메뉴 건너뛰기




Volumn 47, Issue 7, 2006, Pages 541-552

DNA damage and acute toxicity caused by the urban air pollutant 3-nitrobenzanthrone in rats: Characterization of DNA adducts in eight different tissues and organs with synthesized standards

Author keywords

3 nitrobenzanthrone; Acute toxicity; Air pollutant; DNA adducts; F344 rats; Oral administration

Indexed keywords

3 NITROBENZANTHRONE; CARCINOGEN; DNA; HYDROXYLAMINE; MUTAGENIC AGENT; PHOSPHORUS 32;

EID: 33747893873     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20227     Document Type: Article
Times cited : (15)

References (43)
  • 1
    • 0032408502 scopus 로고    scopus 로고
    • Involvement of interleukin-1 in the development of ulcerative colitis induced by dextran sulfate sodium in mice
    • Arai Y, Takanashi H, Kitagawa H, Okayasu I. 1998. Involvement of interleukin-1 in the development of ulcerative colitis induced by dextran sulfate sodium in mice. Cytokine 10:890-896.
    • (1998) Cytokine , vol.10 , pp. 890-896
    • Arai, Y.1    Takanashi, H.2    Kitagawa, H.3    Okayasu, I.4
  • 2
    • 0023930934 scopus 로고
    • The contribution of nitrofluoranthenes and nitropyrenes to the mutagenic activity of ambient particulate organic matter collected in southern California
    • Arey J, Zielinska B, Harger WP, Atkinson R, Winer AM. 1988. The contribution of nitrofluoranthenes and nitropyrenes to the mutagenic activity of ambient particulate organic matter collected in southern California. Mutat Res 207:45-51.
    • (1988) Mutat Res , vol.207 , pp. 45-51
    • Arey, J.1    Zielinska, B.2    Harger, W.P.3    Atkinson, R.4    Winer, A.M.5
  • 3
    • 0035427209 scopus 로고    scopus 로고
    • DNA adduct formation by the ubiquitous environmental contaminant 3-nitrobenzanthrone in rats determined by (32)P-postlabeling
    • Arlt VM, Bieler CA, Mier W, Wiessler M, Schmeiser HH. 2001. DNA adduct formation by the ubiquitous environmental contaminant 3-nitrobenzanthrone in rats determined by (32)P-postlabeling. Int J Cancer 93:450-454.
    • (2001) Int J Cancer , vol.93 , pp. 450-454
    • Arlt, V.M.1    Bieler, C.A.2    Mier, W.3    Wiessler, M.4    Schmeiser, H.H.5
  • 4
    • 0038724204 scopus 로고    scopus 로고
    • Activation of 3-nitrobenzanthrone and its metabolites by human acetyltransferases, sulfotransferases and cytochrome P450 expressed in Chinese hamster V79 cells
    • Arlt VM, Glatt H, Muckel E, Pabel U, Sorg BL, Seidel A, Frank H, Schmeiser HH, Phillips DH. 2003a. Activation of 3-nitrobenzanthrone and its metabolites by human acetyltransferases, sulfotransferases and cytochrome P450 expressed in Chinese hamster V79 cells. Int J Cancer 105:583-592.
    • (2003) Int J Cancer , vol.105 , pp. 583-592
    • Arlt, V.M.1    Glatt, H.2    Muckel, E.3    Pabel, U.4    Sorg, B.L.5    Seidel, A.6    Frank, H.7    Schmeiser, H.H.8    Phillips, D.H.9
  • 6
    • 2442546368 scopus 로고    scopus 로고
    • DNA adducts and mutagenic specificity of the ubiquitous environmental pollutant 3-nitrobenzanthrone in Muta Mouse
    • Arlt VM, Zhan L, Schmeiser HH, Honma M, Hayashi M, Phillips DH, Suzuki T. 2004. DNA adducts and mutagenic specificity of the ubiquitous environmental pollutant 3-nitrobenzanthrone in Muta Mouse. Environ Mol Mutagen 43:186-195.
