Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: Evidence for mechanism-based inactivation of CYP1A2

Journal of Pharmacology and Experimental Therapeutics

Volumn 299, Issue 3, 2001, Pages 874-882

  Chang, Thomas K H ^a   Chen, Jie ^a   Lee, Wendy B K ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; CATALASE; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; DEETHYLAMIODARONE; DIHYDRALAZINE; FURAFYLLINE; GLUTATHIONE; IMIPRAMINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; RESVERATROL; SUPEROXIDE DISMUTASE;

ARTICLE; CATALYSIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME INACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; LIVER MICROSOME; PRIORITY JOURNAL; PROTEIN CONTENT;

ARYL HYDROCARBON HYDROXYLASES; BINDING, COMPETITIVE; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INHIBITORS; HUMANS; KINETICS; MICROSOMES, LIVER; NADP; OXAZINES; RECOMBINANT PROTEINS; STILBENES; SUBSTRATE SPECIFICITY;

EID: 0035192944     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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