Conditioned preference for sweet stimuli in OLETF rat: Effects of food deprivation

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 292, Issue 5, 2007, Pages

  De Jonghe, Bart C ^a   Hajnal, Andras ^b   Covasa, Mihai ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

CCK 1 receptor; Diet induced obesity; Food intake; Hyperphagia; Palatability

Indexed keywords

SACCHARIN; SUCROSE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; FLAVOR; FOOD DEPRIVATION; FOOD INTAKE; MALE; NONHUMAN; PALATABILITY; PRIORITY JOURNAL; RAT; STIMULUS RESPONSE; SUGAR INTAKE; SWEETNESS; TASTE ACUITY; TASTE PREFERENCE;

ANIMALS; CONDITIONING (PSYCHOLOGY); DOSE-RESPONSE RELATIONSHIP, DRUG; FOOD DEPRIVATION; RATS; RATS, INBRED OLETF; SACCHARIN; SUCROSE; SWEETENING AGENTS; TASTE;

EID: 34248166441     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00339.2006     Document Type: Article

References (51)

1. Azzara AV, Sclafani A. Flavor preferences conditioned by intragastric sugar infusions in rats: maltose is more reinforcing than sucrose. Physiol Behav 64: 535-541, 1998.
2. Berridge KC. Modulation of taste affect by hunger, caloric satiety, and sensory-specific satiety in the rat. Appetite 16: 103-120, 1991.
3. Bi S, Ladenheim EE, Schwartz GJ, Moran TH. A role for NPY overexpression in the dorsomedial hypothalamus in hyperphagia and obesity of OLETF rats. Am J Physiol Regul Integr Comp Physiol 281: R254-R260, 2001.
4. Bi S, Moran TH. Response to acute food deprivation in OLETF rats lacking CCK-A receptors. Physiol Behav 79: 655-661, 2003.
5. Blumberg S, Haba D, Schroeder M, Smith GP, Weller A. Independent ingestion and microstructure of feeding patterns in infant rats lacking CCK-1 receptors. Am J Physiol Regul Integr Comp Physiol 290: R208-R218, 2006.
6. Campbell BA. Absolute and relative sucrose preference thresholds for hungry and satiated rats. J Comp Physiol Psychol 51: 795-800, 1958.
7. Capaldi ED, Campbell DH, Sheffer JD, Bradford JP. Conditioned flavor preferences based on delayed caloric consequences. J Exp Psychol Anim Behav Process 13: 150-155, 1987.
8. Capaldi ED, Hunter MJ. Taste and odor in conditioned flavor preference learning. Anim Learn Behav 22: 355-365, 1994.
9. Capaldi ED, Myers DE. Taste preference as a function of food deprivation during original taste exposure. Anim Learn Behav 10: 211-219, 1982.
10. Capaldi ED, Myers DE, Campbell DH, Sheffer JD. Conditioned flavor preferences based on hunger level during original flavor exposure. Anim Learn Behav 11: 107-115, 1983.
11. Collier G, Bolles R. Hunger, thirst, and their interaction as determinants of sucrose consumption. J Comp Physiol Psychol 66: 633-641, 1968.
12. Covasa M, Ritter RC. Attenuated satiation response to intestinal nutrients in rats that do not express CCK-A receptors. Peptides 22: 1339-1348, 2001.
13. Covasa M, Ritter RC. Reduced CCK-induced Fos expression in the hindbrain, nodose ganglia, and enteric neurons of rats lacking CCK-1 receptors. Brain Res 1051: 155-163, 2005.
14. Crawley JN. Cholecystokinin-dopamine interactions. Trends Pharmacol Sci 12: 232-236, 1991.
15. De Jonghe BC, Di Martino C, Hajnal A, Covasa M. Brief intermittent access to sucrose differentially modulates prepulse inhibition and acoustic startle response in obese CCK-1 receptor-deficient rats. Brain Res 1052: 22-27, 2005.
16. De Jonghe BC, Hajnal A, Covasa M. Decreased gastric mechanodetection, but preserved gastric emptying, in CCK-1 receptor-deficient OLETF rats. Am J Physiol Gastrointest Liver Physiol 291: G640-G649, 2006.
17. De Jonghe BC, Hajnal A, Covasa M. Increased oral and decreased intestinal sensitivity to sucrose in obese, prediabetic CCK-A receptor-deficient OLETF rats. Am J Physiol Regul Integr Comp Physiol 288: R292-R300, 2005.
18. Elizalde G, Sclafani A. Flavor preferences conditioned by intragastric polycose infusions: a detailed analysis using an electronic esophagus preparation. Physiol Behav 47: 63-77, 1990.
19. Fedorchak PM, Bolles RC. Hunger enhances the expression of caloriebut not taste-mediated conditioned flavor preferences. J Exp Psychol Anim Behav Process 13: 73-79, 1987.
20. Graham WC, Hill DR, Woodruff GN, Sambrook MA, Crossman AR. Reduction of [125I]Bolton Hunter CCK8 and [3H]MK-329 (devazepide) binding to CCK receptors in the substantia nigra/VTA complex and its forebrain projection areas following MPTP-induced hemi-parkinsonism in the monkey. Neurosci Lett 131: 129-134, 1991.
21. Hajnal A, Covasa M, Bello NT. Altered taste sensitivity in obese, pre-diabetic OLETF rats lacking CCK-1 receptors. Am J Physiol Regul Integr Comp Physiol 289: R1675-R1686, 2005.
22. Hajnal A, Smith GP, Norgren R. Oral sucrose stimulation increases accumbens dopamine in the rat. Am J Physiol Regul Integr Comp Physiol 286: R31-R37, 2004.