    • (2004) Environ Mol Mutagen , vol.43 , pp. 186-195
    • Arlt, V.M.1    Zhan, L.2    Schmeiser, H.H.3    Honma, M.4    Hayashi, M.5    Phillips, D.H.6    Suzuki, T.7
  • 7
    • 20144388221 scopus 로고    scopus 로고
    • Environmental pollutant and potent mutagen 3-nitrobenzanthrone forms DNA adducts after reduction by NAD(P)H:Quinone oxidoreductase and conjugation by acetyltransferases and sulfotransferases in human hepatic cytosols
    • Arlt VM, Stiborova M, Henderson CJ, Osborne MR, Bieler CA, Frei E, Martinek V, Sopko B, Wolf CR, Schmeiser HH, Phillips DH. 2005. Environmental pollutant and potent mutagen 3-nitrobenzanthrone forms DNA adducts after reduction by NAD(P)H:Quinone oxidoreductase and conjugation by acetyltransferases and sulfotransferases in human hepatic cytosols. Cancer Res 65:2644-2652.
    • (2005) Cancer Res , vol.65 , pp. 2644-2652
    • Arlt, V.M.1    Stiborova, M.2    Henderson, C.J.3    Osborne, M.R.4    Bieler, C.A.5    Frei, E.6    Martinek, V.7    Sopko, B.8    Wolf, C.R.9    Schmeiser, H.H.10    Phillips, D.H.11
  • 8
    • 33644994856 scopus 로고    scopus 로고
    • Bioactivation of 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone: Evidence for DNA adduct formation mediated by cytochrome P450 enzymes and peroxidases
    • Arlt VM, Henderson CJ, Wolf CR, Schmeiser HH, Phillips DH, Stiborova M. 2006a. Bioactivation of 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone: Evidence for DNA adduct formation mediated by cytochrome P450 enzymes and peroxidases. Cancer Lett 234:220-231.
    • (2006) Cancer Lett , vol.234 , pp. 220-231
    • Arlt, V.M.1    Henderson, C.J.2    Wolf, C.R.3    Schmeiser, H.H.4    Phillips, D.H.5    Stiborova, M.6
  • 9
    • 33645659234 scopus 로고    scopus 로고
    • Identification of three major DNA adducts formed by the carcinogenic air pollutant 3-nitrobenzanthrone in rat lung at the C8 and N(2) position of guanine and at the N(6) position of adenine
    • Arlt VM, Schmeiser HH, Osborne MR, Kawanishi M, Kanno T, Yagi T, Phillips DH, Takamura-Enya T. 2006b. Identification of three major DNA adducts formed by the carcinogenic air pollutant 3-nitrobenzanthrone in rat lung at the C8 and N(2) position of guanine and at the N(6) position of adenine. Int J Cancer 118:2139-2146.
    • (2006) Int J Cancer , vol.118 , pp. 2139-2146
    • Arlt, V.M.1    Schmeiser, H.H.2    Osborne, M.R.3    Kawanishi, M.4    Kanno, T.5    Yagi, T.6    Phillips, D.H.7    Takamura-Enya, T.8
  • 10
    • 0031681261 scopus 로고    scopus 로고
    • Experimental colitis induced by dextran sulphate sodium in mice: Beneficial effects of sulphasalazine and olsalazine
    • Axelsson LG, Landstrom E, Bylund-Fellenius AC. 1998. Experimental colitis induced by dextran sulphate sodium in mice: Beneficial effects of sulphasalazine and olsalazine. Aliment Pharmacol Ther 12:925-934.
    • (1998) Aliment Pharmacol Ther , vol.12 , pp. 925-934
    • Axelsson, L.G.1    Landstrom, E.2    Bylund-Fellenius, A.C.3
  • 11
    • 0034563156 scopus 로고    scopus 로고
    • Metabolism and DNA-binding of 3-nitrobenzanthrone in primary rat alveolar type 11 cells, in human fetal bronchial, rat epithelial and mesenchymal cell lines
    • Borlak J, Hansen T, Yuan Z, Sikka HC, Kumar S, Schmidbauer S, Frank H, Jakob J, Seidel A. 2000. Metabolism and DNA-binding of 3-nitrobenzanthrone in primary rat alveolar type 11 cells, in human fetal bronchial, rat epithelial and mesenchymal cell lines. Polycyclic Aromat Compds 21:73-86.
    • (2000) Polycyclic Aromat Compds , vol.21 , pp. 73-86
    • Borlak, J.1    Hansen, T.2    Yuan, Z.3    Sikka, H.C.4    Kumar, S.5    Schmidbauer, S.6    Frank, H.7    Jakob, J.8    Seidel, A.9
  • 12
    • 0029130291 scopus 로고
    • Early formation of DNA adducts compared with tumor formation in a long-term tumor study in rats after administration of 2-nitrofluorene
    • Cui XS, Torndal UB, Eriksson LC, Möller L. 1995. Early formation of DNA adducts compared with tumor formation in a long-term tumor study in rats after administration of 2-nitrofluorene. Carcinogenesis 16:2135-2141.
