Reduced CCK-induced Fos expression in the hindbrain, nodose ganglia, and enteric neurons of rats lacking CCK-1 receptors

Brain Research

Volumn 1051, Issue 1-2, 2005, Pages 155-163

  Covasa, Mihai ^a   Ritter, Robert C ^b  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

c Fos expression; Obesity; Otsuka Long Evans Tokushima; Vagus

Indexed keywords

CHOLECYSTOKININ; CHOLECYSTOKININ A RECEPTOR; CHOLECYSTOKININ B RECEPTOR; CHOLECYSTOKININ OCTAPEPTIDE; GASTRIN RECEPTOR; PROTEIN FOS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTONOMIC NERVOUS SYSTEM; CORRELATION ANALYSIS; DUODENUM; IMMUNOREACTIVITY; INTESTINE INNERVATION; MALE; MYENTERIC PLEXUS; NODOSE GANGLION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN; RHOMBENCEPHALON; SENSORY NERVE; SOLITARY TRACT NUCLEUS; STATISTICAL SIGNIFICANCE; VAGUS NERVE; VAGUS NERVE DORSAL NUCLEUS;

ANIMALS; CHOLECYSTOKININ; DUODENUM; ENTERIC NERVOUS SYSTEM; NEURONS, AFFERENT; NODOSE GANGLION; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, INBRED OLETF; RATS, LONG-EVANS; RECEPTOR, CHOLECYSTOKININ A; RHOMBENCEPHALON; VAGUS NERVE;

EID: 22144484176     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2005.06.003     Document Type: Article

References (73)

