A high-throughput assay for the adenylation reaction of bacterial DNA ligase

Analytical Biochemistry

Volumn 366, Issue 1, 2007, Pages 9-17

  Miesel, Lynn ^a   Kravec, Cynthia ^a   Xin, Alan Tianpei ^a   McMonagle, Patricia ^a   Ma, Sarah ^a   Pichardo, John ^a   Feld, Boris ^a   Barrabee, Ellen ^a   Palermo, Robert ^b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Adenylation; Antibacterial; DNA ligase; Enzyme linked immunosorbent assay (ELISA); High throughput screening; Inhibitors; Scintillation proximity assay; Ultra high throughput screening

Indexed keywords

CELL DEATH; CHROMOSOMES; CORROSION INHIBITORS; ENZYMES; ESCHERICHIA COLI; SCINTILLATION;

ADENYLATION; ANTIBACTERIAL; DNA LIGASES; ENZYME LINKED IMMUNOSORBENT ASSAY; HIGH THROUGHPUT SCREENING; ULTRA-HIGH;

DNA;

ADENOSINE DERIVATIVE; ADENOSINE PHOSPHATE; BACTERIAL ENZYME; NICOTINAMIDE ADENINE DINUCLEOTIDE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; STREPTAVIDIN;

ADENYLATION; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; HIGH THROUGHPUT SCREENING; IC 50; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; SCINTILLATION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; EUKARYOTA;

EID: 34248566785     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2007.03.028     Document Type: Article

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