    • (1995) Carcinogenesis , vol.16 , pp. 2135-2141
    • Cui, X.S.1    Torndal, U.B.2    Eriksson, L.C.3    Möller, L.4
  • 13
    • 0023255790 scopus 로고
    • Methodologic considerations in mucociliary clearance and lung epithelial absorption measurements
    • Dolovich MB, Jordana M, Newhouse MT. 1987. Methodologic considerations in mucociliary clearance and lung epithelial absorption measurements. Eur J Nucl Med 13:S45-S52.
    • (1987) Eur J Nucl Med , vol.13
    • Dolovich, M.B.1    Jordana, M.2    Newhouse, M.T.3
  • 14
    • 0031259941 scopus 로고    scopus 로고
    • 3-Nitrobenzanthrone, a powerful bacterial mutagen and suspected human carcinogen found in diesel exhaust and airborne particulates
    • Enya T, Suzuki H, Watanabe T, Hirayama T, Hisamatsu Y. 1997. 3-Nitrobenzanthrone, a powerful bacterial mutagen and suspected human carcinogen found in diesel exhaust and airborne particulates. Environ Sci Technol 30:2772-2776.
    • (1997) Environ Sci Technol , vol.30 , pp. 2772-2776
    • Enya, T.1    Suzuki, H.2    Watanabe, T.3    Hirayama, T.4    Hisamatsu, Y.5
  • 15
    • 0032435631 scopus 로고    scopus 로고
    • An unusual DNA adduct derived from the powerfully mutagenic environmental contaminant 3-nitrobenzanthrone
    • Enya T, Kawanishi M, Suzuki H, Matsui S, Hisamatsu Y. 1998. An unusual DNA adduct derived from the powerfully mutagenic environmental contaminant 3-nitrobenzanthrone. Chem Res Toxicol 11:1460-1467.
    • (1998) Chem Res Toxicol , vol.11 , pp. 1460-1467
    • Enya, T.1    Kawanishi, M.2    Suzuki, H.3    Matsui, S.4    Hisamatsu, Y.5
  • 16
  • 17
    • 0024565078 scopus 로고
    • Kinetics of interaction of 2-acetylaminofluorene with normal liver and carcinogen-induced hepatocyte nodules in vivo and in vitro
    • Eriksson LC, Rinaudo JA, Farber E. 1989. Kinetics of interaction of 2-acetylaminofluorene with normal liver and carcinogen-induced hepatocyte nodules in vivo and in vitro. Lab Invest 60:409-417.
    • (1989) Lab Invest , vol.60 , pp. 409-417
    • Eriksson, L.C.1    Rinaudo, J.A.2    Farber, E.3
  • 18
    • 0036675467 scopus 로고    scopus 로고
    • Occurrence and photostability of 3-nitrobenzanthrone associated with atmospheric particles
    • Feilberg A, Ohura T, Nielsen T, West Bach Poulsen M, Amagai T. 2002. Occurrence and photostability of 3-nitrobenzanthrone associated with atmospheric particles. Atmos Environ 36:3591-3600.
    • (2002) Atmos Environ , vol.36 , pp. 3591-3600
    • Feilberg, A.1    Ohura, T.2    Nielsen, T.3    West Bach Poulsen, M.4    Amagai, T.5
  • 19
    • 0014700483 scopus 로고
    • Metabolism of the carcinogen N-2-fluorenylacetamide in germ-free and conventional rats
    • Grantham PH, Horton RE, Weisburger EK, Weisburger JH. 1970. Metabolism of the carcinogen N-2-fluorenylacetamide in germ-free and conventional rats. Biochem Pharmacol 19:163-171.
    • (1970) Biochem Pharmacol , vol.19 , pp. 163-171
    • Grantham, P.H.1    Horton, R.E.2    Weisburger, E.K.3    Weisburger, J.H.4
  • 21
    • 0031393549 scopus 로고    scopus 로고
    • Nitroarene concentrations and direct-acting mutagenicity of diesel exhaust particulates fractionated by silica-gel column chromatography
    • Hayakawa K, Nakamura A, Terai N, Kizu R, Ando K. 1997. Nitroarene concentrations and direct-acting mutagenicity of diesel exhaust particulates fractionated by silica-gel column chromatography. Chem Pharm Bull (Tokyo) 45:1820-1822.
