochem , vol.34 , pp. 9897-9903
    • Blanco, G.1    Sanchez, G.2    Mercer, R.W.3
  • 37
    • 0034791330 scopus 로고    scopus 로고
    • All human Na,K-ATPase alpha subunit isoforms have a similar affinity for cardiac glycosides
    • Wang J, Velotta JB, McDonough AA, Farley RA: All human Na,K-ATPase alpha subunit isoforms have a similar affinity for cardiac glycosides. Am J Physiol 281: C1336-C1343, 2001
    • (2001) Am J Physiol , vol.281
    • Wang, J.1    Velotta, J.B.2    McDonough, A.A.3    Farley, R.A.4
  • 38
    • 33745818598 scopus 로고    scopus 로고
    • Low doses of ouabain protect from serum deprivation-triggered apoptosis and stimulate kidney cell proliferation via activation of NF-kappaB
    • Li J, Zelenin S, Aperia A, Aizman O: Low doses of ouabain protect from serum deprivation-triggered apoptosis and stimulate kidney cell proliferation via activation of NF-kappaB. J Am Soc Nephrol 17: 1848-1857, 2006
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1848-1857
    • Li, J.1    Zelenin, S.2    Aperia, A.3    Aizman, O.4
  • 39
    • 0033883799 scopus 로고    scopus 로고
    • Apical plasma membrane mispolarization of NaK-ATPase in polycystic kidney disease epithelia is associated with aberrant expression of the beta2 isoform
    • Wilson PD, Devuyst O, Li X, Gatti L, Falkenstein D, Robinson S, Fambrough D, Burrow CR: Apical plasma membrane mispolarization of NaK-ATPase in polycystic kidney disease epithelia is associated with aberrant expression of the beta2 isoform. Am J Pathol 156: 253-268, 2000
    • (2000) Am J Pathol , vol.156 , pp. 253-268
    • Wilson, P.D.1    Devuyst, O.2    Li, X.3    Gatti, L.4    Falkenstein, D.5    Robinson, S.6    Fambrough, D.7    Burrow, C.R.8
  • 41
    • 27644588398 scopus 로고    scopus 로고
    • The C-terminal tail of the polycystin-1 protein interacts with the Na,K-ATPase alpha-subunit
    • Zatti A, Chauvet V, Rajendran V, Kimura T, Pagel P, Caplan MJ: The C-terminal tail of the polycystin-1 protein interacts with the Na,K-ATPase alpha-subunit. Mol Biol Cell 16: 5087-5093, 2005
    • (2005) Mol Biol Cell , vol.16 , pp. 5087-5093
    • Zatti, A.1    Chauvet, V.2    Rajendran, V.3    Kimura, T.4    Pagel, P.5    Caplan, M.J.6
  • 42
    • 21344443929 scopus 로고    scopus 로고
    • The Na,K-ATPase and its isozymes: What we have learned using the baculovirus expression system
    • Blanco G: The Na,K-ATPase and its isozymes: What we have learned using the baculovirus expression system. Front Biosci 10: 2397-2411, 2005
    • (2005) Front Biosci , vol.10 , pp. 2397-2411
    • Blanco, G.1
  • 43
    • 4644367485 scopus 로고    scopus 로고
    • Calcium restriction allows cAMP activation of the B-Raf/ERK pathway, switching cells to a cAMP-dependent growth-stimulated phenotype
    • Yamaguchi T, Wallace DP, Magenheimer BS, Hempson SJ, Grantham JJ, Calvet J: Calcium restriction allows cAMP activation of the B-Raf/ERK pathway, switching cells to a cAMP-dependent growth-stimulated phenotype. J Biol Chem 279: 40419-40430, 2004
    • (2004) J Biol Chem , vol.279 , pp. 40419-40430
    • Yamaguchi, T.1    Wallace, D.P.2    Magenheimer, B.S.3    Hempson, S.J.4    Grantham, J.J.5    Calvet, J.6
  • 44
    • 0036224417 scopus 로고    scopus 로고
    • Cellular functions of plasma membrane estrogen receptors
    • Levin ER: Cellular functions of plasma membrane estrogen receptors. Steroids 67: 471-475, 2002
    • (2002) Steroids , vol.67 , pp. 471-475
    • Levin, E.R.1
  • 45
    • 0347723919 scopus 로고    scopus 로고
    • Estradiol binding to maxi-K channels induces their down-regulation via proteasomal degradation
    • Korovkina VP, Brainard AM, Ismail P, Schmidt TJ, England SK: Estradiol binding to maxi-K channels induces their down-regulation via proteasomal degradation. J Biol Chem 279: 1217-1223, 2004
    • (2004) J Biol Chem , vol.279 , pp. 1217-1223
    • Korovkina, V.P.1    Brainard, A.M.2    Ismail, P.3    Schmidt, T.J.4    England, S.K.5
  • 46
    • 0034584728 scopus 로고    scopus 로고
    • Aldosterone- and progesterone-membrane-binding proteins: New concepts of nongenomic steroid action
    • Haseroth K, Christ M, Falkenstein E, Wehling M: Aldosterone- and progesterone-membrane-binding proteins: New concepts of nongenomic steroid action. Curr Protein Pept Sci 1: 385-401, 2000
    • (2000) Curr Protein Pept Sci , vol.1 , pp. 385-401
    • Haseroth, K.1    Christ, M.2    Falkenstein, E.3    Wehling, M.4
  • 47
    • 0025604929 scopus 로고
    • A comparison of the affinities of rat (Na+ + K+)-ATPase isozymes for cardioactive steroids, role of lactone ring, sugar moiety and KCl concentration
    • Noel F, Fagoo M, Godfraind T: A comparison of the affinities of rat (Na+ + K+)-ATPase isozymes for cardioactive steroids, role of lactone ring, sugar moiety and KCl concentration. Biochem Pharmacol 40: 2611-2616, 1990
    • (1990) Biochem Pharmacol , vol.40 , pp. 2611-2616
    • Noel, F.1    Fagoo, M.2    Godfraind, T.3
  • 48
    • 85190658146 scopus 로고    scopus 로고
    • Cowley BD Jr, Rupp JC, Muessel MJ, Gattone VH 2nd: Gender and the effect of gonadal hormones on the progression of inherited polycystic kidney disease in rats. Am J Kidney Dis 29: 265-272, 1997
    • Cowley BD Jr, Rupp JC, Muessel MJ, Gattone VH 2nd: Gender and the effect of gonadal hormones on the progression of inherited polycystic kidney disease in rats. Am J Kidney Dis 29: 265-272, 1997


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.