23. Hamilton ME, Freeman AS. Effects of administration of cholecystokinin into the VTA on DA overflow in nucleus accumbens and amygdala of freely moving rats. Brain Res 688: 134-142, 1995.
24. Harris JA, Gorissen MC, Bailey GK, Westbrook RF. Motivational state regulates the content of learned flavor preferences. J Exp Psychol Anim Behav Process 26: 15-30, 2000.
25. Heidbreder C, Gewiss M, De Potter W, De Witte P. Regional amines levels in the rat brain following intra-accumbens cholecystokinin and intraperitoneal amphetamine pre-treatment. Arch Int Physiol Biochim Biophys 100: 267-273, 1992.
26. Herness S, Zhao FL, Lu SG, Kaya N, Shen T. Expression and physiological actions of cholecystokinin in rat taste receptor cells. J Neurosci 22: 10018-10029, 2002.
27. Holder MD. Conditioned preferences for the taste and odor components of flavors: blocking but not overshadowing. Appetite 17: 29-45, 1991.
28. Kawano K, Hirashima T, Mori S, Saitoh Y, Kurosumi M, Natori T. Spontaneous long-term hyperglycemic rat with diabetic complications. Otsuka Long-Evans Tokushima Fatty (OLETF) strain. Diabetes 41: 1422-1428, 1992.
29. Ladurelle N, Durieux C, Roques BP, Dauge V. Different modifications of the dopamine metabolism in the core and shell parts of the nucleus accumbens following CCK-A receptor stimulation in the shell region. Neurosci Lett 178: 5-10, 1994.
30. Lanca AJ, De Cabo C, Arifuzzaman AI, Vaccarino FJ. Cholecystokinergic innervation of nucleus accumbens subregions. Peptides 19: 859-868, 1998.
31. Lu SG, Zhao FL, Herness S. Physiological phenotyping of cholecystokinin-responsive rat taste receptor cells. Neurosci Lett 351: 157-160, 2003.
32. Lucas F, Azzara AV, Sclafani A. Flavor preferences conditioned by intragastric polycose in rats: more concentrated polycose is not always more reinforcing. Physiol Behav 63: 7-14, 1997.
33. Margas WM, Acharya NK, Covasa M, Hajnal A. Obese OLETF rats show augmented ingestive and motor responses to dopamine D2 receptor stimulation. Appetite 44: 329-392, 2005.
34. Moran TH, Katz LF, Plata-Salaman CR, Schwartz GJ. Disordered food intake and obesity in rats lacking cholecystokinin A receptors. Am J Physiol Regul Integr Comp Physiol 274: R618-R625, 1998.
35. Moran TH, Lee P, Ladenheim EE, Schwartz GJ. Responsivity to NPY and melanocortins in obese OLETF rats lacking CCK-A receptors. Physiol Behav 75: 397-402, 2002.
36. Moran TH, Robinson PH, Goldrich MS, McHugh PR. Two brain cholecystokinin receptors: implications for behavioral actions. Brain Res 362: 175-179, 1986.
37. Reilly S. Reinforcement value of gustatory stimuli determined by progressive ratio performance. Pharmacol Biochem Behav 63: 301-311, 1999.
38. Schwartz GJ, Whitney A, Skoglund C, Castonguay TW, Moran TH. Decreased responsiveness to dietary fat in Otsuka Long-Evans Tokushima fatty rats lacking CCK-A receptors. Am J Physiol Regul Integr Comp Physiol 277: R1144-R1151, 1999.
39. Sclafani A. Learned controls of ingestive behaviour. Appetite 29: 153-158, 1997.
40. Sclafani A. Oral and postoral determinants of food reward. Physiol Behav 81: 773-779, 2004.
41. Sclafani A, Ackroff K. Reinforcement value of sucrose measured by progressive ratio operant licking in the rat. Physiol Behav 79: 663-670, 2003.
42. Sclafani A, Ackroff K. The relationship between food reward and satiation revisited. Physiol Behav 82: 89-95, 2004.
43. Smith GP. The direct and indirect controls of meal size. Neurosci Biobehav Rev 20: 41-46, 1996.
44. Smith M, Duffy M. Consumption of sucrose and saccharine by hungry and satiated rats. J Comp Physiol Psychol 50: 65-69, 1957.
45. Takiguchi S, Takata Y, Funakoshi A, Miyasaka K, Kataoka K, Fujimura Y, Goto T, Kono A. Disrupted cholecystokinin type-A receptor (CCKAR) gene in OLETF rats. Gene 197: 169-175, 1997.
46. Wise RA. Brain reward circuitry: insights from unsensed incentives. Neuron 36: 229-240, 2002.
47. Woodruff GN, Hill DR, Boden P, Pinnock R, Singh L, Hughes J. Functional role of brain CCK receptors. Neuropeptides 19 Suppl: 45-56, 1991.
48. Yiin YM, Ackroff K, Sclafani A. Flavor preferences conditioned by intragastric nutrient infusions in food restricted and free-feeding rats. Physiol Behav 84: 217-231, 2005.
49. Yiin YM, Ackroff K, Sclafani A. Food deprivation enhances the expression but not acquisition of flavor acceptance conditioning in rats. Appetite 45: 152-160, 2005.
50. Yu WZ, Sclafani A, Delamater AR, Bodnar RJ. Pharmacology of flavor preference conditioning in sham-feeding rats: effects of naltrexone. Pharmacol Biochem Behav 64: 573-584, 1999.
51. Zverev YP. Effects of caloric deprivation and satiety on sensitivity of the gustatory system. BMC Neurosci 5: 5, 2004.