    • (1997) Chem Pharm Bull (Tokyo) , vol.45 , pp. 1820-1822
    • Hayakawa, K.1    Nakamura, A.2    Terai, N.3    Kizu, R.4    Ando, K.5
  • 22
    • 0032431522 scopus 로고    scopus 로고
    • Mutagenic specificity of a derivative of 3-nitrobenzanthrone in the supF shuttle vector plasmids
    • Kawanishi M, Enya T, Suzuki H, Takebe H, Matsui S, Yagi T. 1998. Mutagenic specificity of a derivative of 3-nitrobenzanthrone in the supF shuttle vector plasmids. Chem Res Toxicol 11:1468-1473.
    • (1998) Chem Res Toxicol , vol.11 , pp. 1468-1473
    • Kawanishi, M.1    Enya, T.2    Suzuki, H.3    Takebe, H.4    Matsui, S.5    Yagi, T.6
  • 23
    • 0035039143 scopus 로고    scopus 로고
    • The seasonal changes in the concentration of polycyclic aromatic hydrocarbons in precipitation and aerosol near Lake Balaton, Hungary
    • Kiss G, Varga-Puchony Z, Tolnai B, Varga B, Gelencser A, Krivacsy Z, Hlavay J. 2001. The seasonal changes in the concentration of polycyclic aromatic hydrocarbons in precipitation and aerosol near Lake Balaton, Hungary. Environ Pollut 114:55-61.
    • (2001) Environ Pollut , vol.114 , pp. 55-61
    • Kiss, G.1    Varga-Puchony, Z.2    Tolnai, B.3    Varga, B.4    Gelencser, A.5    Krivacsy, Z.6    Hlavay, J.7
  • 24
    • 0345708287 scopus 로고    scopus 로고
    • 3-Nitrobenzanthrone (3-NBA) induced micronucleus formation and DNA damage in human hepatoma (HepG2) cells
    • Lamy E, Kassie F, Gminski R, Schmeiser HH, Mersch-Sundermann V. 2004. 3-Nitrobenzanthrone (3-NBA) induced micronucleus formation and DNA damage in human hepatoma (HepG2) cells. Toxicol Lett 146:103-109.
    • (2004) Toxicol Lett , vol.146 , pp. 103-109
    • Lamy, E.1    Kassie, F.2    Gminski, R.3    Schmeiser, H.H.4    Mersch-Sundermann, V.5
  • 26
    • 0023905078 scopus 로고
    • The role of the intestinal microflora in the formation of mutagenic metabolites from the carcinogenic air pollutant 2-nitrofluorene
    • Möller L, Corrie M, Midtvedt T, Rafter J, Gustafsson JA. 1988. The role of the intestinal microflora in the formation of mutagenic metabolites from the carcinogenic air pollutant 2-nitrofluorene. Carcinogenesis 9:823-830.
    • (1988) Carcinogenesis , vol.9 , pp. 823-830
    • Möller, L.1    Corrie, M.2    Midtvedt, T.3    Rafter, J.4    Gustafsson, J.A.5
  • 27
    • 0028179774 scopus 로고
    • Intestinal microflora enhances formation of DNA adducts following administration of 2-NF and 2-AAF
    • Möller L, Zeisig M, Midtvedt T, Gustafsson JA. 1994. Intestinal microflora enhances formation of DNA adducts following administration of 2-NF and 2-AAF. Carcinogenesis 15:857-861.
    • (1994) Carcinogenesis , vol.15 , pp. 857-861
    • Möller, L.1    Zeisig, M.2    Midtvedt, T.3    Gustafsson, J.A.4
  • 28
    • 0037432537 scopus 로고    scopus 로고
    • Determination of 3-nitrobenzanthrone in surface soil by normal-phase high-performance liquid chromatography with fluorescence detection
    • Murahashi T, Watanabe T, Otake S, Hattori Y, Takamura T, Wakabayashi K, Hirayama T. 2003. Determination of 3-nitrobenzanthrone in surface soil by normal-phase high-performance liquid chromatography with fluorescence detection. J Chromatogr A 992:101-107.