1. K.E. Asin, P.A. Gore Jr., L. Bednarz, M. Holladay, and A.M. Nadzan Effects of selective CCK receptor agonists on food intake after central or peripheral administration in rats Brain Res. 571 1992 169 174
2. H.R. Berthoud, and L.M. Patterson Anatomical relationship between vagal afferent fibers and CCK-immunoreactive entero-endocrine cells in the rat small intestinal mucosa Acta Anat. (Basel) 156 1996 123 131
3. H.R. Berthoud, M. Kressel, H.E. Raybould, and W.L. Neuhuber Vagal sensors in the rat duodenal mucosa: distribution and structure as revealed by in vivo DiI-tracing Anat. Embryol. (Berl.) 191 1995 203 212
4. S. Bi, E.E. Ladenheim, G.J. Schwartz, and T.H. Moran A role for NPY overexpression in the dorsomedial hypothalamus in hyperphagia and obesity of OLETF rats Am. J. Physiol.: Regul., Integr. Comp. Physiol. 281 2001 R254 R260
5. S. Bi, K.A. Scott, A.S. Kopin, and T.H. Moran Differential roles for cholecystokinin a receptors in energy balance in rats and mice Endocrinology 145 2004 3873 3880
6. J.E. Blevins, B.G. Stanley, and R.D. Reidelberger Brain regions where cholecystokinin suppresses feeding in rats Brain Res. 860 2000 1 10
7. L.A. Brenner, and R.C. Ritter Intracerebroventricular cholecystokinin A-receptor antagonist does not reduce satiation by endogenous CCK Physiol. Behav. 63 1998 711 716
8. C. Broberger, K. Holmberg, T.J. Shi, G. Dockray, and T. Hokfelt Expression and regulation of cholecystokinin and cholecystokinin receptors in rat nodose and dorsal root ganglia Brain Res. 903 2001 128 140
9. D.Y. Chen, J.A. Deutsch, M.F. Gonzalez, and Y. Gu The induction and suppression of c-fos expression in the rat brain by cholecystokinin and its antagonist L364,718 Neurosci. Lett. 149 1993 91 94
10. E.S. Corp, J. McQuade, T.H. Moran, and G.P. Smith Characterization of type A and type B CCK receptor binding sites in rat vagus nerve Brain Res. 623 1993 161 166
11. E.S. Corp, M. Curcio, J. Gibbs, and G.P. Smith The effect of centrally administered CCK-receptor antagonists on food intake in rats Physiol. Behav. 61 1997 823 827
12. M. Covasa, and R.C. Ritter Attenuated satiation response to intestinal nutrients in rats that do not express CCK-A receptors Peptides 22 2001 1339 1348
13. M. Covasa, J. Grahn, and R.C. Ritter Reduced hindbrain and enteric neuronal response to intestinal oleate in rats maintained on high-fat diet Auton. Neurosci. 84 2000 8 18
14. H.E. Day, and H. Akil Evidence that cholecystokinin receptors are not involved in the hypothalamic-pituitary-adrenal response to intraperitoneal administration of interleukin-1beta J. Neuroendocrinol. 11 1999 561 568
15. B.C. De Jonghe, A. Hajnal, and M. Covasa Increased oral and decreased intestinal sensitivity to sucrose in obese, prediabetic CCK-A receptor-deficient OLETF rats Am. J. Physiol.: Regul., Integr. Comp. Physiol. 288 2005 R292 R300
16. D. Dorre, and G.P. Smith CholecystokininB receptor antagonist increases food intake in rats Physiol. Behav. 65 1998 11 14
17. C.T. Dourish, A.C. Ruckert, F.D. Tattersall, and S.D. Iversen Evidence that decreased feeding induced by systemic injection of cholecystokinin is mediated by CCK-A receptors Eur. J. Pharmacol. 173 1989 233 234
18. C.T. Dourish, W. Rycroft, and S.D. Iversen Postponement of satiety by blockade of brain cholecystokinin (CCK-B) receptors Science 245 1989 1509 1511
19. M. Dragunow, and R. Faull The use of c-fos as a metabolic marker in neuronal pathway tracing J. Neurosci. Methods 29 1989 261 265
20. L.A. Eckel, T.A. Houpt, and N. Geary Estradiol treatment increases CCK-induced c-Fos expression in the brains of ovariectomized rats Am. J. Physiol.: Regul., Integr. Comp. Physiol. 283 2002 R1378 R1385
21. K.A. Fraser, and J.S. Davison Meal-induced c-fos expression in brain stem is not dependent on cholecystokinin release Am. J. Physiol. 265 1993 R235 R239
22. A. Funakoshi, K. Miyasaka, H. Shinozaki, M. Masuda, T. Kawanami, Y. Takata, and A. Kono An animal model of congenital defect of gene expression of cholecystokinin (CCK)-A receptor Biochem. Biophys. Res. Commun. 210 1995 787 796
23. J. Glatzle, M.E. Kreis, K. Kawano, H.E. Raybould, and T.T. Zittel Postprandial neuronal activation in the nucleus of the solitary tract is partly mediated by CCK-A receptors Am. J. Physiol.: Regul., Integr. Comp. Physiol. 281 2001 R222 R229
24. D.R. Hill, and G.N. Woodruff Differentiation of central cholecystokinin receptor binding sites using the non-peptide antagonists MK-329 and L-365,260 Brain Res. 526 1990 276 283
