The environmental carcinogen 3-nitrobenzanthrone and its main metabolite 3-aminobenzanthrone enhance formation of reactive oxygen intermediates in human A549 lung epithelial cells

Toxicology and Applied Pharmacology

Volumn 221, Issue 2, 2007, Pages 222-234

  Hansen, Tanja ^a   Seidel, Albrecht ^b   Borlak, Jürgen ^a  

^a FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

^b Prof Dr Gernot Grimmer Foundation   (Germany)

Author keywords

3 aminobenzanthrone; 3 nitrobenzanthrone; cell cycle; diesel exhaust; DNA damage; reactive oxygen species

Indexed keywords

3 AMINOBENZANTHRONE; 3 NITROBENZANTHRONE; ALLOPURINOL; CARCINOGEN; CASPASE; CYTOCHROME P450 1A1; DICHLORODIHYDROFLUORESCEIN DIACETATE; DICHLOROFLUORESCEIN; DICOUMAROL; POLYCYCLIC AROMATIC COMPOUND; PROADIFEN; REACTIVE OXYGEN METABOLITE; RESVERATROL; ROTENONE; THENOYLTRIFLUOROACETONE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER RISK; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CELL PROLIFERATION; CONTAMINATION; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; FLOW CYTOMETRY; GENOTOXICITY; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; LUNG CANCER; TUMOR PROMOTION;

APOPTOSIS; BENZ(A)ANTHRACENES; CARCINOGENS; CELL CYCLE; CELL LINE; CELL PROLIFERATION; CYTOCHROME P-450 CYP1A1; DNA DAMAGE; ENZYME INDUCTION; ENZYME INHIBITORS; EPITHELIAL CELLS; HUMANS; LUNG; REACTIVE OXYGEN SPECIES;

EID: 34248522797     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2007.03.003     Document Type: Article

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