    • (2003) J Chromatogr A , vol.992 , pp. 101-107
    • Murahashi, T.1    Watanabe, T.2    Otake, S.3    Hattori, Y.4    Takamura, T.5    Wakabayashi, K.6    Hirayama, T.7
  • 29
    • 27644451735 scopus 로고    scopus 로고
    • Oxidative stress and DNA damage caused by the urban air pollutant 3-NBA and its isomer 2-NBA in human lung cells analyzed with three independent methods
    • Nagy E, Johansson C, Zeisig M, Möller L. 2005a. Oxidative stress and DNA damage caused by the urban air pollutant 3-NBA and its isomer 2-NBA in human lung cells analyzed with three independent methods. J Chromatogr B 827:94-103.
    • (2005) J Chromatogr B , vol.827 , pp. 94-103
    • Nagy, E.1    Johansson, C.2    Zeisig, M.3    Möller, L.4
  • 30
    • 27144447686 scopus 로고    scopus 로고
    • DNA-adduct and tumor formations in rats after intratracheal administration of the urban air pollutant 3-nitrobenzanthrone
    • Nagy E, Zeisig M, Kawamura K, Hisamatsu Y, Sugeta A, Adachi S, Möller L. 2005b. DNA-adduct and tumor formations in rats after intratracheal administration of the urban air pollutant 3-nitrobenzanthrone. Carcinogenesis 26:1821-1828.
    • (2005) Carcinogenesis , vol.26 , pp. 1821-1828
    • Nagy, E.1    Zeisig, M.2    Kawamura, K.3    Hisamatsu, Y.4    Sugeta, A.5    Adachi, S.6    Möller, L.7
  • 31
    • 0033027263 scopus 로고    scopus 로고
    • Role of human N-acetyltransferases, NAT1 or NAT2, in genotoxicity of nitroarenes and aromatic amines in Salmonella typhimurium NM6001 and NM6002
    • Oda Y, Yamazaki H, Shimada T. 1999. Role of human N-acetyltransferases, NAT1 or NAT2, in genotoxicity of nitroarenes and aromatic amines in Salmonella typhimurium NM6001 and NM6002. Carcinogenesis 20:1079-1083.
    • (1999) Carcinogenesis , vol.20 , pp. 1079-1083
    • Oda, Y.1    Yamazaki, H.2    Shimada, T.3
  • 32
    • 21144450253 scopus 로고    scopus 로고
    • Synthesis, characterization, and 32P-postlabeling analysis of DNA adducts derived from the environmental contaminant 3-nitrobenzanthrone
    • Osborne MR, Arlt VM, Kliem C, Hull WE, Mirza A, Bieler CA, Schmeiser HH, Phillips DH. 2005. Synthesis, characterization, and 32P-postlabeling analysis of DNA adducts derived from the environmental contaminant 3-nitrobenzanthrone. Chem Res Toxicol 18:1056-1070.
    • (2005) Chem Res Toxicol , vol.18 , pp. 1056-1070
    • Osborne, M.R.1    Arlt, V.M.2    Kliem, C.3    Hull, W.E.4    Mirza, A.5    Bieler, C.A.6    Schmeiser, H.H.7    Phillips, D.H.8
  • 33
    • 0038045174 scopus 로고    scopus 로고
    • Sources of the atmospheric contaminants, 2-nitrobenzanthrone and 3-nitrobenzanthrone
    • Phousongphouang PT, Arey J. 2003. Sources of the atmospheric contaminants, 2-nitrobenzanthrone and 3-nitrobenzanthrone. Atmos Environ 37:3189-3199.
    • (2003) Atmos Environ , vol.37 , pp. 3189-3199
    • Phousongphouang, P.T.1    Arey, J.2
  • 34
    • 0024596570 scopus 로고
    • Kinetics of excretion of 2-acetylaminofluorene in normal and xenobiotic-treated rats and in rats with hepatocyte nodules
    • Rinaudo JA, Eriksson LC, Roomi MW, Farber E. 1989. Kinetics of excretion of 2-acetylaminofluorene in normal and xenobiotic-treated rats and in rats with hepatocyte nodules. Lab Invest 60:399-408.
    • (1989) Lab Invest , vol.60 , pp. 399-408
    • Rinaudo, J.A.1    Eriksson, L.C.2    Roomi, M.W.3    Farber, E.4
  • 35
    • 0033836892 scopus 로고    scopus 로고
    • Reductions of nitro and 9-Oxo groups of environmental nitrofluorenes by the rat mammary gland in vitro
    • Ritter CL, Decker RW, Malejka-Giganti D. 2000. Reductions of nitro and 9-Oxo groups of environmental nitrofluorenes by the rat mammary gland in vitro. Chem Res Toxicol 13:793-800.