25. Y. Hirosue, A. Inui, A. Teranishi, M. Miura, M. Nakajima, M. Okita, Y. Nakajima, N. Himori, S. Baba, and M. Kasuga Cholecystokinin octapeptide analogues suppress food intake via central CCK-A receptors in mice Am. J. Physiol. 265 1993 R481 R486
26. T. Hokfelt, K. Holmberg, T.J. Shi, and C. Broberger CCK-ergic mechanisms in sensory systems Scand. J. Clin. Lab. Invest., Suppl. 234 2001 69 74
27. A. Jagger, J. Grahn, and R.C. Ritter Reduced vagal sensory innervation of the small intestinal myenteric plexus following capsaicin treatment of adult rats Neurosci. Lett. 236 1997 103 106
28. K. Kanagawa, H. Nakamura, I. Murata, I. Yosikawa, and M. Otsuki Increased gastric acid secretion in cholecystokinin-1 receptor-deficient Otsuka Long-Evans Tokushima fatty rats Scand. J. Gastroenterol. 37 2002 9 16
29. K. Kawano, T. Hirashima, S. Mori, and T. Natori OLETF (Otsuka Long-Evans Tokushima Fatty) rat: a new NIDDM rat strain Diabetes Res. Clin. Pract. 24 1994 S317 S320 (Suppl.)
30. M. Kurosawa, V. Bucinskaite, T. Taniguchi, K. Miyasaka, A. Funakoshi, and T. Lundeberg Response of the gastric vagal afferent activity to cholecystokinin in rats lacking type A cholecystokinin receptors J. Auton. Nerv. Syst. 75 1999 51 59
31. B.H. Li, and N.E. Rowland Effects of vagotomy on cholecystokinin- and dexfenfluramine-induced Fos-like immunoreactivity in the rat brain Brain Res. Bull. 37 1995 589 593
32. P.W. Mantyh, and S.P. Hunt Evidence for cholecystokinin-like immunoreactive neurons in the rat medulla oblongata which project to the spinal cord Brain Res. 291 1984 49 54
33. G.M. Mawe The role of cholecystokinin in ganglionic transmission in the guinea-pig gall-bladder J. Physiol. 439 1991 89 102
34. L.D. Melville, G.P. Smith, and J. Gibbs Devazepide antagonizes the inhibitory effect of cholecystokinin on intake in sham-feeding rats Pharmacol. Biochem. Behav. 43 1992 975 977
35. J.H. Meyer, M. Hlinka, Y. Tabrizi, N. DiMaso, and H.E. Raybould Chemical specificities and intestinal distributions of nutrient-driven satiety Am. J. Physiol. 275 1998 R1293 R1307
36. K. Miyasaka, S. Kanai, M. Ohta, T. Kawanami, A. Kono, and A. Funakoshi Lack of satiety effect of cholecystokinin (CCK) in a new rat model not expressing the CCK-A receptor gene Neurosci. Lett. 180 1994 143 146
37. K. Miyasaka, S. Kanai, M. Ohta, A. Jimi, A. Kono, and A. Funakoshi Overexpression of cholecystokinin-B/gastrin receptor gene in the stomach of naturally occurring cholecystokinin-A receptor gene knockout rats Digestion 59 1998 26 32
38. H. Monnikes, G. Lauer, and R. Arnold Peripheral administration of cholecystokinin activates c-fos expression in the locus coeruleus/subcoeruleus nucleus, dorsal vagal complex and paraventricular nucleus via capsaicin-sensitive vagal afferents and CCK-A receptors in the rat Brain Res. 770 1997 277 288
39. H. Monnikes, G. Lauer, C. Bauer, J. Tebbe, T.T. Zittel, and R. Arnold Pathways of Fos expression in locus ceruleus, dorsal vagal complex, and PVN in response to intestinal lipid Am. J. Physiol. 273 1997 R2059 R2071
40. T.H. Moran, G.P. Smith, A.M. Hostetler, and P.R. McHugh Transport of cholecystokinin (CCK) binding sites in subdiaphragmatic vagal branches Brain Res. 415 1987 149 152
41. T.H. Moran, R. Norgren, R.J. Crosby, and P.R. McHugh Central and peripheral vagal transport of cholecystokinin binding sites occurs in afferent fibers Brain Res. 526 1990 95 102
42. T.H. Moran, P.J. Ameglio, G.J. Schwartz, and P.R. McHugh Blockade of type A, not type B, CCK receptors attenuates satiety actions of exogenous and endogenous CCK Am. J. Physiol. 262 1992 R46 R50
43. T.H. Moran, L.F. Katz, C.R. Plata-Salaman, and G.J. Schwartz Disordered food intake and obesity in rats lacking cholecystokinin A receptors Am. J. Physiol. 274 1998 R618 R625
44. M. Ohta, S. Kanai, Y. Sato, M. Masuda, T. Takahashi, A. Jimi, A. Funakoshi, and K. Miyasaka Mechanism of delayed gastric emptying in naturally occurring CCK-A receptor gene knockout (OLETF) rats Jpn. J. Physiol. 50 2000 443 448
45. L.M. Patterson, H. Zheng, S.M. Ward, and H.R. Berthoud Immunohistochemical identification of cholecystokinin A receptors on interstitial cells of Cajal, smooth muscle, and enteric neurons in rat pylorus Cell Tissue Res. 305 2001 11 23
46. G. Paxinos, and C. Watson The Rat Brain in Stereotaxic Coordinates 1997 Academic Press San Diego
47. H.E. Raybould Capsaicin-sensitive vagal afferents and CCK in inhibition of gastric motor function induced by intestinal nutrients Peptides 12 1991 1279 1283
48. H.E. Raybould, and Y. Tache Cholecystokinin inhibits gastric motility and emptying via a capsaicin-sensitive vagal pathway in rats Am. J. Physiol. 255 1988 G242 G246
49. R.D. Reidelberger, G. Varga, and T.E. Solomon Effects of selective cholecystokinin antagonists L364,718 and L365,260 on food intake in rats Peptides 12 1991 1215 1221
50. R.D. Reidelberger, D. Heimann, L. Kelsey, and M. Hulce Effects of peripheral CCK receptor blockade on feeding responses to duodenal nutrient infusions in rats Am. J. Physiol.: Regul., Integr. Comp. Physiol. 284 2003 R389 R398
51. L. Rinaman, J.G. Verbalis, E.M. Stricker, and G.E. Hoffman Distribution and neurochemical phenotypes of caudal medullary neurons activated to express cFos following peripheral administration of cholecystokinin J. Comp. Neurol. 338 1993 475 490
52. R.C. Ritter Gastrointestinal mechanisms of satiation for food Physiol. Behav. 81 2004 249 273
53. R.C. Ritter, and E.E. Ladenheim Capsaicin pretreatment attenuates suppression of food intake by cholecystokinin Am. J. Physiol. 248 1985 R501 R504
54. R.C. Ritter, M. Covasa, and C.A. Matson Cholecystokinin: proofs and prospects for involvement in control of food intake and body weight Neuropeptides 33 1999 387 399
55. A.I. Sayegh, and R.C. Ritter CCK-A receptor activation induces fos expression in myenteric neurons of rat small intestine Regul. Pept. 88 2000 75 81
56. A.I. Sayegh, and R.C. Ritter Vagus nerve participates in CCK-induced Fos expression in hindbrain but not myenteric plexus Brain Res. 878 2000 155 162
57. A.I. Sayegh, and R.C. Ritter Cholecystokinin activates specific enteric neurons in the rat small intestine Peptides 24 2003 237 244
58. R.R. Schick, V. Schusdziarra, J. Mossner, J. Neuberger, B. Schroder, R. Segmuller, V. Maier, and M. Classen Effect of CCK on food intake in man: physiological or pharmacological effect? Z. Gastroenterol. 29 1991 53 58
59. I.W. Schutte, L.M. Akkermans, and A.B. Kroese CCKA and CCKB receptor subtypes both mediate the effects of CCK-8 on myenteric neurons in the guinea-pig ileum J. Auton. Nerv. Syst. 67 1997 51 59
60. I.W. Schutte, K.B. Hollestein, L.M. Akkermans, and A.B. Kroese Evidence for a role of cholecystokinin as neurotransmitter in the guinea-pig enteric nervous system Neurosci. Lett. 236 1997 155 158
61. G.J. Schwartz, A. Whitney, C. Skoglund, T.W. Castonguay, and T.H. Moran Decreased responsiveness to dietary fat in Otsuka Long-Evans Tokushima fatty rats lacking CCK-A receptors Am. J. Physiol. 277 1999 R1144 R1151
62. E. Shoji, T. Okumura, S. Onodera, N. Takahashi, K. Harada, and Y. Kohgo Gastric emptying in OLETF rats not expressing CCK-A receptor gene Dig. Dis. Sci. 42 1997 915 919
63. T.L. Sills, and F.J. Vaccarino Individual differences in the feeding response to CCKB antagonists: role of the nucleus accumbens Peptides 17 1996 593 599
64. S.M. Simasko, J. Wiens, A. Karpiel, M. Covasa, and R.C. Ritter Cholecystokinin increases cytosolic calcium in a subpopulation of cultured vagal afferent neurons Am. J. Physiol.: Regul., Integr. Comp. Physiol. 283 2002 R1303 R1313
65. G.P. Smith, C. Jerome, B.J. Cushin, R. Eterno, and K.J. Simansky Abdominal vagotomy blocks the satiety effect of cholecystokinin in the rat Science 213 1981 1036 1037
66. E.H. South, and R.C. Ritter Capsaicin application to central or peripheral vagal fibers attenuates CCK satiety Peptides 9 1988 601 612
67. C. Sternini, H. Wong, T. Pham, R. De Giorgio, L.J. Miller, S.M. Kuntz, J.R. Reeve, J.H. Walsh, and H.E. Raybould Expression of cholecystokinin A receptors in neurons innervating the rat stomach and intestine Gastroenterology 117 1999 1136 1146
68. M. Storr, D. Sattler, A. Hahn, V. Schusdziarra, and H.D. Allescher Endogenous CCK depresses contractile activity within the ascending myenteric reflex pathway of rat ileum Neuropharmacology 44 2003 524 532
69. S.A. Wank Cholecystokinin receptors Am. J. Physiol. 269 1995 G628 G646
70. S.A. Wank, R. Harkins, R.T. Jensen, H. Shapira, A. de Weerth, and T. Slattery Purification, molecular cloning, and functional expression of the cholecystokinin receptor from rat pancreas Proc. Natl. Acad. Sci. U. S. A. 89 1992 3125 3129
71. D.P. Yox, H. Stokesberry, and R.C. Ritter Vagotomy attenuates suppression of sham feeding induced by intestinal nutrients Am. J. Physiol. 260 1991 R503 R508
72. D.P. Yox, L. Brenner, and R.C. Ritter CCK-receptor antagonists attenuate suppression of sham feeding by intestinal nutrients Am. J. Physiol. 262 1992 R554 R561
73. T.T. Zittel, J. Glatzle, M.E. Kreis, M. Starlinger, M. Eichner, H.E. Raybould, H.D. Becker, and E.C. Jehle C-fos protein expression in the nucleus of the solitary tract correlates with cholecystokinin dose injected and food intake in rats Brain Res. 846 1999 1 11