    • (2000) Chem Res Toxicol , vol.13 , pp. 793-800
    • Ritter, C.L.1    Decker, R.W.2    Malejka-Giganti, D.3
  • 36
    • 0021428710 scopus 로고
    • Ames assay chromatograms and the identification of mutagens in diesel particle extracts
    • Salmeen IT, Pero AM, Zator R, Schuetzle D, Riley TL. 1984. Ames assay chromatograms and the identification of mutagens in diesel particle extracts. Environ Sci Technol 18:375-382.
    • (1984) Environ Sci Technol , vol.18 , pp. 375-382
    • Salmeen, I.T.1    Pero, A.M.2    Zator, R.3    Schuetzle, D.4    Riley, T.L.5
  • 37
    • 0028959549 scopus 로고
    • Mutagenicity and mutation spectra of 2-acetylaminofluorene at frameshift and base-substitution alleles in four DNA repair backgrounds of Salmonella
    • Shelton ML, DeMarini DM. 1995. Mutagenicity and mutation spectra of 2-acetylaminofluorene at frameshift and base-substitution alleles in four DNA repair backgrounds of Salmonella. Mutat Res 327:75-86.
    • (1995) Mutat Res , vol.327 , pp. 75-86
    • Shelton, M.L.1    DeMarini, D.M.2
  • 38
    • 0030995725 scopus 로고    scopus 로고
    • Molecular mechanisms of mutagenesis by aromatic amines and amides
    • Shibutani S, Grollman AP. 1997. Molecular mechanisms of mutagenesis by aromatic amines and amides. Mutat Res 376:71-78.
    • (1997) Mutat Res , vol.376 , pp. 71-78
    • Shibutani, S.1    Grollman, A.P.2
  • 39
    • 0018770035 scopus 로고
    • Mutagenic activity of chemical carcinogens and related compounds in the intraperitoneal host-mediated assay
    • Simmon VF, Rosenkranz HS, Zeiger E, Poirier LA. 1979. Mutagenic activity of chemical carcinogens and related compounds in the intraperitoneal host-mediated assay. J Natl Cancer Inst 62:911-918.
    • (1979) J Natl Cancer Inst , vol.62 , pp. 911-918
    • Simmon, V.F.1    Rosenkranz, H.S.2    Zeiger, E.3    Poirier, L.A.4
  • 41
    • 25844449697 scopus 로고    scopus 로고
    • Evaluation of genotoxicity of 3-amino-, 3-acetylamino- and 3-nitrobenzanthrone using the Ames/Salmonella assay and the comet assay
    • Watanabe T, Tomiyama T, Nishijima S, Kanda Y, Murahashi T, Hirayama T. 2005. Evaluation of genotoxicity of 3-amino-, 3-acetylamino- and 3-nitrobenzanthrone using the Ames/Salmonella assay and the comet assay. J Health Sci 51:569-575.
    • (2005) J Health Sci , vol.51 , pp. 569-575
    • Watanabe, T.1    Tomiyama, T.2    Nishijima, S.3    Kanda, Y.4    Murahashi, T.5    Hirayama, T.6
  • 42
    • 0021218739 scopus 로고
    • Health effects of diesel emissions - An update
    • Weisenberger BL. 1984. Health effects of diesel emissions - An update. J Soc Occup Med 34:90-92.
    • (1984) J Soc Occup Med , vol.34 , pp. 90-92
    • Weisenberger, B.L.1
  • 43
    • 0034695040 scopus 로고    scopus 로고
    • Bioactivation of diesel exhaust particle extracts and their major nitrated polycyclic aromatic hydrocarbon components, 1-nitropyrene and dinitropyrenes, by human cytochromes P450 1A1, 1A2, and 1B1
    • Yamazaki H, Hatanaka N, Kizu R, Hayakawa K, Shimada N, Guengerich FP, Nakajima M, Yokoi T. 2000. Bioactivation of diesel exhaust particle extracts and their major nitrated polycyclic aromatic hydrocarbon components, 1-nitropyrene and dinitropyrenes, by human cytochromes P450 1A1, 1A2, and 1B1. Mutat Res 472:129-138.
    • (2000) Mutat Res , vol.472 , pp. 129-138
    • Yamazaki, H.1    Hatanaka, N.2    Kizu, R.3    Hayakawa, K.4    Shimada, N.5    Guengerich, F.P.6    Nakajima, M.7    Yokoi, T.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.